CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions by Lei Huang, Yalei Wen, Qin Guo, Caishi Zhang, Xiao Yang, Mei Li, YiXia Liu, Xinying Li, Jiaxin Tang, Xiaofeng Zhou, Qi Qi, Haoxing Zhang, Tongzheng Liu

“…Collectively, our findings demonstrate the functional significance of the CK2α-DUB3 axis in YAP1 stabilization and YAP1-driven tumor progression, highlighting that strategies to target this axis might be of benefit in the clinical management of ovarian cancer and several other lethal cancers with aberrantly upregulated YAP1.…”
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Ectopic expression of NKG7 enhances CAR-T function and improves the therapeutic efficacy in liquid and solid tumors by Yuxin Chen, Meng Wang, Shuxin Huang, Lulu Han, Ying Cai, Xiaodi Xu, Shuwen Sun, Zhaokai Chen, Junze Chen, Jiatian Yu, Hongwei Du, Huizhong Li, Junnian Zheng, Bo Ma, Gang Wang

“…Here, we applied nineteen individual single-cell RNA sequencing (scRNA-seq) data from clinical samples of digestive cancers to explore the characteristics of tumor-infiltrating T cells (TILs) to identify effective targets which might be benefit for enhancing the function of CAR-T cells. …”
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Current pharmacological and surgical treatment of underactive bladder by Yuan-Hong Jiang, Cheng-Ling Lee, Jia-Fong Jhang, Hann-Chorng Kuo

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Compound exposure of 2.8 GHz and 9.3 GHz microwave causes learning and memory impairment in rats by Liu Sun, Xiaoya Wang, Ke Ren, Chuanfu Yao, Haoyu Wang, Xinping Xu, Hui Wang, Ji Dong, Jing Zhang, Binwei Yao, Xiaohui Wei, Ruiyun Peng, Li Zhao

“…Moreover, disorder of mitochondria and reduced Nissl bodies in hippocampus might contribute to the decrease of cognitive function. …”
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Impact of Severity of Sickle Cell Anemia on Auditory Discrimination Ability and Speech Perception in Noise by Preeti Sahu, Animesh Barman

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Prevalence and family function associated with suicide-related behaviors in vocational college population of southern China: the mediating role of depression by He Wang, Yingyu Zhong, Yueyun Wang

“…Depression played a significant mediating role in the influence of family function on suicide-related behaviors.ConclusionsPoor family function might increase the risk of suicide-related behaviors in vocational school students, and this effect was partly realized by affecting their mental health. …”
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Differential lipids in euthyroid pregnant women with positive TPOAb and its correlation with clinical parameters by Xinxin Chen, Yuxin Qin, Qingyao Wang, Ying Wu, Huanhuan Zang, Xiangguo Cong, Qiong Shen, Lei Chen

“…The pathophysiological role of altered lipid molecules should be further investigated since they might be potential biomarkers for adverse pregnancy outcome in pregnant women with isolated positive TPOAb.…”
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Changes in Respiratory Sensitivity Status of Patients in a Hospital in Shanxi Province Before and After the COVID-19 Epidemic by Dong C, Hu F, Ma Z, Ma X, Zhang L, Li Y, Du X, Feng L, Huo R, Xing Y, Li P, Dong Y, Cheng E, Tian X, Huang M

“…In 2023, the results of pulmonary function tests showed that the positive rate of bronchial provocation/dilatation tests increased (p < 0.001), and the decline in FEV1 during provocation tests became more significant (p < 0.001). …”
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The Effects of Prebiotic Dietary Fibers, Probiotics, and Synbiotics on Gut Permeability and Immunity: A Systematic Review by Leila Maghsoumi-Norouzabad, Alireza Bagherzadeh-Karimi, Shabnam Aliakbari Majd, Leila Hosseini, Fatemeh Shahi

