The mediating role of instrumental activities of daily living between cognitive function and depressive symptoms in community-dwelling older adults: the Arao study by Maiko Nagaoka, Katsuya Nagaoka, Naoto Kajitani, Seiji Yuki, Asuka Koyama, Kazuhiro Yoshiura, Kazuki Honda, Yusuke Miyagawa, Shuken Boku, Noboru Fujise, Minoru Takebayashi

“…Conclusions IADL was a mediating factor in the relationship between cognitive function and depressive symptoms, and cognitive function contributed to depressive symptoms through IADL. …”
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Expanded CD133+ Cells from Human Umbilical Cord Blood Improved Heart Function in Rats after Severe Myocardial Infarction by Alejandro Correa, Gabriel Salles Ottoboni, Alexandra Cristina Senegaglia, Luiz Guilherme Achcar Capriglione, Nelson Itiro Miyague, Lidiane Maria Boldrini Leite, Valderez Ravaglio Jamur, Carmen Lúcia Kuniyoshi Rebelatto, Márcia Olandoski, Paulo Roberto Slud Brofman

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RETRACTED ARTICLE: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells by Ziyi Zhao, Yingwei Sun, Jing Tang, Yuting Yang, Xiaochao Xu

“…This suggests that LRPPRC might be a promising therapeutic target for osteosarcomas.…”
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Soil properties and plant functional traits have different importance in shaping rhizosphere soil bacterial and fungal communities in a meadow steppe by Shanshan Song, Xian Yang, Rong Tang, Yongqiang Zhang, Zhiyao Tang

“…ABSTRACT Soil properties and plant functional traits are important factors influencing rhizosphere microbial diversity and composition. …”
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PNPLA3 in largemouth bass (Micropterus salmoides): Molecular cloning, functional characterization, and its role in high glucose-induced lipid synthesis by Yan-Bin Yang, Ying-Ying Xu, Hao Ding, Jia-Min Ma, Qing-Hui Ai, Lei Zhou, Chao Xu

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Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeli... by Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang

“…Monocyte-derived macrophages and self-recruiting neutrophils contributed to impairment of mLVs in the acute stage, while PGF might serve as a key factor promoting early meningeal lymphatic function repair following the inflammatory response. …”
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Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents by Mariaelena Capone, Gabriele Madonna, Ester Simeone, Paolo A Ascierto, Antonio Sorrentino, Roberta Turiello, Elva Morretta, Maria Chiara Monti, Rosa Azzaro, Silvana Morello, Pasquale Del Gaudio

“…Early during therapy exosomal PD-L1 increased in responders, while exosomal CD73 resulted significantly increased in non-responders.Conclusions CD73 expressed on exosomes from serum of patients with melanoma produces adenosine and contributes to suppress T-cell functions. Early on-treatment, elevated expression levels of exosomal CD73 might affect the response to anti-PD-1 agents in patients with melanoma who failed to respond to therapy.…”
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Intervention of muscle-building and antifrailty exercise combined with Baduanjin for frailty of different functional levels: study protocol for a randomised controlled trial by Chao Chen, Fang Wang, Shuaixuan Xu, Zhuyun Gong, Mengyu Cao, Jinwei Liu, Nihui Zhang, Jingwen Kang, Chuang Xu, Nan Peng

“…Frailty has also been associated with a range of adverse events, which might increase the risks of disability, falls, fractures, delirium and death. …”
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Unresponsiveness induced by sevoflurane and propofol is associated with reduced basal forebrain cholinergic nuclei functional connectivity in humans, a pilot exploratory study by Juliana Zimmermann, Rachel Nuttall, Daniel Golkowski, Gerhard Schneider, Andreas Ranft, Rüdiger Ilg, Afra Wohlschlaeger, Christian Sorg, Marlene Tahedl

