Redefining boundaries: unveiling the schism in teacher-parent perceptions of educational engagement by Yael Fisher, Shiran Baissberg

“…To collect data, participants were asked to complete an anonymous self-report parental involvement questionnaire in which they classified parental functions based on their degree of agreement, ranging from absolute disagreement to approval and desire for such activities. …”
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Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer by Qunfang Zhou, Jingqiang Wu, Jiaxin Bei, Zixuan Zhai, Xiuzhen Chen, Wei Liang, Jing Meng, Mingyu Liu

“…We constructed and validated a LASSO model based on these genes in both sets and two external datasets. Functional, immune infiltration, and mutation analyses were performed on high and low-risk groups. …”
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A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds by C. Persichilli, S. Biffani, G. Senczuk, M. Di Civita, M.K. Bitew, A. Bosco, L. Rinaldi, S. Grande, G. Cringoli, F. Pilla

“…In this study, we took advantage of the use of EBVs as a metric for GIN resistance in a case-control genome-wide framework and successfully identified several genomic regions that might be involved in the trait. The presence of overlapping functional pathways related to different genes in the two breeds seems to reinforce the idea of the polygenicity of this trait, and further studies are needed in order to make selection schemes an effective tool to contrast GINs.…”
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Synergetic Urban Landscape Planning in Rotterdam by Nico Tillie

“…As part of this research, many functions, flows, areas and actors in the urban landscape system of Rotterdam have been studied. …”
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Assessment of ab initio models of protein complexes by molecular dynamics. by Filip Radom, Andreas Plückthun, Emanuele Paci

“…This is due to the ruggedness of the free-energy landscape, the approximations intrinsic in the scoring functions, and the intrinsic flexibility of proteins. …”
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Characterization of the landscape of the intratumoral microbiota reveals that Streptococcus anginosus increases the risk of gastric cancer initiation and progression by Li Yuan, Libin Pan, Yunzhe Wang, Jing Zhao, Luo Fang, Ying Zhou, Ruihong Xia, Yubo Ma, Zhengchen Jiang, Zhiyuan Xu, Can Hu, Yanan Wang, Shengjie Zhang, Bo Zhang, Haiying Ding, Mengxuan Chen, Haibo Cheng, Ajay Goel, Zhao Zhang, Xiangdong Cheng

“…Here, we integrated multiple types of omics data, including microbiome, transcriptome, and metabolome data, to investigate the functional role of intratumoral bacteria in gastric cancer (GC). …”
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SGK1 drives hippocampal demyelination and diabetes-associated cognitive dysfunction in mice by Ziying Jiang, Bin Liu, Tangsheng Lu, Xiaoxing Liu, Renjun Lv, Kai Yuan, Mengna Zhu, Xinning Wang, Shangbin Li, Song Xu, Xinyu Wang, Yifei Wang, Zhenfang Gao, Peiqing Zhao, Zongyong Zhang, Junwei Hao, Lin Lu, Qingqing Yin

“…More in-depth analysis of oligodendrocytes (OLs) distinguished five subclusters, indicating different functional states of OLs and transcriptional changes in each subcluster. …”
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Altered fecal microbial and metabolic profiles reveal potential mechanisms underlying anemia in patients with chronic renal failure by Haichao Wang, Wen Xue, Jiafen Cheng, Yipei He, Yaxiang Song, Dayong Hu, Ai Peng, Changbin Li, Hui Bao

“…These changes were accompanied by functional alterations in distinctive microbial pathways. …”
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Magnetic ordering phase transition and abnormal brittleness in dilute Fe–Mn solid solution by Wei Liu, Yunfeng Liang, Xiangyan Li, Yichun Xu, Yange Zhang, Wenliang Li, Q.F. Fang, Caetano R. Miranda, Chuan-Lu Yang, C.S. Liu, Xuebang Wu

“…It is noted that the abnormal brittleness might be related to the stress variations resulting from the local Fe–Mn magnetic coupling phase changes within the grains.…”
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The Support Needs of Patients Requesting Medical Aid in Dying and Their Relatives: A Qualitative Study Using Semi-Structured Interviews and Written Narratives by Stijn Vissers, Stijn Vissers, Joni Gilissen, Joni Gilissen, Joachim Cohen, Joachim Cohen, Luc Deliens, Luc Deliens, Freddy Mortier, Freddy Mortier, Freddy Mortier, Kenneth Chambaere, Kenneth Chambaere, Sigrid Dierickx, Sigrid Dierickx

“…We identified eight types of support needs: support for 1) maximizing daily functioning (only reported by patients), 2) making sense of the unbearable suffering (only reported by relatives), 3) managing meaningful activities, 4) navigating existential questions, 5) psycho-emotional regulation, 6) facilitating social interaction, 7) understanding the process toward MAID, 8) and handling organizational and practical matters.ConclusionPatients and relatives might experience multidimensional support needs throughout their MAID trajectories. …”
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Chitosan-based multimodal polymeric nanoparticles targeting pancreatic β-cells by Lorenzo Rossi, Cataldo Pignatelli, Krisztina Kerekes, Francesca Cadamuro, András Dinnyés, Felix Lindheimer, Jochen Seissler, Magdalena Lindner, Sibylle Ziegler, Peter Bartenstein, Yi Qiu, Judit Kovács-Kocsi, Zoltán Körhegyi, Magdolna Bodnár, Erika Fazekas, Eszter Prépost, Francesco Nicotra, Laura Russo

