Exosomal miR-452-5p Induce M2 Macrophage Polarization to Accelerate Hepatocellular Carcinoma Progression by Targeting TIMP3 by Hu Zongqiang, Chen Jiapeng, Zhao Yingpeng, Yan Chuntao, Wang Yiting, Zhu Jiashun, Li Li

“…Here, we further explored how miR-452-5p functions in HCC. Methods. MiR-452-5p expressions in HCC cells was examined by in situ hybridization. …”
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HLA-DQB1 Allele Polymorphism Associated with Oral Submucous Fibrosis in Hunan, China by Yisi Tan, Yuting Huang, Linkai Guo, Linghang Zhou, Keke Zhu, Yuancong Li, Jin Tan

“…Oral submucous fibrosis (OSF) is a progressive and irreversible disorder of collagen metabolism, resulting in mucosal fibrosis, oral functional changes, and even malignant transformation. …”
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Human Umbilical Cord Mesenchymal Stem Cells Attenuate Severe Burn-Induced Multiple Organ Injury via Potentiating IGF-1 and BCL-2/BAX Pathway by Hongyu Wang, Te Ba, Qiong Wang, Longlong Yang, Chenyi Li, Xingxia Hao, Yue Yin, Lingying Liu

“…Furthermore, these data might provide the theoretical foundation for further clinical applications of hUCMSCs in burn areas.…”
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TGFβ-signaling in Squamous Cell Carcinoma Occurring in Recessive Dystrophic Epidermolysis Bullosa by Julia Knaup, Christina Gruber, Barbara Krammer, Verena Ziegler, Johann Bauer, Thomas Verwanger

“…Moreover, TGFβ signaling might also represent a potentially useful therapeutic target in this disease.…”
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Improving Nitrogen Efficiency: Lessons from Malawi and Michigan by Sieglinde Snapp, Heather Borden, David Rohrbach

“…Interventions that farmers might accept are discussed. The Malawi system uses targeted application of very small amounts of fertilizer (average 18 kg N ha-1) to growing plants. …”
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Therapeutic effects of miR-937-3p by targeting NTN1 expression and regulating apoptosis in an Aβ-induced neuronal cell death by Jiyun Choi, Haewon Jeong, Mahesh Ramalingam, Jinsu Hwang, Seong-Jin Kim, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang

“…Abstract MicroRNAs (miRNAs) have multiple functions that regulate gene expression in various species. …”
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Mapping the evolution of digital human resource management: a systematic review and bibliometric analysis by Md. Nazmus Sakib, Muhammad Shariat Ullah, Md. Mahbubur Rahman

“…However, the study is limited by its selection of keywords that might not capture all relevant DHRM literature, potentially impacting the comprehensiveness and depth of the findings. …”
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Experience of one single surgeon with the first 500 robot-assisted laparoscopic prostatectomy cases in mainland China by Huan Chen, Bijun Lian, Zhenyang Dong, Yan Wang, Min Qu, Feng Zhu, Yinghao Sun, Xu Gao

“…Pelvic lymph node dissection (PLND) might increase the operative time. The total positive surgical margin (PSM) rate was 21.8%. …”
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HEMODYNAMIC AEROBIC MECHANISMS OF EXERCISE TOLERANCE INCREASE IN STABLE ANGINA PATIENTS ON ANTIANGINAL TREATMENT by A. P. Vasiliev, N. N. Streltsova

“…Intensification of oxygen transportation might be followed by the increase of hemodynamic productivity (NF), mostly by activation of extracardiac oxygen consumption factors (PR) and combination of both (ID).…”
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Internalized stigma and mental health disorders among people living with HIV in Akwa Ibom State, Nigeria by Idongesit L. Jackson, Unyime I. Eshiet, Mary R. Akpan, Ubongabasi I. Archibong

