Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat by Jean Pierre Munyaneza, Minjun Kim, Eunjin Cho, Aera Jang, Hyo Jun Choo, Jun Heon Lee

“…Interestingly, two candidate genes (GPNMB and SFRP1) were reported to regulate the expression of genes known to be involved in fatty acid synthesis, such as the FASN, ACACA, ACLY, ELOVL, and SCD genes. Identification of functional candidate genes for fatty acid profiles might facilitate the selection and breeding of chickens with desirable and healthier fatty acids. …”
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The Long-Term Clinical and Radiographic Outcomes of Cerclage Cable Fixation for Displaced Acetabular Fractures Using a Posterior Approach: A Retrospective Cohort Study by Yutaro Kuwahara, Genta Takemoto, So Mitsuya, Ken-ichi Yamauchi

“…<i>Background and Objectives</i>: Cerclage cable fixation with 2 mm multiple-braided cables for displaced acetabular fractures has shown good midterm functional and radiographic outcomes. We retrospectively evaluated the clinical and radiographic outcomes of cerclage cable fixations over ten years. …”
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Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells by Jun-Hui Guo, Ali Afzal, Ali Afzal, Sadia Ahmad, Ghazala Saeed, Amna Rehman, Umair Ali Khan Saddozai, Umair Ali Khan Saddozai, Lei Liu, Shi-Hao Guo, Xin-Ying Ji, Xin-Ying Ji, Muhammad Babar Khawar, Muhammad Babar Khawar, Muhammad Babar Khawar

“…While immunotherapy faces obstacles, the emergence of chimeric antigen receptor (CAR) engineered natural killer (NK) cells is paving new ways and might become a preferred option over CAR T cells very soon. …”
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Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway by Hui Yang, Wei Sun, Yan-nan Fan, Shu-yi Li, Ji-qiao Yuan, Zi-qian Zhang, Xu-yu Li, Ming-bao Lin, Qi Hou

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Study on factors affecting fruit development of seedless ponkan cultivar Huagan No.4 by LIU Chenglang, LI Gangqiu, LI Shunxin, WEI Ranran, LU Yan, CHENG Chao, TANG Zheng, LIU Baoyan, YE Junli, CHAI Lijun, DENG Xiuxin, XIE Zongzhou

“…[Conclusion] The low expression of hormone metabolic pathway genes affected hormone contents in HG4 fruits during early development period, which might lead to the inherent causes of smaller fruits. …”
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Breeding Biology, Chronology, and Reproductive Success of the European Serin (Serinus serinus) at Moulouya High Plain (Morocco) by Ismail Mansouri, Wafae Squalli, Mohamed Dakki, Amine Assouguem, Abdelbari El Agy, Abderahim El Hassani, Chaimae Belarbi, Youssef Dbiba, Hassnae Kouali, Lahsen El Ghadraoui

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Auricularia polytricha noodles prevent hyperlipemia and modulate gut microbiota in high-fat diet fed mice by Donglu Fang, Dan Wang, Gaoxing Ma, Yang Ji, Huihua Zheng, Hui Chen, Mingwen Zhao, Qiuhui Hu, Liyan Zhao

“…Auricularia polytricha possesses hypolipidemic effects and decreases lipid accumulation, leading to potential food additives for functional food processing. In this research, we explored the potential effects of A. polytricha noodles on hyperlipidemia and gut microbiota dysbiosis, and elucidated their possible regulatory mechanisms on lipid metabolism in high-fat diet (HFD) mice. …”
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Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons by Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst

“…Thus, the AAV‐dCAS approach might enable an alternative route for clinical therapies of Parkinson's disease.…”
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Selective Serotonin Reuptake Inhibitors and Risk of Gastrointesinal Bleeding In Dyspepsia: An Evidence-Based Case Report by Hamzah Shatri, Steven Zulkifly, Rudi Putranto, Dadang Makmun, Achmad Fauzi, Hasan Maulahela, Edward Faisal, Vinandia Irvianita, Yanuar Ardani

“…All studies showed SSRIs did not increase the risk of GI bleeding in patients with functional dyspepsia and peptic ulcer. However, the adverse event of SSRIs might be under-reported. …”
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Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury by K. Taylor, R. Ram, R. Ram, L. Ewart, C. Goldring, G. Russomanno, G. P. Aithal, T. Kostrzewski, C. Bauch, J. M. Wilkinson, J. M. Wilkinson, S. Modi, J. G. Kenna, J. G. Kenna, J. Bailey, J. Bailey

“…Predicting which drugs might have the potential to cause drug-induced liver injury (DILI) is highly complex and the current methods, 2D cell-based models and animal tests, are not sensitive enough to prevent some costly failures in clinical trials or to avoid all patient safety concerns for DILI post-market. …”
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Near-Infrared Synaptic Responses of WSe₂ Artificial Synapse Based on Upconversion Luminescence from Lanthanide Doped Nanoparticles by Yaxian Lu, Chuanwen Chen, Qi Sun, Ni Zhang, Kun Lv, Zhiling Chen, Yuelan He, Haowen Tang, Ping Chen

