Model order reduction for left ventricular mechanics via congruency training. by Paolo Di Achille, Jaimit Parikh, Svyatoslav Khamzin, Olga Solovyova, James Kozloski, Viatcheslav Gurev

“…Computational models of the cardiovascular system and specifically heart function are currently being investigated as analytic tools to assist medical practice and clinical trials. …”
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Monocephalus dipygus in a 4-month-old mixed-breed puppy: clinical, radiographic, ultrasonographic, karyotyping and surgical intervention by Lorena Elizabeth Chalco-Torres, Ana Elizabeth Guerrero López, Mauro Nirchio Tursellino

“…Cytogenetic analysis was conducted to investigate potential chromosomal abnormalities underlying these congenital anomalies, as we hypothesized that these malformations might be linked to chromosomal aberrations. The successful surgical removal of the supernumerary limb significantly improved the dog’s mobility. …”
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Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server by Sunghoon Jung, Se-Eun Bae, Insung Ahn, Hyeon S. Son

“…Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. …”
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Significant association of estrogen receptor binding site variation with bipolar disorder in females. by Lisette Graae, Robert Karlsson, Silvia Paddock

“…A nucleotide change in the binding sequence might alter the binding efficiency, which could affect transcription levels of nearby genes. …”
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Role of necroptosis and immune infiltration in essential thrombocytosis by Guangming Li, Ying Guo, Yuanyuan Zhang

“…Conclusions Necroptosis might drive the progression of ET via stimulating immune infiltration and immune responses. …”
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‘...the opium of the people’? Religiosity in socialist new towns by Márton Berki, Brigitta Sivadó

“…On the other hand, a remarkable religious revival might have been expected in the wake of the politico-economic transition, with the advent of the ‘free world’. …”
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Evidence for reduced synaptic protein SNAP-25 in cerebrospinal fluid in major depressive disorder and schizophrenia by Patrick Oeckl, Petra Steinacker, Markus Otto, Steffen Halbgebauer, MHD Rami Al Shweiki, Samir Abu-Rumeileh, Naguib Mechawar, Carlos Schönfeldt-Lecuona, Lorenzo Barba, Leonie Werner, Alexander Tarabuko, Ilyas Al-Ali, Christopher R Pryce, Nadia Cattane, Giulia Poggi, Heiko Graf, Henning Großkopf, Laura Meier, Hugh Marston, Klaus D Bornemann, Bastian Hengerer, Karin M Danzer

“…We propose that CSF SNAP-25 level might represent an integrated readout of reduced synaptic function, rather than of synaptic degeneration, in MDD. …”
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Prognostic value of LncRNA SH3BP5-AS1 in non-small cell lung cancer and its regulatory effect on tumor progression by Cong Meng, Aihua Zang, Fengcai Du

“…Compared with patients showing SH3BP5-AS1 low-expression, those with SH3BP5-AS1 high-expression possessed a more favorable progression-free survival time. SH3BP5-AS1 might function as an autonomous prognostic biomarker for NSCLC. …”
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Rosmarinic acid regulates lipid accumulation through lipid metabolism and anti-inflammatory by Chunxiu Lin, Zhuobin Li, Yun Chen, Jingrui Luo, Guo Liu, Chi-Tang Ho, Yong Cao, Yunjiao Chen

“…In addition, RA improved the integrity of intestinal barrier function in C. elegans. RNA sequencing and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) comprehensively revealed that the lipid-lowering mechanism mediated by RA might involve lipid metabolism and anti-inflammatory pathways. …”
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Asthma and cognitive dysfunction in older adults: the mediating role of systemic immune-inflammation index by Jianqin Hu, Honggang Ma, Zhiyuan Ning, Qi Xu, Ji Luo, Xuanfei Jiang, Bing Zhang, Ying Liu

“…Asthma diagnosis was confirmed using the MCQ010 questionnaire, cognitive function assessed through the Digit Symbol Substitution Test (DSST). …”
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Interactions between Gut Microbiota and Immunomodulatory Cells in Rheumatoid Arthritis by Huihui Xu, Hongyan Zhao, Danping Fan, Meijie Liu, Jinfeng Cao, Ya Xia, Dahong Ju, Cheng Xiao, Qingdong Guan

