A novel plasma circular RNA circFARSA is a potential biomarker for non‐small cell lung cancer by Dong Hang, Jing Zhou, Na Qin, Wen Zhou, Hongxia Ma, Guangfu Jin, Zhibin Hu, Juncheng Dai, Hongbing Shen

“…Bioinformatics and functional analyses were performed to reveal biological effects of circRNAs on lung cancer cells. …”
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Modeling and Monitoring Terrestrial Primary Production in a Changing Global Environment: Toward a Multiscale Synthesis of Observation and Simulation by Shufen Pan, Hanqin Tian, Shree R. S. Dangal, Zhiyun Ouyang, Bo Tao, Wei Ren, Chaoqun Lu, Steven Running

“…We also discuss how terrestrial primary production might respond to climate change and increasing atmospheric CO2 and uncertainties associated with model and data. …”
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Vitamin C Protected Human Retinal Pigmented Epithelium from Oxidant Injury Depending on Regulating SIRT1 by Wei Wei, Langen Li, Yufeng Zhang, Geriletu, Jia Yang, Yanmei Zhang, Yiqiao Xing

“…It suggested that combined application of Vit C and RSV might be a promising therapeutic method for AMD.…”
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Extracellular matrix protein anosmin-1 regulates Schwann cell-astrocyte interaction for regenerative axon targeting in dorsal root crush injury model by Xichen Xuan, Xuechun Chu, Ruiliang Wang, Lu Liu, Daqing Li, Pierre Marc Bouloux, Ying Li, Youli Hu

“…These results suggest that anosmin-1 can regulate SC/AS interactions at the peripheral/central boundary site to open the glial barrier for regenerating axons crossing, targeting, and establishing functional neuronal circuits. Anosmin-1 might have a potential application in repair of spinal cord injuries, particularly in combination with SCs for autologous cell transplantation.…”
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Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake by Sophie A. Montandon, Pierre Beaudier, Asier Ullate-Agote, Pierre-Yves Helleboid, Maya Kummrow, Sergi Roig-Puiggros, Denis Jabaudon, Leif Andersson, Michel C. Milinkovitch, Athanasia C. Tzika

“…Conclusions Our genomic, transcriptomic, and functional analyses identify a plasma membrane anion channel to be involved in color pattern development in snakes and show that an active LTR-retrotransposon might be a key driver of trait diversification in corn snakes.…”
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Injectable hydrogels for Fenton-like Mn2+/Fe2+ delivery with enhanced chemodynamic therapy prevent osteosarcoma recurrence and promote wound healing after excision surgery by Lutong Wang, Haoyu Guo, Weiyue Zhang, Xingyin Li, Ziliang Su, Xin Huang

“…By simple local injection, the hydrogel could form a protective barrier on the surgical wound after osteosarcoma excision, which could promote wound healing and steady release of MnO2/Fc nanoparticles. The released MnO2/Fc might undergo the Fenton reaction through Mn2+/Fe2+ to inhibit osteosarcoma cells with chemodynamic therapy (CDT). …”
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Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells by Susann A. Dorosz, Aurélien Ginolhac, Thilo Kähne, Michael Naumann, Thomas Sauter, Alexandre Salsmann, Jean-Luc Bueb

“…Our findings provide new evidence about the IL27-dependent proinflammatory signaling which may be under the control of calprotectin and highlight the need for further investigations on molecules which might have antiatherosclerotic functions.…”
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CO-EXPRESSION OF MEMBRANE-BOUND TUMOR NECROSIS FACTOR-α RECEPTORS IN MAJOR SUBPOPULATIONS OF IMMUNOCOMPETENT CELLS IN HEALTHY INDIVIDUALS AND PATIENTS WITH RHEUMATOID ARTHRITIS AS... by Yu. V. Zhukova, A. A. Alshevskaya, F. D. Kireev, O. A. Chumasova, N. S. Shkaruba, A. E. Sizikov, Yu. A. Lopatnikova, D. V. Demina, A. V. Karaulov, A. N. Silkov, S. V. Sennikov

“…A pleiotropic cytokine TNFα is an important inflammatory mediator of a number of diseases; its biological functions are fulfilled through two different receptors, TNFR1 and TNFR2. …”
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ZIP13 marks muscle satellite cells and contributes to their quiescent and active phase balance by Emi Yoshigai, Takafumi Hara, Masaki Hashimoto, Hidenao Tsuzuki, Takaya Abe, Kenichi Inoue, Ayaka Noguchi, Takuto Ohashi, Toshiyuki Fukada

“…Altogether, our results illustrate that ZIP13 might be positively involved in skeletal muscle regeneration by controlling the quiescent/activated phase balance of MuSCs through autoregulatory ZIP13 expression, and that newly generated Zip13-GFP KI mice would be useful for investigating the roles and dynamics of ZIP13-expressing cells.…”
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VHL missense mutation delineate aggressive clear cell renal cell carcinoma subtype with favorable immunotherapeutic response by Li Liu, Jiejie Xu, Jianming Guo, Wenbin Jiang, Ziyang Xu, Youqi Qiu, Boyu Zhang, Jiangting Cheng, Jiyan Luo