“…Abstract Background Assessing internalized stigma and mental health disorders among people living with HIV (PLWH) could identify subgroups that might benefit from targeted interventions. This cross-sectional study sought to evaluate internalized HIV stigma (IHS) and mental health disorders among 405 PLWH attending HIV clinics in Akwa Ibom State, Nigeria. …”
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Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. by Ulrike Esslinger, Sophie Garnier, Agathe Korniat, Carole Proust, Georgios Kararigas, Martina Müller-Nurasyid, Jean-Philippe Empana, Michael P Morley, Claire Perret, Klaus Stark, Alexander G Bick, Sanjay K Prasad, Jennifer Kriebel, Jin Li, Laurence Tiret, Konstantin Strauch, Declan P O'Regan, Kenneth B Marguiles, Jonathan G Seidman, Pierre Boutouyrie, Patrick Lacolley, Xavier Jouven, Christian Hengstenberg, Michel Komajda, Hakon Hakonarson, Richard Isnard, Eloisa Arbustini, Harald Grallert, Stuart A Cook, Christine E Seidman, Vera Regitz-Zagrosek, Thomas P Cappola, Philippe Charron, François Cambien, Eric Villard

“…<h4>Conclusion</h4>We identified eight loci independently associated with sporadic DCM. The functions of the best candidate genes at these loci suggest that proteostasis regulation might play a role in DCM pathophysiology.…”
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Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8. by Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee, Nancy S Longo, Yongping Yang, Jinghe Huang, Robert Parks, Joshua Eudailey, Krissey E Lloyd, S Munir Alam, Barton F Haynes, NISC Comparative Sequencing Program, James C Mullikin, Mark Connors, John R Mascola, Lawrence Shapiro, Peter D Kwong

“…The developmental pathway of 10E8 might therefore serve as a promising template for vaccine design, but samples from time-of-infection-often used to infer the B cell record-are unavailable. …”
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Melanin‐based color variation in response to changing climates in snakes by J. Goldenberg, K. Bisschop, G. Bruni, M. R. Di Nicola, F. Banfi, F. P. Faraone

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Integrated Analyses Identify Immune-Related Signature Associated with Qingyihuaji Formula for Treatment of Pancreatic Ductal Adenocarcinoma Using Network Pharmacology and Weighted... by Xiang Qian, Zhuo Chen, Sha Sha Chen, Lu Ming Liu, Ai Qin Zhang

“…Besides, the putative targets, immune-related targets, and the critical module genes were mapped with the specific disease to select the overlapped genes (OGEs). Functional enrichment analysis of putative targets and OGEs was conducted. …”
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Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough. by Sara Hosseini-Farahabadi, Alireza Baradaran-Heravi, Carla Zimmerman, Kunho Choi, Stephane Flibotte, Michel Roberge

“…Some aminoglycosides that bind to the ribosome decoding center can induce PTC readthrough and restore low levels of full-length functional proteins. However, concomitant inhibition of protein synthesis limits the extent of PTC readthrough that can be achieved by aminoglycosides like G418. …”
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Advanced smart assistance with enhancing social interaction and daily activities for visually impaired individuals using deep learning with modified seagull optimization by Sana Alazwari, Hussah Nasser AlEisa, Mohammed Rizwanullah, Radwa Marzouk

“…The ADD-MSGOEL method is designed to enhance the social life and daily functioning of visually impaired people by accurately detecting damage and potential hazards in their surroundings. …”
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High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration by Songzhe Piao, Lan Zheng, Haihong Zheng, Mengya Zhou, Qin Feng, Suna Zhou, Mang Ke, Haihua Yang, Xuequan Wang

“…Single-sample gene-set enrichment and gene functional enrichment results showed that PDLIM2 was correlated with EMT and immune processes. …”
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Integrating transcriptome and metabolomics revealed the key metabolic pathway response of Amaranthus retroflexus L. to the resistance to fomesafen. by Weifeng Song, Qinghui Wei, Zhenghao Shi, Yaqing Pan, Zhiyong Li, Fangyuan Wang

“…It was found that the resistance mechanism of Amaranthus retroflexus L. might be mainly produced by amino acid metabolic pathway. …”
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The Interplay Between Social Factors and Metabolic Bariatric Surgery Outcomes—A 5‐Year Prospective Study by Uta Sailer, Fatemeh Asgari, Jon A. Kristinsson, Ingela Lundin Kvalem

“…In the context of metabolic bariatric surgery (MBS), these relationships might influence emotion regulation and health behaviors that affect surgical outcomes. …”
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Cuproptosis-related gene ACAD8 inhibits the metastatic ability of colorectal cancer by inducing cuproptosis by HuiE Zhuang, Yizhen Chen, Yizhen Chen, Sifu Huang

“…Pathway enrichment analysis suggested that ACAD8 might inhibit the metastasis of CRC by regulating pathways such as response to metal ions and tight junction organization. …”
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