L-Carnitine: An Antioxidant Remedy for the Survival of Cardiomyocytes under Hyperglycemic Condition by Fernanda Vacante, Pamela Senesi, Anna Montesano, Alice Frigerio, Livio Luzi, Ileana Terruzzi

“…Our results suggest that LC might ameliorate metabolic aspects of hyperglycemic cardiac cells. …”
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Hsa-miR-21 promoted the progression of lung adenocarcinoma by regulating LRIG1 expression by Li Liu, Xinhua Liu, Chengpeng Gao, Meijuan Liu, Mengmeng Peng, Leqiang Wang

“…In LUAD patients, hsa-miR-21 expression was observably related to LRIG1 expression. Hsa-miR-21 might negatively modulate the LRIG1 expression in LUAD. …”
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Increased Frequency of Bone Marrow T Follicular Helper Cells in Patients with Immune-Related Pancytopenia by Hong Yu, Jiangbo Zhang, Rong Fu, Hui Liu, Huaquan Wang, Kai Ding, Yihao Wang, Lijuan Li, Honglei Wang, Zonghong Shao

“…It was indicated that dysregulated Tfh cells might be involved in the pathogenesis of IRP and that inhibition of Tfh cells effector molecules might provide opportunities for new therapeutic approaches to IRP and even other human autoimmune diseases.…”
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Fish Biodiversity at Kawadighi Haor of Northeastern Bangladesh: Addressing Fish Diversity, Production and Conservation Status by Md. Abu Hena Mostofa Kamal, Md. Abu Kawsar, Debasish Pandit, Mrityunjoy Kunda, Khushnud Tabassum, Md. Tariqul Alam

“…The findings showed that Kawadighi Haor is a very productive and biodiversity-rich inland open waterbody that may function as a mother fishery. For the protection of current fisheries resources, multiple approaches including public awareness campaigns might be beneficial.…”
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Field and Laboratory Studies on Pathological and Biochemical Characterization of Microcystin-Induced Liver and Kidney Damage in the Phytoplanktivorous Bighead Carp by Li Li, Ping Xie, Longgen Guo, Zhixin Ke, Qiong Zhou, Yaqin Liu, Tong Qiu

“…Bighead carp in field and laboratory studies showed a progressive recovery of structure and function in terms of histological, cellular, and biochemical features. …”
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MiR-595 and Cldnd1: Potential related factors for bone loss in postmenopausal women with hip osteoporotic fracture. by Sun Jingyue, Liu Peixin, Wang Xiao

“…<h4>Background</h4>Recently researches have reported that miRNA and its target genes are associated with osteoporosis. MiRNA and mRNA might be potential diagnostic markers for osteoporosis.…”
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SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway by Qi Song, Lina He, Jing Feng

“…Univariate and multivariate Cox regression analyses showed that SQLE might have the potency to serve as an independently prognostic biomarker in OS. …”
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Serum Levels of Asymmetric Dimethylarginine and Apelin as Potential Markers of Vascular Endothelial Dysfunction in Early Rheumatoid Arthritis by Manuela Di Franco, Francesca Romana Spinelli, Alessio Metere, Maria Chiara Gerardi, Virginia Conti, Francesca Boccalini, Cristina Iannuccelli, Francesco Ciciarello, Luciano Agati, Guido Valesini

“…Impaired endothelial function represents the early stage of atherosclerosis, which is typically associated with systemic inflammatory diseases like rheumatoid arthritis (RA). …”
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Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic SteatosisSummary by Xiao-lin Wang, Jia-hao He, Ping Xie, Yuan Wu, Ling-yue Dong, Wei An

“…Conclusions: The insufficient ALR crotonylation might be a crucial mechanism contributing to the pathogenesis of MASLD. …”
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Exponential Global Health Hazards of Pharmaceutical Pollution and Its Preventive Measures: A Comprehensive Review by Renu Tushir, Sanjita Das, Ajesh Chauhan, Saurav Gurjar, Lakshay Bhanwala, Sneha Patnaik, Anushka Jain

“…Results: In the present study, an effort was made to pinnacle sources, categories, and information regarding various drugs and regulatory bodies across the globe to control these functions.  To overcome the pharmaceutical pollution issues, functions, categories of wastes, and strategies to resolve were elaborated. …”
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Player-avatar bonds and gaming benefits and risks: Assessing self-discrepancy theory against a broader range of character and play experiences by Jeffrey G. Snodgrass, Seth I. Sagstetter, Julia R. Branstrator, Alessandro Giardina, Michael G. Lacy, Aaunterria Treil Bollinger-Deters, Chaz L. Callendar, Katya Xinyi Zhao, H.J. François Dengah II, Joël Billieux

