Hybrid virtual screening and molecular dynamics approach for identification of allosteric modulator of EAAT2 by Chennu Manisha, Nagarjuna Palathoti, Jagdish Chand, Akey Krishna Swaroop, Jubie Selvaraj, B.R. Prashantha Kumar, Prisil Naveentha X, Brindha Durairaj, Antony Justin

“…Therefore, compounds that enhance EAAT2 function by reducing oxidative stress and excitotoxicity might be neuroprotective. …”
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Thyroid Dysfunction and Autoantibodies Association with Hypertensive Disorders during Pregnancy by Azin Alavi, Khadijeh Adabi, Sepideh Nekuie, Elham Kazemi Jahromi, Mehrdad Solati, Alireza Sobhani, Hoda Karmostaji, Alireza Shahab Jahanlou

“…The samples were nulliparous and matched based on age and gestational age and none of them had previous history of hypertensive or thyroid disorders and other underlying systemic diseases or took medication that might affect thyroid function. Their venous blood samples were collected using electrochemiluminescence and ELISA method and thyroid hormones and TSH and autoantibodies were measured. …”
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Decentralized optimization for coordinated participation of local energy communities in ancillary services markets with desired energy sharing and costs by Pierluigi Siano, Marialaura Di Somma, Mohammad Dolatabadi

“…Under a coordinated management obtained with the proposed decentralized optimization, each LEC’s objective function remains within roughly 1 % of its ideal solution. …”
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Long covid and mental and physical health: A cross‐sectional study of adults in California by Tyler B. Mason, Tara K. Knight, Ryan Lee, Shirin E. Herzig, Daniella Meeker, Jason N. Doctor

“…., diagnosed long covid), who believe they do or might have long covid (i.e., self‐reported long covid), and people without long covid. …”
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Effects of different anesthetic drugs on electroretinography in mice by Chaofeng Yu, Xue Wang, Kunhuan Yang, Yun Han, Shiying Li, Yi Wang

“…Abstract Electrophysiology (ERG) is widely used for retinal function assessment, but the effects of different anesthetics on ERG recordings, particularly in degenerated retinas, remain unclear. …”
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Transcriptomic and metabolomic analyses of Tartary buckwheat roots during cadmium stress by Hanmei Du, Lu Tan, Changhe Wei, Shengchun Li, Zhou Xu, Qinghai Wang, Qiuzhu Yu, Peter R. Ryan, Hongyou Li, An’hu Wang

“…Our results indicate that Cd stress affects cell wall function and GSH metabolism and that changes in these pathways might contribute to mechanisms of Cd tolerance in Tartary buckwheat.…”
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Pre-transplant residual diuresis and oxalic acid concentration influence kidney graft survival. by Gideon Post Hospers, Mirjam Laging, Wesley J Visser, Pedro Miranda Afonso, Jeroen Ghp Verhoeven, Ingrid Ram Mertens Zur Borg, Dennis A Hesselink, Anneke M E de Mik-van Egmond, Michiel G H Betjes, Madelon van Agteren, David Severs, Jacqueline van de Wetering, Robert Zietse, Michel J Vos, Ido P Kema, Marcia M L Kho, Marlies E J Reinders, Joke I Roodnat

“…High oxalic acid concentrations at transplantation might negatively influence kidney transplant function. …”
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Left Ventricular Diastolic Dysfunction in Dialysis Patients Assessed by Novel Speckle Tracking Strain Rate Analysis: Prevalence and Determinants by Mihály K. de Bie, Nina Ajmone Marsan, André Gaasbeek, Jeroen J. Bax, Marc Groeneveld, Bas A. Gabreels, Victoria Delgado, Ton J. Rabelink, Martin J. Schalij, J. Wouter Jukema

“…Novel echocardiographic speckle tracking strain analysis permits accurate assessment of left ventricular diastolic function, independent of loading conditions and taking all myocardial segments into account. …”
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Acute Hypobaric and Hypoxic Preconditioning Reduces Myocardial Ischemia-Reperfusion Injury in Rats by Hirofumi Terada, Naoyuki Hirata, Yasuaki Sawashita, Sho Ohno, Yusuke Yoshikawa, Michiaki Yamakage

“…After each exposure, 30 min of myocardial ischemia was followed by 60 min of reperfusion. Cardiac function and infarct size were determined after reperfusion. …”
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Robust and reproducible human intestinal organoid-derived monolayer model for analyzing drug absorption by Kai Tanaka, Tatsuki Mochizuki, Shogo Baba, Shigeto Kawai, Kiyotaka Nakano, Tatsuhiko Tachibana, Kohsuke Uchimura, Atsuhiko Kato, Takashi Miyayama, Tomohito Yamaguchi, Hiroshi Nishihara, Kimio Terao, Yasutaka Kato

