Heterologous Overexpression of Cytochrome P450BM3 from <i>Bacillus megaterium</i> and Its Role in Gossypol Reduction by Wenpeng Fan, Jingjing Cui, Tongxiang Xu, Shiheng Xu, Zulibina Ainiwaer, Qiyu Luo, Caidie Wang

“…To determine whether the candidate cytochrome P450BM3 enzymes could reduce gossypol in vitro, functional recombinant cytochrome P450BM3 enzymes were successfully expressed in <i>E. coli</i>. …”
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Single nucleotide polymorphisms of GYS2 gene and its association with milk production traits of dairy cows by Wen Ye, Ao Chen, Lingna Xu, Dongxiao Sun, Bo Han

“…Furthermore, 5:g.88602007G > A and 5:g.88602026G > A were predicted to change the transcription factor binding sites (TFBSs), which might regulate the expression of GYS2. The missense mutation site, 5:g.88602535G > T, changed the secondary structure of mRNA and the secondary and tertiary structure of protein. …”
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Lactic acid bacteria reduce the toxicity of tetrodotoxin through peptidoglycan mediated binding by Chang Liu, Jingqin Ye, Chang'e Wang, Hengliang Wang, Ying Lu

“…These results suggested that the amino and carboxyl groups of PGs were important action sites for the binding interaction between LAB and TTX, and electrostatic interaction might be one of the ways of binding between PG and TTX. …”
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Increased organic fertilizer significantly increases leaf nitrogen and phosphorus but not carbon content in a tropical tea plantation by Jing-li Lu, Ying Wang, Di Li, Qiu Yang, Yamin Jiang, Peng Wang, Tianyan Su, Geming Li, Qian Shi, Huai Yang, Wenjie Liu, Mengyang Fang

“…Abstract Carbon (C), nitrogen (N), and phosphorus (P) are essential elements for plant growth and metabolism, with their stoichiometry playing a pivotal role in ecosystem functioning. In tea plantations, fertilization strongly influences the balance of these elements. …”
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The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication by Toma Gruica

“…Funding models must evolve beyond traditional reimbursement schemes ill-fitted to support the sustained maintenance and upgrading necessary for BCI functionality. Innovative approaches might include insurance categories recognizing “communicative benefit,” public-private consortia dedicated to maintenance, or endowment funds ensuring long-term support. …”
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Genome-Wide Identification, Phylogeny, and Expression Analysis of ARF Genes Involved in Vegetative Organs Development in Switchgrass by Jianli Wang, Zhenying Wu, Zhongbao Shen, Zetao Bai, Peng Zhong, Lichao Ma, Duofeng Pan, Ruibo Zhang, Daoming Li, Hailing Zhang, Chunxiang Fu, Guiqing Han, Changhong Guo

“…Moreover, 15 pairs of PvARFs have different temporal-spatial expression profiles in vegetative organs (2nd, 3rd, and 4th internode and leaves), which implies that different PvARFs have specific functions in switchgrass growth and development. In addition, at least 14 pairs of PvARFs respond to naphthylacetic acid (NAA) treatment, which might be helpful for us to study on auxin response in switchgrass. …”
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Unveiling kaempferol glycosides as the key antiglycative components in butterfly pea (Clitoria ternatea) flower by Jun Wu, Jun Gong, Qiaochun Chen, Wen Hao, Jiayi He, Mingfu Wang, Qian Zhou

“…Collectively, our findings highlight the beneficial effects of BFPF with clearly identified active components, which might further promote its application in functional food and medical industry.…”
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The evolution of superbugs in space: a genomic perspective on pathogens in the International Space Station environment by Sara Pearl, Hithesh Kumar, Santhiya Vijayakumar, Soumya Basu, Sudha Ramaiah, Anand Anbarasu

“…The presence of hypervirulent and antibiotic-resistant pathogens in space station is a worrisome feature as these might cause serious life-threatening infections in astronauts staying in high stress environments with weakened immune systems. …”
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Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health by Fernanda Aparecida dos Santos France, Debora Kazumi Maeda, Ana Beatriz Rodrigues, Mai Ono, Franciele Lopes Nogueira Marchetti, Marcos Martins Marchetti, Allana Cristina Faustino Martins, Roberto da Silva Gomes, Cláudia Aparecida Rainho

