Protective Effects of Methotrexate against Proatherosclerotic Cytokines: A Review of the Evidence by Arduino A. Mangoni, Angelo Zinellu, Salvatore Sotgia, Ciriaco Carru, Matteo Piga, Gian Luca Erre

“…The presence of a chronic systemic proinflammatory state in this patient group disrupts the structural and functional integrity of the endothelium and the arterial wall, favouring the onset and progression of atherosclerosis. …”
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The double role of GABAergic system in systemic tumors: an updated review by Xueyang Yang, Qianhe Zu, Luxuan Wang, Chunhui Li, Lijian Zhang, Lijian Zhang

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Unveiling the potential of far-UVC: Assessing irradiance and dose-response for microbial inactivation in UV systems by Sudhanshu Pandey, Aku Karvinen, Jani Hakala

“…These parameters include diffuse irradiance (UV lamp efficiency), UV transmittance (UVT), and Reynolds number. An user-defined function calculates UV dosages received by microbes traversing the system. …”
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Genetic polymorphism of interferon regulatory factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation. by Xiaobo Yu, Bajin Wei, Yifan Dai, Min Zhang, Jian Wu, Xiao Xu, Guoping Jiang, Shusen Zheng, Lin Zhou

“…<h4>Conclusions</h4>IRF5, which transcriptionally activates inflammatory cytokines, is genetically associated with acute rejection and might function as a risk factor for acute rejection of liver transplantations.…”
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Rett Syndrome: From Bed to Bench by Shih-Ming Weng, Mark E.S. Bailey, Stuart R. Cobb

“…Neurophysiological studies in Mecp2-mutant mice consistently report alterations in synaptic function, notably, defects in synaptic plasticity. …”
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Hippocampal subfield volume alterations and associations with severity measures in long COVID and ME/CFS: A 7T MRI study. by Kiran Thapaliya, Sonya Marshall-Gradisnik, Natalie Eaton-Fitch, Markus Barth, Maira Inderyas, Leighton Barnden

“…The neurocognitive impairment in both conditions might be linked to alterations in the hippocampal subfields. …”
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Spinal Cord Hemisection Facilitates Aromatic L-Amino Acid Decarboxylase Cells to Produce Serotonin in the Subchronic but Not the Chronic Phase by Bushra Azam, Jacob Wienecke, Dennis Bo Jensen, Aleena Azam, Mengliang Zhang

“…These results suggest that plastic changes of the 5-HT system might happen primarily in the subchronic phase and for longer period its function could be compensated by plastic changes of other intrinsic and/or supraspinal modulation systems.…”
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Recent advances in stem cell-based therapies for type 1 diabetes: A glimpse into the future by Ahmed Hassanein, Saghir Akhtar

“…These therapies aim to restore long-term endogenous β-cell function in all T1DM patients, provided they can avoid immune recognition and rejection by the host. …”
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A Case Report: Electrotonic Modulation‐Related T‐Wave Over‐Sensing After Left Bundle Branch Pacing by Linlin Li, Manxin Lin, Jincun Guo, Qiang Li, Fanqi Meng, Xinyi Huang, Simei Chen, Binni Cai

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Exercise in atherosclerosis: its beneficial effects and underlying mechanism by Meng-ting Yin, Meng-ting Yin, Meng-ting Yin, Meng-ting Yin, Liang Guo, Liang Guo, Liang Guo, Liang Guo

“…Fully understanding the effects and mechanisms of exercise in reducing atherosclerosis might open doors to developing safe and effective interventions.…”
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Modulation of adult hippocampal neurogenesis by interleukin 1 signaling by Maria I. Smirnova, Ning Quan

“…Current literature also shows AHN participates in normal functions of the brain in parallel to IL-1. This mini-review analyzes how IL-1 might positively or negatively modulate AHN and the implications of the relationship between IL-1 and AHN on health and disease. …”
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Combination of the ranking method and time reversal asymmetry for evaluating the quality of translations: a case study on passages from works by Edgar Allan Poe and Kenzaburo Oe by Kazuya Hayata

“…To examine the correlations of syllabic sequences, regressions are made on both a long-tailed (LT) and a short-tailed function. The validity of our method for revealing correlations in the Markovian sequences of Japanese syllabics is confirmed by comparing the results of two original examples: popularity ranking of boy names and passages from a Japanese novel. …”
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Relationship between ovary locule formation and content of related metabolites of stem apices during floral bud differentiation stages in tomato (Lycopersicon esculentum Mill.) see... by LI Yue, LI Tian-lai, WANG Dan

“…To fully understand function of related metabolites of ovary locule formation in tomato, two varieties, ovary multi-locule (MLK1) and few-locule (FL1), were used. …”
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P300 development across the lifespan: a systematic review and meta-analysis. by Rik van Dinteren, Martijn Arns, Marijtje L A Jongsma, Roy P C Kessels

“…The P300 latency possibly indexes neural speed or brain efficiency. The P300 amplitude might index neural power or cognitive resources, which increase with maturation.…”
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Gut Microbiota, Circulating Metabolites and Risk of Endometriosis: A Two-Step Mendelian Randomization Study by Yang Hua

“…Two-step MR analysis indicated that specific microbial taxa, notably genus Enterorhabdus and order Selenomonadales, might function as mediators linking circulating metabolites to the risk of EMs. …”
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Anti-Mullerian Hormone and Its Association with Polycystic Ovarian Syndrome: An Analytic Study by Oola Qzwini

“…AMH is a clinical marker of female reproductive potential, and we aimed to determine whether it might be associated with PCOS. The criteria for diagnosis of PCOS are irregular ovulatory function (oligomenorrhea or amenorrhea), evidence of hyperandrogenism (biochemical or clinical), and the presence of a polycystic ovarian picture on sonography. …”
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High-fidelity EEG feature-engineered taxonomy for bruxism and PLMS prognostication through pioneering and avant-garde ML frameworks by Shivam Tiwari, Deepak Arora, Barkha Bhardwaj

“…Using K-Nearest Neighbors (KNN), Artificial Neural Networks (ANN), and Support Vector Machines (SVM) with Radial Basis Function (RBF), Bruxism categorization was accomplished. …”
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Logistical constraints lead to an intermediate optimum in outbreak response vaccination. by Yun Tao, Katriona Shea, Matthew Ferrari

“…We use stochastic simulation to identify the optimum vaccination diffusion rate as a function of population density, interaction scale, transmissibility, and vaccine intensity. …”
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Genotoxicity of beauvericin by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Tanja Schwerdtle, Katharina Vejdovszky, Barbara Viviani, Emanuela Corsini, Ludovic Le Hégarat, Hans Steinkellner, Margherita Bignami

“…These include increased reactive oxygen species, induction of cell cycle arrest and apoptosis, associated with interference in mitochondrial function and cell signalling. There was no compelling evidence of inflammatory and immunosuppressive effects. …”
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Spatial expression of glucagon-like peptide 1 receptor and caveolin-1 in hepatocytes with macrovesicular steatosis in non-alcoholic steatohepatitis by Hiroaki Yokomori, Wataru Ando

“…Glucagon-like peptide 1 receptor (GLP-1R) mediates β cell function. Its receptor agonists, currently used to treat type 2 diabetes mellitus, might be effective against NASH. …”
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