Exploring the Association Between Human Blood Metabolites and Autism Spectrum Disorder Risk: A Bidirectional Mendelian Randomization Study by Wenhua Li, Suya Ma, Yunong Tian

“…Recent studies have suggested that metabolic dysregulation might be linked to the development of ASD; however, causal relationships remain unclear. …”
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Comparative efficacy of cast immobilization versus removable braces in patients with ankle fractures: a systematic review and meta-analysis by Shiran Zhou, Haotian Zheng, Mumin Cao, Zubo Tu, Zhigang Chen, Dong Jiang, Shujun Lv, Haidong Cui

“…Overall, the removable brace is a comfortable ankle fracture option that might improve functional outcomes.…”
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A single-cell RNA sequencing atlas of the healthy canine lung: a foundation for comparative studies by Elodie Rizzoli, Laurence Fievez, Laurence Fievez, Aline Fastrès, Elodie Roels, Thomas Marichal, Thomas Marichal, Thomas Marichal, Cécile Clercx

“…Fibroblasts clusters exhibited a marked transcriptional heterogeneity, some of which might exert immune regulatory functions. Finally, the integration of canine lung cells with an annotated human lung atlas highlighted many similarities in gene expression profiles between species. …”
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Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut by Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin

“…While the intestine is essential for carbohydrate digestion and absorption, the role of PPARγ in enterocyte metabolic functions has been poorly investigated. This study aims at characterizing PPARγ target genes involved in intestinal metabolic functions. …”
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The rubral wing and its connectome by Volker A. Coenen, Alexander Rau, Horst Urbach, Bastian E.A. Sajonz, Marco Reisert

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State and Training Effects of Mindfulness Meditation on Brain Networks Reflect Neuronal Mechanisms of Its Antidepressant Effect by Chuan-Chih Yang, Alfonso Barrós-Loscertales, Daniel Pinazo, Noelia Ventura-Campos, Viola Borchardt, Juan-Carlos Bustamante, Aina Rodríguez-Pujadas, Paola Fuentes-Claramonte, Raúl Balaguer, César Ávila, Martin Walter

“…As expected, significant differences in functional connectivity both between states (rest versus meditation) and between time points (before versus after training) were observed. …”
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Psychological interventions for improvement of symptoms of post-stroke depression – study protocol of the depression-intervention study for optimization of reconvalesence after str... by Lino Braadt, Simone Fischer, Markus Naumann, Philipp Zickler, Thomas Schneider-Axmann, Laura Mühlich, Katharina Körber, Alexander Lassner, Wolfgang Strube, Astrid Röh, Alkomiet Hasan, Michael Ertl

“…Abstract Introduction Besides functional outcomes, mental health and health-related quality of life (HRQoL) are significant measures in chronic diseases, such as stroke. …”
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Electrochemotherapy and Simultaneous Photodynamic Bone Stabilization of Upper Limbs in Metastatic Renal Cancer Disease: Case Report and Literature Review by Ugo Albertini, Andrea Conti, Nicola Ratto, Pietro Pellegrino, Michele Boffano, Raimondo Piana

“…Metastatic bone disease represents a systemic pathology that heavily affects the quality of life of oncologic patients causing pain and functional disability. Methodology. We present the case of a patient with a history of renal cell cancer presenting pathologic fractures of both humeri and proximal right radius. …”
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An efficient strategy to promote food waste composting by adding black soldier fly (Hermetia illucens) larvae during the compost maturation phase by Jiawei Quan, Yumei Wang, Yu Wang, Chunxing Li, Zengwei Yuan

“…Furthermore, BSFL introduction might enhance metabolic functions such as glycolysis, inosine monophosphate biosynthesis, gluconeogenesis, and lysine biosynthesis. …”
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Identification, Expression Profiling, Microbial Binding, and Agglutination Analyses of Two Cathepsin B Genes in Black Rockfish (<i>Sebastes schlegelii</i>) by Xinghua Zhuang, Xingchun Li, Wenpeng Li, Xuan Xu, Fengjun Lin, Yiying Liu, Chonghui Chen, Xiaoxu Zhang, Pei Zhang, Chao Li, Qiang Fu

“…Overall, these findings suggest that the CTSB genes in black rockfish might show essential functions in the host defense of teleosts against bacterial infections, providing valuable insights for further investigations into the immune mechanism of teleost CTSB.…”
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Protein composition and bread volume of German common wheat landraces grown under organic conditions by Nora Jahn, Ulla Konradl, Klaus Fleissner, Sabrina Geisslitz, Katharina A. Scherf

