Artificial plasticenta: how polystyrene nanoplastics affect in-vitro cultured human trophoblast cells by Antonio Ragusa, Loredana Cristiano, Pierluigi Di Vinci, Giuseppe Familiari, Stefania Annarita Nottola, Guido Macchiarelli, Alessandro Svelato, Caterina De Luca, Denise Rinaldo, Isabella Neri, Fabio Facchinetti

“…This would lead to ER and mitochondrial stress, impairing mitochondria/ER functions and oxidative stress, thus activating the apoptotic pathway and suggesting that PS-NPs could act as a cell stressor, leading to the death of cells. …”
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Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress, NF-κB signaling and proinflammatory cytokine production in streptozotoci... by Huan Xiang, Dongxiao Sun-Waterhouse, Chun Cui

“…One mechanism underlying these antidiabetic functions might involve the NF-κB and associated signalling pathways. …”
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Meta-Analysis of Interactions between Arbuscular Mycorrhizal Fungi and Biotic Stressors of Plants by Haishui Yang, Yajun Dai, Xiaohua Wang, Qian Zhang, Liqun Zhu, Xinmin Bian

“…These positive and negative interactions make potential contributions to maintaining ecosystem stability and functioning.…”
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Endocannabinoid System and Synaptic Plasticity: Implications for Emotional Responses by María-Paz Viveros, Eva-María Marco, Ricardo Llorente, Meritxell López-Gallardo

“…Despite the fact that most of the studies on this field have been performed using in vitro models, endocannabinoid-mediated plasticity might be considered as a plausible candidate underlying some of the diverse physiological functions of the endogenous cannabinoid system, including developmental, affective and cognitive processes. …”
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R-Ras regulates migration through an interaction with filamin A in melanoma cells. by Joanna E Gawecka, Genevieve S Griffiths, Barbro Ek-Rylander, Joe W Ramos, Michelle L Matter

“…<h4>Conclusions</h4>These data support a model in which R-Ras functionally associates with FLNa and thereby regulates integrin-dependent migration. …”
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The Relationship Between Reduced Hand Dexterity and Brain Structure Abnormality in Older Adults by Anna Manelis, Hang Hu, Skye Satz

“…Conclusions: Our findings suggest that the 9HPT for hand dexterity might be a cost-effective screening tool for early detection of neuroinflammatory and neurodegenerative processes. …”
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Identification of heterogeneity and common characteristics in colorectal carcinoma located in distinct sites by Yuqi Luo, Yiwen Huang, Yanbo Luo, Yating Yin, Peter Wang

“…Furthermore, GZMB and IER3 might be potential targets for CRC therapy.…”
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Nausea and Vomiting of Pregnancy in Saudi Females: A Cross-Sectional Study by Nora A. Alkhudair, Ziyad Alrabiah, Rana Almohaimeed, Fowad Khurshid, Abdulaziz Alhossan

“…About 58 % of the women reported that they might never consider getting pregnant again because of NVP. …”
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The Potential of Vaccines for the Control of AIDS by Margaret I Johnston, Patricia E Fast, Mary Clare Walker, Daniel Hoth

“…On the other hand. therapeutic administration of a vaccine to an individual in whom infection is already established might benefit the individual by augmenting existing functional immune responses or inducing new ones. …”
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LCK as a Potential Therapeutic Target for Acute Rejection after Kidney Transplantation: A Bioinformatics Clue by Linpei Jia, Rufu Jia, Yinping Li, Xiaoxia Li, Qiang Jia, Hongliang Zhang

“…Then, Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were done to explore the biological functions and potential important pathways of DEGs. …”
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A Novel Splice-Site Variation in COL5A1 Causes Keratoconus in an Indian Family by Qinghong Lin, Lin Zheng, Zhengwei Shen, Liming Jie

“…This mutation might affect the assembly of the collagen triple helix. …”
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Integrating network pharmacology and experimental validation to explore the mechanism of Yiqi Ziyin in treating immune thrombocytopenia by Jun Wang, Bo Wang, Yun Zhang, Li-qiang Wu

“…The ITP-related targets were screened by GeneCards and DisGeNET databases. Then, functional enrichment analyses were conducted to examine the potential regulatory pathways of YQZY in ITP, which was validated by western blot assay. …”
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The human medial temporal lobe represents memory items in their ordinal position in both declarative and motor memory domains. by Ainsley Temudo, Nina Dolfen, Bradley R King, Genevieve Albouy

“…However, it remains unclear whether the functional role of these overlapping brain regions - and the hippocampus in particular - is domain-general. …”
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GALECTIN-3 LEVEL IN pATIENTS WITH mETAbOLIC SYNDROmE AND CORONARY HEART DISEASE by O. М. Drapkina, R. N. Shepel, Т. A. Deeva

“…There were positive correlations  of galectin-3  and CHD functional class  by NYHA (r=0,346, р=0,012): in absence of CHD signs galectin-3 level was 1,05±0,26 ng/mL; in CHD of 1 functional class  (FC) — 1,06±0,18  ng/mL; 2 FC — 1,7±1,59  ng/mL; 3 FC — 2,15±1,85 ng/mL.Conclusion. …”
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The Influence of Fenugreek Seed Powder Addition on the Nutritional, Antioxidant, and Sensorial Properties of Value-Added Noodles by Zulfiqar Ahmad, Muhammad Ilyas, Kashif Ameer, Muhammad Asif Khan, Muhammad Waseem, Faiz-ul-Hassan Shah, Tahir Mehmood, Muhammad Adil Rehman, Isam A. Mohamed Ahmed

“…Conclusively, supplementing dehydrated FSP in the development of value-added foods could improve its functional features. It could also be considered as a plausible source of fibers and proteins, which might be helpful in mitigating malnutrition and a number of health maladies, such as cancer and diabetes.…”
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Who understands and how? – exploring nurses’ perceptions of the readability and usability of instructions written by hospital pharmacists by Henri Satokangas, Kirsi Kvarnström, Hanna M. Tolonen

“…This study focuses on identifying usability and functionality of instructional materials on medicine handling and use produced by hospital pharmacists. …”
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CDK5 interacts with MST2 and modulates the Hippo signalling pathway by Mehak Passi, Jan B. Stöckl, Thomas Fröhlich, Simone Moser, Angelika M. Vollmar, Stefan Zahler

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Circular RNA HIPK3 mediates epithelial–mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs by Yalan Feng, Fan Yang, Jijia Zheng, Lijun Shi, Tianhua Xie, Yunzhi Lin, Qian Shi

“…The functions of circRNAs in mediating EMT has been reported in several diseases. …”
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The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy. by Mauro Savino, Daniela Annibali, Nicoletta Carucci, Emilia Favuzzi, Michael D Cole, Gerard I Evan, Laura Soucek, Sergio Nasi

“…How to target Myc is less clear, given its involvement in a variety of key functions in healthy cells. Here we report on the action mechanism of the Myc interfering molecule termed Omomyc, which demonstrated astounding therapeutic efficacy in transgenic mouse cancer models in vivo. …”
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Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. by Xuting Wang, Brian N Chorley, Gary S Pittman, Steven R Kleeberger, John Brothers, Gang Liu, Avrum Spira, Douglas A Bell

“…As a first step in applying functional genomic analysis to population studies, we have examined the relationship between gene expression variation and genetic variation in a central molecular pathway (NRF2-mediated antioxidant response) associated with smoking exposure and lung cancer. …”
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