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4441
Evaluating the Effectiveness of a Mobile App for Breast Cancer Self-Management on Self-Efficacy: Nonrandomized Intervention Trial
Published 2025-03-01“…MethodsThe Cancer Manager (CAMA) app was developed to assist in the self-management of patients with breast cancer and survivors of cancer according to cancer trajectory. Its functionalities include providing evidence-based digitalized information created by experts, managing patients’ medication and medical appointment schedules, and providing a delayed question and answer system for patients to query health care professionals. …”
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4442
Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine
Published 2022-12-01“…To shed light on the current political scenario, we propose here to reconsider the political from below, and namely by looking where only disruptions to the neo-liberal model of functioning democracies have been detected so far - and thus in most manifestations referred to as 'chaos', 'statelessness' or absence of 'political culture'. …”
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4443
Exploring Salvia miltiorrhiza’s Therapeutic Effects on Adenomyosis by Inhibiting TNF-α/HIF-1α/IL-17-Driven Inflammatory Cascade: Mechanistic Insights...
Published 2025-08-01“…Network pharmacology predicted that DS might exert therapeutic effects on adenomyosis by modulating the TNF-α/IL-17/HIF-1α signaling pathways through key targets, including TNF, IL1β, MMP2, ESR1, PTGS2, STAT3, BCL2, AKT1, MMP9, and EGFR. …”
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4444
Language and ethnicity in Central and Eastern Europe: Some theoretical aspects
Published 2025-05-01“…The author concludes that language has played both a symbolic and a functional role in the centralisation of Central and Eastern Europe. …”
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4445
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4446
Quercetin modulates transcription of the apoptotic and CatSper genes and optimises post thaw viability and kinematics of buck spermatozoa
Published 2025-07-01“…Abstract Oxidative stress during semen processing affects sperm membrane integrity, leading to compromised sperm membrane functions and kinematics, often resulting in reproductive losses. …”
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4447
The Influence of Zero‐Profile Implant Selection on the Outcomes of Anterior Cervical Discectomy and Fusion
Published 2025-03-01“…Therefore, a larger height might be a better choice for achieving a satisfactory long‐term prognosis if Zero‐profile implants of adjacent size both fit the disc space properly.…”
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4448
CO13 | Genetic background in hypercholesterolemic patients framing cardiovascular risk
Published 2025-08-01“…Many FH subjects (about 60%) did not demonstrate functional mutations in major candidate genes (LDLR, APOB, PCSK9, LDLRAP1). …”
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4449
Identification of early Alzheimer’s disease subclass and signature genes based on PANoptosis genes
Published 2024-11-01“…Therefore, targeting PANoptosis genes might lead to novel therapeutic targets and clinically relevant therapeutic approaches. …”
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4450
Multiple Hub Genes as Diagnostic and Therapeutic Targets Inducing Inflammation and Angiogenesis in Retinopathy of Prematurity
Published 2025-08-01“…WGCNA was utilized to obtain oxygen-induced retinopathy (OIR)-related modules, and then key genes were obtained in the intersection of DEGs and the above modules. Biological functions and pathways of key genes were enriched through DAVID, Metascape and Gene set enrichment analysis. …”
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4451
CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis
Published 2025-02-01“…Abstract Knee arthrofibrosis, characterized by excessive matrix protein production and deposition, substantially impairs basic daily functions, causing considerable distress and financial burden. …”
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4452
Disturbed hierarchy and mediation in reward-related circuits in depression
Published 2025-01-01“…Utilizing existing DBS targets as seeds, we conducted step-wise functional connectivity (sFC) analyses to delineate hierarchical pathways linking to cerebral cortices. …”
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4453
Ambiguous results of balloon angioplasty for central vein stenosis in hemodialysis patients with native arteriovenous fistula
Published 2020-04-01“…In the experimental group, strong negative correlation between primary patency and functional primary patency was detected: r = –0.627 [95% CI –0.787; –0.388], p < 0.0001. …”
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4454
Causal relationships between four types of lipids and breast cancer risk with potential mediators: evidence from Mendelian randomization study and bioinformatics analysis
Published 2025-05-01“…The expression of ZC3HC1 showed no significant expression difference between normal and BC tissues (P > 0.05), which might indicate a carcinogenic effect independent of expression levels but driven by functional alterations induced by variants (C > T). …”
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4455
Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i>
Published 2025-07-01“…The RasGAP SH3 domain binding protein (G3BP) is a highly conserved family of proteins in eukaryotic organisms that coordinates signal transduction and post-transcriptional gene regulation and functions in the formation of stress granules. G3BPs have important roles in abiotic/biotic stresses in mammals, and recent research suggests that they have similar functions in higher plants. …”
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4456
Patient-reported Outcome Measures and Decision Regret After Prostate-specific Membrane Antigen–targeted Radioguided Surgery for Oligorecurrent Prostate Cancer
Published 2024-12-01“…Conclusions and clinical Implications: We recorded no significant decrease in quality of life or any functional status domain, except sexual. While decision regret was low, sexual functioning might deteriorate further. …”
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4457
Abundance of a metabolically active subpopulation in dedifferentiated adipocytes inversely correlates with body mass index
Published 2025-07-01“…Objective: The cellular composition and functionality of adipose tissue are key determinants of metabolic diseases associated with adipose tissue dysregulation, such as obesity. …”
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4458
Effect of communicating genetic risk of type 2 diabetes and wearable technologies on wearable device-measured behavioural outcomes in East Asians: protocol of a randomised controll...
Published 2024-12-01“…It is uncertain whether risk communication might enhance the effects of wearable devices. We aim to assess the effects of communicating genetic risk for T2D alone or in combination with wearable device functions on wearable device-measured PA among overweight or obese East Asians.Methods and analysis In a parallel group, randomised controlled trial, 355 overweight or obese East Asian individuals aged 40–60 years are allocated into one of three groups: one control and two intervention groups. …”
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4459
Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon
Published 2024-12-01“…Under 150 mmol/L saline-alkali stress, applying a low dose of HA-MBC still played a role in ameliorating soil and mitigating stress, while applying high doses of biochar inhibited the improvement of indicators. This might be due to excessive application of HA-MBC causing surface functional groups to aggregate toxic substances and salt ions excessively and compete for nutrients, subsequently reducing AMF colonization rates, weakening the mycorrhizal symbiosis, and hence diminishing the photosynthetic parameters of muskmelon. …”
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4460
Pain After Lower Extremity Fracture Surgery: What Is Normal and How Is It Impacted by Individual-specific and Caregiver-specific Psychosocial Factors?
Published 2025-05-01“…HRQOL was assessed via PROMIS Global Health, and functional recovery was assessed via PROMIS Mobility. …”
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