Ablation of NK Cell Function During Tumor Growth Favors Type 2-Associated Macrophages, Leading to Suppressed CTL Generation by Anja B. Geldhof, Jo A. van Ginderachter, Yuanqing Liu, Wim Noël, Patrick de Baetselier

“…The results indicate that the accessory function of NK can depend at least partially on their ability to preferentially engage arginase-producing cells, suggesting that NK/macrophage lytic interactions might be involved in the switch from Type 2 to Type 1-dependent immune responses.…”
Get full text

Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibility by Clara Delaroque, Héloïse Rytter, Erica Bonazzi, Marine Huillet, Sandrine Ellero-Simatos, Eva Chatonnat, Fuhua Hao, Andrew Patterson, Benoit Chassaing

Get full text

Different dry-wet pulses favor different functional strategies: A test using tropical dry forest tree species. by Flor Vega-Ramos, Lucas Cifuentes, Fernando Pineda-García, Todd Dawson, Horacio Paz

“…As expected, different dry-wet pulse scenarios favored different plant functional strategies. Contrary to predictions, the most tolerant outperformed the most avoiders under all drought scenarios, while rapid water-exploiters thrived under non-drought conditions. …”
Get full text

Association of cerebral oxygenation with estimated glomerular filtration rate and cognitive function in chronic kidney disease patients without dialysis therapy. by Haruhisa Miyazawa, Susumu Ookawara, Kiyonori Ito, Yuichiro Ueda, Katsunori Yanai, Hiroki Ishii, Yuko Mutsuyoshi, Taisuke Kitano, Mitsutoshi Shindo, Akinori Aomatsu, Keiji Hirai, Taro Hoshino, Yoshiyuki Morishita

“…Furthermore, cerebral rSO2 monitoring, which reflected MMSE scores, might be a useful method for assessing cognitive function in CKD patients.…”
Get full text

Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study. by Md Mostafa Kamal, Kazi Fahmida Haque Shantanu, Shamiha Tabassum Teeya, Md Motiar Rahman, A K M Munzurul Hasan, Douglas P Chivers, Tanveer A Wani, Atekah Hazzaa Alshammari, Mahesh Rachamalla, Francisco Carlos da Silva Junior, Md Munnaf Hossen

“…Finally, MD simulation revealed consistent fluctuation in RMSD and RMSF, consequently Rg, hydrogen bonds, and PCA in the mutant proteins compared with wild-type, which might alter the functional and structural stability of CTLA4 protein. …”
Get full text

Functional Studies on the <i>LiAG1</i> Gene of <i>Lilium</i> ‘Ice Pink Queen’ in Flower Development by Lili Xue, Jingqi Dai, Ruyu Fu, Nana Wu, Jiaxuan Yu, Jie Dong, Tao Yang, Jinping Fan

Get full text

TIM-3 plays a more important role than PD-1 in the functional impairments of cytotoxic T cells of malignant Schwannomas by Zhao Li, Xiaobing Liu, Rongbin Guo, Pengfei Wang

“…Together, our results suggested that PD-1 and TIM-3 blockade might be necessary in developing effective immunotherapeutic strategies in malignant Schwannoma, in which TIM-3 may play a more important role.…”
Get full text

The neutrophil-to-lymphocyte ratio for acute allograft rejection and delayed graft function prediction in kidney transplant recipients: a meta-analysis by Ryuu Damara Parisudha, Tanaya Ghinorawa, Indrawarman Soero Hardjo

“…Background : The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been the focus of several observational studies investigating their roles in acute allograft rejection (AR) and delayed graft function (DGF) among kidney transplant (KT) recipients. …”
Get full text

Quality of life and parental stress related to executive functioning, sensory processing, and activities of daily living in children and adolescents with neurodevelopmental disorde... by Vanesa Lobato-Ruiz, Dulce Romero-Ayuso, Abel Toledano-González, José Matías Triviño-Juárez

“…The study revealed that QoL and parental stress are closely linked to functioning in ADLs and executive functioning of children with neurodevelopmental disorders. …”
Get full text

Quality of life and objective functional impairment in lumbar spinal stenosis: a protocol for a systematic review and meta-analysis of moderators by Andrea Pozza, Fabio Ferretti, Anna Coluccia, Roberto Gusinu, Giacomo Gualtieri, Vitaliano Francesco Muzii

“…There is no comprehensive review on quality of life and objective functional impairment in LSS. This paper presents the protocol of the first systematic review and meta-analysis summarising evidence about quality of life and functional impairment in patients with LSS compared with healthy controls. …”
Get full text

