Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. by Daniel Krell, Mawuelikem Assoku, Malcolm Galloway, Paul Mulholland, Ian Tomlinson, Chiara Bardella

“…Alternatively, both loss of IDH function and 2HG accumulation might be required for tumourigenesis, and only IDH1 and IDH2 mutations have these dual effects.…”
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Personal Ornaments and Burial Rites in Prehistory by Selena Vitezović

“…However, personal ornaments might have had a much wider symbolic meaning. In this paper, we will look at the possibilities in terms of the meanings of personal ornaments from prehistoric contexts – beside markings of identity and status of the deceased, they might also have represented a gift to the deceased, gift to divinities, they might have had an apotropaic and a prophylactic function, for both the deceased and the participants in the burial ritual, and they might also have had an emotional meaning.…”
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The Association of Olfactory Dysfunction, Frailty, and Mortality Is Mediated by Inflammation: Results from the InCHIANTI Study by Alice Laudisio, Luca Navarini, Domenico Paolo Emanuele Margiotta, Davide Onofrio Fontana, Irene Chiarella, Daniele Spitaleri, Stefania Bandinelli, Antonella Gemma, Luigi Ferrucci, Raffaele Antonelli Incalzi

“…Impairment of olfactory function might represent a marker of frailty, prefrailty, and consequently reduced survival in an advanced age. …”
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Arsenic Primes Human Bone Marrow CD34+ Cells for Erythroid Differentiation by Yuanyuan Zhang, Shasha Wang, Chunyan Chen, Xiao Wu, Qunye Zhang, Fan Jiang

“…We discovered that arsenic trioxide enhanced the erythroid colony forming activity, which was accompanied by a decrease in the granulomonocytic differentiation function. Moreover, in erythroleukemic K562 cells, we showed that arsenic trioxide inhibited erythrocyte maturation, suggesting that arsenic might have biphasic effects on erythropoiesis. …”
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Identification and expression analysis of NUDIX gene family in Rosa chinensis ‘Old Blush’ by FANG Huiyi, LIANG Yuwei, LI Xinyuan, Sun Fuhui, BI Bo, ZHANG Liangsheng

“…The NUDIX gene family might play an important role in physiological processes such as secondary metabolism, growth and development, and stress response in leaf of Rosa chinensis ‘Old Blush’, which provides a theoretical basis for further research on the function of NUDIX genes in Rosa chinensis ‘Old Blush’.…”
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Inferring the temporal order of cancer gene mutations in individual tumor samples. by Jun Guo, Hanliang Guo, Zhanyi Wang

“…The initial mutations appear to be dedicated to acquiring the function of evading apoptosis, and some order constraints might reflect potential regularities. …”
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Expression of DISC1-interactome members correlates with cognitive phenotypes related to schizophrenia. by Antonio Rampino, Rosie May Walker, Helen Scott Torrance, Susan Maguire Anderson, Leonardo Fazio, Annabella Di Giorgio, Paolo Taurisano, Barbara Gelao, Raffaella Romano, Rita Masellis, Gianluca Ursini, Grazia Caforio, Giuseppe Blasi, J Kirsty Millar, David John Porteous, Pippa Ann Thomson, Alessandro Bertolino, Kathryn Louise Evans

“…Dysregulated expression of DISC1-interactome genes might, therefore, contribute to schizophrenia susceptibility via disruption of molecular systems required for normal cognitive function. …”
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Figurative Language Expressions in English Language Selected Videos Posted in TikTok Application by Succia Putri Nabila, Azwandi, Iis Sujarwati

“…Meanwhile there are five functions of figurative language discovered through the videos consist of referential function, expressive function, conative function, poetic function and phatic function. …”
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Hepatic Regeneration: If it Ain’t Broke, Don’t Fix it by GY Minuk

“…Since both hepatic regeneration and metabolic function require energy from high-energy nucleotide triphosphates, especially adenosine triphosphate (ATP), a reasonable strategy might be to augment energy delivery and ATP production. …”
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L’odeur de l’axé by Arnaud Halloy

“…Curiously, such phenomenological blatancy has never caught much interest among Afro-Brazilianists. It might be ethnographically noticed here and there, but there are very few attempts, if any, of theorizing their potential ritual function. …”
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Recent advances in recurrent urinary tract infection from pathogenesis and biomarkers to prevention by Jia-Fong Jhang, Hann-Chorng Kuo

“…Bacterial survival in the urinary bladder after antibiotic treatment and progression to form intracellular bacterial communities might be the most important bacterial factors. In host defense deficiency, a defect in pathogen recognition and urothelial barrier function impairment play the most important roles. …”
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Bacterial Diversity and Community Composition in the Pyloric Ceca of Acanthaster solaris in the Xisha Islands by Yu Jiaoyang, Yu Xiaopeng, Yu Kefu, Ma Yuling

“…The results of bacterial function predict that their genome function was mainly focused on metabolism. …”
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Advances in Our Understanding of “Resistance” to Antiplatelet Agents for Prevention of Ischemic Stroke by Philip B. Gorelick, Muhammad U. Farooq

“…Debates have raged over the years about the application of platelet function tests in clinical practice. We conclude that platelet function testing is not indicated in routine clinical practice. …”
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Postural Muscle Dyscoordination in Children With Cerebral Palsy by Jolanda C. van der Heide, Mijna Hadders-Algra

“…This might imply that both stereotypies might be regarded as functional strategies to compensate for the dysfunctional capacity to modulate subtly postural activity.…”
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Changes in Distortion Product Otoacoustic Emission Caused by Contralateral Broadband Noise by Edward OZIMEK, Andrzej WICHER

“…The mean suppression level of the component of the frequency $f_{DP} = 2f_1 − f_2$ might be approximated by a linearly decreasing function of the $f_2$ frequency of primary tones. …”
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Evidence for developmental programming of cerebral laterality in humans. by Alexander Jones, Clive Osmond, Keith M Godfrey, David I W Phillips

“…Environmental pressures on the fetus, resulting from variations in placental function and maternal nutrition, health and stress might alter neurodevelopment, promoting the development of some brain regions over others. …”
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Potential Moderators of Physical Activity on Brain Health by Regina L. Leckie, Andrea M. Weinstein, Jennifer C. Hodzic, Kirk I. Erickson

“…There are a growing number of studies indicating that physical activity might mitigate the genetic risks for disease and brain dysfunction and that the combination of greater amounts of DHA intake with physical activity might promote better brain function than either treatment alone. …”
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Computational Analysis of Gly482Ser Single-Nucleotide Polymorphism in PPARGC1A Gene Associated with CAD, NAFLD, T2DM, Obesity, Hypertension, and Metabolic Diseases by Somayye Taghvaei, Leila Saremi, Sepideh Babaniamansour

“…Due to this single-nucleotide polymorphism in PPARGC1A, it became more rigid and might disarray the structural conformation and catalytic function of the protein and might also induce type 2 diabetes mellitus (T2DM), coronary artery disease (CAD), and nonalcoholic fatty liver disease (NAFLD). …”
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Mitochondria and PGC-1α in Aging and Age-Associated Diseases by Tina Wenz

“…This paper discusses how mitochondrial function and PGC-1α are affected in age-associated diseases and how modulation of PGC-1α might offer a therapeutic potential for age-related pathology.…”
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Arterial hypertension therapy effectiveness in smokers by D. V. Nebieridze, F. A. Papova, N. S. Ivanishina, A. S. Safaryan, N. L. Vinnitskaya, A. Meliya

“…In such patients, medications improving endothelial function might be more effective. At the same time, more evidence is needed to compare various antihypertensive classes’ effectiveness in smokers.…”
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