“…Our model showed similarity to primary enterocytes in terms of the drug absorption-related gene expression profile, tight barrier function, tolerability toward artificial bile juice, drug transporter and metabolizing enzyme function, and nuclear receptor activity. …”
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Efficacy of Acupuncture for Diminished Ovarian Reserve: A Randomized Controlled Trial Protocol by Zhao Y, Liu L, Tao X, Gan D, Lai Y, Tian C, Huang L, Huang Y, Yang J

“…The primary outcome was the change in ovarian function modeling as assessed by four metrics: age, ovarian reserve markers such as follicle-stimulating hormone (FSH) and anti-Müllerian hormone (AMH) in the Ovarian Reserve Function Prediction Tool (OvaRePred). …”
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Hashimoto’s Thyroiditis Can Occur Not Only in The Adolescence Period But also in Children Under Five Years of Age by Amine Aktar Karakaya, Edip Ünal, Aslı Beştaş, Fatma Özyalın

“…Conclusion: Thyroid function test results of patients with Hashimoto’s thyroiditis may vary in the follow-up period. …”
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From Railroad to Highway: Shifting Use of Land Transportation System in the Northern Coast of Central Java by Endah Sri Hartatik

“…However, due to the decline in plantation production, the function of trains decreased as well. During the New Order era which focused on agrarian farming system, trains’ function as transportation went down and replaced by highway. …”
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Oxygen-Dependent Blood Processes in Beck's Sarcoidosis by N. V. Glutkina, V. V. Zinchuk

“…Parameters of blood oxygen transport function and free radical lipid oxidation, as well as the content of nitrogen monoxide and hydrogen sulfide gas transmitters were assessed in the blood of 75 patients (41 women; 34 men) with Beck's sarcoidosis, stage 2 (the pulmonary mediastinal form).Results. …”
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Dealing with data gaps for TianQin with massive black hole binary signal by Lu Wang, Hong-Yu Chen, Xiangyu Lyu, En-Kun Li, Yi-Ming Hu

“…Abstract Space-borne gravitational wave detectors like TianQin might encounter data gaps due to factors like micro-meteoroid collisions or hardware failures. …”
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Effects of Esketamine Combined With Remimazolam Tosylate on Hemodynamics During Cardiovascular Anesthesia by Lei Xi, Hui Liu, XiaoJuan Tang, ZhenZhen Jiang

“…This approach might provide significant benefits in cardiovascular anesthesia.…”
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Evolutionary Trajectories of Methionine Metabolism in Mycobacterium and Its Application to Engineer a Vitamin B12 Whole‐Cell Ribosensor by Elena Campos‐Pardos, Laura Sanz‐Asensio, Sandra Pérez‐Jiménez, Inmaculada Yruela, Bruno Contreras‐Moreira, Alejandro Toledo‐Arana, Jesús Gonzalo‐Asensio

“…Here, we hypothesise that this discrepant phenotype might impact the function of B12‐dependent enzymes. …”
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Urobilin Derived from Bilirubin Bioconversion Binds Albumin and May Interfere with Bilirubin Interacting with Albumin: Implications for Disease Pathology by Kevin I. Williams, Priyanka Suryadevara, Chang-Guo Zhan, Terry D. Hinds, Zachary A. Kipp

“…<b>Conclusions:</b> The in silico docking analysis and autofluorescence results demonstrate that urobilin binds to albumin and might compete with bilirubin. This is the first study to identify a urobilin-binding protein and the important aspects of its physiological function and transport in circulation.…”
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Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism by Tae Jun Lee, Andrea Santeford, Kristen M. Pitts, Carla Valenzuela Ripoll, Ryo Terao, Zhen Guo, Mualla Ozcan, Dagmar Kratky, Christina Christoffersen, Ali Javaheri, Rajendra S. Apte

“…Because of its importance in age-related diseases, we hypothesize that apolipoprotein M (ApoM), a lipocalin that binds sphingosine-1-phosphate (S1P), might restore lipid homeostasis and retinal function in AMD. …”
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FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils by Peiyuan Li, Wenbin Ji, Baotong Zhang, Haowen Jia, Jinmiao Wang, Zhaonan Sun, Yifan Wang, Weiwei Wang, Feng Qi

“…The effect on neutrophil function after blocking formyl peptide receptor 1 (FPR1) was tested in vitro experiments. …”
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