“…VHLMiss ccRCC exhibited hyper-activated cell cycle and nuclear factor kappa B (NF-κB) instead of canonical hypoxia inducible factor pathways, which might contribute to its proliferative morphology. …”
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Key Proteins in Rat Cerebral Cortex: Application of <i>Cornu aspersum</i> Extract as a Neuroprotective Agent in Alzheimer’s Type Dementia by Ventseslav Atanasov, Lyudmila Velkova, Lyubka Tancheva, Aleksandar Dolashki, Reni Kalfin, Pavlina Dolashka

“…Brain cortex was separated and the expressions of various proteins related to memory and cognitive functions were identified. We found that the expression of Ubiquitin carboxyl-terminal hydrolase isozyme L1, Calbindin, Vacuolar ATP synthase catalytic subunit A, Tropomyosin beta chain, 14-3-3 zeta/delta, Kinesin-1 heavy chain, and Stathmin-4 significantly differs in SE-protected rats as compared to dement animals treated only by Sco, and these brain proteins might be potential therapeutic targets for Alzheimer’s-type dementia treatment.…”
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MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2 by Yali Yin, Shubin Hong, Shuang Yu, Yanrui Huang, Shuwei Chen, Yujie Liu, Quan Zhang, Yanbing Li, Haipeng Xiao

“…Our study aimed to explore the biological functions and the underlying molecular mechanisms of miR-195 in PTC. …”
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Genome-Wide Identification and Characterization of Heat Shock Proteins in the Stored-Product Pest <i>Rhyzopertha dominica</i> (Fabricius): Phylogenetic, Structural, and Stress-Indu... by Yueliang Bai, Yanzhu Xie, Junji Yao, Fangfang Zeng, Dianxuan Wang

“…Our study provides a theoretical basis for further research on HSP functions in <i>R. dominica</i>.…”
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Study of Expression of <i>MST3</i> in Myeloid Leukaemia by Boro Arthi, Krishnaswamy Sujatha, Sridhar Gopal, Balasubramanian Balamuralikrishnan, Meyyazhagan Arun, Pappuswamy Manikantan, Palanisamy Sampathkumar, Arumugam Vijaya Anand

“…<i>MST3</i> is a gene of the GCK family that has a role in apoptosis, along with other cellular functions like cellular differentiation, cell cycle, metabolism, and others. …”
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Connectivity Analysis during Rubber Hand Illusion—A Pilot TMS-EEG Study in a Patient with SCI by Vanessa N. Frey, Aljoscha Thomschewski, Patrick B. Langthaler, Alexander B. Kunz, Yvonne Höller, Eugen Trinka, Raffaele Nardone

“…This connectivity pattern might represent a neuroplastic response in the attempt to overcome the functional impairment of the patient resulting in a similar overall connectivity pattern to the healthy participants, yet with a higher sensitivity towards RHI and a higher laterality. …”
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Effectiveness and safety of acupuncture for carpal tunnel syndrome: An overview of systematic reviews and meta-analyses by Yulin Liu, Chao Wang, Qi Wang, Qing Zhang, Songhao Ning, Quanai Zhang

“…Conclusions: Acupuncture might be beneficial for CTS. However, given the existing evidence limitations, the efficacy of acupuncture for CTS requires confirmation through further high-quality research. …”
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MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells by Chao Sun, Lai-gang Huang, Bing Leng, Yanting Guo, Chen Chen, Ruijie Lv, Yan Dong, Tian-tian Gao, De-qing Sun

“…We concluded that miR-32-5p negatively regulated the DSC2 expression, might be a potential therapeutic targeting of cancers, most especially in GC.…”
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Lipid Levels and Atherogenic Indices as Important Predictive Parameters in the Assessment of Cardiovascular Risk in Patients with Pulmonary Tuberculosis—Slovak Pilot Study by Karolína Kubalová, Igor Porvazník, Mária Majherová, Lenka Demková, Anna Piotrowska, Marta Mydlárová Blaščáková

“…Cardiovascular diseases significantly worsen the functional and vital prognosis of tuberculosis patients. …”
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Health-related quality of life of toddlers during and after cancer treatment by Elin Irestorm, Raphaele R.L. van Litsenburg, Heleen Maurice-Stam, Kelly L.A. van Bindsbergen, Annelies M.C. Mavinkurve-Groothuis, Marita Partanen, Martha Grootenhuis

“…Treatment with immunotherapy is likely to be a marker of disease severity and might represent other underlying factors affecting HRQOL. …”
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Optimizing imputation strategies for mass spectrometry-based proteomics considering intensity and missing value rates by Yuming Shi, Huan Zhong, Jason C. Rogalski, Leonard J. Foster

“…Missing values (MVs) in omic datasets affect the power, accuracy, and consistency of statistical and functional analyses. In mass spectrometry (MS)-based proteomics, MVs can arise due to several reasons: peptides could be below instrumental detection limits, peptides or proteins might be absent or depleted from the sample for biological or technical reasons, or data processing could fail to detect a real signal. …”
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