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  1. 2441

    A Comparative Study on the Wettability of Two Coal Samples during Deep Burial Metamorphism by Guochao Yan, Longjian Bai, Jianping Feng, Zhiqiang Zhang

    Published 2020-01-01
    “…The zeta potential and DLVO theory analyses of superficial particles and deep coal particles indicate that deep burial metamorphism process might be favorable for bubble-particle collision and attachment, while might be unfavorable for the wetting process oppositely. …”
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  2. 2442

    Circular at the very beginning: on the initial genomes in the RNA world by Yufan Luo, Minglun Liang, Chunwu Yu, Wentao Ma

    Published 2024-12-01
    “…It is likely that an RNA world existed in early life, when RNA played both the roles of the genome and functional molecules, thereby undergoing Darwinian evolution. …”
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  3. 2443

    The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis by Li Yan, Jiang-Han Li, Ai-Li Zhang, He Li, Bo Pang, De-Yang Meng, Qian Fu, Li-Juan Du, Yan Su

    Published 2025-06-01
    “…Conclusion The results of this study suggested that the biomarkers CD28 and PF4 might play a potential role in the pathogenesis of IPF and might have an impact on the prognosis of the disease. …”
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    Article
  4. 2444

    Genome-wide landscape of genetic diversity, runs of homozygosity, and runs of heterozygosity in five Alpine and Mediterranean goat breeds by Sara Pegolo, Vittoria Bisutti, Lucio Flavio Macedo Mota, Alessio Cecchinato, Nicolò Amalfitano, Maria Luisa Dettori, Michele Pazzola, Giuseppe Massimo Vacca, Giovanni Bittante

    Published 2025-03-01
    “…The high levels of ROH identified in some breeds might indicate high levels of inbreeding and a lack in genetic variation, which might negatively impact the animal population. …”
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    Article
  5. 2445

    Dextromethorphan Dampens Neonatal Astrocyte Activation and Endoplasmic Reticulum Stress Induced by Prenatal Exposure to Buprenorphine by Chun-Hua Lin, Pao-Luh Tao, Huey-Jen Tsay, Yao-Chang Chiang, Wei-Tang Chang, Ing-Kang Ho, Feng-Shiun Shie

    Published 2021-01-01
    “…Our findings suggest that prenatal exposure to buprenorphine might instigate long-lasting effects on hippocampal and astrocytic functions. …”
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    Article
  6. 2446

    The Increment of Choroidal Thickness in Euthyroid Graves’ Ophthalmopathy: Is It an Early Sign of Venous Congestion? by Eylem Cagiltay, Fahrettin Akay, Ozgur Demir, Erdinç Aydın, Berkay Akmaz, Baris Pamuk

    Published 2018-01-01
    “…Impaired ocular blood flow may disrupt the retinal microstructure and functions. In this study, we aimed to investigate the macular and choroidal thickness changes in GO compared with healthy subjects. …”
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  7. 2447

    Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes by Alejandro Luarte, Pablo Cisternas, Ariel Caviedes, Luis Federico Batiz, Carlos Lafourcade, Ursula Wyneken, Roberto Henzi

    Published 2017-01-01
    “…Repetitive stress negatively affects several brain functions and neuronal networks. Moreover, adult neurogenesis is consistently impaired in chronic stress models and in associated human diseases such as unipolar depression and bipolar disorder, while it is restored by effective antidepressant treatments. …”
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  8. 2448

    Dietary composition and overlap between cattle and endangered mountain gazelle (Gazella gazella) by Amir Arnon, Torsten Wronski, Maya Lalzar, S. Yan Landau, Ido Izhaki, Dan Malkinson

    Published 2025-06-01
    “…However, competition between livestock and endangered, native ungulates in these areas might impair their functioning as refugia. We used fecal DNA metabarcoding to study the diets of native mountain gazelles (Gazella gazella) and domestic cattle (Bos taurus), in two nature reserves with distinct vegetation types (shrubland vs grassland), and during different seasons. …”
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    Article
  9. 2449

    Single Nucleotide Polymorphisms in MicroRNA Binding Sites: Implications in Colorectal Cancer by Panchalee Bhaumik, Chandrasekhar Gopalakrishnan, Balu Kamaraj, Rituraj Purohit

    Published 2014-01-01
    “…Further we performed expression analysis to shed light on the potential tissues that might be affected by mutation, enrichment analysis to find the metabolic functions of the gene, and network analysis to highlight the important interactions of cancer causing genes with other genes to provide insight that complex network will be disturbed upon mutation. …”
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  10. 2450

    Can dextromethorphan-bupropion reduce mental pain in depressed individuals? A hypothesis-generating overview perspective by Maurizio Pompili, Isabella Berardelli, Denise Erbuto, Filippo Caraci

