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Passiivne süntees kultuurifenomenoloogias / Passive Synthesis in Cultural Phenomenology
Published 2024-12-01“…In active genesis, the Ego functions through specific Ego-acts that are productively constitutive. …”
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4462
Single-stage surgery with antibiotic-loaded hydrogel-coated implants versus two-stage surgery for chronic periprosthetic hip joint infection in French tertiary referral hospitals:...
Published 2025-02-01“…The single-stage procedure is thought to be less susceptible to late functional complications with a shorter, single hospital stay. …”
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4463
Sequentially assembled co-delivery nanoplatform of SIRT1 protein and SOX9-expressing plasmid for multipronged therapy of intervertebral disc degeneration
Published 2025-05-01“…RNA sequencing suggested that inhibition of the Nod-like receptor signaling might be the mechanism behind their therapeutic effects. …”
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4464
Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of β2-Adrenergic Receptor
Published 2018-01-01“…Furthermore, TERT, an Ang II-AT1R interaction blocker, restored the interaction between AT1R and ADRB2, suggesting that Ang II might induce the dysfunction of EPCs via downregulation of ADRB2, and an AT1R blocker could prevent Ang II-mediated ADRB2 depletion in EPCs. …”
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4465
Utilization of universal-targeting mSA2 CAR-T cells for the treatment of glioblastoma
Published 2025-12-01“…Although such an approach might circumvent the aforementioned challenges, the potential of mSA2 CAR-T cells for brain tumor treatment remains unexplored. …”
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4466
Genome-wide identification and characterization of the Lateral Organ Boundaries Domain (LBD) gene family in nine Rosaceae species and expression pattern in Prunus mume
Published 2024-01-01“…Our studies offer important data about the development of the LBD family in Rosaceae and the subsequent validation of LBDs' functional genes in P. mume.…”
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4467
Prevalence and Clinical Characteristics of NEUROD1‐MODY in Chinese Early‐Onset Type 2 Diabetes Mellitus and a Literature Review
Published 2025-04-01“…Conclusions NEUROD1‐MODY in Chinese patients with EOD is not common (≤ 0.15%). The P197H might account for MODY in Chinese with a higher penetrance than Caucasian and needs further exploration. …”
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4468
Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota
Published 2022-12-01“…This fundamental evidence might provide references for modulating maternal nutrition to enhance early-life gut health and prevent gut inflammation.…”
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Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon
Published 2024-12-01“…Conclusions: The associated factors suggest that it might be of interest to fight inactivity and encourage early and long-term education to prevent DS and/or CI among older adults.…”
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4471
Eurycomalactone switched hepatocellular carcinoma cells into quiescence through 5’tRFAla/DVL/β-catenin pathway inhibition
Published 2025-03-01“…Abstract Although tsRNA has been demonstrated to modulate various physiological processes analogous to miRNA, the potential regulatory functions and mechanisms of tsRNAs related to the pharmacological effects of small molecule drugs remain unclear. …”
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4472
Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages
Published 2020-05-01“…Interfering with this pathway might provide novel therapeutic strategies.…”
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4473
Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using s...
Published 2025-07-01“…Despite its significance, the specific functions and mechanisms of PANoptosis within the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) remain unclear. …”
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4474
Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a Morganella morganii isolate from poultry
Published 2025-03-01“…This protein shares the highest aa identity of 55.6% with the functionally characterized protein FosA and has all the essential functional residues of FosA proteins. …”
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4475
Divergence in physical, chemical, and biological soil properties caused by different long-term bare fallow management and natural succession
Published 2025-07-01“…The absence of plants has profound effects on many ecosystem functions of soil. Long-term bare fallow trials are valuable tools for studying the dynamics in soil carbon decline and associated soil degradation. …”
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4476
Multi-omics analysis unveils the predictive value of IGF2BP3/SPHK1 signaling in cancer stem cells for prognosis and immunotherapeutic response in muscle-invasive bladder cancer
Published 2024-10-01“…Additionally, these findings suggested that the IGF2BP3/SPHK1 signaling might serve as a biomarker for prognosis and immunotherapy response in MIBC.…”
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4477
Thymic Microenvironment Remodeling in Cancer Cachexia as a Determinant of Checkpoint Inhibitor Efficacy and Toxicity
Published 2025-08-01“…Conclusions Cancer cachexia disrupts mFbs maturity, affecting T cell negative selection and expanding the TCR repertoire against tissue‐restricted antigens. This might mediate the adverse and favourable effects of ICIs as anticancer treatments.…”
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SPECIFICS OF SUBFRACTIONAL SPECTRUM OF APOLIPOPROTEIN B RELATED LIPOPROTEINES IN CAROTID OR CORONARY ATHEROSCLEROSIS PATIENTS
Published 2016-10-01“…Apolipoprotein (apo)B-containing lipoproteines of low density are heterogeneous by their nature, and differ by their lipid and protein contents, charge, particle size and functional activity. High blood level of small dense particles of low-density lipoproteines (LDL) is related to higher risk of coronary heart disease 3-5 times irrelevant to cholesterol level they contain.Aim. …”
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Kladistik Genera Famili Leiognathidae melalui Penelusuran Morfologi Eksternal dan Otolith
Published 2025-03-01“…Geographical barriers and environmental factors might be the main factor in the occurrence of different morphological and otolith adaptations. …”
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4480
Developments in Legal Education: Beyond the Primary School Model
Published 1991-01-01“…Two other recent publications perform similar functions for legal scholarship: the now venerable Modern Law Review marked its fiftieth birthday with an illuminating survey of the state of legal scholarship in the common law world; this exhibits the wry acceptance of lowering of sights by an ageing radical. …”
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