Identification of anoikis-related molecular patterns and the novel risk model to predict prognosis, tumor microenvironment infiltration and immunotherapy response in bladder cancer by Luochen Zhu, Feng Xiao, Yi Hou, Shenjun Huang, Yanyan Xu, Xiaohong Guo, Xinwei Dong, Chunlu Xu, Xiaolei Zhang, Haijuan Gu

“…In addition, representative genes were evaluated using immunohistochemistry in clinical specimens, and in BLCA cell lines, functional experiments were performed to determine the biological behavior of hub gene PLOD1.ResultTwo definite anoikis subgroups were identified. …”
Get full text

A plasmid-mediated type III secretion system associated with invasiveness and diarrheagenicity of Providencia rustigianii by Jayedul Hassan, Atsushi Hinenoya, Noritoshi Hatanaka, Sharda Prasad Awasthi, Goutham Belagula Manjunath, Nahid Rahman, Jyoji Yamate, Shota Nakamura, Daisuke Motooka, Akira Nagita, Shah M. Faruque, Shinji Yamasaki

“…This is the first report of a functional and mobile T3SS in P. rustigianii and its association with invasiveness and diarrheagenicity of this bacterium. …”
Get full text

BCMA CAR-T therapy combined with pomalidomide is a safe and effective treatment for relapsed/refractory multiple myeloma by Yuhan Yan, Yixuan Tu, Qian Cheng, Jian Zhang, Erhua Wang, Zuqun Deng, Yan Yu, Liwen Wang, Rui Liu, Ling Chu, Liqing Kang, Jing Liu, Xin Li

“…Long-term pomalidomide therapy, which potentiates T-cell functionality, might enhance the efficacy of BCMA CAR T-cell therapy. …”
Get full text

Elevation of p53 sensitizes obese kidney to adriamycin-induced aberrant lipid homeostasis via repressing HNF4α-mediated FGF21 sensitivity by Jiahao Li, Yufeng Tang, Guangping Lu, Qingbo Liu, Yuanfang Guo, Jie Wang, Mengjie Xiao, Ting Gao, Xiaohui Zhang, Junlian Gu

“…The specific effects of p53/FGF21 on the regulation of lipid metabolism disorders and its downstream mediators in kidney were subsequently elucidated using a combination of functional and pathological analysis, RNA-sequencing, molecular biology, and in vitro approaches. …”
Get full text

The Processes of Intelligent Firefighting in Seawater Tunnel: a Case Study of Karnaphuli Tunnel in Bangladesh by Yan Yi, Tao Yang, Songsong Xiao, Xing Liu, Min Deng, Zewen Sun, Zhengyang Fan, Hao Huang

“…Considering the characteristics of marine corrosion, a two-layer anti-corrosion structure with epoxy zinc-based powder coating as the bottom layer and functional coating as the surface layer was adopted. …”
Get full text

A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome by Moritz Güttes, Marianna Lucio, Adam Skornia, Eva Rühl, Fritz Steußloff, Julia Zott, Christian Mardin, Wolfgang Mehringer, Marion Ganslmayer, Georg Michelson, Bettina Hohberger

“…RT and CR detecting 3D-stimuli in a virtual 3D- environment might offer novel functional diagnostic approaches in PCS.…”
Get full text

MORALITY, MEDICAL ETHICS AND MEDICAL LAW by P. I. Yatsenko

“…After establishing regulatory frameworks, implementation of health activities ensures the effective implementation of regulatory functions and security law. Moral behavior is the rule, which is common for any society, including the medical. …”
Get full text

RIGHT VENTRICLE MYOCARDIUM CONTRACTILITY AS PARAMETER OF CARDIAC RESYNCHRONIZATION EFFICACY by D. I. Lebedev, S. N. Krivolapov, K. V. Zavadovsky, S. I. Sazonova, R. S. Karpov, S. V. Popov

“….), heart failure (HF) of III functional class (FC) by NYHA, ejection fraction (EF) of the left ventricle (LV) was 30,1±3,8%, 6-minute walking distance — 290,5±64,3 m, end-diastolic volume (EDV) — 220,7±50,9 mL. …”
Get full text

Enhancing direct carbonation performance of basic oxygen furnace slag through potassium chloride activation by Rong SUN, Weicheng XU, Hongming LONG, Rufei WEI

