Identification and immune function of the teleost-specific chemokine CCL39 in black rockfish (Sebastes schlegelii) by Fengjun Lin, Pei Zhang, Xuan Xu, Chonghui Chen, Xiaoxu Zhang, Yiying Liu, Chao Li, Qiang Fu

“…In this study, we systematically characterized CCL39, a teleost-specific chemokine, in black rockfish, Sebastes schlegelii (SsCCL39), explored its expression patterns following Aeromonas salmonicida infection, and revealed their immune function and antibacterial mechanism. Firstly, SsCCL39 contained a 309 bp ORF encoding 102 amino acids. …”
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Damage to white matter networks resulting from small vessel disease and the effects on cognitive function by Natalie Busby, Janina Wilmskoetter, Roger Newman-Norlund, Sarah Newman-Norlund, Sara Sayers, Sarah C. Wilson, Nicholas Riccardi, Alex Teghipco, Rebecca W. Roth, Lumi Bakos, Chris Rorden, Julius Fridriksson, Leonardo Bonilha

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Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

“…Cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, PSA, thyroid-stimulating hormone, and T4 levels did not show significant differences but might warrant further exploration. Conclusion: This study demonstrates an association between poor glycemic control and impaired erectile function in diabetic men. …”
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Immune cells and the trajectories of depression, anxiety, and cognitive function among people with amyotrophic lateral sclerosis by Yihan Hu, Elie Deeba, Ulf Kläppe, Linn Öijerstedt, John Andersson, Nicolas Ruffin, Fredrik Piehl, Caroline Ingre, Fang Fang, Christina Seitz

“…Certain T cell subsets measured at diagnosis might be indicative of depression trajectories post-diagnosis.…”
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Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives by Tinne Vandenbroeke, Ellen Andries, Marc J.W. Lammers, Anouk Hofkens-Van den Brandt, Griet Mertens, Vincent Van Rompaey

“…Evoked response potentials might have potential as an objective marker for cognition in this study population. …”
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Long-term tuina can inhibit the occurrence of gastroparesis by protecting gastrointestinal function in diabetic rats by Jian-zhen Jiang, Wan-qiu Li, Kun-lin Kuang, Yu-qing Jiang, Zhao-xuan He, Li-juan Zhang, Jing-ya Cao, Dan Wang, Xin-yue Zhang, Zi-lei Tian, Jun Zhu, De-zhong Peng

“…These results suggest that tuina’s protective effect on GI function is related to the expression of Piezo2 ion channels.ConclusionsLong-term tuina protects the GI function of DM rats and inhibits the occurrence of DGP, which might be related to the Piezo2/5-HT pathway.…”
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Increased functional connectivity of amygdalar-frontal pathways in patients with alcohol use disorder and childhood trauma by Elisabeth Jehli, Fabienne Burri, Niklaus Denier, Franz Moggi, Andrea Federspiel, Roland Wiest, Maria Stein, Tobias Bracht, Matthias Grieder, Leila M. Soravia

“…Here, we additionally aimed to investigate fronto-limbic functional connectivity (FC) in patients with AUD with (AUD-CT) and without (AUD-noCT) CT. …”
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Identification of biological rhythms related GIGANTEA genes in tomato and functional analysis under heat stress by Xiting Yang, Shuchao Huang, Wei Li, Zhaozhuang Li, Zhiqi Xu, Wenhao Zhou, Xin Meng, Yandong Xie, Shuya Wang, Li Jin, Ning Jin, Jian Lyu, Jihua Yu

“…These findings provide a foundation for further research into its functional role and potential molecular mechanisms of heat tolerance in tomato.…”
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Hypertension, Sarcopenia, and Global Cognitive Function in Community-Dwelling Older Women: A Preliminary Study by Hélio José Coelho-Júnior, Bruno Bavaresco Gambassi, Maria-Claudia Irigoyen, Ivan de Oliveira Gonçalves, Paula de Lourdes Lauande Oliveira, Paulo Adriano Schwingel, Cândida Helena Lopes Alves, Ricardo Yukio Asano, Marco Carlos Uchida, Bruno Rodrigues

“…In conclusion, data of the current study indicate that the sarcopenic state might interfere in the association among hypertension and poor cognitive status, once a higher frequency of hypertensive patients with low lower limb muscle function (i.e., SPPB and sit-to-stand) and muscle mass index (i.e., Janssen index) was observed in the <24 MMSE segment, in comparison with hypertensive patients with normal results in these parameters.…”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…Abstract Background Meta-analyses of observational studies on the effect of dairy on cognitive function have yielded inconclusive results, potentially due to unmeasured confounding. …”
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Sex differences in the association between episodic memory residual reserve index and change in executive function by Cheyenne Chooi, Brandon E. Gavett, David Ames, Paul Maruff, Vincent Doré, Victor L. Villemagne, Pierrick Bourgeat, Ying Xia, Colin L. Masters, Ralph N. Martins, Kevin Taddei, Christopher C. Rowe, Michael Weinborn, Stephanie R. Rainey-Smith

