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981
Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice.
Published 2008-09-01“…However, it is not clear whether Tex19.1 has an essential function in germ cells or pluripotent stem cells, or what that function might be. …”
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982
D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion
Published 2018-01-01“…Our data uncovered a previously unrecognized function of D-mannose to regulate the immunomodulatory function of PDLSCs and that IL-6 might play a key role in this process. …”
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983
In vitro Interaction of HSV-1 ORF P with Both Thymidine Kinase (TK) and an Unidentified Cellular Protein
Published 2006-03-01“…ORF P is also deleted in ICP34.5 negative mutants and to date, no definite function is attributed to it. An approach to analyze the function of a viral gene such as ORF P is to determine if this gene interacts with any of the cellular and viral proteins both in vitro and in vivo. …”
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984
CyTOF as a suitable tool for stratification and monitoring of cancer patients
Published 2025-07-01“…Since mass cytometry is a powerful multiplex approach to decipher tumor intrinsic and tumor extrinsic effects of tumor immunotherapies, this review summarizes the use of this technology for determination of the frequency and functional status of immune cell populations within the tumor and in the blood leading to the identification of intratumoral/peripheral immune signatures that might serve as biomarkers (i) for treatment response and/or failure, (ii) for the stratification of tumor patients or (iii) for the identification of novel therapeutic targets.…”
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985
Entropy and Multifractality in Relativistic Ion-Ion Collisions
Published 2018-01-01“…The findings reveal that Rényi’s order q information entropy could be another way to investigate the fluctuations in multiplicity distributions in terms of spectral function f(α), which has been argued to be a convenient function for comparison sake not only among different experiments but also between the data and theoretical models.…”
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986
Large θ angle in two-dimensional large N CP N − 1 $$ {\mathbbm{CP}}^{N-1} $$ model
Published 2025-05-01“…However, when θ/N is of order O 1 $$ \mathcal{O}(1) $$ , we encounter a problem about saddle points that would give larger contributions to the partition function than the true vacuum. We discuss why it might not be straightforward to resolve this problem.…”
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987
Management of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)
Published 2021-12-01“…Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a common complication in CKD, which occurs early in the disease, and progresses as kidney function deteriorates. With declining kidney function, mineral homeostasis becomes progressively dysregulated, including alterations in several parameters such as calcium, phosphate, intact parathyroid hormone (iPTH). …”
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988
A New Way to Treat Central Nervous System Dysfunction Caused by Musculoskeletal Injuries Using Transcranial Direct Current Stimulation: A Narrative Review
Published 2025-01-01“…These deficits, controlled in part by the central nervous system (CNS), might be alleviated with an appropriate adjuvant treatment. …”
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989
Performance Analysis of Diabetes Detection Using Machine Learning Classifiers
Published 2024-10-01“…Three types of machine learning classifiers are used: Tree-based, Function-based, and Rule-based. Results have shown that Stochastic Gradient Descent (function), Logistic Regression (function), JRip (rules) and Random Forests (trees) are among the top performing classifiers. …”
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990
CDCA2 Promotes HCC Cells Development via AKT–mTOR Pathway
Published 2022-01-01“…Methods. Gain- and loss-of-function experiments were conducted to determine the biological function of CDCA2 in HCC cells. …”
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991
Effect of Corrosion Damage on the Performance Level of a 25-Year-Old Reinforced Concrete Building
Published 2012-01-01“…Most of the structural problems observed under the impact of either earthquakes or service loads might occur due to corrosion. Therefore, prediction of the remaining service life of a corroding RC structure plays an important role to prevent serious premature damage. …”
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992
Yes-associated protein 65 (YAP) expands neural progenitors and regulates Pax3 expression in the neural plate border zone.
Published 2011-01-01“…Yes-associated protein 65 (YAP) contains multiple protein-protein interaction domains and functions as both a transcriptional co-activator and as a scaffolding protein. …”
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993
Slowing down in PNP: relationship of joint velocities in an arm-movement test and the fast TUG test
Published 2025-08-01“…Abstract Polyneuropathy (PNP) is a prevalent neurological disorder that affects both upper and lower limbs leading to a decline in motor and sensory nerve function and consequently, to movement impairments. …”
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994
Chrysanthemum indicum Flavonoid Extract on the Oxidative Stress Resistance of Caenorhabditis elegans
Published 2025-06-01Get full text
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995
Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing
Published 2013-01-01“…Analysis of the response profiles of cardiopulmonary responses at submaximal exercise and recovery, however, might show abnormal physiologic functioning which would not be otherwise unraveled. …”
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996
Symmetric dimethylarginine as a biomarker of renal impairment after a decade of follow-up
Published 2025-08-01“…These findings suggest that SDMA might predict future deterioration of renal function. …”
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997
Russian Phraseological Units with Zoonyms: Aspects of Comprehensive Description (A Case Study of Expressions Featuring Zoonym ‘volk’ [Wolf]
Published 2024-11-01“…It is demonstrated that these phraseological units characterize individuals based on their personality traits and behaviors, express varying degrees of negative emotions, and exhibit diverse stylistic nuances and grammatical structures. The functioning of these idioms is influenced by their composition (the expression featuring the zoonym ‘travlenyy volk’ [tricked wolf] is rarely encountered and primarily appears in literary texts), their figurative components (the expression ‘morskoy volk’ [sea wolf] is the most frequent, losing its association with predation and reflecting a stereotypical image of a sailor), lexical meanings (in literary texts, nominal phraseological units often serve a predicative function when characterizing individuals), and stylistic properties (the expressiveness and colloquial nature of the unit ‘khot' volkom voy’ [you might as well howl like a wolf] predominantly determine its use in literary texts within character dialogue).…”
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998
Increased Cell Fusion in Cerebral Cortex May Contribute to Poststroke Regeneration
Published 2013-01-01“…The appearance of additional neuronal nuclei increases the functional outcome of the population of neurons. Participation of a certain number of binuclear cells in neuronal function might compensate for a functional deficit that arises from the death of a subset of neurons. …”
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999
Heterogeneidade nos deficits de percepção do movimento em perturbações do desenvolvimento: o caso do Autismo e da Síndrome de Williams
Published 2009-01-01“…Moreover, a different pattern of low level motion detection deficits might underlie each of these developmental disorders. …”
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1000
Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review
Published 2020-01-01“…However, neurocognitive complications following ventricular neuroendoscopic procedures may occur leading mostly to amnesia, which might have a grave effect on the patient’s quality of life. …”
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