“…However, excessive KCl might lead to collapse or blockage of the pore structure and cover the active sites on the surface, thereby reducing the carbonation performance of BOF slag. …”
Get full text

Implementing and Evaluating a Mobile Phone–Supported and Family-Centered Rehabilitation Program for People With Stroke in Uganda (F@ce 2.0): Protocol for a Randomized Controlled Tr... by Gunilla Eriksson, Julius Tunga Kamwesiga, Uno Fors, Tonny Oyana, Lena von Koch, Charlotte Ytterberg, Susanne Guidetti

“…An additional aim is to explore experiences of participating in F@ce 2.0 and plausible mechanisms of impact that might explain the potential effects of F@ce 2.0. …”
Get full text

Distonia virtual por infarto talâmico posterolateral ventral: relato de caso Virtual dystonia due to a posteroventrolateral thalamic infarct: case report by Ricardo De Oliveira-Souza, Maria Elena de Lima Martins, Pedro Ângelo Andreiuolo, Andreia Rotmeister

“…Lifting the foot deprived S-I of tonic inputs conveyed by undamaged contact-pressure pathways, a functional effect promptly reversed by placing the foot back against the ground. …”
Get full text

Association of brain-derived neurotrophic factor and nerve growth factor gene polymorphisms with susceptibility to migraine by Coskun S, Varol S, Ozdemir HH, Agacayak E, Aydın B, Kapan O, camkurt MA, Tunc S, Cevik MU

“…Our findings suggest that the NGF rs6330*T minor allele might be nominated as a risk factor for developing aura in migraine disease. …”
Get full text

China’s cultivated land threshold from the perspective of food security by ZHAO Xiaoyu, SUN Chunqiang, CUI Rongguo, CHEN Jing, ZHANG Xiaoyu, CAO Tingyu, LI Chao

“…[Conclusion] Given the current rate of cultivated land reduction, it is expected that the amount of cultivated land might drop below the high value of cultivated land minimum demand by 2035. …”
Get full text

Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications by Can Qi, Can Qi, Ziwei Zhao, Lin Chen, Le Wang, Yun Zhou, Guochen Duan, Guochen Duan

“…Differential analysis was performed to identify DEGs between subtypes. Functional items and related pathways of DEGs were identified using enrichment analysis. …”
Get full text

A novel glycolysis-related gene signature for predicting prognosis and immunotherapy efficacy in breast cancer by Rui Huang, Rui Huang, Yi Li, Kaige Lin, Luming Zheng, Xiaoru Zhu, Xiaoru Zhu, Leqiu Huang, Leqiu Huang, Yunhan Ma

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were used to identify the potential biological functions of GRPGs. cBioPortal database was used to explore the tumor mutation burden (TMB). …”
Get full text

Preparation of PET matrix gradient composite fiber membrane for coal mine and Study on the dust filtration-moisture permeability by Gang ZHOU, Zhuo XU, Liwei JIANG, Guanshuang CHEN, Yunlong MA, Rulin LIU, Yongmei WANG

“…Moreover, the distribution of surface elements and functional groups of each fiber membrane was consistent with its feature. …”
Get full text

A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…We conclude that including green forage in the diet can stimulate a more taxonomically and functionally diverse rumen microbiome with positive effects on microbiota total biodiversity, which might improve the health and productivity of the buffaloes. …”
Get full text

Evaluation of the relationship between cytochrome P450 (CYP) 1A2 gene copy number variation and CYP1A2 protein content and enzyme activity in canine liver by Francisco Gonzales Zamora, Hannah Bigelow, Hong Yang, Tania Perez Jimenez

“…If these additional copies are functional, dogs with more CYP1A2 gene copies may exhibit faster drug clearance, potentially affecting appropriate drug dosing. …”
Get full text

An immune-related seven-gene signature for predicting lymph node metastasis in breast cancer by Yun Hu, Lanqiao Sun, Jinhua Wang, Yuan Ji, Lili Feng

“…We divided BC patients into lymph node positive and negative groups to identify immune-related lymph node-associated differentially expressed genes (DEGs) for functional enrichment analysis and protein-protein interaction (PPI) network. …”
Get full text

PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease

“…Although data is still limited, several hypotheses and emerging evidence suggest that extracellular vesicles (EVs) might exert a functional role in the pathogenesis of PSVD. …”
Get full text