Comparative efficacy and safety of febuxostat and allopurinol in chronic kidney disease stage 3–5 patients with asymptomatic hyperuricemia: a network meta-analysis by Jiaojiao Chen, Yanyun Zhang, Yinglin Wang, Lu Chen

“…Subgroup analyses revealed enhanced effectiveness of febuxostat at six months of treatment.Conclusions This analysis provides robust evidence that febuxostat might offers greater improvements in kidney function and uric acid levels compared to allopurinol or placebo in asymptomatic hyperuricemia with CKD stage 3–5 patients, without compromising safety. …”
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Dynamic hand and finger load distribution patterns in the first year following surgically treated distal radius fracture by Johannes Karnatz, Christoph Harms, Dagmar-Christiane Fischer, Thomas Mittlmeier

“…Thereby, dynamic hand grip function is objectivated, providing a more detailed insight than with other clinical assessment tools. …”
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Effects of home-based, low-intensity exergaming on cognitive function of individuals with mild cognitive impairment: a study protocol for a randomized controlled trial by Sirintip Kumfu, Somporn Sungkarat, Sirinun Boripantakul, Piangkwan Sa-nguanmoo, Siriporn C. Chattipakorn

“…Discussion The findings of this study might provide valuable insights into an effective and practical intervention program aimed at improving cognitive function of older adults with MCI. …”
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The Impact of Patient Age on Causes of Graft Loss After Renal Transplantation by Susanne Winkler, Min-Jeong Kim, Andrea Fisler, Stefan Farese, Felix Burkhalter, Seraina von Moos, Christian Forster, Caroline Wehmeier, Michael Dickenmann, Stefan Schaub, Stefan Schaub, Stefan Schaub

“…Graft loss causes are strongly age-related. This might have significant implications for clinical study design and patient management.…”
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Is the Hepatitis G Virus a Hidden Menace to Liver Health in Specific Populations? by Hassan Hussein, Muthana Khalil, Yasin Majeed

“…Although it has no clinical significance or impact on liver disease and its future course is uncertain, highly mutated (as in other RNA viruses) might happen, resulting in a severe liver injury.Objective: To evaluate the subclinical impact of hepatitis G virus infection on liver health in high-risk populations through liver function tests (LFTs) analysis.Materials and Methods: Blood samples were taken from 221 people in high-risk groups and chronic liver patients infected with hepatitis B and C viruses. …”
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Can spirometry improve the performance of cardiovascular risk model in high-risk Eastern European countries? by Tatyana Court, Naděžda Čapková, Andrzej Pająk, Abdonas Tamošiūnas, Martin Bobák, Martin Bobák, Hynek Pikhart, Hynek Pikhart

“…AimsImpaired lung function has been strongly associated with cardiovascular disease (CVD) events. …”
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The effect of a session of moderate intensity aerobic exercise on inflammatory factors and flow-mediated dilation in pre-menopausal and post-menopausal women by Arsalan Damirchi, Sanaz Shiravi

“…In addition, vascular dilation after a session of moderate intensity aerobic exercise was significantly (P=0.001) different between premenopausal and postmenopausal women , where, flow mediated dilation increased in premenopausal compared to postmenopausal women.Conclusion: Based on the increased FMD and decreased TNF-α in premenopausal women, in general our findings show that following acute exercise factors associated with endothelial responsiveness are improved in premenopausal women while responses are decreased in postmenopausal womenHowever, lack of differences in interleukins 6 and 8 between premenopausal and postmenopausal women might indicate increased inflammation in premenopausal women, which is a reason for the onset or increases in disorders of endothelial function during menopause.…”
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Impact of a 10-week multimodal stress management and lifestyle modification program on stress response and immune function in Crohn’s disease: a mixed-methods approach using the Tr... by Özlem Öznur, Sandra Utz, Christoph Schlee, Jost Langhorst

“…Differences in the reaction to acute stress might be explained by a significant reduction in perceived (chronic) stress levels in the intervention group compared to baseline (p = .004), whereas there was no change in the control group (p = .472). …”
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Effect of a compound nutrition preparation on wound healing after acute trauma in rats by XIN Wenbin, BAI Qian, NI Xiangmin