INFLUENCE OF CHRONIC NEUROGENIC PAIN ON THE DYNAMICS OF THE NO-SYSTEM FUNCTIONING DURING MELANOMA B16/F10 GROWTH IN MALE MICE by O. I. Kit, I. M. Kotieva, E. M. Frantsiyants, E. I. Surikova, I. V. Kaplieva, V. A. Bandovkina, L. K. Trepitaki, I. V. Neskubina, Ju. A. Pogorelova

“…Male mice with B16 melanoma growing in the presence of cnp demonstrated a more active functioning of the no-system already from week 1, compared to standard tumor growth, which might result in a greater rate of growth of melanoma with cnp. …”
Get full text

Beta vulgaris L. beetroot protects against iron-induced liver injury by restoring antioxidant pathways and regulating cellular functions by Oluwafemi Adeleke Ojo, Temiloluwa Rhoda Adeyemo, Matthew Iyobhebhe, Moses Dele Adams, Rotdelmwa Maimako Asaleye, Ikponmwosa Owen Evbuomwan, Jadesola Abdurrahman, Tobiloba Christiana Maduakolam-Aniobi, Charles Obiora Nwonuma, Olalekan Elijah Odesanmi, Adebola Busola Ojo

Get full text

Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study by Lina Münker, Martin Køster Rimvall, Lisbeth Frostholm, Eva Ørnbøl, Kaare Bro Wellnitz, Pia Jeppesen, Judith Gerarda Maria Rosmalen, Charlotte Ulrikka Rask

“…Abstract Background Functional somatic symptoms (FSS), which commonly cannot be attributed to well-defined organic pathology, often co-occur with internalizing psychopathology and fluctuate throughout different life stages. …”
Get full text

Huaju Xiaoji Formula Regulates ERS-lncMGC/miRNA to Enhance the Renal Function of Hypertensive Diabetic Mice with Nephropathy by Zeng Zhang, Xiaodong Fu, Fengzhu Zhou, Duanchun Zhang, Yanqiu Xu, Zhaohua Fan, Shimei Wen, Yanting Shao, Zheng Yao, Yanming He

“…In our previous study, the Huaju Xiaoji (HJXJ) formula promoted the renal function of patients with diabetes and hypertensive nephropathy. …”
Get full text

A Method for Assessing the Prevalence of Food Insecurity in Older Adults Based on Resource Constraints and Food-Related Physical Functioning Limitations by AnnieBelle J Sassine, Matthew P Rabbitt, Alisha Coleman-Jensen, Alanna J Moshfegh, Nadine R Sahyoun

“…Background: Older adults with food-related physical functioning limitations often face food insecurity because of challenges that go beyond resource constraints. …”
Get full text

Effect of Mind Sound Resonance Technique on Pulmonary Function and Smoking Behavior among Smokers – A Prospective Randomized Control Trial by K. S. Moodala Girishankara, Shivaprasad Shetty, Krithika A. Ramaswamy, Prashanth Shetty

“…Conclusion: The practice of MSRT might help in improving the lung function and also reduce the withdrawal symptoms, craving, urge, and negative affect among smokers. …”
Get full text

Cu⁰-Functionalized, ZIF-8-Derived, Nitrogen-Doped Carbon Composites for Efficient Iodine Elimination in Solution by Jiuyu Chen, Chensheng Gao, Jingwen Chen, Fei Liu, Zhiwen Liu

“…Herein, Cu⁰-nanoparticles-functionalized, ZIF-8 (Zeolite Imidazole Framework-8)-derived, nitrogen-doped carbon composites (Cu@Zn-NC) were synthesized by ball milling and pyrolysis processes. …”
Get full text

The Impact of Serum Parameters Associated with Kidney Function on the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients Undergoing Radical Surgery by Bin Zhang, Xu-Rui Liu, Xiao-Yu Liu, Bing Kang, Chao Yuan, Fei Liu, Zi-Wei Li, Zheng-Qiang Wei, Dong Peng

Get full text

Disrupted small-world architecture and altered default mode network topology of brain functional network in college students with subclinical depression by Bo Zhang, Shuang Liu, Sitong Chen, Xiaoya Liu, Yufeng Ke, Shouliang Qi, Xinhua Wei, Dong Ming

“…However, the brain network topology of ScD remains poorly understood, impeding our comprehension of the neuropathology underlying ScD. Methods Functional networks of individuals with ScD (n = 26) and healthy controls (HCs) (n = 33) were constructed based on functional magnetic resonance imaging data. …”
Get full text

Genetic manipulation of porcine deltacoronavirus reveals insights into NS6 and NS7 functions: a novel strategy for vaccine design by Mengjia Zhang, Wan Li, Peng Zhou, Dejian Liu, Rui Luo, Anan Jongkaewwattana, Qigai He

Get full text