Metal oxides on the frontlines: Antimicrobial activity in plant-derived biometallic nanoparticles by Krishnan Anbarasu, Sathishkumar Kuppusamy, Devi Okram Ricky, Agrawal Smita, Debnath Abhijit, Arasu Mariadhas Valan, Sundaram Thanigaivel, Subramanian Kumaran, Karunakaran Rohini

“…Plant-derived biomaterials and metal oxides work harmoniously to provide a new dimension in materials science that might lead to ground-breaking applications in environmental remediation and biomedicine. …”
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Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathway by Jian Wang, Xin Lv, Yao Lin, Ashanjiang Aniwan, Hongyan Liu, Saijun Zhou, Pei Yu

“…Additionally, Genistein protected against increased peritoneal thickness, fibrosis, and angiogenesis, while improving peritoneal function. Based on our results, it could be inferred that Genistein might inhibit the abundance of HIF-1α via the mTOR/OGT pathway, thereby ameliorating MMT as well as fibrosis in PD.…”
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The Distribution of Sport Performance Gene Variations Through COVID-19 Disease Severity by Guven Yenmis, Ilayda Kallenci, Mehmet Dokur, Suna Koc, Sila Basak Yalinkilic, Evren Atak, Mahmut Demirbilek, Hulya Arkan

“…Notably, recent studies have highlighted the role of genes associated with athletic performance, such as ACE, ACTN3, and PPARGC1A, in influencing muscle function, cardiovascular health, and the body’s metabolic response. …”
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Evidence for direct dopaminergic connections between substantia nigra pars compacta and thalamus in young healthy humans by Giovanni Cirillo, Giuseppina Caiazzo, Federica Franza, Mario Cirillo, Michele Papa, Fabrizio Esposito

“…The substantia nigra pars compacta (SNc), one of the main dopaminergic nuclei of the brain, exerts a regulatory function on the basal ganglia circuitry via the nigro-striatal pathway but its possible dopaminergic innervation of the thalamus has been only investigated in non-human primates. …”
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The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies. by Richard T Davey, Ruth Lynfield, Dominic E Dwyer, Marcello H Losso, Alessandro Cozzi-Lepri, Deborah Wentworth, H Clifford Lane, Robin Dewar, Adam Rupert, Julia A Metcalf, Sarah L Pett, Timothy M Uyeki, Jose Maria Bruguera, Brian Angus, Nathan Cummins, Jens Lundgren, James D Neaton, INSIGHT FLU 002 & 003 Study Groups

“…It is conceivable that interventions designed to abrogate these baseline elevations might affect disease outcome.…”
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The effect of fear of movement on gait characteristics in patients with knee osteoarthritis by Bixuan Duan, Yuxuan Zhang, Pei Ma, Fangmin Chen, Wei Li

“…Conclusion High-fear KOA patients might perform a protective movement strategy, which may lead to asymmetry in movement patterns by reducing weight bearing on the affected side. …”
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Adaptive cognitive control in 4 to 7-year-old children and potential effects of school-based yoga-mindfulness interventions: an exploratory study in Italy by Lisa Toffoli, Giulia Stefanelli, Giulia Manca, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Michele Guidi, Francesca Incagli, Luca Sbernini, Luca Sbernini, Vincenza Tarantino, Giovanni Mento, Giovanni Mento

“…Moreover, they successfully modulate interference control as a function of environmental contingencies, displaying more optimal conflict resolution when proactive control is engaged. …”
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Efficacy of virtual reality balance training on rehabilitation outcomes following anterior cruciate ligament reconstruction: A systematic review and meta-analysis. by Chao Du, Nei-Meng Gu, Tian-Ci Guo, Ai-Feng Liu

“…In the rehabilitation training following ACLR and lower-limb balance training, the application of VR might be advantageous for the recovery of patients' knee joint function, lower-limb muscle strength, proprioception, and pain management. …”
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Dissatisfaction Risk Factors of Patients after Laminectomy for Thoracic Ossification of Ligamentum Flavum: A Retrospective Cohort Study of Different Follow-Up Periods by Zhiwei Wang, Sidong Yang, Xianda Gao, Zheng Wang, Wenyuan Ding, Dalong Yang

“…The JOA scores of patients in the satisfied group and the dissatisfied group increased gradually with the improvement of neurological function in different follow-up periods, but, at the last follow-up, the JOA scores of patients in the satisfied group were significantly higher than those in the dissatisfied group. …”
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Time series analysis combined with transcriptome sequencing to explore characteristic genes and potential molecular mechanisms associated with ultrasound-guided microwave ablation... by Qian Zhang, Guangfei Yang, Ruijiao Chang, Fuxia Wang, Tao Han, Jin Tian, Wen Wang

