YEATS2 promotes malignant phenotypes of esophageal squamous cell carcinoma via H3K27ac activated-IL6ST by Yuanfang Zhai, Yuanfang Zhai, Fanyu Zhang, Fanyu Zhang, Xiaoyu Shi, Xiaoyu Shi, Siwei Zou, Siwei Zou, Xiaoling Hu, Xiaoling Hu, Chengyuan Shan, Chengyuan Shan, Ling Zhang, Binbin Zou, Xin Yang, Pengzhou Kong, Xiaolong Cheng

“…Additionally, YEATS2 could recruit TAF15 and KAT5 to enhance H3K27ac enrichment in the promoter region of IL6ST to regulate its expression.ConclusionIn conclusion, YEATS2 might function as a potential driver gene and a potential therapeutic target in ESCC.…”
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Identification of Plasma Exosomes hsa_circ_0001360 and hsa_circ_0000038 as Key Biomarkers of Coronary Heart Disease by Wan Zhang, Jiasen Cui, Li Li, Ting Zhu, Zhenyu Guo

“…Hsa_circ_0001360 combined with hsa_circ_0000038 might be an important diagnostic biomarker.…”
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Astrocytes carrying LRRK2 G2019S exhibit increased levels of clusterin chaperone via miR-22-5p and reduced ability to take up α-synuclein fibrils by Alice Filippini, Giulia Carini, Alessandro Barbon, Massimo Gennarelli, Isabella Russo

“…Abstract Accumulating evidence highlights that dysfunction of astrocyte biology might contribute to Parkinson’s disease (PD) onset and progression. …”
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The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target. by Bo Wu, Jacopo Novelli, Jeremy Foster, Romualdas Vaisvila, Leslie Conway, Jessica Ingram, Mehul Ganatra, Anita U Rao, Iqbal Hamza, Barton Slatko

“…This approach enables functional complementation in E. coli heme deficient mutants as an alternative E. coli-based method for drug screening.…”
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Genomic analysis and characterization of lytic bacteriophages that target antimicrobial resistant Escherichia coli in Addis Ababa, Ethiopia by Tamirat Salile Sada, Dawit Hailu Alemayehu, Kalkidan Melaku Tafese, Tesfaye Sisay Tessema

“…Because of their stringent lytic nature, these phage isolates might be used in the future to treat E. coli infections. …”
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Clinical usefulness of hemoencephalography beyond the neurofeedback by Serra-Sala M, Timoneda-Gallart C, Pérez-Álvarez F

“…It is available to any research group for its relative simplicity and low cost and is a useful tool for assessing prefrontal-dependent functions. Older teenagers pose peculiarities in the prefrontal maturation, and we aim to establish HEG patterns that might have clinical applicability. …”
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Involvement of circadian clock protein PER2 in controlling sleep deprivation induced HMGB1 up-regulation by targeting p300 in the cortex by Min Zhang, Zhuoyao Ma, Haoran Cui, Yumeng Miao, Yu Yin, Qing Wen, Zhihui Liu, Xin Huang, Chen Xing, Kun Liu, Hui Peng, Lun Song

“…Circadian disorders induced by sleep deficit might contribute to the development of neuroinflammation. …”
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Children’s and Their Parents’ Experiences With Home-Based Guided Hypnotherapy: Qualitative Study by Ilse N Ganzevoort, Adriëlla L van der Veen, Manna A Alma, Marjolein Y Berger, Gea A Holtman

“… Abstract BackgroundManagement of children with functional abdominal pain (FAP) or irritable bowel syndrome (IBS) is difficult in primary care. …”
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Gastric Carcinoid Tumours and Pernicious Anemia: Case Report and Review of the Literature by Sarah Hagarty, Istvan Hüttner, Henry Shibata, Saul Katz

“…The frequent occurrence of gastric carcinoid tumours in patients with long-standing pernicious anemia suggests that surveillance gastroscopy and biopsies of the fundus might be indicated. Compete functional antrectomy may effectively cause these tumours to regress by removing their excessive gastrin hormonal stimulation. …”
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Le texte et l’image dans la formulation de la preuve en physique des matériaux by Catherine Allamel-Raffin

“…First, I will focus on the functions of images and text as the researchers defined them. …”
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Autism in Norwegian Criminal Justice by Lucie Margot Ducarre, Linda Gröning, Kari Øverland

“…Autism is a neurodevelopmental condition characterised by differences in communication, social interactions, sensory processing, and cognitive functioning. While these features might have important legal and forensic relevance, research on the understanding and bearings of autism in criminal justice remains scarce. …”
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L’écriture cinématographique de la sociologie filmique. Comment penser en sociologue avec une caméra ? by Pierre Maillot

“…Firstly, participants needed to know about their tools’ functions and how these might be wielded. After all, the only people who can film or take pictures are photographers or cinematographers. …”
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Sanctionner : parfaire la loi by Guillaume Glénard

“…The conception of the king as co-legislator might account for the various forms of veto, as well as the interpretation of the functions of royal assent in the framework of the Constitution of 1791. …”
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On Some Aspects of the Lilleoru Community by Kaidi Tamm

“…As a result of the study it might be said that although from the outside Lilleoru is mainly seen as an ecovillage, from inside being an awareness training centre is central. …”
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Our connections to soil health through simile by Alan J. Franzluebbers

“…Strong corollaries exist between the functioning of the human body and the soil body. This essay explores these two bodies through simile. …”
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The Immune-Modulatory Role of Apolipoprotein E with Emphasis on Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis by Hong-Liang Zhang, Jiang Wu, Jie Zhu

“…Apolipoprotein E (apoE) is a 34.2 kDa glycoprotein characterized by its wide tissue distribution and multiple functions. The nonlipid-related properties of apoE include modulating inflammation and oxidation, suppressing T cell proliferation, regulating macrophage functions, and facilitating lipid antigen presentation by CD1 molecules to natural killer T (NKT) cells, and so forth. …”
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Religious Participation, Gender Differences, and Cognitive Impairment among the Oldest-Old in China by Wei Zhang

“…Findings indicate that (a) religious participation is significantly correlated with cognitive functioning in part because the religious oldest-old are more likely to be optimistic and happy and engage in more cognitively stimulating activities; (b) there might be gender differences in religious participation such that the oldest-old men may engage in religious activities that are particularly relevant to cognitive functioning.…”
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Sea food by-products valorization for biomedical applications: evaluation of their wound regeneration capabilities in an Ex vivo skin model by Giulia Zivelonghi, Luca Melotti, Anna Carolo, Andrea Venerando, Margherita Roncoroni, Giordana Martinelli, Lisa Maccatrozzo, Stefania Marzorati, Michela Sugni, Marco Patruno

“…IntroductionThe skin is often exposed to harmful stimuli that might compromise its integrity and functionality. …”
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Selected Factors Affecting the Development of Auditing Services Market in Poland by Rafał Rydzak

“…Properly utilized rotation principle, by strengthening the competence, might positively influence functioning of the auditing services market. …”
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Research progress of chondroitin sulfate and chondroitin sulfate proteoglycan in diabetic kidney disease by ZHANG Min, HU Chun, WU Xiao-yan

“…Chondroitin sulfate/chondroitin sulfate proteoglycan(CS/CSPG) is an essential component of ECM, including a large family of biological active molecules with complex structures and various functions. They play important functional and regulatory roles in physiology and pathology. …”
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