Mouse repeated electroconvulsive seizure (ECS) does not reverse social stress effects but does induce behavioral and hippocampal changes relevant to electroconvulsive therapy (ECT)... by Erin M van Buel, Hannes Sigrist, Erich Seifritz, Lianne Fikse, Fokko J Bosker, Robert A Schoevers, Hans C Klein, Christopher R Pryce, Ulrich Lm Eisel

“…As such, the current model does not provide insights into the mechanism of ECT antidepressant function but does provide evidence for pathophysiological mechanisms that might contribute to important ECT side-effects.…”
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Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway by Hei-Yin Tam, Jiaxing Liu, Tsz-Ching Yiu, Adrian On-Wah Leung, Chang Li, Shen Gu, Owen Rennert, Boxian Huang, Hoi-Hung Cheung

“…Conclusions These results suggested that targeting the SHIP/AKT signaling pathway is beneficial to WRN-deficient stem cells and fibroblasts, which might be applied for improving the trophic function of MSC in, for instance, promoting angiogenesis.…”
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Radix Rehmanniae and Corni Fructus against Diabetic Nephropathy via AGE-RAGE Signaling Pathway by Jing Chen, Yuping Chen, Anmei Shu, Jinfu Lu, Qiu Du, Yuwei Yang, Zhiyang Lv, Huiqin Xu

“…The administratiom of RC might remit the DM-induced renal damage through the AGE-RAGE signaling pathway to improve metabolic parameters and protect renal structure and function.…”
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Duration Mismatch Negativity in Adults With Autism Spectrum Disorder Versus Healthy Controls by Sato A, Itagaki S, Ohnishi T, Osakabe Y, Hoshino H, Kanno K, Suzutani K, Wada T, Miura I, Yabe H

“…After excluding patients with a low intelligence quotient, those using central nervous system stimulants, and those with excessive alcohol consumption, we conducted an auditory oddball task to measure the d-MMN.Results: Compared with HCs, the patients with ASD showed significantly shorter d-MMN latencies for Fz and Cz.Conclusion: The present findings suggest that the automatic cognitive function indicated by MMN amplitude might be improved by growth. …”
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Magnetohyrodynamic Turbulence in a Spherical Shell: Galerkin Models, Boundary Conditions, and the Dynamo Problem by John V. Shebalin

“…Galerkin methods use orthogonal function expansions to represent dynamical fields, with each orthogonal function individually satisfying imposed boundary conditions. …”
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Upregulated Expression of Runt-related Transcription Factor 3 and Interferon Regulatory Factor 4 Genes in Patients With Ankylosing Spondylitis by Sara Assadiasl, Narjes Soleimanifar, Abdolrahman Rostamian, Maryam Sadr, Hanieh Mojtahedi, Maryam Ahmadi, Abeda Mazari, Mohammad Hossein Nicknam

“…In addition, there was a direct correlation between IRF4 gene expression and bath ankylosing spondylitis global score (BAS-G) (correlation coefficient=0.38, P=0.04) Conclusion: Gene expression of RUNX3 and IRF4 transcription factors involved in T cells’ differentiation and function was increased in AS. These findings might have prognostic and therapeutic value.…”
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Regenerative Strategies in Dentistry: Harnessing Stem Cells, Biomaterials and Bioactive Materials for Tissue Repair by Vidhya Rekha Umapathy, Prabhu Manickam Natarajan, Bhuminathan Swamikannu

“…However, these methods do not enable the natural function and aesthetics of the teeth to be maintained in the long term. …”
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Cerebellar Purkinje Cells and GABA Neurotransmission in the Diabetic Rodent Models: A Systematic Review by Viskasari P Kalanjati, Rayhan B Mahdi, Dwi Martha Nur Aditya

“… • Impaired motor and cognitive functions were observed related to cerebellar Purkinje cell damage in a diabetic rat model.   …”
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Long‐term p110α PI3K inactivation exerts a beneficial effect on metabolism by Lazaros C. Foukas, Benoit Bilanges, Lucia Bettedi, Wayne Pearce, Khaled Ali, Sara Sancho, Dominic J. Withers, Bart Vanhaesebroeck