“…Biological synaptic functions were simulated successfully through 975 nm laser regulation, including paired-pulse facilitation (PPF), spike rate-dependent plasticity, and spike timing-dependent plasticity. …”
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Development and optimization of a neural network model using genetic algorithm to predict the performance of a packed bed reactor treating sulphate-rich wastewater by Manoj Kumar, Rohil Saraf, Shishir Kumar Behera, Raja Das, Mansi Aliveli, Arindam Sinharoy, Eldon R. Rene, Ravi Krishnaiah, Kannan Pakshirajan

“…Using genetic algorithm (GA) with appropriate objective functions, optimal sets of inputs were obtained to ensure maximum RE at a minimum HRT. …”
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Effect of legacy and emerging pollutants on genome-wide methylation patterns in black hake (Merluccius polli) natural populations by Carmen Blanco-Fernandez, María Bobes-Villa, Ainhoa López, Daniel Menéndez, Kathryn R. Elmer, Eva Garcia-Vazquez, Gonzalo Machado-Schiaffino

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Quality of Life of Long-Term Hemodialysis Patients by A. E. Khrulev, E. S. Kudryavtseva, P. A. Egorova, A. D. Rodionova, S. N. Sorokoumova, O. V. Suvorova

“…In PHD patients, the physical health component is the one that suffers most of all, namely: physical functioning, role functioning related to physical condition, pain intensity, and general health condition. …”
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The Interplay between Liver and Adipose Tissue in the Onset of Liver Diseases: Exploring the Role of Vitamin Deficiency by Ivan Tattoli, Aimee Rachel Mathew, Antonella Verrienti, Lucia Pallotta, Carola Severi, Fausto Andreola, Virve Cavallucci, Mauro Giorgi, Mara Massimi, Lapo Bencini, Marco Fidaleo

“…Moreover, scientists are increasingly investigating how the deficiency of vitamins might disrupt specific organ crosstalk, potentially contributing to liver disease. …”
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Frailty and outcomes of vascular access for hemodialysis – a scoping review by Lara R. Dias, Leandro Nóbrega, Tiago Costa-Pereira, Joana Ferreira, Armando Mansilha, Luís Coentrão

“…Frailty assessment might be a valuable tool in shared decision-making regarding vascular access in dialysis population. …”
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Stimulation of Hair Growth Effect by Fermented Ginsenosides Using <i>Levilactobacillus brevis</i> THK-D437 by Eun-Ji Yi, Trang Thi Minh Nguyen, Jeehaeng Jeong, Xiangji Jin, Qiwen Zheng, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

“…Hair growth is crucial for physiological functions and psychological well-being, leading to an increasing demand for research in this area. …”
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GPR56 homozygous nonsense mutation p.R271* associated with phenotypic variability in bilateral frontoparietal polymicrogyria by Tülay Öncü-Öner, Semra Hız-Kurul, Bayram Yüksel, Bekir Ergüner, Aydan Saraç, Handan Güleryüz, Sinem Ağılkaya, İlknur Porsuk-Doru, Aycan Ünalp, Sultan Cingöz

“…Despite the phenotypic similarities in two patients, the potential causes of the variation in the expression of the p.R271* variant between the two affected families might be genetic or epigenetic factors beyond the GPR56 gene. …”
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Exploring the therapeutic potential of different sources of mesenchymal stem cells: a novel approach to combat burn wound infections by Shahrzad Aliniay-Sharafshadehi, Mohammad Hasan Yousefi, Mohammad Hasan Yousefi, Mohammad Ghodratie, Mojtaba Kashfi, Mojtaba Kashfi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Seyed Mehdi Ghoreyshiamiri

“…On the other hand, a burn wound infection creates an environment that is conducive to the growth of bacteria and might put the patient at risk for sepsis. In addition, scarring is unavoidable, and this results in patients having functional and cosmetic issues. …”
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The anticancer thiosemicarbazone triapine exerts immune-enhancing activities via immunogenic cell death induction and FAS upregulation by Bianca Stiller, Alessia Stefanelli, Hemma Schueffl, Marlene Mathuber, Nadiya Skorokhyd, Judith Gufler, Christine Pirker, Martin Holcmann, Rostyslav Panchuk, Maria Sibilia, Doris Marko, Walter Berger, Christian R. Kowol, Sonja Hager, Petra Heffeter

“…Noteworthy, while radiotherapy induces an immune-activating cell death, so called immunogenic cell death (ICD), cisplatin possesses immunomodulatory and ICD-enhancing functions. Interestingly, although there are several indications that suggest that Triapine could also enhance the immune recognition of cancer cells, no investigations in this direction have been reported so far. …”
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