“…The expression of marker genes was validated by quantitative real-time polymerase chain reaction (qRT-PCR).Results Five marker genes (IL32, VCAM1, IL34, NFKB1 and CXCL13) were identified, which were connected with immune-related functions. Two immune checkpoints (CD96 and TIGIT) and six inflammatory factors played key roles in US-guided MWA for glioma. ceRNA regulatory networks revealed that miR-625-5p, miR-625-3p, miR-31-5p and miR-671-5p were associated with target genes. qRT-PCR indicated both IL32, VCAM1, and NFKB1 were potential markers under US-guided MWA-related time series analysis.Conclusion The use of US-guided MWA might be a practical method for influencing the function of target genes, regulating time frames to decrease inflammation, and stimulating immune responses in glioma therapy.…”
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Exploring causal relationships between brain imaging-derived phenotypes and ovarian cancer risk: a bidirectional Mendelian randomization by Ting Liu, Xiaoqian Tuo, Huifang Zhao, Yan Wang, Yu Jiang, Jiaojiao Lu

“…Abstract Background Ovarian cancer could induce alterations in both structure and function of the brain. This study employs Mendelian randomization (MR) to investigate the causal relationship between brain imaging-derived phenotypes (IDPs) and ovarian cancer, offering new insights into the potential clinical applications of IDPs for ovarian cancer risk assessment. …”
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Risk factors for venous thromboembolic events in patients with rheumatoid arthritis by M. A. Satybaldyeva, T. M. Reshetnyak, N. V. Seredavkina, S. I. Glukhova, D. E. Karateev, E. L. Nasonov

“…There was a questionnaire survey that included traditional risk factors for VTEE and risk factors that might be due to RA and its therapy.Results and discussion. 34 (9.9%) patients were found to have VTEE during their hospitalization or in their history. …”
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HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modification by Enshuang Guo, Lei Li, Jiankun Yang, Yongjian Zhou, Lu Bai, Weiwei Zhu, Qiuyue Hu, Huifen Wang, Hongqiang Liu

“…Results We confirmed that HOXB4 was downregulated in hepatocellular carcinoma tissues and lower HOXB4 expression associated with poor prognosis. Gain- and loss-of function experiments were performed to understand the functional consequences. …”
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Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs by Jiang Zhao, Qian Zhang, Cunle Zhu, Wu Yuqi, Guohui Zhang, Qianliang Wang, Xingyou Dong, Benyi Li, Xiangwei Wang

“…Abstract Objectives Bladder cancer (BLCA) is a tumor that affects men more than women. The biological function and prognostic value of androgen-responsive genes (ARGs) in BLCA are currently unknown. …”
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A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response by Minghan Li, Chang Su, Qianru Wang, Yuetong Chen, Di Jiang, Weijia Wang, Shunjin Chen, Xiangping Li, Ming Fu, Juan Lu

“…Abstract The zinc finger protein 32 (ZNF32) has been associated with high expression in various cancers, underscoring its significant function in both cancer biology and immune response. …”
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The role of the genetic factor of lactate transport in endurance sports by Rafia Fathi, Abdul Al Majidi, Khamael Nhab, Rehab Ramadhan, Ratko Pavlović

“…There are specific changes in genes involved in athletic performance that might play a crucial role in discriminating between excelled athletes and other average athletes. …”
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Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report by Aya Kawasaki, MD, Hidefumi Tonoki, MD, PhD, Osamu Sasaki, MD, PhD, Yoko Matsushita, MD, PhD, Michiko Watari, MD, PhD, Nobuhiro Takahashi, MD, Satoko Fujieda, MD

“…We hope that this case report might help clinicians and genetic counselors manage individualized surveillance plans for patients with TS.…”
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Risk factors for fear of falling in stroke patients: a systematic review and meta-analysis by Li Ma, Qi Xie, Juhong Pei, Ling Gou, Yabin Zhang, Juanping Zhong, Yujie Su, Xinglei Wang, Xinman Dou

“…Sensitivity analysis (leave-one-out method) showed that the pooled estimate was stable.Conclusion This meta-analysis indicated that female population, impaired balance ability, lower mobility, history of falls and walking aid in patients with stroke might be at greater risk for FoF. Future studies are recommended to determine other risk factors specific to patients with stroke.…”
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MGP regulates the adipogenic differentiation of mesenchymal stem cells in osteoporosis via the Ca2+/CaMKII/RIP140/FABP3 axis by Xinglang Wang, Yunhui Zhang, Chenhao Xu, Quanfeng Li, Pengfei Ji, Huatao Liu, Yibin Zhang, Jiahao Jin, Zihao Yuan, Miao Yuan, Pei Feng, Yanfeng Wu, Wenjie Liu, Huiyong Shen, Peng Wang

“…In summary, our research has unveiled the regulatory role of MGP/Ca2+/CaMKII/RIP140/FABP3 axis in adipogenic differentiation in MSC and it might be a promising approach for osteoporosis treatment.…”
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Evaluation of Ocular and Systemic Oxidative Stress Markers in Patients with Diabetic Retinopathy by Ana Karen López-Contreras, Diana Esperanza Arévalo-Simental, Fermín Paúl Pacheco-Moisés, María Guadalupe Martínez-Ruíz, Cecilia Olvera-Montaño, Ricardo Raúl Robles-Rivera, Sonia Sifuentes-Franco, Tannia Isabel Campos-Bayardo, Selene Guadalupe Huerta-Olvera, Adolfo Daniel Rodríguez-Carrizalez

“…Proliferative diabetic retinopathy (PDR) is the most severe complication of chronic hyperglycaemi stimulates oxidative stress that changes the retinal basement membrane function and provokes neovascularization, macular edema and retinal detachment. …”
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