“…Background: Modulation of intestinal barrier, which function through zonulin pathway downregulation, represents a promising therapeutic strategy for chronic diseases. …”
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Safety and efficacy of rotigotine in patients with frontotemporal dementia: a phase 2, double-blind, randomized, placebo-controlled, multicenter trialResearch in context by Giacomo Koch, Martina Assogna, Yasmine Gadola, Antonella Alberici, Francesco Di Lorenzo, Sonia Bonnì, Ilaria Borghi, Emanuele Cerulli Irelli, Lucia Mencarelli, Michele Maiella, Romina Esposito, Elias Paolo Casula, Valentina Pezzopane, Alessia D'Acunto, Francesca Candeo, Matteo Ferraresi, Gisella Guerrera, Luca Battistini, Enrico Premi, Valeria Bracca, Silvia Lucchini, Francesco Bertagna, Pasquale Romano, Andrea Ludovici, Antonio Daniele, Caterina Motta, Clarissa Ferrari, Alessandro Martorana, Barbara Borroni

“…Interpretation: Rotigotine administration may not be a viable therapeutic option for enhancing frontal function, slowing disease progression, mitigating functional decline or ameliorating behavioral disturbances in bvFTD patients. …”
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Functional Annotation of Uncharacterised Proteins Whose Expression Patterns Affect the Lifespan under Metformin Treatment in Fission Yeast by Çağatay Tarhan, Sümeyra Zeynep Çalıcı, Buse Özden

“…Thus, bioinformatic analyses that might direct experimental studies are crucial. Moreover, uncharacterised proteins with unknown molecular functions might withhold information regarding metformin’s mode of action. …”
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Frontal Cognitive Function and Memory in Parkinson’s Disease: Toward a Distinction between Prospective and Declarative Memory Impairments? by A. I. Tröster, J. A. Fields

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SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function. by Courtney Anderson, Shan Zhou, Emma Sawin, H Robert Horvitz, Michael E Hurwitz

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Genetic evidence suggests a causal relationship linking thyroid function to prospective memory and dementia and Parkinson’s disease by Yang Wang, Yanying Liu, Huimin Yang, Zhuang Mo, Haiyan Liu, Qi Yu

“…Abstract Epidemiological studies suggest a link between thyroid function and prospective memory (PM), but more evidence is required. …”
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Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences by Shih‐Ching Chang, Yuan‐Tzu Lan, Pei‐Ching Lin, Shung‐Haur Yang, Chien‐Hsing Lin, Wen‐Yi Liang, Wei‐Shone Chen, Jeng‐Kai Jiang, Jen‐Kou Lin

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Effects of childhood trauma on sustained attention in major depressive disorder: the mediating role of brain activity and functional connectivity by Mingfeng Lai, Ping Jiang, Peiwei Xu, Dan Luo, Wenxin Bao, Jing Li, Jiajun Xu

“…Conclusion The fALFF in PoCG.L, and FC of PoCG.L-PreCG.L and ANG.L-STG.R might be potential neural substrate in the association between the childhood trauma and poor sustained attention in the MDDs, and might serve as potential intervention targets for the treatment of sustained attention deficits in MDDs with childhood trauma history.…”
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Clinical and functional reasons for internal thoracic artery Novocain blocks during in-patient coronary heart disease treatment by I. A. Latfullin, I. V. Bilalov, R. R. Bilalova

“…Aim. Clinical and functional prove for using of modified Novocain block of internal thoracic arteries during inpatient coronary heart disease (CHD) treatment. …”
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Blood pressure improvement after resection of non-functioning adrenal adenomas: influencing factors and serum metabolic features by Jianlei Zhang, Peiqiang Wu, Yule Chen, Min Wang, Wenbin Song

“…IntroductionNon-functioning adrenal adenomas (NFAs) are typically regarded as benign tumors that lack hormonal secretion. …”
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Applying the International Classification of Functioning, Disability and Health in establishing a rehabilitation diagnosis for patients with juvenile myoclonic epilepsy by K. V. Petrov, E. Yu. Mozheyko, N. A. Shnayder, M. M. Petrova, E. A. Narodova

“…It provides better insight into a range of difficulties patients with JME might face at the level of personal health and in everyday life.…”
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Longitudinal relationships between pet ownership and cognitive functioning in later adulthood across pet types and individuals’ ages by Adriana Rostekova, Charikleia Lampraki, Jürgen Maurer, Clément Meier, Maud Wieczorek, Andreas Ihle

“…Abstract Pet ownership has been shown to have a positive influence on cognitive functioning and cognitive decline in late adulthood. …”
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