“…Multimodal in vivo imaging of pancreatic islets might improve monitoring of endocrine grafts upon implantation, helping clinical validation of new regenerative therapies based on the replacement of β-cells in type 1 diabetes affected patients. …”
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Sex-based differences in Jumping to Conclusions: a multidimensional analysis of first-episode psychosis by Luciana Díaz-Cutraro, Marina Verdaguer-Rodríguez, Helena García-Mieres, Marta Ferrer-Quintero, Raquel López-Carrilero, Carol Palma-Sevillano, Maria Lamarca, Victoria Espinosa, Mara Luisa Barrigón, Fermín González-Higueras, Esther Pousa, Eva Grasa, Ester Lorente-Rovira, Alfonso Gutiérrez-Zotes, Ana Barajas, Isabel Ruiz-Delgado, Jordi Cid, Steffen Moritz, Julia Rico, Julia Sevilla-Llewellyn-Jones, Josep Maria Haro, Spanish Metacognition Group, Susana Ochoa

“…Logistic regression revealed distinct predictors for JTC by sex: women were influenced by negative internalization of events and visuospatial speed, while men’s JTC was linked to errors in executive functions and memory. These results highlight the importance of sex-specific patterns in JTC and suggest that women might benefit from interventions targeting reflective thinking and social cognition, whereas men may need neurocognitive rehabilitation strategies.…”
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Exposure to the growth promoter tylosin elicits gut microbiota disruption and metabolic imbalance in mouse model by Hongyuhang Ni, Jing Wang, Haoze Wu, Bill Kwan-wai Chan, Kaichao Chen, Han Wang, Edward Wai-Chi Chan, Fuyong Li, Sheng Chen

“…Our findings unveil the detrimental effects of tylosin on animal gut microbiota and metabolic functions and highlight the potential health risks to wildlife and humans when released into the environment. …”
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Temporal correlations between RBD-ACE2 blocking and binding antibodies to SARS-CoV-2 variants in CoronaVac-vaccinated individuals and their persistence in COVID-19 patients by Prapassorn Poolchanuan, Wasin Matsee, Adul Dulsuk, Rungnapa Phunpang, Chakkaphan Runcharoen, Thitiya Boonprakob, Onura Hemtong, Suchada Chowplijit, Vachara Chuapaknam, Tanaya Siripoon, Phimphan Pisutsan, Watcharapong Piyaphanee, Wathusiri Khongsiri, Nathamon Kosoltanapiwat, Le Van Tan, Susanna Dunachie, Chee Wah Tan, Lin-Fa Wang, Wasun Chantratita, Viravarn Luvira, Narisara Chantratita, SEACOVARIANTS

“…Understanding the correlation between binding and functional antibodies is essential to determine whether binding antibody levels can reliably predict neutralizing activity. …”
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NSUN2 lactylation drives cancer cell resistance to ferroptosis through enhancing GCLC-dependent glutathione synthesis by Kaifeng Niu, Zixiang Chen, Mengge Li, Guannan Ma, Yuchun Deng, Ji Zhang, Di Wei, Jiaqi Wang, Yongliang Zhao

“…Lactate-mediated lactylation on target proteins is recently identified as the novel posttranslational modification with profound biological functions. RNA 5-methylcytosine (m5C) modification possesses dynamic and reversible nature, suggesting that activity of its methyltransferase NSUN2 is actively regulated. …”
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Balloon Deflation Strategy during Primary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Clinical Trial and Numeric... by Jun Gu, Yang Zhuo, Tian-jiao Liu, Jie Li, Zhao-fang Yin, Zuo-jun Xu, Li Fan, Qing He, Kan Chen, Hua-su Zeng, Xiao-fei Wang, Yu-qi Fan, Jun-feng Zhang, Fu-you Liang, Chang-qian Wang

“…The change of flow in the balloon-vessel gap and WSS resulted from different balloon deflation velocity might be partly accounted for this results.…”
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LncRNA-HMG incites colorectal cancer cells to chemoresistance via repressing p53-mediated ferroptosis by Zechang Xin, Chenyu Hu, Chunfeng Zhang, Ming Liu, Juan Li, Xiaoyan Sun, Yang Hu, Xiaofeng Liu, Kun Wang

“…Nevertheless, the precise functions of long non-coding RNAs (lncRNAs) in ROS metabolism and tumor drug-resistance remain elusive. …”
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Association between selective serotonin reuptake inhibitors use and blood transfusion risk in older adults after hip fracture: a cohort study by Héloïse Gobillot-Morisson, Bastien Genet, Corinne Frère, Judith Cohen-Bittan, Mathieu Raux, Marie-Eva Rollet, Anthony Meziere, Jacques Boddaert, Lorène Zerah, Sara Thietart

“…Selective serotonin reuptake inhibitors (SSRIs) influence platelet hemostasis and might result in abnormal bleeding. This study aims to determine whether the use of SSRIs in older patients undergoing hip fracture surgery is associated with the risk of perioperative red blood cell (RBC) transfusion. …”
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Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling by Hong Xia, Xue-jiao Tai, Wang Cheng, Yi Wu, Dan He, Li-feng Wang, Hao Liu, Shen-yi Zhang, Yu-ting Sun, Hang-zhi Liu, Dan-dan Liu, Hu-zi Zhao, Fu-yun Ji, Xi-hua Li

“…In summary, the current study revealed that metformin inhibits the growth of SCLC by inducing autophagy and apoptosis via suppression of the EGFR/AKT/AMPK/mTOR pathway. Metformin might be a promising candidate drug for combination therapy of SCLC.…”
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Core prescription pattern of Chinese herbal medicine for depressive disorders in Taiwan: A nationwide population-based study by Diem Ngoc Hong Tran, I-Hsuan Hwang, Fun-Jou Chen, Yuan-Pu Tseng, Ching-Mao Chang, Shih-Jen Tsai, Jen-Lin Yang, Ta-Peng Wu, Chung-Hua Hsu, Fang-Pey Chen, Yen-Ying Kung

“…However, one formula or one single herb might be not show high efficacy when used to treat depression. …”
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