Temporal dynamic vulnerability – impact of antecedent events on residential building losses to wind storm events in Germany by A. Trojand, H. W. Rust, H. W. Rust, U. Ulbrich

“…For this purpose, generalized additive models are implemented to estimate vulnerability as a function of the intensity of the previous event and the time interval between the events. …”
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LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1 by Bin Ke, Hai Zhong, Yuxin Gong, Xiaofei Chen, Chenxin Yan, Lin Shi

“…However, the expression, function, and mechanism of LINC00323 in non-small cell lung cancer (NSCLC) are unclear. …”
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miR-424-5p Promotes Proliferation, Migration and Invasion of Colorectal Cancer Cells via the Targeting TXNIP/Hippo Axi by Zhang F, Zhu KL, Chen R, Su F

“…The above findings suggested that miR-424-5p and TXNIP might serve as the potential therapeutic targets for CRC patients.Keywords: CRC, thioredoxin interacting protein, miR-424-5p, YAP/TAZ signaling pathway…”
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Comparison of rapid recovery outcomes between vNOTES hysterectomy and laparoscopic hysterectomy: a prospective study by Ying Tang, Chun-ling Fang, Jun-rong Huang, Xiao-mei Chen, Xin Cai, Jia Wu, Hui-quan Hu, Jun Li, Yue-xi Luo

“…Conclusions and relevance vNOTES in women might be advantageous in the earlier recovery of intestinal function and the earlier return to work after hysterectomy compared with laparoscopy. …”
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Upregulation of long noncoding RNA zinc finger antisense 1 enhances epithelial–mesenchymal transition in vitro and predicts poor prognosis in glioma by Qiao-Li Lv, Shu-Hui Chen, Xue Zhang, Bao Sun, Lei Hu, Qiang Qu, Yuan-Tao Huang, Gui-Hua Wang, Yan-Ling Liu, Ying-Ying Zhang, Hong-Hao Zhou

“…Zinc finger antisense 1 is a novel long noncoding RNA whose clinical significance, biological function, and underlying mechanism are still undetermined in glioma. …”
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Protein interactions, network pharmacology, and machine learning work together to predict genes linked to mitochondrial dysfunction in hypertrophic cardiomyopathy by Jia-lin Chen, Di Xiao, Yi-jiang Liu, Zhan Wang, Zhi-huang Chen, Rui Li, Li Li, Rong-hai He, Shu-yan Jiang, Xin Chen, Lin-xi Xu, Feng-chun Lu, Jia-mao Wang, Zhong-gui Shan

“…Given that Abt-751 had the highest binding affinity to CEBPD, it might be a projected targeted medication. We found a new target gene for HCM called CEBPD, which is probably going to function by mitochondrial dysfunction. …”
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Exploring Molecular Pathways in Refractive Errors Associated with Inherited Retinal Dystrophies by Fabiana D’Esposito, Caterina Gagliano, Alessandro Avitabile, Giuseppe Gagliano, Mutali Musa, Matteo Capobianco, Federico Visalli, Edoardo Dammino, Marco Zeppieri, Maria Francesca Cordeiro

“…However, the prevalence statistics might differ significantly depending on the exact type of dystrophy and the demographic being examined. …”
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Prolonged Honeymoon Period in a Thai Patient with Adult-Onset Type 1 Diabetes Mellitus by Yotsapon Thewjitcharoen, Ekgaluck Wanothayaroj, Haruethai Jaita, Soontaree Nakasatien, Siriwan Butadej, Ishant Khurana, Scott Maxwell, Assam El-Osta, Waralee Chatchomchuan, Sirinate Krittiyawong, Thep Himathongkam

“…The “honeymoon” phase among people with type 1 diabetes mellitus (T1DM) refers to the period (mostly less than 1 year) in which beta-cells remain functional and are able to produce insulin to maintain good glycemic control shortly following the development of diabetes. …”
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Assay of Serum Iron and TIBC: A Preliminary Study for Survey Shortlisting Suspected Tuberculosis Patients by Dipak Kumar Chattopadhyay

“…All the subjects in this study had normal liver function tests and they did not suffer from iron overload diseases or any malabsorption of iron syndrome. …”
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N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells by Jie Lai, Zhiyong Zhou, Kan Hu, HongLong Yu, Xingyao Su, Xiaoqiang Niu, Huizi Li, Shengxun Mao

“…Knockdown of LncRNA ADIRF-AS1 and AL139035.1 promotes CRC progression and might be critical in regulating drug resistance formation.…”
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The Pore Diffusion Coefficient of Iodide Ion in Rock Samples Using X-ray K-edge Imaging by Jiujiang ZHAO, Zhe WANG, Zhidu ZHANG, Hong ZHAO

