Construction of a novel five programmed cell death-related gene signature as a promising prognostic model for triple negative breast cancer by Quanfeng Shao, Hai-yan Gao, Zi-ying Wang, Yu-ling Qian, Wei-xian Chen

“…Gene set enrichment analysis was carried out to investigate the pathways and molecular functions. Results Five PCD-related genes including SEPTIN3, SCARB1, CHML, SYNM, and COL5A3 were identified to establish the PCD-related risk score for TNBC patients. …”
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Glycodelin is a potential biomarker for malignant tumors by M. V. Mnikhovich, M. A. Shekhter, T. V. Bezuglova, K. Kh. Skafi, K. A. Artemyeva, E. S. Mishina

“…On the other hand, glycodelin might play a role in neovascularisation, thereby promoting tumor growth. …”
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Persistent Helicobacter pylori specific Th17 responses in patients with past H. pylori infection are associated with elevated gastric mucosal IL-1β. by Victoria Serelli-Lee, Khoon Lin Ling, Cassandra Ho, Lai Han Yeong, Gek Keow Lim, Bow Ho, Soon Boon Justin Wong

“…We speculate that this persistent inflammation might contribute to gastric mucosal pathology, for example, persistent increased gastric cancer risk despite eradication of HP.…”
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Usutu virus NS4A induces autophagy and is targeted by the selective autophagy receptor p62/SQSTM1 for degradation by Tessa Nelemans, Ali Tas, Nina L. de Beijer, George M. C. Janssen, Peter A. van Veelen, Martijn J. van Hemert, Marjolein Kikkert

“…P62 thus plays an antiviral role during USUV infection, although this antiviral effect might also be related to its functions outside the autophagy pathway, such as modulation of the immune response. …”
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Exploring urban garden ponds: considering chemical pollution as a limiting factor for insect diversity in cities by Johanna Bock, Marie Neske, Martin Krauss, Andrea Dombrowski, Jörg Oehlmann

“…Abstract Background Insects are experiencing a drastic biodiversity and biomass decline while providing important ecosystem functions. Therefore, it is of great concern to further uncover underlying causes, with the goal of identifying mechanisms to dampen biodiversity loss. …”
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La pupilometría en el socorrismo acuático profesional: la vigilancia como factor determinante del ahogamiento (The use of pupillometry in aquatic lifesaving: vigilance as a key fac... by Sergio López García, María Inmaculada Martín Villar, José Antonio Navia Manzano, José Enrique Moral García, Mario Amatria Jiménez, Rubén Maneiro Dios, Cristian Abelairas Gómez

“…Lifeguards are entrusted with three main functions: prevention, surveillance, and intervention. …”
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Landscape analysis of matrix metalloproteinases reveals key prognostic markers for prostate cancer by Wei Li, Xi Wei, Ying Yu, Yuan Tian, Qi Yu, Jun Qiao, Yuewei Tao, Yanfeng Li, Tao Li

“…Noteworthy, we further proved that MMP11 significantly promoted PCa probably through reprogramming of tumor microenvironment, which might provide a promising-target for PCa treatment.…”
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Potential Association of Gut Microbial Metabolism and Circulating mRNA Based on Multiomics Sequencing Analysis in Fetal Growth Restriction by Hui Tang, Dan Li, Jing Peng, Weitao Yang, Xian Zhang, Hanmei Li

“…Metabolites such as aspartic acid, methionine, alanine, L-tryptophan, 3-methyl-2-oxovalerate, and ketoleucine showed notable functional alterations. Spearman correlation analysis indicated that metabolites like methionine and alanine, microbiota (Tyzzerella), and circulating mRNA (TRIM34, SMOX, FAM83A, NAPG) might play a role as mediators in the communication between the gut and circulatory system interaction in FGR. …”
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Annona squamosa (custard apple) leaves extract mitigates abemaciclib-induced liver injury (AILI) in male rats by Lashin S. Ali, Gamal Mohamed, Ahmed A. El-Mansy, Khaled S. El-Bayoumi, Mohammed Y. Sobhey, Abd El-Fattah B. M. El-Beltagy, Reham A. Ghanem

“…Abemaciclib-induced liver injury (AILI) is a significant concern in clinical practice, since it may need dose reduction or withdrawal of abemaciclib and might impact following therapy options. Annona squamosa is a medicinal plant that produces edible fruits, usually referred to as the sugar apple. …”
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Molecular basis identification and hypnotic drug interactions for cognitive impairment related to sleep deprivation by Shun Zeng, Nannan Liu, Andong Zhang, Na Duan, Bo Xu, Chunqi Ai

