Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria. by Ousman Jobe, Gina Donofrio, Guangping Sun, Dmitry Liepinsh, Robert Schwenk, Urszula Krzych

“…The in vitro induction of functional CD8+ T(EM) cells by cCD8alpha+ DC was inhibited by anti-MHC class I and anti-IL-12 mAbs. …”
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Multimodal Communication in Virtual and Face-to-Face Settings: Gesture Production and Speech Disfluency by Burcu Arslan, Can Avcı, Demet Özer

“…These f indings signal an interplay between the cognitive functions of different disfluency types and communicative strategies. …”
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Sonographic assessment of hand and wrist tendons abnormalities by Asmaa Hussein Habib, Hatem Mohamed El-Azizi, Salma Hesham Hefny, Omar Mohammed Nouh

“…Abstract Background Tendons of the hand and wrist are the seat of different types of pathologies that might be attributed to degenerative changes, inflammation, or even rupture. …”
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Examining the relationship between income and both mental and physical health among adults in the UK: Analysis of 12 waves (2009-2022) of Understanding Society. by Howard Robert Reed, Daniel Nettle, Fiorella Parra-Mujica, Graham Stark, Richard Wilkinson, Matthew Thomas Johnson, Elliott Aidan Johnson

“…These findings facilitate microsimulation modelling including an estimation of the impact of changes in QALYs, from changes in income, enabling a more detailed and complete understanding of which socioeconomic interventions might begin to address some of the causes of long-term health conditions that are underpinned by socioeconomic determinants.…”
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Aging safely in Alentejo – understanding for action - preventing falls and violence against older people: study rationale, aims, design, and preliminary results by Catarina Pereira, Jorge Bravo, Gorete Reis, Felismina Mendes

“…Abstract Background Falls and violence against older people might represent a joint public health problem, as both may result in injury, fear, social isolation, sedentary behavior and dependence or even death. …”
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Rapid activation of Rac GTPase in living cells by force is independent of Src. by Yeh-Chuin Poh, Sungsoo Na, Farhan Chowdhury, Mingxing Ouyang, Yingxiao Wang, Ning Wang

“…It is well known that mechanical forces are crucial in regulating functions of every tissue and organ in a human body. …”
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Sensory Attenuation and Agency in Cooperative and Individual Contexts: Exploring the Role of Empathy in Action Perception by Sofia Tagini, Ada Ghiggia, Sara Falco, Lorys Castelli, Alessandro Mauro, Federica Scarpina

“…To control for the factor of gender that might potentially influence prosocial attitudes, only cisgender women were included in this study. …”
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Different Stability and Proteasome-Mediated Degradation Rate of SMN Protein Isoforms. by Denise Locatelli, Mineko Terao, Mami Kurosaki, Maria Clara Zanellati, Daniela Rita Pletto, Adele Finardi, Francesca Colciaghi, Enrico Garattini, Giorgio Stefano Battaglia

“…However, to what extent the impairment of these two SMN functions contributes to SMA pathogenesis remains unknown. …”
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The effects of integrated traditional Chinese and western medicine rehabilitation programs on post-acute ankle sprain: A randomized controlled trial study protocol. by Hang Gao, Xiao Chen, Jiayi Ren, Xinglai Zhang, Yuqian Hu, Zhao Ma, Yuanjia Gu, Jiming Tao, Weian Yuan

“…The current clinical guidelines for post-acute ankle sprains are still controversial. Pain and functional impairment are the most significant symptoms after ankle sprain. …”
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Single-cell sequencing systematically analyzed the mechanism of Emdogain on the restoration of delayed replantation periodontal membrane by Yanyi Liu, Yuhao Peng, Lanhui Chen, Yangfan Xiang, Ximu Zhang, Jinlin Song

“…Gene modules associated with angiogenesis, osteogenesis, and odontoblast differentiation were identified, suggesting EMD might facilitate osteogenesis and odontoblast differentiation by upregulating endothelium-related genes. …”
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Dietary supplement of Acanthopanax senticosus decoction formula improves immune response via intestine flora of rabbits by Jing Nie, Qin Liu, Shihui Huang, Jiafu Wang, Xi Niu, Xueqin Ran