“…The molecular docking simulations indicate that these fatty acids might interact with class I HDACs, specifically with the catalytic domain of human HDAC2, likewise well-known HDAC inhibitors (HDACi) such as SAHA (suberoylanilide hydroxamic acid) and TSA (Trichostatin A). …”
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Green synthesis and characterization of CuO/ZnO nanocomposite using Musa acuminata leaf extract for cytotoxic studies on colorectal cancer cells (HCC2998) by Wong Yee Jin, Subramaniam Hemaroopini, Shing Wong Ling, Dhanapal Anto Cordelia Tanislaus Antony, Chan Yu Bin, Aminuzzaman Mohammod, Tey Lai-Hock, Janakiraman Ashok Kumar, Kayarohanam Saminathan, Djearamane Sinouvassane

“…The synthesis of nanocomposite (NC) has attracted the attention of researchers, as its synergistic effect might enhance its effectiveness in anticancer to overcome multidrug resistance. …”
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Cooperative mechanisms of LexA and HtpG in the regulation of virulence gene expression in Pseudomonas plecoglossicida by Rongchao He, Yanfei Zuo, Qiu Li, Qingpi Yan, Lixing Huang

“…Our previous research suggested that LexA might collaboratively regulate virulence gene expression with HtpG during infection. …”
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Single-cell RNA sequencing integrated with bulk RNA sequencing analysis of clock circadian regulator with prognostic and immune microenvironment in thyroid cancer by Zhen shen, Yuelei Zhao, Xinxin Xu, Huini Yang, Shuting He, Junchi Ma, Shaoqiang Zhang, Peng Hou, Fang Sui

“…Besides, analyses of gene enrichment, signaling pathways, and immune checkpoints suggested that CLOCK might inhibit immune infiltration within the tumor microenvironment. …”
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Abstract 229: Recanalization Rate in Mechanical Thrombectomy in Patients With Elevated LDL‐C Levels by Xiaoyi Gao, Kara Christopher, Wilson Rodriguez, Weston Gordon, Guillermo Linares

“…This association we observed might explain the relationship between good functional outcomes and elevated LDL‐C levels found in our study and the previous studies. …”
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Exploring Technical Features to Enhance Control in Videoconferencing Psychotherapy: Quantitative Study on Clinicians’ Perspectives by Francesco Cataldo, Shanton Chang, Antonette Mendoza, George Buchanan, Nicholas Van Dam

“…An earlier study provided a set of potential features that may help enhance psychologists’ control in their videoconference sessions, such as screen control functionality, emergency call functionality, eye contact functionality, zooming in and out functionality, and an interactive interface with other apps and software. …”
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circRNA circ_102049 Implicates in Pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p by Jie Zhu, Yong Zhou, Shanshan Zhu, Fei Li, Jiajia Xu, Liming Zhang, Hairong Shu

“…Mechanistically, circRNA_102049 functioned as a sponge of miR-455-3p and partially reversed the effect of miR-455-3p and consequently upregulated CD80 expression. …”
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Exploring the Determinants of Physical and Mental Health among Patients with Non Specific Chronic Low Back Pain and Movement Control Impairment: A Cross-sectional Study by Manju Kaushik, Irshad Ahmad

“…Relatively, fear of movement had a significant impact on physical health and functional disability had an impact on mental health. …”
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Altered Amplitude of Low-Frequency Fluctuations in Inactive Patients with Nonneuropsychiatric Systemic Lupus Erythematosus by Yang Yu, Liheng Chen, Qiaohong Wang, Lingzhen Hu, Qiuping Ding, Xize Jia, Xuyan Yang

“…Abnormal low-frequency oscillations in multiple brain regions were found in inactive patients with non-NPSLE, indicating that the alteration of mALFF, PerAF, and mPerAF in specific brain regions might be an imaging biomarker of brain dysfunction in inactive patients with non-NPSLE.…”
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Effects of pH/<i>p</i>CO₂ fluctuations on photosynthesis and fatty acid composition of two marine diatoms, with reference to consequences of coastal acidification by Y. Shang, J. Qiu, Y. Weng, X. Wang, D. Zhang, Y. Zhou, J. Xu, J. Xu, F. Li, F. Li

“…Together with the altered nutritional quality of prey for higher trophic levels, coastal acidification might have far-reaching consequences for marine ecosystem functioning.…”
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Identification of lncRNA biomarkers in lung squamous cell carcinoma using comprehensive analysis of lncRNA mediated ceRNA network by Rui Li, Yi-E Yang, Jia Jin, Meng-Yu Zhang, Xiao Liu, Xiao-Xia Liu, Yun-Hong Yin, Yi-Qing Qu

“…In conclusion, CeRNAs contributed to the progression of LUSC and a model with 6 lncRNAs might be potential biomarker for predicting the prognosis of LUSC.…”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…Background: Transcutaneous vagus nerve stimulation (tVNS) has emerged as a promising technique to modulate autonomic functions, and pupil dilation has been recognized as a promising biomarker for tVNS-induced monoaminergic release. …”
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