“…Sex differences in cognitive reserve might contribute to females being disproportionately affected by Alzheimer’s disease (AD). …”
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The Functional Polymorphisms of miR-146a Are Associated with Susceptibility to Severe Sepsis in the Chinese Population by Yiming Shao, Jia Li, Yujie Cai, Yuliu Xie, Guoda Ma, You Li, Yanyan Chen, Gen Liu, Bin Zhao, Lili Cui, Keshen Li

“…Our study has analyzed the association of sepsis with two functional miR-146a gene SNPs rs2910164 G/C and rs57095329 A/G in a Chinese Han population (226 sepsis cases; 206 healthy controls). …”
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Android to gynoid fat ratio and its association with functional capacity in male patients with heart failure by Marcelo Rodrigues Dos Santos, Guilherme Wesley Peixoto daFonseca, Letícia Pironato Sherveninas, Francis Ribeiro deSouza, Antônio Carlos Battaglia Filho, Caio Eduardo Novaes, Rosa Maria Rodrigues Pereira, Carlos Eduardo Negrão, Antônio Carlos Pereira Barretto, Maria‐Janieire de Nazaré Nunes Alves

“…Conclusions Body fat distribution, particularly android and gynoid fat composition, together with other cofactors, might have an important adverse role on functional capacity in male patients with HFrEF. …”
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Diaphragm Fatigue Does Not Impact Breathing Mechanics or Function in People with Chronic Low Back Pain by Mitchell UH, Robinson LT, Brinkman J, Bruening DA, Bowden AE, Allen SP

“…Individuals with chronic or recurrent low back pain might therefore be more susceptible to subsequent pain flare-ups than non-symptomatic individuals. …”
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Screening and functional characterization of salt-tolerant NAC gene family members in Medicago sativa L by Zhiguang Li, Qianqian Yu, Yue Ma, Fuhong Miao, Lichao Ma, Lichao Ma, Shuo Li, Huajie Zhang, Huajie Zhang, Zeng-Yu Wang, Guofeng Yang, Guofeng Yang, Kunlong Su

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Impact of rosuvastatin on the memory potential and functionality of CD8+ T cells from people with HIVResearch in context by Federico Perdomo-Celis, Caroline Passaes, Valérie Monceaux, Olivier Lambotte, Dominique Costagliola, Mathieu F. Chevalier, Laurence Weiss, Asier Sáez-Cirión

“…We evaluated the phenotype and functionality of total and HIV-specific CD8+ T cells before, during, and after treatment with rosuvastatin. …”
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Dynamic functional assessment of T cells reveals an early suppression correlating with adverse outcome in polytraumatized patients by Tobias Jooss, Katharina Maier, Lena-Marie Reichardt, Bianca Hindelang, Lönna Süberkrüb, Kim Lena Hamberger, Jasmin Maria Bülow, Konrad Schuetze, Florian Gebhard, Marco Mannes, Rebecca Halbgebauer, Lisa Wohlgemuth, Markus Huber-Lang, Borna Relja, Christian B. Bergmann

“…We assume that the early stimulation of pro- and anti-inflammatory T cells benefits polytraumatized patients. Potentiation of functional IFN-γ release might be achieved by IL-7 administration.…”
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Microstructure changes of the brain preceded glymphatic function changes in young obesity with and without food addiction by Meizhi Yi, Zeng Yule, Weijia Song, Tianyao Wang, Luokai Zhang, Can Hu, Yifeng Peng, Zhaoxiang Zhang, Liangwu Chen, Yan Wang, Huiting Wu, Zhaojie Peng, Xinhua Xiao, Jun Liu, Hong Zhou

“…Conclusions: Widespread WM microstructural abnormalities were detected by NODDI in young obese patients, which might precede changes in brain glymphatic system function. …”
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High-altitude hypoxia exacerbates chemotherapy-induced myelosuppression by lowering serum G-CSF/GM-CSF and regulating apoptosis and proliferation by Jing Shi, Fuxing Zhao, Tianlei Qiu, Dengfeng Ren, Zitao Li, Junli Ma, Jiuda Zhao

“…Transcriptomic analysis of BMNCs demonstrated that high-altitude hypoxia might modulate the hematopoietic function in CTX-induced myelosuppression mice through pathways related to hematopoiesis, such as porphyrin metabolism, hematopoietic cell lineage, ECM-receptor interaction, and PI3K-Akt signaling pathway. …”
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The effect of general versus spinal anesthesia on perioperative innate immune function in patients undergoing total hip arthroplasty by Lotte M. C. Jacobs, Veerle Bijkerk, Lucas T. van Eijk, Leo A. B. Joosten, Christiaan Keijzer, Jetze Visser, Michiel C. Warlé

“…Conclusions General anesthesia has a transient impact on innate immune function in patients undergoing THA, but the clinical significance of anesthesia-induced innate immune dysregulation might be limited as no differences were observed on POD1. …”
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