“…Young rabbits are sensitive to surrounding changes and conditioned pathogens in intestine which might result in slow inflammation and diarrhea after microbial invasion. …”
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Influence of asparagus straw returns associated with vegetable species on microbial diversity in the rhizosphere by Yuling Yin, Yuan Liu, Shaochun Luo, Jinsong Zhou

“…Special beneficial functional microbes, such as some Paenibacillus and Cephaliophora_tropica for cucumbers and Lysinibacillus and Ramlibacter for eggplants, are affected by certain vegetables. …”
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Feasibility of a goal sharing digital platform designed to empower children with disability and their families: A qualitative, pre-implementation study by Meghan Wilson, Bridget O’Connor, Marnie Drake, Adam Scheinberg, Christine Imms, Rose Babic, Danny Hui, George Charalambous, Sarah Knight

“…Views on using a digital platform were captured by sub-categories: potential to empower families ; collaboration and shared understanding; communication in your own time ; everything in the same place ; accessible and user friendly ; functionality and preferred features ; workload; some families might not engage with it and using new technology . …”
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The surface tension and cloud condensation nuclei (CCN) activation of sea spray aerosol particles by J. Kleinheins, N. Shardt, U. Lohmann, C. Marcolli

“…Since common climate models use parameterizations that are based on classical Köhler theory, these results suggest that the CCN activity of small SSA particles might be underestimated in climate models.</p>…”
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Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. by Leonie Unterholzner, Rebecca P Sumner, Marcin Baran, Hongwei Ren, Daniel S Mansur, Nollaig M Bourke, Felix Randow, Geoffrey L Smith, Andrew G Bowie

“…Thus C6 contributes to VACV virulence and might do so via the inhibition of PRR-induced activation of IRF3 and IRF7.…”
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Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain. by Helen M Wise, Edward C Hutchinson, Brett W Jagger, Amanda D Stuart, Zi H Kang, Nicole Robb, Louis M Schwartzman, John C Kash, Ervin Fodor, Andrew E Firth, Julia R Gog, Jeffery K Taubenberger, Paul Digard

“…To better understand how IAV might replicate without M2, we studied the reversion mechanism of an M2-null virus. …”
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Promoting Social Participation in the Primary Care Field: An Ecological Study on the Potential Reduction of Multimorbidity Prevalence by Ryota Takahashi, Tadao Okada, Kazushige Ide, Taishi Tsuji, Katsunori Kondo

“…Methods: Study design was a cross sectional study, which used the data from the Japan Gerontological Evaluation Study, a population-based gerontological study among functionally independent older adults aged ≥65 years in Japan. …”
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Mapping Hsp104 interactions using cross‐linking mass spectrometry by Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak

“…Recent cryo‐EM structures of AAA+ molecular machines have uncovered nuanced changes in their conformation that underlie their specialized functions. Structural knowledge of these molecular machines in complex with substrates begins to explain their mechanism of activity. …”
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An integrated proteo-transcriptomics approach reveals novel drug targets against multidrug resistant Escherichia coli by Manisha Aswal, Nirpendra Singh, Neelja Singhal, Manish Kumar

“…Bioinformatic analysis using GO-terms, COG and KEGG functional annotations revealed that the concordantly overexpressed genes of MDR E. coli were involved primarily in biosynthesis of secondary metabolites, aminoacyl-tRNAs and ribosomes. …”
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Distinct phenotype, longitudinal changes of numbers and cell-associated virus in blood dendritic cells in SIV-infected CD8-lymphocyte depleted macaques. by Caroline Soulas, Patrick J Autissier, Tricia H Burdo, Michael Piatak, Jeffrey D Lifson, Kenneth C Williams

“…However, changes of myeloid DCs (mDCs) are ambiguous since they are studied as a homogeneous CD11c+ population despite phenotypic and functional heterogeneity. Heterogeneity of CD11c+ mDCs in primates is poorly described in HIV and SIV infection. …”
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