“…The value of Δμ is a function of the mass of a tracer along the X-ray path. …”
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A new selective force driving metabolic gene clustering by Marco Fondi, Francesco Pini, Christopher Riccardi, Pietro Gemo, Matteo Brilli

“…The formation of clusters of functionally related genes in microbial genomes has puzzled microbiologists since their first discovery. …”
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Investigation of hypoglycemic and antidiarrheal activity on mice model and in vitro anthelmintic study of Macropanax dispermus (Blume) Kuntze (Araliaceae): a promising ethnomedicin... by Syeda Rubaiya Afrin, Mohammad Rashedul Islam, Sayeda Saima Didari, Sarah Waddun Jannat, Ummah Tasnim Nisat, Mohammed Kamrul Hossain

“…The FTIR spectra demonstrated the presence of different functional groups, which might contribute to the presence of flavonoids, saponins, terpenoids, and other related compounds. …”
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New fungal core microbiome members of the ground nesting bee Andrena vaga: The key to oligolecty? by Hanna Gardein, Silvio Erler, Henri Greil, Andrey Yurkov

“…Other identified yeasts, such as Starmerella bombicola, are discussed in terms of their ecology and functionality. Our study provides insights into the crucial role of associated microorganisms and might be the missing link to understand the origin of oligolecty.…”
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Curcumin Analog J7 Attenuates Liver Fibrosis and Metabolic Dysregulation in a Rat Model of Type 2 Diabetes via Modulation of TGF-β/Smad and NF-κB/BCL-2/BAX Pathways by Ma J, Chen W, Vaishnani DK, Wang C, Xue S, Yang Q, Tong Y, Lei N, Zhao Z, Ying F

“…Diabetic rats were treated with curcumin, low-dose J7, or high-dose J7, and liver function and fibrosis were assessed through biochemical analyses, histopathology, immunohistochemistry, and ELISA.Results: J7 administration significantly improved lisver function, reduced fibrosis, and regulated metabolic profiles in diabetic rats. …”
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Preserved Ratio Impaired Spirometry in US Primary Care Patients Diagnosed with Chronic Obstructive Pulmonary Disease by Evans A, Tarabichi Y, Pace WD, Make B, Bushell N, Carter V, Chang KL, Fox C, Han MK, Kaplan A, Kocks JWH, Le Lievre C, Roussos A, Skolnik N, Soriano JB, Yawn BP, Price D

“…Multivariable logistic regression was performed to assess whether PRISm predicts lung function decline.Results: Prevalence of PRISm within a primary care population clinically diagnosed with COPD was 23.6% (678/2866, 95% CI 22.0– 25.1). …”
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Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy by Zhang M, Wang J, Xue S, Liu S, Li K, Zhao T, Feng Y, Sui R, Yang B, Yang X

“…The majority of the AUVP patients had cardiovascular risk factors and abnormal systemic immunological indicators, which might be the possible etiologies of AUVP.Keywords: acute unilateral peripheral vestibular dysfunction, etiology, vestibule, labyrinth, vestibular nerve…”
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BRD4 acts as a transcriptional repressor of RhoB to inhibit terminal erythropoiesis by Yijin Chen, Dawei Huo, Ye Meng, Jie Zhang, Mengmeng Huang, Qian Luo, Yulin Xu, Haiqiong Zheng, Yingli Han, Xiangjun Zeng, Yanjuan Liu, Yunfei Liu, Rui Wen, Delin Kong, Ruxiu Tie, Shanshan Pei, Nan Liu, Pengxu Qian, He Huang, Meng Zhang

“…Besides, we clarify RhoB’s activity and function during terminal erythropoiesis. BRD4 inhibition might be a simple method to promote in vitro blood cell production, and a candidate therapeutic target for diseases leading to dyserythropoiesis such as myelodysplastic syndromes.…”
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A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

“…The ceRNA network associated with NSCLC was identified, and the hub genes, circRNAs, might act as the potential biomarkers for NSCLC.…”
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Myocardial dysfunction caused by MyBPC3 P459fs mutation in hypertrophic cardiomyopathy: evidence from multi-omics approaches and super-resolution imaging by Yupeng Wu, Yupeng Wu, Yuzhu Zhang, Yuzhu Zhang, Qirui Zheng, Qirui Zheng, Qiyuan Wang, Qiyuan Wang, Xingyu Fang, Xingyu Fang, Zaihan Zhu, Zaihan Zhu, Jing Lu, Dandan Sun, Dandan Sun

“…These findings provided a link between the observed structural and functional disorders in MyBPC3 P459fs mutation and its onset of HCM pathogenesis and might have a significant translational contribution to effective treatment in HCM patients with MyBPC3 P459fs mutation.…”
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