Anti-oxidant, anti-apoptotic and anti-inflammatory effects of geraniin in spinal cord injury in rats: role of COX-2 by Yaping Wang, XinXu Chu, Guangcui Hu, Jianbo Chang

“…RESULTS: We found that therapy with GER could enhance functional recovery in a dosage-dependent manner, as well as reduce the occurrence of apoptosis, and mitigate the inflammatory and oxidative response in rats with SCI. …”
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Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. by Hana Koutnikova, Markku Laakso, Lu Lu, Roy Combe, Jussi Paananen, Teemu Kuulasmaa, Johanna Kuusisto, Hans-Ulrich Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markolf Hanefeld, Robert W Williams, Johan Auwerx

“…To identify new genes responsible for hypertension, genetic analysis of recombinant inbred strains of mice followed by human association studies might prove powerful and was exploited in our current study. …”
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Site-2 protease Sll0528 interacts with RbcR to regulate carbon/nitrogen homeostasis in the cyanobacterium Synechocystis sp. PCC 6803 by Shiqi Lin, Taotao Zheng, Yongyi Mo, Ge Zhang, Gu Chen

“…Further analysis suggests that this downregulation might result from improper post-transcriptional regulation of RbcR, which depends on its interaction with Sll0528. …”
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Lack of Genotype and Phenotype Correlation in a Rice T-DNA Tagged Line Is Likely Caused by Introgression in the Seed Source. by Fu-Jin Wei, Yuan-Ching Tsai, Yu-Ming Hsu, Yu-An Chen, Ching-Ting Huang, Hshin-Ping Wu, Lin-Tzu Huang, Ming-Hsin Lai, Lin-Yun Kuang, Shuen-Fang Lo, Su-May Yu, Yann-Rong Lin, Yue-Ie Caroline Hsing

“…Several rice insertional mutant libraries are publicly available for systematic analysis of gene functions. However, the tagging efficiency of these mutant resources-the relationship between genotype and phenotype-is very low. …”
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Motor planning in chronic upper-limb hemiparesis: evidence from movement-related potentials. by Philip John Ainsley Dean, Ellen Seiss, Annette Sterr

“…Neurophysiological studies have focused on motor execution deficits in relatively high functioning patients. Much less is known about the influence exerted by processes related to motor preparation, particularly in patients with poor motor recovery.…”
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Empagliflozin Plays Vasoprotective Role in Spontaneously Hypertensive Rats via Activation of the SIRT1/AMPK Pathway by Monika Kloza, Anna Krzyżewska, Hanna Kozłowska, Sandra Budziak, Marta Baranowska-Kuczko

“…SHR showed increased SGLT2 and SIRT1 expression and decreased pAMPK/AMPK levels in sMAs. In conclusion, EMPA might exert vasoprotective effects in hypertension by enhancing endothelium-dependent relaxation and reducing constriction via AMPK/SIRT1 pathways. …”
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Procedure and Clinical Success of Drug-Coated Balloon Fistuloplasty of the Drainage Vein in Dysfunctional Native Arteriovenous Fistulas by Zeki Temiztürk, Davut Azboy, Fevzi Sarper Türker

“…Haemodialysis through native AVFs with restored functionality contributes positively to the life span and the quality of life of the patient. …”
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Sleep Quality as a Mediator of Internet Gaming Disorder and Executive Dysfunction in Adolescents: Cross-Sectional Questionnaire Study by Michoel L Moshel, Wayne Warburton, Rainer Thomasius, Kerstin Paschke

“… Abstract BackgroundInternet gaming disorder (IGD) has been associated with impairments in executive functioning, particularly inattention and impulsivity. …”
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Age and chest computed tomography severity score are predictors of long-COVID by Merve Erkan

“…Clinical factors such as age and intensity (moderate or acute) of COVID-19 have been found to be associated with long-COVID. Many tissues might be damaged functionally or structurally during acute COVID-19 which can be detected by blood assays and chest computed tomography (CT). …”
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HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome. by John M O'Dowd, Anamaria G Zavala, Celeste J Brown, Toshio Mori, Elizabeth A Fortunato