    Published 2025-03-01
    “…It negatively impacts social interactions and significantly limits daily functioning, ultimately reducing life satisfaction. …”
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  11. 2451

    Genome-wide DNA methylation regulation analysis provides novel insights on post-radiation breast cancer by Jianghuai Ji, Dongguo Li, Xiaoxiao Zhao, Yajuan Wang, Binbing Wang

    Published 2025-02-01
    “…Enrichment analysis revealed that these radiation-associated genes involved diverse biological functions and pathways in BC. Combining epigenetic data, we identified radiation-associated genes whose transcriptional changes might be associated with aberrant methylation. …”
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  12. 2452

    Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells. by Lin Sun, Anthony J St Leger, Cheng-Rong Yu, Chang He, Rashid M Mahdi, Chi-Chao Chan, Hongsheng Wang, Herbert C Morse, Charles E Egwuagu

    Published 2016-01-01
    “…Although IRF8 expression is induced in activated T cells, the functional relevance of IRF8 in T cell-mediated immunity is not well understood. …”
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    Article
  13. 2453

    Evaluation of Study and Patient Characteristics of Clinical Studies in Primary Progressive Multiple Sclerosis: A Systematic Review. by T Ziemssen, S Rauer, C Stadelmann, T Henze, J Koehler, I-K Penner, M Lang, D Poehlau, M Baier-Ebert, H Schieb, S Meuth

    Published 2015-01-01
    “…<h4>Conclusion</h4>Optimal PPMS study methods involve appropriate patient selection, especially regarding the PPMS phenotype and progression rate. Functional composite endpoints might be more sensitive than single endpoints in capturing progression.…”
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  14. 2454

    Association of genetic variants in Wnt signaling pathway with tuberculosis in Chinese Han population. by Xuejiao Hu, Mengqiao Shang, Juan Zhou, Yuanxin Ye, Xiaojun Lu, Chuanmin Tao, Binwu Ying, Lanlan Wang

    Published 2014-01-01
    “…Further epidemiological and functional studies in larger populations are warranted to verify our results.…”
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  15. 2455

    Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate. by Yueh-Fu O Wu, Annamarie T Bryant, Nora T Nelson, Alexander G Madey, Gail F Fernandes, Holly V Goodson

    Published 2021-01-01
    “…Moreover, bioinformatic studies demonstrate that the presence of intrinsically disordered regions is conserved in key +TIPs, implying that these regions are functionally significant. Together, these results indicate that the CLIP-170 induced patches in cells are phase-separated liquid condensates and raise the possibility that the endogenous +TIP network might form a liquid droplet at MT ends or other +TIP locations.…”
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  16. 2456

    Claudin-1 is a p63 target gene with a crucial role in epithelial development. by Teresa Lopardo, Nadia Lo Iacono, Barbara Marinari, Maria L Giustizieri, Daniel G Cyr, Giorgio Merlo, Francesca Crosti, Antonio Costanzo, Luisa Guerrini

    Published 2008-07-01
    “…The epidermis of the skin is a self-renewing, stratified epithelium that functions as the interface between the human body and the outer environment, and acts as a barrier to water loss. …”
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  17. 2457

    Kompetencje późnorzymskiego vicarius Thraciae w VI-VII wieku by Jacek Wiewiorowski

    Published 2010-12-01
    “…As one example shows, before 582 there was also a vicarius Thraciae who was most probably a military commander, others might have performed functions of heads of the army in emergency, when in the last decades of the 6th and 7th centuries Balkan provinces were threatened by the attacks of Avars and Slavs. …”
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  18. 2458

    Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4. by Tobias Schmid, Johanna S Blees, Magdalena M Bajer, Janine Wild, Luca Pescatori, Giuliana Cuzzucoli Crucitti, Luigi Scipione, Roberta Costi, Curtis J Henrich, Bernhard Brüne, Nancy H Colburn, Roberto Di Santo

    Published 2016-01-01
    “…Finally, computational modelling indicated that the flexibility of the disulfide linker might be necessary to exert the biological functions of the compounds, as the inactive compound appeared to be energetically more restricted.…”
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  19. 2459

    Role of the Mucin-2 and Kaiso genes in the social behavior of mice by E. N. Kozhevnikova, K. M. Achasova, V. S. Korostina, E. B. Prokhortchouk, E. A. Litvinova

    Published 2015-12-01
    “…These results suggest that intestinal homeostasis might have a strong impact on the nervous system of the animals. …”
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  20. 2460

    Innovative applications of biochar in nuclear remediation and catalysis by Mojtaba Kordrostami, Ali Akbar Ghasemi-Soloklui

    Published 2025-05-01
    “…Abstract Emphasizing its potential for environmental sustainability, this review investigated how biochar—a carbon-rich material obtained from biomass pyrolysis—might be used into nuclear science and technology. …”
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