Association of C1QTNF6 gene polymorphism with risk and clinical features of type 1 diabetes in Chinese: implications for ZnT8A and beta-cell function by Jinhan Liu, Ying Xia, Zhiguo Xie, Xia Li, Gan Huang, Jingyi Hu, Zhiguang Zhou

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Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation by Ming Zhao, Xiwen Xiong, Kaiqun Ren, Bing Xu, Meng Cheng, Chinmayi Sahu, Kaichun Wu, Yongzhan Nie, Zan Huang, Richard S Blumberg, Xiaonan Han, Hai‐Bin Ruan

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LncRNA MIR99AHG serves as a diagnostic marker for early lung cancer and regulates cancer cell growth and metastasis via miR-194-5p by Wenhui Li, Wenhan Li, Zhen Xu

“…However, the concurrent overexpression of MIR99AHG and miR-194-5p appeared to negate this inhibitory effect. Conclusion MIR99AHG might as a supplementary diagnosis tool for early NSCLC. …”
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Stem cell derived extracellular vesicles therapy for perinatal brain injury: A systematic review & meta-analysis of preclinical studies and a potential path to clinic by Xiaolin Guo, Tingting Peng, Mengru Zhong, Simian Cai, Lu He, Kaishou Xu

“…Sensitivity analysis and subgroup analysis did not identify the source of heterogeneity. Conclusion: SC-EVs might improve cognitive and motor functions, as well as brain microstructure, by exerting anti-apoptotic and anti-neuroinflammatory effects. …”
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N-acetylcysteine in Kidney Disease: Molecular Mechanisms, Pharmacokinetics, and Clinical Effectiveness by Estefani Y. Hernández-Cruz, Omar E. Aparicio-Trejo, Fadi A. Hammami, Daniel Bar-Shalom, Martin Tepel, Jose Pedraza-Chaverri, Alexandra Scholze

“…Delayed administration of NAC might interfere with endogenous repair mechanisms. …”
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Vector Decimation Harmonic Mean-Based Algorithm for Online Acoustic Feedback Active Noise Control by Suman Turpati, Ajay Roy, Tathababu Addepalli, Mohammed Alkahtani, Abdullatif Hakami, Ahmad Faiz Minai, Abdallah Hammad

“…However, the feedback path could change over time, so we might have to make modifications often while the ANC system is online. …”
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hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats by Yu Tang, Yaru Si, Chengen Liu, Cui Li, Li Qu, Ying Liu, Qiang Fu, Qianqian Luo

“…As a broad-spectrum chemotherapy drug in clinic, the damage of cisplatin (CDDP) to female reproductive function cannot be ignored. At present, the study of CDDP damage to the uterus is not sufficient, and the exact mechanism needs to be further explored. …”
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Acute effect of a multi-ingredient pre-workout supplement on pacing and kinetic expression during shorter and longer bouts of high intensity functional training by Gerald T. Mangine, Christopher Staples, James W. Henley, Ashley Hines, Kristyn C. McGeehan, Wysmark Chaves, Wil King, Tiffany A. Esmat, John R. McLester, Jacob L. Grazer

“…Background High-intensity functional training (HIFT) varies daily workout programming, and trainees are often tasked with completing “as many repetitions as possible” (AMRAP) within a set time. …”
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Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments. by Xiangdong Ye, Xiaolin Deng, Huanhuan Gao, Shuwen Chen, Li Ding, Fang Sun, Chenhu Qin, Hongyi Luo, Wen Zhu, Xudong Luo, Zongyun Chen

“…Structural modelling of nine schistosoma-derived full-length secreted proteins suggested that the C-terminal non-Kunitz-domain fragments might play important roles in modulating the Kunitz-domain functions by steric hindrance effect and transmembrane helix structure. …”
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Alterations in tidal volume over recording time during pulmonary function testing by barometric whole-body plethysmography in client-owned cats: a multicenter retrospective investi... by Wei-Tao Chang, Laín García-Guasch, Hannah Gareis, Bianka Schulz, Yoshiki Yamaya, Pei-Ying Lo, Chin-Hao Chang, Hui-Wen Chen, Chung-Hui Lin

“…Abstract Background Pulmonary function assessment in small animal clinical patients typically relies on tidal breathing analysis, such as placing cats in a barometric whole-body plethysmography (BWBP) chamber. …”
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Coronavac inactivated vaccine triggers durable, cross-reactive Fc-mediated phagocytosis activities by Lili Wang, Chuang Li, Wanting Li, Liwei Zhao, Tiantian Zhao, Lin Chen, Ming Li, Jing Fan, Jiayan Li, Chao Wu, Yuxin Chen