“…Conclusion‍　‍Our compound nutrition preparation promotes wound healing in rat model of acute trauma, which might be related to its improving the nutritional status, promoting collagen synthesis, and thus alleviating inflammatory response and enhancing immune function. …”
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Locus coeruleus co‐activation patterns at rest show higher state persistence in patients with dissociative seizures: A Pilot Study by Samantha Weber, Johannes Jungilligens, Selma Aybek, Stoyan Popkirov

“…We found that patients tended to stay in certain locus coeruleus‐dependent brain states instead of switching between them. This might be related to the loss of awareness and disruptions of brain functions (“dissociation”) that patients experience during seizures.…”
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The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes. by Juway Lin, Ya-Jen Chang, Wen-Bin Yang, Alice L Yu, Chi-Huey Wong

“…These results indicated that DH-PS might have potential applications for ameliorating IL-1-induced pathogenic conditions.…”
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Anxiety disorders presenting as gastrointestinal symptoms in children – a scoping review by Anjali Kumar, Pramodh Vallabhaneni

“…Functional gastrointestinal disorders (FGID) and their association with anxiety disorders in children significantly impact a child’s functioning and treatment response. …”
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An Estimation of Different Kinds of Integral Inequalities for a Generalized Class of Godunova–Levin Convex and Preinvex Functions via Pseudo and Standard Order Relations by Zareen A. Khan, Waqar Afzal

“…The connection between generalized convexity and analytic operators is deeply rooted in functional analysis and operator theory. To put the ideas of preinvexity and convexity even closer together, we might state that preinvex functions are extensions of convex functions. …”
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The enigmatic SLC26A6 multifunctional anion transporter: recent advances in structure-function relationship, pathophysiological significance and novel pharmacological inhibitors by Ursula E. Seidler

“…Thirdly, progress has been made in identifying specific inhibitors for SLC26A6. Where might this be of clinical relevance?…”
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A Tailor-Made Legal Suit: The Actual Scope, Power, and Functioning of NAFTA Chapter 11’s Rules and Institutions for the Settlement of Cross-Border Disputes by Iván Farías Pelcastre

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Network localization of regional homogeneity alterations in Parkinson’s disease by Yuanying Song, Hucheng Yang, Hucheng Yang, Siyu Gu, Yingling Zhu, ZhenYu Dai, Pinglei Pan, Xianxian Zhang

“…BackgroundResting-state functional MRI (rs-fMRI) studies using regional homogeneity (ReHo) have identified localized functional changes in Parkinson’s disease (PD), but findings across studies exhibit considerable heterogeneity. …”
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Rab8a restores diverse innate functions in CD11c+CD11b+ dendritic cells from aged mice by Sudhakar Singh, Azeez Tehseen, Surbhi Dahiya, Yuviana J. Singh, Roman Sarkar, Sharvan Sehrawat

“…We propose that targeting Rab8a might serve as a strategy to restore DC functionality in the context of immune aging.…”
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Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media. by Stephanie Kuhn, Neil Ingham, Selina Pearson, Susan M Gribble, Stephen Clayton, Karen P Steel, Walter Marcotti

“…However, it is unknown whether Tc1 mice exhibit a hearing phenotype and might thus represent a good model for understanding the hearing loss that is common in Down syndrome. …”
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Antenatal Corticosteroids and Postnatal Fluid Restriction Produce Differential Effects on AQP3 Expression, Water Handling, and Barrier Function in Perinatal Rat Epidermis by Johan Agren, Sergey Zelenin, Lill-Britt Svensson, Lene N. Nejsum, Soren Nielsen, Anita Aperia, Gunnar Sedin

“…The water and glycerol channel aquaglyceroporin-3 (AQP3) is abundant in fetal epidermis and might influence epidermal water handling and transepidermal water flux around birth. …”
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Knowledge, attitude and practice on ovarian reserve function among women of childbearing age: a prospective cross-sectional study in Chongqing and surrounding regions by Li Yang, Yu Deng, Jun Hu, Hongying Zhang, Youfang Yuan

“…The total influence of knowledge on practice was significant (β=0.525, p=0.012).Conclusions The women living in Chongqing and surrounding regions had good knowledge, moderate attitude and good practice towards ovarian reserve function. The knowledge aspect can be further improved by education, which in turn might also improve practice among women of childbearing age.…”
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