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Bioinformatics Analysis Reveals Diagnostic Markers and Vital Pathways Involved in Acute Coronary Syndrome by Mingshuang Li, Conglin Ren, Chenxia Wu, Xinyao Li, Xinyi Li, Wei Mao

“…Among the predicted miRNAs, hsa-miR-4770, hsa-miR-5195, and hsa-miR-6088 all possessed two target genes, which might be closely related to the development of ACS. …”
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. by Federico Innocenti, Kouros Owzar, Chen Jiang, Amy S Etheridge, Raluca Gordân, Alexander B Sibley, Flora Mulkey, Donna Niedzwiecki, Dylan Glubb, Nicole Neel, Mark S Talamonti, David J Bentrem, Eric Seiser, Jen Jen Yeh, Katherine Van Loon, Howard McLeod, Mark J Ratain, Hedy L Kindler, Alan P Venook, Yusuke Nakamura, Michiaki Kubo, Gloria M Petersen, William R Bamlet, Robert R McWilliams

“…<h4>Conclusion</h4>Our findings propose VDR as a novel determinant of survival in advanced pancreatic cancer patients. Common functional variation in this gene might interact with endogenous vitamin D and gemcitabine treatment to determine improved patient survival. …”
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Neural Activity for Uninvolved Knee Motor Control After ACL Reconstruction Differs from Healthy Controls by Meredith Chaput, Cody R. Criss, James A. Onate, Janet E. Simon, Dustin R. Grooms

“…Clinicians should be aware that the uninvolved limb might also demonstrate whole brain alterations limiting clinical inference from functional symmetry.…”
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Impaired degree centrality and effective connectivity contributed to deficits in cognition and depression in patients with temporal lobe epilepsy by Bailing Qin, Shujun Su, Xuemei Chen, Yuting Sun, Qin Zhou, Huoyou Hu, Lu Qin, Jinou Zheng

“…Cerebral functional activity and neuroimaging features were differentiated between the patient and HC groups based on rsfMRI data, DC, EC, and MVPA. …”
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Corynebacterium glutamicum for Microbial Production of Chitin Oligosaccharides Using Modular Engineering by Chen Deng, Ruijie Xin, Xingjian Li, Liqiang Fan, Yongjun Qiu, Liming Zhao

“…The engineering strategies used in this study might be helpful for the C. glutamicum‐mediated microbial synthesis of functional sugars. …”
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Safety and feasibility of deep brain stimulation of the anterior cingulate and thalamus in chronic refractory neuropathic pain: a pilot and randomized study by Denys Fontaine, Aurélie Leplus, Anne Donnet, Nelly Darmon, Anne Balossier, Bruno Giordana, Benoit Simonet, Petru Isan, Jean Regis, Michel Lanteri-Minet

“…Conclusion This pilot study confirmed the safety of anterior cingulate DBS alone or in combination with thalamic stimulation and suggested that it might improve quality of life of patients with chronic refractory neuropathic pain. …”
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Correlation between the follicular fluid extracellular-vesicle-derived microRNAs and signaling disturbance in the oocytes of women with polycystic ovary syndrome by Zhiqi Liao, Yueping Zhou, Weili Tao, Lin Shen, Kun Qian, Hanwang Zhang

“…We identified 14 potential functional DEmiRNAs in FF-EVs and predicted the target genes of 14 DEmiRNAs using TargetScan. …”
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Construction of a genetic linkage map and QTL mapping of the agronomic traits in Foxtail millet (Setaria italica) by Lulu Gao, Qianxue Zhu, Huan Li, Shiyuan Wang, Jiahui Fan, Tianguo Wang, Lejie Yang, Yuqin Zhao, Yixuan Ma, Lu Chen, Xiaorui Li, Shuqi Dong, Xiaoqian Chu, Xianmin Diao, Xiangyang Yuan, Jiagang Wang, Guanghui Yang

“…The 277 bp insertion/deletion on the promoter of Seita.9G020100 and the one-base (G) insertion/deletion in the third exon of Seita.5G404900 might be candidate functional sites. Furthermore, two markers (Ghd7InDel and GA20oxSTARP-1) were developed based on these two variation sites, respectively. …”
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Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction by Xiaodong Xue, Yu Liu, Jian Zhang, Tao Liu, Zhonglu Yang, Huishan Wang

“…Bcl-xL genetic modification might enhance MSC survival after transplantation. …”
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