“…A significant source of cholinergic innervation comes from basal forebrain cholinergic nuclei (BFCN), with bi-directional connections between anterior BFCN and the default mode network (DMN). Since DMN functional connectivity (FC) is consistently reduced during anesthesia-induced unresponsiveness in humans, we hypothesized that BFCN-FC during anesthesia-induced unresponsiveness is reduced and particularly, anterior BFCN-FC reductions might be related to DMN-FC reductions. …”
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Physicochemical and functional optimization of probiotic yogurt with encapsulated Lacticaseibacillus paracasei E1 enriched with green tea using Box–Behnken design by Muhaimin Rifa'i, Mochammad Fitri Atho'illah, Siti Nur Arifah, Aditya Ragil Suharto, Aghnia Nuri Fadhilla, Nur Alfi Maghfirotus Sa'adah, Esha Ardiansyah, Rahmi Izati, Belinda Nabiila Al Faizah, Dawama Nur Fadlilah, Septhyanti Aprilia Kavitarna, Shinta Oktya Wardhani, Wisnu Barlianto, Hideo Tsuboi, Yoga Dwi Jatmiko

“…Incorporating GTY with encapsulated LpE1 might be promising to improve the physicochemical properties and functional values of yogurt.…”
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Systemic S100A8/A9 in patients with moderate to severe acute ischemic stroke: Exploratory analysis of inflammation and functional outcome by Christoph Vollmuth, Felipe A. Montellano, Cornelia Fiessler, Fabian Essig, Christian Hametner, Alexander M. Kollikowski, Vivian Vogt, Mirko Pham, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Michael K. Schuhmann

“…At 3 months, 192 of 272 (71 %) patients had poor functional outcome, who had significantly higher systemic plasma levels of S100A8/A9 at baseline [median: 525 ng/ml (IQR: 342–897)] than those with good functional outcome [397 ng/ml (IQR: 232–580); p = 0.001]. …”
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Functional Performance Decline Outperforms Sarcopenia and Its Components in Predicting New-Onset Chronic Kidney Disease: A Nationwide Multicenter Study by Liangyu Yin, Furong Li, Tangli Xiao, Jun Zhang, Yan Li, Jicong Luo, Jinghong Zhao, Jiachuan Xiong

“…Plain-Language Summary: This study looked at how physical function, sarcopenia (loss of muscle mass and strength), and related factors might predict the development of chronic kidney disease (CKD). …”
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Back-channeling in Celebrities Interviews: A Socio-discoursal Study by Zainab Saad Mohammed, Ahmed Adel Nouri

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Harness the internal stress in ceramics by Lianmeng Zhang

“…This stress engineering strategy gives rise to significantly enhanced mechanical properties and unique functional characteristics of the ceramic matrix, which might greatly influence the future design of high-performance ceramic composites.…”
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Aeromonas hydrophila RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types by Qilu Ye, Robert Eves, Tyler D. R. Vance, Thomas Hansen, Adam P. Sage, Andrea Petkovic, Brianna Bradley, Carlos Escobedo, Laurie A. Graham, John S. Allingham, Peter L. Davies

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Quadrotor Trajectory Planning with Tetrahedron Partitions and B-Splines in Unknown and Dynamic Environments by Jiayu Men, Jesús Requena Carrión

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Les réponses macroéconomiques des pays du CARICOM aux chocs extérieurs majeurs d’aujourd’hui by Louis Dupont

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Robust phylogenetic profile clustering for Saccharomyces cerevisiae proteins by Paul M. Harrison

“…Methods to identify gene origination might simply use the last common ancestor to contain an ortholog as the putative gene origination point, or use a heuristic threshold that allows for a certain amount of missing orthologs in the cohort of species examined. …”
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New Insights Into Visual Word Recognition: Analyzing Error Distribution in Typical Readers by Fanny Grisetto, Clémence Roger, Gwendoline Mahé

“…The comparison of correct and incorrect reaction times (RTs) and the use of Conditional Accuracy Functions (CAFs) in lexical decision tasks have led to inconclusive findings. …”
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Smartphone tests quantify lower extremities dysfunction in multiple sclerosis by Kimberly Jin, Peter Kosa, Bibiana Bielekova

“…To address this need, we have developed a suite of smartphone tests, called neurological functional test suite (NeuFun-TS), designed to replicate traditional neurological examination. …”
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