“…Nor has self-discrepancy research explored how avatar experiences might function in forms of play with positive and negative aspects, e.g., in situations where challenge, suffering, and repeated failure are preconditions for eventual feelings of accomplishment. …”
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The Prognostic Value and Potential Mechanism of Tumor-Nutrition-Inflammation Index and Genes in Patients with Advanced Lung Cancer by Huan Wang, Yuting Shi, Yueli Shi, Mengqing Cao, Long Zhang, Yuan Wu, Yun Xu, Kai Wang, Xianwu Weng

“…Conclusion. TNI might be an analytical tool which was practical and precise for survival prediction of patients with advanced LC. …”
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Ultraviolet laser induced periodic surface structures positively influence osteogenic activity on titanium alloys by Luiz Schweitzer, Luiz Schweitzer, Janosch Schoon, Niklas Bläß, Katrin Huesker, Janine V. Neufend, Nikolai Siemens, Sander Bekeschus, Sander Bekeschus, Rabea Schlüter, Peter Schneider, Eckart Uhlmann, Eckart Uhlmann, Georgi Wassilew, Frank Schulze

“…Background/ObjectiveEndoprostheses might fail due to complications such as implant loosening or periprosthetic infections. …”
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Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…We hypothesized that the presence of a secondary system for L-met production conferred by MetAB in W7 but not IA3902 might explain the difference in both chicken colonization and L-met availability. …”
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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits by Yiying Hu, Alexander Hruscha, Chenchen Pan, Martina Schifferer, Michael K. Schmidt, Brigitte Nuscher, Martin Giera, Sarantos Kostidis, Özge Burhan, Frauke van Bebber, Dieter Edbauer, Thomas Arzberger, Christian Haass, Bettina Schmid

“…Our results suggest that functional deficits of the hypothalamus, the metabolic regulatory center, might be the primary cause of weight loss in ALS patients. …”
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Taurine Alleviates Pancreatic β‐Cell Senescence by Inhibition of p53 Pathway by Baomin Wang, Ziyan Wang, Yumei Yang, Melody Yuen Man Ho, Runyue Yang, Huizi Yang, Siyi Liu, Huige Lin, Kenneth King Yip Cheng, Xiaomu Li

“…Conclusion Our findings suggest that increasing β‐cell taurine uptake might be a feasible approach to preserve β‐cell function by targeting the p53‐dependent senescent response.…”
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Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial by Hiroyuki Ase, Kaoru Honaga, Mami Tani, Tomokazu Takakura, Futoshi Wada, Yuhei Murakami, Reina Isayama, Akira Tanuma, Toshiyuki Fujiwara

“…Conclusion Compared to a conventional home program, combining a task-oriented virtual reality home program and outpatient occupational therapy might lead to greater improvements in upper extremity function and the frequency of use of the paretic hand. …”
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LEPREL1 Expression in Human Hepatocellular Carcinoma and Its Suppressor Role on Cell Proliferation by Jianguo Wang, Xiao Xu, Zhikun Liu, Xuyong Wei, Runzhou Zhuang, Di Lu, Lin Zhou, Haiyang Xie, Shusen Zheng

“…Clinical parameters analysis suggested that LEPREL1 was an independent factor in the development of HCC. The biology function experiments showed that LEPREL1 might serve as a potential tumor suppressor gene by inhibiting the HCC cell proliferation.…”
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N6-methyladenosine modification of MEF2A weakens cetuximab sensitivity in colorectal cancer via PD-L1/SOX12 axis by Cao Gao, Jiajia He, Jiemin Zhao, Xuefeng Ni, Yanjie Xu

“…In conclusion, m6A-modified MEF2A alleviated cetuximab sensitivity in CRC via PD-L1/SOX12 mRNA axis, indicating that MEF2A might function as a promising therapeutic target against cetuximab-resistant CRC.…”
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Relationship between reduced serum ceruloplasmin levels and executive dysfunction in hospitalized schizophrenia patients by Dan Kuang, Hongkai Wei, Wei Qin

“…ObjectiveExecutive dysfunction is a widespread and complex manifestation in schizophrenia, significantly impairing patients’ cognitive and functional outcomes. Despite extensive research, specific biomarkers associated with this dysfunction remain unidentified. …”
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