Single cell RNA sequencing to identify an Immunogenic cell death related prognostic signature in intrahepatic cholangiocarcinoma by Bowen Sha, Fei Tong, Qinghua Shu, Miao Wu, Liang Zhao, Yufeng Zhang

“…Distinct biological functions and metabolic characteristics were observed in iCCA between high- and low-ICD groups. …”
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Predictors of Fall-Related Injuries in Fallers—A Study in Persons with Cognitive Impairment by Per G. Farup, Knut Hestad, Knut Engedal

“…Falls were independent of the disorders causing the impaired functions. Because most falls are innocent, knowledge of predictors of fall-related injuries seems more clinically relevant than the predictors of falls. …”
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Local arrangement of microfibrillar-associated protein 5 with neurovascular and extracellular components in non- and ischemia-affected brain regions of mice by Corinna Höfling, Corinna Höfling, Steffen Roßner, Bianca Flachmeyer, Wolfgang Härtig, Dominik Michalski

“…Stroke often leads to death or functional impairment, and neuroprotective strategies are still lacking. …”
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A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation. by Eoin N Leen, Frédéric Sorgeloos, Samantha Correia, Yasmin Chaudhry, Fabien Cannac, Chiara Pastore, Yingqi Xu, Stephen C Graham, Stephen J Matthews, Ian G Goodfellow, Stephen Curry

“…These observations define important structural details of a functional interaction between norovirus VPg and eIF4G and reveal a binding interface that might be exploited as a target for antiviral therapy.…”
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Streamlining cVEP Paradigms: Effects of a Minimized Electrode Montage on Brain–Computer Interface Performance by Milán András Fodor, Atilla Cantürk, Gernot Heisenberg, Ivan Volosyak

“…Three experimental conditions were tested: a baseline 16-electrode configuration, a reduced 6-electrode setup without retraining, and a reduced 6-electrode setup with retraining. (3) Results: Our results indicate that, on average, performance declines with fewer electrodes; nonetheless, retraining restored near-baseline mean Information Transfer Rate (ITR) and accuracy for those participants for whom the system remained functional. The results reveal that for a substantial number of participants, the classification pipeline fails after electrode removal, highlighting individual differences in the cVEP response characteristics or inherent limitations of the classification approach. (4) Conclusions: Ultimately, this suggests that minimal cVEP-BCI electrode setups capable of reliably functioning across all users might only be feasible through other, more flexible classification methods that can account for individual differences. …”
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The COVID‐19 Pandemic and Its Influence on Patients With Myotonic Dystrophy Type 1: Lessons Learned by Vera E. A. Kleinveld, Johanna E. Bruijnes, Samuel Labrecque, Danielle E. G. Jeurissen‐Bekkering, Catharina G. Faber, Corinne G. C. Horlings

“…ABSTRACT Introduction: Myotonic dystrophy type 1 (DM1) patients might represent a high‐risk population for severe COVID‐19 disease, as cardiopulmonary symptoms are part of the clinical spectrum of DM1. …”
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Efficacy and safety of Fe-curcumin coordination polymer nanodots to prevent corneal neovascularization in alkali burn models by Yan Huo, Lele Song, Zhihui Han, Yihan Yang, Tianyao Wang, Zhao Chen, Qi Yang, Yongkang Qiu, Wenpeng Huang, Ran Tao, Liang Cheng, Lei Kang

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Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni. by Enyara R Morais, Katia C Oliveira, Renato G de Paula, Alice M M Ornelas, Érika B C Moreira, Fernanda Rafacho Badoco, Lizandra G Magalhães, Sergio Verjovski-Almeida, Vanderlei Rodrigues

“…Here, we used expression microarrays to measure the genome-wide changes in gene expression of S. mansoni adult worms exposed in vitro to MG-132, followed by in silico functional analyses of the affected genes using Ingenuity Pathway Analysis (IPA). …”
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Temperature-driven metabolic shifts in duck egg components during early embryogenesis: from diapause to active developmental phase by Zekuan Zuo, Qian Chen, Chengxin Hu, Qian Tang, Chenling Song, Hehe Liu

“…Differential metabolite analysis in yolk and albumen was integrated with KEGG pathway enrichment to identify functional shifts linked to embryonic reactivation. …”
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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. by Sreeram V Ramagopalan, Narelle J Maugeri, Lahiru Handunnetthi, Matthew R Lincoln, Sarah-Michelle Orton, David A Dyment, Gabriele C Deluca, Blanca M Herrera, Michael J Chao, A Dessa Sadovnick, George C Ebers, Julian C Knight

