The effect of chronic, non-specific low back pain on superficial lumbar muscle activity: a protocol for a systematic review and meta-analysis by Alison B Rushton, Nicola R Heneghan, Deborah Falla, Andy Sanderson, Eduardo Martinez Valdes, Alessio Gallina

“…Introduction Chronic, non-specific low back pain is a major global cause of disability. One factor which might potentially contribute to ongoing pain is maladaptive variation in the level of activity in the lumbar musculature. …”
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Deciphering the role of dietary modifications and gut dysbiosis in Non-Alcoholic Fatty Liver Disease by Meenakshi Vachher, Kohinoor Kaur, Manisha Marothia, Archana Burman, Deepanjana, Savita Bansal

“…Dietary alterations or nutritional interventions have a huge impact on gut microbiota composition and functions. An association between the type of diet, altered gut microbiota, and NAFLD is now being appreciated. …”
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LncRNA IGF2-AS serves as a miR-106b-5p sponge to induce apoptosis and inflammatory reaction of bronchial epithelial cells in COPD by Ming Yao, Yanshun Wei, Meng Ai, Haiyan Chen, Yajie Jia, Lu Zhang, Lan Ni

“…Aim This study evaluated the clinical role of serum lncRNA IGF2-AS in stable COPD and AECOPD and explored its functional mechanism in bronchial epithelial cells. …”
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Effect of Raphanus sativus L. var. sativus on Bakery Quality by Anastasia V. Paymulina, Olga V. Golub, Galina P. Chekryga, Oleg K. Motovilov, Pavel V. Semenov

“…The research expanded the knowledge about non-traditional plant ingredients in functional bakery.…”
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Secretagogin Mediates the Regulatory Effect of Electroacupuncture on Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Surgical Trauma by Mizhen Zhang, Jingxian Sun, Yu Wang, Zhanzhuang Tian

“…We hypothesized that SCGN in the PVN might trigger the HPA system and be involved in EA-mediated modulation of HPA dysfunction caused by surgical trauma. …”
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Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer by Lu Chen, Yuting Xia, Liangliang Min, Yuqin Zhang, Da Huang, Yulu Zhang, Aihua You, Zhihua Li

“…Network pharmacology and molecular docking were used to determine the targets for sophoridine in breast cancer, and confirmed by molecular dynamics simulation and CETSA-western blot assay. Additionally, the functional rescue and signaling pathway regulated by sophoridine was analyzed.Results Sophoridine suppressed the proliferation, migration, and invasion of breast cancer cells. …”
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Growth Patterns of Reef-Building <i>Porites</i> Species in the Remote Clipperton Atoll Reef by Ania Ochoa-Serena, J. J. Adolfo Tortolero-Langarica, Fabián A. Rodríguez-Zaragoza, Juan P. Carricart-Ganivet, Eric Clua, Alma P. Rodríguez-Troncoso

“…Recognizing the coral species’ growth response might help understand ecological dynamics and the impacts of anthropogenic stressors on coastal reefs. …”
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Multi-omics analysis reveals the core microbiome and biomarker for nutrition degradation in alfalfa silage fermentation by Yuan Wang, Yunlei Sun, KeXin Huang, Yu Gao, Yufan Lin, Baojie Yuan, Xin Wang, Gang Xu, Luiz Gustavo Nussio, Fuyu Yang, Kuikui Ni

“…However, the detailed microbial components and their functions in silage fermentation are not fully understood. …”
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Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

“…Treatment decision and delivery times, early neurological recovery and day 90 functional outcomes did not differ significantly between groups. …”
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Regionally Specific Regulation of Sensorimotor Network Connectivity Following Tactile Improvement by Stefanie Heba, Melanie Lenz, Tobias Kalisch, Oliver Höffken, Lauren M. Schweizer, Benjamin Glaubitz, Nicolaas A. J. Puts, Martin Tegenthoff, Hubert R. Dinse, Tobias Schmidt-Wilcke

“…We investigated which areas in the sensorimotor network are susceptible to neural plasticity (i.e., where changes in functional connectivity occurred) and where iFC might be indicative of enhanced tactile performance. …”
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Surface microlayer-mediated virome dissemination in the Central Arctic by Janina Rahlff, George Westmeijer, Julia Weissenbach, Alfred Antson, Karin Holmfeldt

