CDK12 Promotes Cervical Cancer Progression through Enhancing Macrophage Infiltration by Bikang Yang, Jing Chen, Yincheng Teng

“…In vitro and in vivo functional experiments showed that knockdown of CDK12 inhibited cancer cell proliferation and colony formation and promoted apoptosis. …”
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Aberrant DNA hypermethylation-regulated long non-coding RNA RYR3-DT affects ferroptosis and progression of glioma cell through the CoQ10/FSP1 axis by Yang Cui

“…This investigation found that RYR3-DT was markedly elevated in gliomas. In-vitro functional assays, including Transwell assay, CCK-8, Western blot, and Annexin V assay, revealed that RYR3-DT silencing inhibits glioma cells growth, migration, and invasion, while stimulated cellular apoptosis. …”
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Integrating the metabolic and molecular circuits in diabetes, obesity and cancer: a comprehensive review by Shrikirti Anand, Trupti N. Patel

“…We also attempt to describe the functional disruptions of DNA repair mechanisms due to overwhelming oxidative DNA damage caused by diabesity. …”
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Intersectoral Collaboration in Healthcare: an Overview of International Practices by Yu. Yu. Snegireva, P. I. Ananchenkova, E. A. Korduban

“…Health promotion and universal health coverage are among the functions of any healthcare system which include public, private and voluntary organizations providing health services to the population. …”
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Vinasses valorization into short-chain fatty acids: microbiome robustness against process variations by Silvia Greses, Mercedes Llamas, Aboudi Kaoutar, Cristina González-Fernández

“…The similar bioconversion obtained despite the different microbiomes developed after each perturbation suggested a functional redundancy highlighting the AF robustness. …”
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Beyond awareness: the binding of reflexive mechanisms with the conscious mind: a perspective from default space theory by Ravinder Jerath, Connor Beveridge

“…How do reflexes operate so quickly with so much multimodal information on the environment? How might unconscious processes help reveal the nature of consciousness? …”
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The Use of Slang Word in the Movie “F9: The Fast Saga†by Jeane Theresia Limeranto, Ouda Teda Ena

“…These types of slang have specific functions and meaning to express ideas, thought, expression, and opiniton. …”
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Acoustic structure and information content of trumpets in female Asian elephants (Elephas maximus). by Evelyn Fuchs, Veronika C Beeck, Anton Baotic, Angela S Stoeger

“…Non-linear phenomena prevailed and varied in abundance among individuals, suggesting that irregularities in trumpets might enhance the potential for individual recognition. …”
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Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans. by Anne-Katrin Rohlfing, Yana Miteva, Sridhar Hannenhalli, Todd Lamitina

“…Together, our data suggest infection and osmotic adaptation share previously unappreciated transcriptional similarities which might be controlled via regulation of tissue-specific GATA transcription factors.…”
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Keys to Resilience at ANU: An Exploration Into Student Resilience Approaches and Needs by Melissa Pech

“…This project explored the range of ways students engage their own skills to foster resilience and how these might be supported by their institution of study. …”
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Collapse and Transformation? Cuba, Puerto Rico and the Energy Crisis of “Showcase” Peripheries in World-Ecological Perspective by Roberto J. Ortiz

“…Lastly, the article reflects on the ways in which the ongoing crises—and the respective responses taking place in Puerto Rico and Cuba—might prefigure some of the dilemmas that will characterize future world-ecological trajectories. …”
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The crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice by Yujun Hou, Wen Wang, Jiangnan Ye, Luqiang Sun, Siyuan Zhou, Qianhua Zheng, Yunzhou Shi, Ying Chen, Junpeng Yao, Lu Wang, Xiangyun Yan, Renhong Wan, Shuai Chen, Ying Li

“…NETs formation is pivotal in Indomethacin-induced gastric injury, contributing to programmed cell death of GECs and inflammation; IL-17 signaling might be the key intracellular mechanism of NETs formation.…”
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The relationship between neurofilament light chain and depressive symptoms according to cognitive status by Federico Bellelli, Jeremy Raffin, Davide Angioni, Julie Romana, Maria Soto, Julien Delrieu, Philipe De Souto Barreto, for the MAPT/DSA study group

“…Although no significant CDR–NfL interaction was detected, exploratory analyses suggest that plasma NfL might be associated with GDS‐15 scores only among people with a CDR 0.5 (indicative of mild cognitive impairment). …”
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What Does the Anatomical Organization of the Entorhinal Cortex Tell Us? by Cathrin B. Canto, Floris G. Wouterlood, Menno P. Witter

“…Here, we aim to summarize recent anatomical data supporting the notion that the traditional description of the entorhinal cortex as a layered input-output structure for the hippocampal formation does not give the deserved credit to what this structure might be contributing to the overall functions of cortico-hippocampal networks.…”
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Learning selection-based augmented reality interactions across different training modalities: uncovering sex-specific neural strategies by John Hayes, Joseph L. Gabbard, Ranjana K. Mehta

“…We analyzed brain activation and functional connectivity using functional near-infrared spectroscopy during the evaluation phase. …”
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A Vehicular Cyber-Physical Framework for Studying the Effects of Multiple Disturbances with Application to Connected Autonomous Vehicles by Mohammed Amir, Marine Lincoln, Ramlal Craig, Muddeen Fasil

“…These systems underpin critical infrastructures (CIs), which require coordination to achieve societal functions. However, the exponential growth of CPSs brings about a new challenge as it relates to the security of such systems and by extension any disturbances which might affect their operation. …”
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The personalized telemedical system of Obereg for remote patient's monitoring by A. A. Eremenko, N. V. Rostunova, S. A. Budagyan, A. V. Kurnosov

“…The operability of the system has been confirmed in clinical conditions for patients of various profiles, including the most severe cases; it was found that the functionality of the system and accuracy of measurement met relevant requirements. …”
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Presynaptic Glycine Receptors Increase GABAergic Neurotransmission in Rat Periaqueductal Gray Neurons by Kwi-Hyung Choi, Michiko Nakamura, Il-Sung Jang

“…The glycine-induced increase in sEPSC frequency completely disappeared either in the presence of tetrodotoxin or Cd2+, voltage-gated Na+, or Ca2+ channel blockers, suggesting that the activation of presynaptic glycine receptors might depolarize excitatory nerve terminals. The present results suggest that presynaptic glycine receptors can regulate the excitability of PAG neurons by enhancing glutamatergic transmission and therefore play an important role in the regulation of various physiological functions mediated by the PAG.…”
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Conception and usability pilot study of a new digital cognitive screening tool on tablet: AlzVR project by Florian Maronnat, Guillaume Loup, Jonathan Degand, Frederic Davesne, Samir Otmane

“…Composed of seven tasks inspired by the Mini-Mental Status Examination and the Montréal Cognitive Assessment, it browses several cognitive functions. The architectural design of this tablet application is distinguished by its multifaceted capabilities, encompassing not only seamless offline functionality but also a mechanism to ensure the singularity of data amalgamated from diverse sites. …”
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Efektifitas Pelaksanaan Corporate Governance dan Audit Eksternal Auditor dengan Spesialisasi Industri dalam Menghambat Manajemen Laba by Antonius Herusetya

“…While in our other tests using the external audit- one of the functions of the gatekeeper of capital market, The Big 4 auditors (both with and without industry specialization) and non- Big 4 auditors could not provide any evidence that these gatekeepers functioned effectively to detect opportunistic earnings management. …”
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