“…We hypothesised that this environmental candidate might interact with inherited factors and sought responsive regulatory elements in the MHC class II region. …”
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Characterization of the transcriptional cellular response in midgut tissue of temephos-resistant Aedes aegypti larvae by Elisama Helvecio, Antonio Mauro Rezende, Maria J. R. Bezerra, Osvaldo Pompílio de-Melo-Neto, Maria Alice Varjal de Melo Santos, Tatiany Patrícia Romão, Constância Flávia Junqueira Ayres

“…Our results indicate that metabolic resistance might involve a larger and more significant number of detoxification enzymes, with different functional roles, than previously shown with other mechanisms, also contributing to the resistance phenotype in the Ae. aegypti RecR colony. …”
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Current state of the art of traditional and minimal invasive epilepsy surgery approaches by Fabian Winter, Marie T. Krueger, Daniel Delev, Tom Theys, Dirk MP Van Roost, Kostas Fountas, Olaf E.M.G. Schijns, Karl Roessler

“…Discussion and conclusion: Understanding the benefits and disadvantages of different surgical approaches and strategies in traditional and minimal invasive epilepsy surgery might improve the surgical decision tree, as not all procedures are appropriate for all patients.…”
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Understanding climate change anxiety and anticipatory climate disaster stress: A survey of residents in a high-risk California county during wildfire season by E Alison Holman, Tiffany Junchen Tao, Kayley D Estes, Farshid Vahedifard, Roxane Cohen Silver

“…These responses could be temporally appropriate and functionally adaptive, given the immediacy of a potential fire.Clinical implications Climate change anxiety and anticipatory climate disaster stress should not be oversimplified as typical clinical symptoms because their presence might motivate adaptive self-protective behaviours in the face of an upcoming disaster.…”
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Quercetin-Fortified Animal Forage from Onion Waste: A Zero-Waste Approach to Bioactive Feed Development by Janusz Wojtczak, Krystyna Szymandera-Buszka, Joanna Kobus-Cisowska, Kinga Stuper-Szablewska, Jarosław Jakubowicz, Grzegorz Fiutak, Joanna Zeyland, Maciej Jarzębski

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Lingvocultural Specifics of the Communicative Behaviour in Arabic English-language Business Discourse by L. A. Kochetova, Yassien Sh. S. Al-Bayati

“…In the BLC the situations when commissive speech acts correlate with apology the addresser commits themselves to obligation not to perform actions that are undesirable for the addressee or prevent the circumstances that might have negative consequences for the addressee. …”
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Feasibility of an exergaming training program in type 2 diabetes mellitus: A mixed method study by Nikola Savic, Heidi Petry, Eling D. de Bruin, Roger Lehmann, Patrick Eggenberger, Manuela Adcock, Ruth Hirschmann, Ruud H. Knols

“…Secondarily, possible effects on physical, functional, and patient-reported outcomes were explored. …”
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System theory as a tool for searching for new scientific directions and problematic aspects of pharmacy in the context of social responsibility by N. O. Tkachenko, O. A. Ryzhov, B. Р. Hromovyk

“…The system approach and system analysis allow developing methods for solving problems that arise within the system, taking into account the aims and functions of the system under consideration, its structure, and all external and internal connections. …”
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Environmental drivers of the resistome across the Baltic Sea by Joeselle M. Serrana, Francisco J. A. Nascimento, Benoît Dessirier, Elias Broman, Malte Posselt

“…Furthermore, our analysis suggests that microbial community composition and mobile genetic elements might be crucial in shaping ARG diversity and composition. …”
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Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics by Benjiao Gong, Yanlei Kao, Chenglin Zhang, Fudong Sun, Zhaohua Gong, Jian Chen

“…The DEGs mainly regulated biological processes covering response to stimulus, metabolic process, and affected molecular functions containing protein binding and catalytic activity. …”
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Unravelling the nexus of stroke and dementia: Deciphering the role of secondary neurodegeneration in orchestrating cognitive decline by Shannon M. Stuckey, Rebecca J. Hood, Lin Kooi Ong, Isabella M. Bilecki, Lyndsey E. Collins‐Praino, Renée J. Turner

“…A combination of greater life expectancy, an increase in the number of strokes in young individuals, and improved survival have inherently increased the number of years patients are living post‐stroke, highlighting the critical need to understand the long‐term effects of stroke, including how pathological changes in the brain might give rise to functional and behavioral changes in stroke survivors. …”
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