Urinary apolipoprotein A4 as a biomarker for renal allograft injury in kidney transplant recipients. by Youn Kyung Kee, Dong Ho Shin, Jieun Oh, Ji Young Park, Dong Hyun Kim, Kyungjai Ko, Samuel Lee, Hee Jung Jeon

“…ROC curve analysis revealed the area under the curve (AUC) of 0.834 (95% CI 0.722-0.945, P < 0.001) for urinary ApoA-IV levels in predicting rapid renal function decline. Our results suggest that urinary ApoA-IV levels might be a potential biomarker for renal allograft function and could be used as a predictor for rapid renal function decline in KTRs.…”
Get full text

The Guardian of Dreams: The Neglected Relationship Between Sleep and Psychoanalysis by Giuseppe Barbato

“…He was also not interested in sleep, which was considered a problem of physiology; however, sleep appears to have a central role in his model, since dreaming is considered the guardian of sleep. The function of dreaming, according to Freud, is to protect sleep from disruption, with the dream working to avoid repressed stimuli interrupting the “biological” function of sleep. …”
Get full text

Revisiting anesthesia-induced preconditioning for neuroprotection in the aging brain: a narrative review by Tao Zhang, Woosuk Chung, Beverley A. Orser

“…Although further research is needed to determine the impact of physical prehabilitation on mitochondrial function and anesthetic preconditioning, incorporating physical prehabilitation into perioperative care might enhance neurological outcomes for older patients undergoing surgery.…”
Get full text

Postpartum depression and thyroid dysfunction– should pregnant women be screened for thyroid disorders? by Anca A. Simionescu, Erika Marin

“…The relationship between thyroid dysfunction and postpartum depression has been investigated for quite some time now, but no consensus has been reached regarding the need for screening for thyroid function during pregnancy. This paper aims to investigate whether thyroid hormone screening in pregnancy might contribute to the diagnosis of postpartum depression. …”
Get full text

Fasting the mitochondria to prevent neurodegeneration: the role of ceramides by Luis Armando Valenzuela-Ahumada, Octavio Fabián Mercado-Gómez, Rubi Viveros-Contreras, Rosalinda Guevara-Guzmán, Alberto Camacho-Morales

“…Diet-derived ceramides species might target and disrupt mitochondria function leading to defective energy balance and neurodegeneration. …”
Get full text

Multi-Beam Focusing and Deflecting Characteristics of Liquid Crystal Optical Phased Array by Xue Xu, Lin Xu, Xitong Liang, Jun Dai

“…On the other hand, multi-beam fan-out capability alone may not be sufficient in some application scenarios. The additional function of focusing might bring some new advantages. …”
Get full text

The fitness cost and benefit of phase‐separated protein deposits by Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu

“…However, protein deposits can also function as membrane‐less compartments for many cellular processes. …”
Get full text

Spatial Aspect of Michel Foucault’s Biopolitical Conception by N. N. Orleanskiy

“…According to Michel Foucault’s biopolitical conception, space loses its previous function as an attribute of power and might and acquires the new one — an encouragement to a human. …”
Get full text

Obesity as the Sequel of Childhood Stunting: Ghrelin and GHSR Gene Polymorphism Explained by Harry Freitag Luglio Muhammad

“…Stunting during childhood might affect brain development and impair development cognitive function. …”
Get full text

Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? by Mijna Hadders-Algra

“…Probably the major sources of origin of simple MND are genetic constitution and stress during early life. Simple MND might reflect the lower tail of the normal distribution of the quality of non-pathological brain function. …”
Get full text

When the transmission of culture is child's play. by Mark Nielsen, Jessica Cucchiaro, Jumana Mohamedally

“…When the adult modeled the actions in a playful manner they were retained down to the third child at higher rates than when the adult seeded them in a functionally oriented way.<h4>Conclusions</h4>Our results draw attention to the possibility that play might serve a critical function in the transmission of human culture by providing a mechanism for arbitrary ideas to spread between children.…”
Get full text

Obesity as the Sequel of Childhood Stunting: Ghrelin and GHSR Gene Polymorphism Explained by Harry Freitag Luglio Muhammad

“…Stunting during childhood might affect brain development and impair development cognitive function. …”
Get full text

The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing. by Shin Yee Hong, Li Theng Ng, Li Fang Ng, Takao Inoue, Nicholas S Tolwinski, Thilo Hagen, Jan Gruber

“…We posited that organismal ageing might be accompanied by an accumulation of acylated proteins, especially in mitochondria, and that this might compromise mitochondrial function and contribute to ageing. …”
Get full text

Self-Management for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zugui Wu, Rui Zhou, Yue Zhu, Ziquan Zeng, Zixuan Ye, Zhenbang Wang, Wengang Liu, Xuemeng Xu

“…The meta-analysis results showed that self-management might help improve the pain, knee function, stiffness, ASE, mental health, and quality of life in patients with KOA. …”
Get full text

Mutational analysis of the yeast TRAPP subunit Trs20p identifies roles in endocytic recycling and sporulation. by Hichem Mahfouz, Antonella Ragnini-Wilson, Rossella Venditti, Maria Antonietta De Matteis, Cathal Wilson

“…The role of Trs20p, which is essential for viability and a component of all three complexes, and how it might function within each TRAPP complex, has not been clarified to date. …”
Get full text

Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK. by Mike Bührmann, Bianca M Wiedemann, Matthias P Müller, Julia Hardick, Maria Ecke, Daniel Rauh

“…Small organic molecules that target these less conserved regions might serve as tools for chemical biology research and to probe alternative strategies in targeting protein kinases in disease settings. …”
Get full text

An Adaptive Learning Rate for RBFNN Using Time-Domain Feedback Analysis by Syed Saad Azhar Ali, Muhammad Moinuddin, Kamran Raza, Syed Hasan Adil

“…Radial basis function neural networks are used in a variety of applications such as pattern recognition, nonlinear identification, control and time series prediction. …”
Get full text

A bidirectional relationship between sleep and oxidative stress in Drosophila. by Vanessa M Hill, Reed M O'Connor, Gunter B Sissoko, Ifeoma S Irobunda, Stephen Leong, Julie C Canman, Nicholas Stavropoulos, Mimi Shirasu-Hiza

“…Although sleep appears to be broadly conserved in animals, the physiological functions of sleep remain unclear. In this study, we sought to identify a physiological defect common to a diverse group of short-sleeping Drosophila mutants, which might provide insight into the function and regulation of sleep. …”
Get full text

USP17 is upregulated in osteosarcoma and promotes cell proliferation, metastasis, and epithelial–mesenchymal transition through stabilizing SMAD4 by Chenyang Song, Wenge Liu, Jiandong Li

“…USP17 is upregulated in several cancers, indicating that USP17 might play essential functions in tumor development. …”
Get full text

The length and strength of compartmental interactions are modulated by condensin II activity. by Randi Isenhart, Son C Nguyen, Leah Rosin, Weihuan Cao, Patrick Walsh, Haris Muzaffar, Christopher E Ellison, Eric F Joyce

“…The spatial organization of the genome is crucial for its function and integrity. Although the ring-like SMC complex condensin II has a well-documented role in organizing mitotic chromosomes, its function in interphase chromatin structure has remained more enigmatic. …”
Get full text