“…The GEO2R tool, Robust rank aggregations, and Venny were used to retrieve the common DEGs. Functional gene and pathway analyses were carried out via GO and the KEGG analyses. …”
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Identification of Staphylococcus aureus virulence-modulating RNA from transcriptomics data with machine learning by Jinlong Yu, Mingzhang Li, Jin Wang, Musha Hamushan, Feng Jiang, Boyong Wang, Yujie Hu, Pei Han, Jin Tang, Geyong Guo, Hao Shen

“…TCSs have been well studied over the past several decades, but our understanding of sRNA functions lags far behind that of TCS functions. Here, we studied the biological role of sRNA from 506 S. aureus RNA-seq datasets using independent component analysis (ICA). …”
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PPARβ/δ prevents inflammation and fibrosis during diabetic cardiomyopathy by Adel Rostami, Xavier Palomer, Javier Pizarro-Delgado, Emma Barroso, Brenda Valenzuela-Alcaraz, Fátima Crispi, J. Francisco Nistal, María A. Hurlé, Raquel García, Walter Wahli, Manuel Vázquez-Carrera

“…Overall, the data suggest that PPARβ/δ agonists might be useful in preventing inflammation and fibrosis progression in DCM.…”
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LGBT Actors, Ritual and Martial Arts Groups, and State-Building in Post-Conflict Timor-Leste by Lili Chen, Laura Sjoberg

“…Our beginnings of this rethinking suggest that looking more broadly at these groups’ gender dynamics and (therefore) at their scope and function provides the ability to see them not only as more than violent, but as actors that do community-building and state-building work. …”
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miR-210 loss leads to widespread phenotypic and gene expression changes in human 293T cells by Xiaoxiao Zhang, Zhen Meng, Chengyong Yang, Chenghao Wang, Kexin Zhang, Anxin Shi, Jingjing Guo, Yong Feng, Yan Zeng

“…In particular, we showed that miR-210 might target the expression of BNIP3L as a potential mechanism to suppress apoptosis. …”
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Comparative analysis of the NF-Y transcription factor family identifies VaNF-YA6 as a positive regulator of salt and drought tolerance in grapevine by Shixiong Lu, Xueting Zhou, Xu Huang, Baozhen Zeng, Huimin Gou, Weifeng Ma, Zonghuan Ma, Juan Mao, Baihong Chen

“…Interestingly, the NF-YA protein sequence of ‘NTKKLDWEFWGCCDDCEKWFGGCC’ was lost in the V. vinifera compared to V. amurensis, whereas the sequence ‘SSVYSQPWWGHSIVCVA’ was gained, thus, these sequences might be closely related to the functions performed. …”
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Effects of different climatic conditions on soil water storage patterns by A. Ehrhardt, A. Ehrhardt, J. Groh, J. Groh, J. Groh, H. H. Gerke

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Meta-analysis of proteomics data from osteoblasts, bone, and blood: Insights into druggable targets, active factors, and potential biomarkers for bone biomaterial design by Johannes R Schmidt, Klaudia Adamowicz, Lis Arend, Jörg Lehmann, Markus List, Patrina SP Poh, Jan Baumbach, Stefan Kalkhof, Tanja Laske

“…To address this, our proteomic meta-analysis aims to identify universally affected proteins and functions in the context of bone regeneration that can be utilized as novel bioactive biomaterial functionalizations, drug targets or therapeutics as well as analytical endpoints, or biomarkers in implant design and testing, respectively. …”
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Serum IgG antibodies against Helicobacter pylori low molecular weight antigens 50kDa, 30kDa and Urease A 26 kDa, along with vacuolating cytotoxin A are associated with the outcome... by Manojlović Nebojša, Tufegdžić Ivana, Ristanović Elizabeta, Bokonjić Dubravko

“…The Western blot test was performed in 123 patients, 31 with gastric cancer, 31 with duodenal ulcer, 31 with gastric ulcer, 30 with gastritis and functional dyspepsia in order to determine IgG antibodies to H. pylori antigens (CagA, VacA, Heat shock protein 60kDa, Urease B 66 kDa, Flagellin 55kDa, 50kDa, 30 kDa, Urease A 26 kDa, 24 kDa). …”
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Multi-directional deformation for coordinating isotropy and strength-ductility synergy in a CoCrNi alloy by Na Lin, Zhicheng Miao, Mingcan Li, Rumeng Huang, Kaiyuan Zheng, Zhaowen Huang, Donghui Wen, Cong Zhang, Anding Wang

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Global quantitative proteome analysis of a multi-resistant Klebsiella pneumoniae strain by Marie-Sofie Illenseher, Marie-Sofie Illenseher, Christian Hentschker, Manuela Gesell Salazar, Larissa Milena Busch, Lisa Zierke, Alexander Reder, Stephan Michalik, Uwe Völker, Sven Hammerschmidt, Kristin Surmann

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