“…Meanwhile, serum samples from vaccinees, convalescent individuals with wildtype infection, BA.2 and BA.5 breakthrough infection demonstrated differential cross-reactive ADCP and ADNP responses against Omicron subvariants, suggesting the different subvariants of spike antigen exposure might alter the cross-reactivity of Fc effector function. …”
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Mesoporous Silica Particles Functionalized With Poly(Glycidyl Methacrylate) Brushes Cross-linked With Ethanolamine to Potentially Enhance Pollutant Removal From Contaminated Water... by Abeer M. Beagan

“…Furthermore, the kinetics of the adsorption were best described by the pseudosecond-order model, indicating that the rate-determining step might involve chemisorption.…”
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iTRAQ-based quantitative proteomic profiling of the regulatory mechanisms on immune functions and blood lipids in aged mice fed with Lentinula edodes-derived polysaccharides by Xiaofei Xu, Xiaofei Liu, Jin Chen, Jingjing Guan, Donghui Luo

“…Particularly, approximately 16 and 9 DRPs participated in the regulation of immune functions and lipid metabolism, respectively. Furthermore, protein-protein interaction analysis highlighted that cadherin-1, plectin, cadherin-17, Ras GTPase-activating-like protein IQGAP2, and ezrin might be key proteins in response to L2 treatment. …”
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Problem of selection of suitable geosynthetics for the strengthening of subgrade by Elżbieta Szafranko

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Protective Effects of a <i>Brassica nigra</i> Sprout Hydroalcoholic Extract on Lipid Homeostasis, Hepatotoxicity, and Nephrotoxicity in Cyclophosphamide-Induced Toxicity in Rats by Hassan Barakat, Thamer Aljutaily, Raghad I. Alkhurayji, Huda Aljumayi, Khalid S. Alhejji, Sami O. Almutairi

“…The best treatment was BNSE at 500 mg kg⁻¹, as it markedly improved liver function, such as total bilirubin (T.B.), in a dose-dependent manner. …”
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Effects of sumac aqueous extract along with eating and drinking modification on functional dyspepsia symptoms in comparison with omeprazole: An open-label, randomized, controlled c... by Mahdi Saravani, Zahra memariani, Nasser Behnampour, Mohammadreza Seyyedmajidi, fatemeh kolangi

“…Objective: Functional dyspepsia (FD), a common gastrointestinal problem. …”
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Sex-related differential item functioning of the Jenkins Sleep Scale: a cross-sectional study among 77 967 employees in the Finnish public sector by Jussi Vahtera, Mika Kivimäki, Saana Myllyntausta, Jenni Ervasti, Jari P A Arokoski, Mikhail Saltychev, Juhani Juhola

“…However, when using the JSS, the respondents might slightly underestimate the severity of these disturbances. …”
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Functional Alterations of the Basal Ganglia Are Associated with Voluntary Activation of the Core Stabilizing Muscles in Patients with Chronic Low Back Pain: A Cross-Sectional Study by Chanjuan Zhang, Xi Chen, Yi Yin, Dongfeng Xie, Jing Luo, Yinan Ai, Wenfeng Zhan, Hongjun Kan, Shuxian Zhang, Guihua Jiang, Xiquan Hu

“…We obtained structural and resting-state functional magnetic resonance imaging (rs-fMRI) data from 53 patients with CLBP and 67 healthy controls and estimated the alterations in grey matter volume (GMV) and functional and effective connectivity (EC) of regions with altered GMV via whole brain analysis. …”
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Escherichia coli Nissle 1917 Protects Intestinal Barrier Function by Inhibiting NF-κB-Mediated Activation of the MLCK-P-MLC Signaling Pathway by Shihao Guo, Shanwen Chen, Ju Ma, Yongchen Ma, Jing Zhu, Yuanyuan Ma, Yucun Liu, Pengyuan Wang, Yisheng Pan

“…The results indicated that EcN protected the intestinal barrier function in sepsis by ameliorating the altered expression and localization of TJ proteins and inhibiting the NF-κB-mediated activation of the MLCK-P-MLC signaling pathway which might be one of the mechanisms underlying the effect of EcN.…”
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The dose-dependent effect of nesiritide on renal function in patients with acute decompensated heart failure: a systematic review and meta-analysis of randomized controlled trials. by Bo Xiong, Chunbin Wang, Yuanqing Yao, Yuwen Huang, Jie Tan, Yin Cao, Yanke Zou, Jing Huang

“…Overall, compared to control therapies, nesiritide might increase the risk of worsening renal function in patients with acute decompensated heart failure (RR 1.08, 95% CI 1.01-1.15, P = 0.023). …”
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