“…In contrast, loss‐of‐function mutations in p110α impair insulin signalling and cause insulin resistance, inducing a pre‐diabetic state. …”
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Comprehensive multi-omics pan-cancer analysis revealed EGFLAM as a potential prognostic and immune infiltration-associated biomarker by Jian Yang, Wenqian Xu, Shengyu Wang, Zhu Yu, Yue Feng, Da Li, Junqiang Chen

“…Abstract EGFLAM is a versatile protein widely expressed in multiple human tissues, yet its function in pan-cancer is not fully understood. To investigate the molecular function of EGFLAM, a comprehensive pan-cancer analysis was carried out using several public databases and bioinformatics tools. …”
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Anaemia of Chronic Diseases: Liver Cirrhosis as a Prototype by Ibrahim Kalle Kwaifa* and Cecilia Stephen

“…Excessive damaged to the liver might to its inability to function normally. Liver cirrhosis associated with ACD can be prevented through several ways, including; the liver would be kept in excellent condition, lifestyle modifications, that includes frequent check-ups, moderate to moderate alcohol consumption, physical activity, and a healthy diet. …”
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Approach to investigation and management of proteinuria in pregnancy by Isabela Bertoni, Sion Williams

“…Clinicians should establish the level of excretory kidney function and the presence or absence of proteinuria at booking/diagnosis. …”
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An industrial safety automation system using GSM technology by Prachuryya Subash Das, Monisha Pathak Pathak

“…The proposed system will be modelled to perform on both automatic and manual controls where the former will ensure security even when employees/workers might be absent inside an industry. Further the auto-mode would ensure relay drivers, relays, and alarm along with additional motor drivers that would systematically function coolers, emergency vents, and other emergency devices connected with the loads.…”
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Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm by E. V. Makarova, S. M. Minin, V. I. Chernov, E. V. Krivoshchekov, Yu. B. Lishmanov

“…Single-photon emission computed tomography with 99mTc-MYOVLEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-rev ascularization LF function recovery. …”
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Al-Hajj Umar Taal or El-Hajj Malik El-Shabazz (Malcolm X)? Case Studies on Islam and Interreligious Pan-African Unity by Jimmy Earl Butts

“…A comparison between the function of Islam in the lives of Al-Hajj Umar Taal and El-Hajj Malik El-Shabazz (Malcolm X) suggests that Shabazz’s example of translating his Islamic obligations into the secular philosophy of Pan-Africanism reflects more promise toward the interest of interreligious Pan-African unity. …”
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Enrichment of rare CFTR variants in Finnish patients with congenital chloride diarrhea. by Satu Wedenoja, Jarmo Ritari, Jukka Partanen, Juha Kere, Kaija-Leena Kolho

“…<h4>Objective</h4>The autosomal recessive disease congenital chloride diarrhea (CLD), caused by loss-of-function mutations in the solute carrier family 26 member 3 (SLC26A3) gene, shows association with inflammatory bowel disease (IBD). …”
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Computer-based cognitive interventions in acquired brain injury: A systematic review and meta-analysis of randomized controlled trials. by Rodrigo Fernández López, Adoración Antolí

“…<h4>Introduction</h4>Acquired brain injury (ABI) leads to cognitive deficits in a great variety of cognitive functions. Interventions aimed at reducing such deficits include the use of computer-based cognitive interventions. …”
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The post-Cartesian dilemma: Reuniting the mind and body through psychoneuroimmunology by Jeanette M. Bennett

“…While today, it might seem absurd to hear anyone claim that stress does not alter all aspects of the human experience, including behavioral, cognitive, affective, and physiological processes. …”
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Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. by Susana Pascoal, Joana Esteves de Lima, Jonathan D Leslie, Simon M Hughes, Leonor Saúde

“…<h4>Background</h4>Accurate regulation of Notch signalling is central for developmental processes in a variety of tissues, but its function in pectoral fin development in zebrafish is still unknown.…”
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El gobierno de la archidiócesis de Zaragoza en el pontificado de Juan Soldevila (1902-1923) / The government of the archdiocese of Saragossa in the pontificate of Juan Soldevila (1... by Santiago Casas Rabasa

“…The priestly condition seemed essential to him in order to be more open and available to whatever God might ask of him in the future. Perhaps not from a theoretical point of view, but from a practical one, in Saragossa he had his first knowledge of how a diocese was administered and how the power of government was exercised within the Church. …”
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