“…Our data confirm that NER functions in HCMV-infected cells and almost exclusively repairs the viral genome to the detriment of the host's genome.…”
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Exploring the job resources experienced by employees with hearing impairment in South Africa by Strauss Chelius, Bouwer E. Jonker, Marissa Brouwers

“…Research purpose: This study aimed to explore the aspects that EwHIs might regard as job resources within the South African context. …”
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Developmental differences in social information use under uncertainty: A neurocomputational approach by Lieke Hofmans, Wouter van den Bos

“…We discuss how these observations might be explained by ongoing neural development during adolescence, leading to reduced metacognitive abilities which hinder the effective integration of precision signals. …”
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Discussing Relations Between Dynamic Business Environments and Big Data Analytics by Daniel Staegemann, Matthias Volk, Christian Daase, Klaus Turowski

“…However, as of today, the developed solutions are oftentimes perceived as completed products, without considering that the application in highly dynamic environments might benefit from a deviation of this approach. …”
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Pine needles attenuate receptor activator for nuclear factor-B ligand (RANKL)-induced trabecular bone loss by inhibiting osteoclast differentiation by Ki-Shuk Shim, Jin Yeul Ma

“…Conclusion: WEPN inhibition on osteoclastogenesis could contribute to attenuate RANKL-induced trabecular bone loss in vivo. Therefore, it might suggest that WEPN could be prescribed in traditional medicine or used in health functional food to prevent or treat osteoporotic bone diseases. …”
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Problems and Prospects of Regulating Relations within a Deal Effected with Participation of Artificial Intelligence by D. A. Kazantsev

“…To solve the issue of responsibility for the decisions resulting from the implementation of algorithms of a software and hardware package, we propose several models of distributing such responsibility among its creator, owner, and other persons, whose actions might influence the results of such an algorithm functioning. …”
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Trend Analysis of Annual and Monthly Rainfall in Erbil City, Kurdistan Region, Iraq by Saud A. Hussien, Basil Y. Mustafa, Farzand K. A. Medhat

“…Furthermore, the results obtained in this work are promising and might help hydraulic civil and water resource engineers in the design of hydraulic structures…”
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Tear deficiency transforms spatial distribution of corneal calcitonin gene-related peptide-positive nerves in rats by Takeshi Kiyoi, Akihiro Nakajima, Qiang He, Li Liu, Shijie Zheng, Shizuka Kobayashi, Junsuke Uwada, Takayoshi Masuoka

“…In dry eye disease (DED), corneal nerves undergo functional and morphological changes that may be involved in abnormal ocular surface sensation and corneal pathology. …”
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Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer’s Disease: A Metabolomic and Proteomic Approach by Huiling Wei, Tianyi Du, Weiwei Zhang, Wei Ma, Yao Yao, Juan Li

“…Behavioral tests demonstrated that TSS effectively improved the learning and memory functions of mice. <b>Conclusions</b>: Our findings suggest that TSS ameliorate cognitive decline through regulating neuroinflammatory pathways, cAMP and cGMP signaling, and synaptic plasticity pathways, providing insights into its therapeutic potential in AD.…”
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Survival Rates of Microbial Communities from Livestock Waste to Soils: A Comparison between Compost and Digestate by Maiko Akari, Yoshitaka Uchida

“…Further investigation is needed to fully understand their impact on soils’ microbial functions.…”
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Fluorometric combination analysis of conformational changes in urea-induced unfolding of soybean protein isolates and their complexes with casein. by Yangchao Gao, Yuchuan Li, Yifan Yang, Hongying He, Yanqiong Li, Shuhui Yu, Haiying Wang, Yuyu Zhang, He Liu

“…Soybean proteins isolates (SPIs) could misfold to form amorphous aggregates after unfolding due to processing conditions, leading to a decrease in their solubility, and casein might be able to block the formation of amorphous aggregates. …”
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