“…Immunomodulatory cells (ICs) play a critical role in the maintenance and homeostasis of normal immune function and in the pathogenesis of RA. The human gastrointestinal tract is inhabited by trillions of commensal microbiota on the mucosal surface that play a fundamental role in the induction, maintenance, and function of the host immune system. …”
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Gender-Dependent Association Between Thyroid Hormones and Severity of Coronary Artery Disease by SYNTAX Score by Ramin Eskandari, Mona Vatandoost, Saeid Nourian, Yousef Rezaei

“… Thyroid function has been shown to be associated with cardiovascular diseases. …”
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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway by Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

“…Furthermore, network pharmacology analysis suggested that AE's treatment of renal fibrosis might function via the PI3K/Akt/GSK3β signaling pathway. …”
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Expert Consensus on Vitamin B6 Therapeutic Use for Patients: Guidance on Safe Dosage, Duration and Clinical Management by Schellack N, Yotsombut K, Sabet A, Nafach J, Hiew FL, Kulkantrakorn K

“…These key recommendations encompass the function of vitamin B6, complications due to vitamin B6 deficiency, dosage recommendations, adverse events, and monitoring guidance throughout the course of treatment. …”
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The Association between DRD3 Ser9Gly Polymorphism and Depression Severity in Parkinson’s Disease by Yan Zhi, Yongsheng Yuan, Qianqian Si, Min Wang, Yuting Shen, Lina Wang, Hui Zhang, Kezhong Zhang

“…Our aim was to investigate the potential effect of DRD3 Ser9Gly polymorphism on modulating resting-state brain function and associative clinical manifestations in PD patients. …”
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Protective Effects of Gardenia Fruit Derived Exosome-like Nanoparticles Towards Rotenone-induced Damage in PC12 Cells by Haobo WANG, Yan WANG, Zhouzhe LAN, Weikang SHEN, Chunlian QIN, Wen CHEN, Lizhou XU

“…In addition, GDENs could also increase the number of mitochondria in PC12 cells. This elevation might be related to the promotion of mitochondrial biosynthesis and the improvement of its function by GDENs, thereby contributing to the energy metabolism and function maintenance of cells. …”
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Bright light therapy in Parkinson’s disease: a pilot study on visual pathway improvements by Wei-ye Xie, Hui Lou, Jia-ying Liu, Jie-yun Yin, Tian-qi Zhang, Cheng-jie Mao, Fen Wang, Chun-feng Liu, Yun Shen

“…Results Excessive daytime sleepiness, anxiety, life quality and autonomic function were improved after BLT. Compared with DLT, bilateral ΔN95 latencies for PERG and ΔP100 latencies for VEP were improved after BLT. …”
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A Norwegian cohort with STAT1-related disease – further expanding the clinical phenotype by Karen Helene Bronken Martinsen, Karen Helene Bronken Martinsen, Torstein Øverland, Asbjørg Stray-Pedersen, Tore G. Abrahamsen, Børre Fevang, Børre Fevang, Hans Christian Erichsen Landsverk, Hans Christian Erichsen Landsverk

“…Eighteen individuals had STAT1 gain-of-function (GOF) variants. Chronic mucocutaneous candidiasis (CMC) was the most common manifestation, observed in 94% of patients. …”
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Key Features of Effective Yoga Interventions in Addition to Standard Medical Treatment for Rheumatoid Arthritis: A Systematic Review and Meta‐Analysis by Isha Biswas, Jaspreet Kaur, Fiona Pearce, Sarah Lewis, Kaushik Chattopadhyay

“…Seventeen databases were searched for randomized controlled trials (RCTs) assessing yoga's effectiveness in treating RA outcomes (disease activity score, pain, and function). Meta‐analyses and narrative synthesis were conducted. …”
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Subclinical Hypothyroidism and Type 2 Diabetes: A Systematic Review and Meta-Analysis. by Cheng Han, Xue He, Xinghai Xia, Yongze Li, Xiaoguang Shi, Zhongyan Shan, Weiping Teng

“…It is necessary to screen thyroid function in patients with T2DM, and appropriate individualized treatments in addition to thyroid function test should be given to T2DM patients with SCH as well.…”
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