“…From the 1154 viral operational taxonomic units (vOTUs), of which two-thirds were predicted bacteriophages, 17.2% encoded for auxiliary metabolic genes (AMGs) with metabolic functions. Some AMGs like glycerol-3-phosphate cytidylyltransferase and ice-binding like proteins might serve to provide cryoprotection for the host. …”
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klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. by Peter Novodvorsky, Oliver Watson, Caroline Gray, Robert N Wilkinson, Scott Reeve, Carl Smythe, Richard Beniston, Karen Plant, Richard Maguire, Alexander M K Rothman, Stone Elworthy, Fredericus J M van Eeden, Timothy J A Chico

“…Targeted genome editing is an increasingly applied method for functional assessment of candidate genes. We therefore generated a stable klf2a mutant zebrafish and characterised its cardiovascular and haematopoietic development.…”
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The meaning of “total pain” in the context of living and dying with dementia by Sarah Elizabeth Field-Richards, Louise Bramley, Jemima Collins, Alison Cowley, Rowan Harwood

“…The holistic focus of “total pain” should be extended to incorporate balanced consideration of “painful” and “functional” experience. We introduce a balanced model of total pain incorporating a dual focus on “pain” and “personhood” within a critical context, to facilitate translation to practice. …”
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Isospin competitions and valley polarized correlated insulators in twisted double bilayer graphene by Le Liu, Shihao Zhang, Yanbang Chu, Cheng Shen, Yuan Huang, Yalong Yuan, Jinpeng Tian, Jian Tang, Yiru Ji, Rong Yang, Kenji Watanabe, Takashi Taniguchi, Dongxia Shi, Jianpeng Liu, Wei Yang, Guangyu Zhang

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Meta-Analysis of Tai Chi Chuan in Treating Lumbar Spondylosis and Back Pain by Fushun Zhang, Junfang Zhao, Nan Jiang, Qiao Zhai, Juanjuan Hu, Jing Zhang

“…Our results indicate that Tai Chi individually or with additional treatment along with routine physical exercises might reduce the pain and functional disorders for the patients suffering from back pain.…”
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Assessment of the TGF-β gene and its target miR-1908-5p gene expression and its role in the treatment of beta-thalassemia in Iraqi patients by Manal Lafta Abdulhassn, Hiba Muneer Abdel Hassan Al-Khafaji, Maryam Qasim Mohammed

“…Transforming growth factor-beta (TGF-β) is a cytokine that has multicellular functions. The miRNAs have been confirmed to play important roles in gene expression regulation during the development of a variety of human diseases. …”
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Identification and validation of oxidative stress-related genes for the diagnosis of sepsis-induced acute lung injury. by Xue Fu, Jiawei Dong, Jian Yang, Xiaotian Zhang, Sen Wang, Shangkun Cai, Yiwei Zhang, Meng Zhang

“…The logistic regression model developed using these six genes could identify patients with sepsis-induced ALI. Our findings might provide novel research strategies for the molecular therapeutic target of sepsis-induced ALI.…”
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Antioxidants, oxidative stress and reactive oxygen species in insects exposed to heat by Daniel González-Tokman, Sebastián Villada-Bedoya, América Hernández, Bibiana Montoya

“…Potential trade-offs between antioxidant use to different functions could define insect survival and pace of life in response to multiple stressors, including high temperatures. …”
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LA MODALIDAD EPISTÉMICA ASERTIVA COMO RECURSO RETÓRICO EN NOTICIAS CIENTÍFICAS: EL CASO DEL HALLAZGO PALEONTOLÓGICO DEL HOMBRE DE ORCE by José Antonio Díaz Rojo

“…The discovery of a small skull fragment was initially attributed to the oldest hominoid found in Eurasia, yet later analyses indicated that it might really be from an equidae. I describe linguistic forms of the lexical type, the semantic contents (credibility, verification, conviction and confirmation) as well as the social and epistemological rhetorical functions of modalizers such as tajantemente, verificaci&amp;oacute;n, cre e r, ratificar, poder afirm a r. …”
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Neuromonitoring modalities predicting neurological impairment in pediatric congenital heart disease: a systematic review by Liselotte Van Loo, Liselotte Van Loo, Bjorn Cools, Bjorn Cools, Anneleen Dereymaeker, Anneleen Dereymaeker, Katrien Jansen, Katrien Jansen

“…This systematic review reports on the utility of three functional neuromonitoring modalities, Near-infrared Spectroscopy (NIRS), electroencephalography (EEG) and biochemical biomarkers, in predicting either clinical neurodevelopmental outcome or structural brain abnormalities after pediatric CHD surgery. …”
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