Digital Consciousness and Identity by Дахіль Велієв

“…This deeply affects the user’s ability to maintain their productivity, interact with information, and, more broadly, their ability to function in everyday life. Such situations highlight the need for the development and implementation of strategies and policies that consider potential vulnerabilities associated with technology dependence and aim to minimize the negative consequences of such dependence. …”
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The Role of Anti-dengue Virus NS-1 and Anti-protein Disulfide Isomerase Antibodies on Platelet Aggregation in Secondary Dengue Infection by Andhika Rachman, A.R. Harahap, R.M. Widhyasih

“… Aim: to observe the correlation between anti-NS-1 and anti PDI antibodies against platelets function disorder on secondary dengue infection. Methods: 50 patients with secondary DV infection according to WHO criteria were observed by a cross sectional study. …”
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Should Steroid Therapy Be Necessarily Needed for Autoimmune Pancreatitis Patients with Lesion Resected due to Misdiagnosed or Suspected Malignancy? by Wenchuan Wu, Xiuzhong Yao, Chao Lin, Dayong Jin, Dansong Wang, Wenhui Lou, Xinyu Qin

“…All patients underwent liver function, CA19-9, and contrast-enhanced CT and/or MRI. …”
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Proteomics Analysis of the Regulatory Mechanism of the Calcium-Independent Phospholipase A2 Activity of Peroxiredoxin 6 on Beef Tenderization by LIU Jitong, WANG Xinyi, ZHANG Yimin, ZHU Lixian, LIANG Rongrong, MAO Yanwei

“…Interactions existed among some differential proteins, which were mainly enriched in cellular antioxidant defense, ribosome-mediated protein synthesis regulation, and phospholipid functions. It is suggested that inhibiting Prdx6 iPLA2 activity might impact the degradation of myofibrillar proteins by mediating membrane function, energy metabolism, and apoptosis, ultimately accelerating beef tenderization.…”
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Cytokine Signaling in Diabetic Neuropathy: A Key Player in Peripheral Nerve Damage by Zahra Nashtahosseini, Majid Eslami, Elham Paraandavaji, Alireza Haraj, Bahram Fadaee Dowlat, Ehsan Hosseinzadeh, Valentyn Oksenych, Ramtin Naderian

“…This review emphasizes the importance of cytokine signaling in the pathogenesis of DPN and how cytokine-targeted treatments might reduce inflammation, restore nerve function, and improve clinical outcomes for diabetic patients.…”
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Interleukin biomarkers as predictive tools for lupus nephritis grade and disease activity in systemic lupus erythematosus by Dalia S. Saif, shimaa Abdelsattar, Enas S. Zahran, Mohammed Khalil, Sanaa Samir, Hend E. Abo Mansour

“…They are more prevalent in individuals with LN, particularly in cases with high activity index and with more aggressive classes (in renal classes III and IV). These biomarkers might function as indicators for detecting LN activity and as predictors of LN class.…”
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Characterization of the mRNA untranslated regions [UTR] of the Trypanosoma cruzi LYT1 isoforms derived by alternative trans-splicing by César Augusto Ramírez, Julián Camilo Casas, María Isabel Ospina, José María Requena, Concepción J. Puerta

“…The pre-mRNA derived from the LYT1 gene of Trypanosoma cruzi, is processed by alternative trans-splicing, resulting in different mRNAs which code for the isoforms mLYT1 and kLYT1, proteins having differential expression, cellular location and function. The aim of this study was to characterize the 5’ and 3’ UTRs of the LYT1 mRNAs as the initial step towards the objective of identification of the RBPs responsible for their differential expression. …”
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Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity by Ahmed Rakib, Mousumi Mandal, Md Abdullah Al Mamun, Sonia Kiran, Nelufar Yasmen, Lexiao Li, Daniel M. Collier, Jianxiong Jiang, Frank Park, Udai P. Singh

“…Taken together, these results suggest that a genetic deficiency of siglec-E plays a key role in inducing AT inflammation by differentially altering M-MDSCs and CD8+CXCR3+ T cell function and adipogenesis by TRAF3 and Akt signaling in AT.ConclusionOur findings strongly suggest that modulation of siglec-E pathways might have a protective effect at least in part against AT inflammation and metabolic disorders.…”
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Ion-Specific Gelation and Internal Dynamics of Nanocellulose Biocompatible Hybrid Hydrogels: Insights from Fluctuation Analysis by Arianna Bartolomei, Elvira D’Amato, Marina Scarpa, Greta Bergamaschi, Alessandro Gori, Paolo Bettotti

“…In this article, we investigate hybrid hydrogels made of nanocellulose and either amino–polyethylenglycol or sodium alginates and we present two novel results: (1) the biocompatibility of the amino-containing hybrid gel synthesized using a simplified receipt does not require any intermediate synthetic step to functionalize either component and (2) the fluctuation in the second-order correlation function of a dynamic light scattering experiment provides relevant information about the characteristic internal dynamics of the materials across the entire sol–gel transition as well as quantitative information about the ion-specific gel formation. …”
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Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome. by Julian Jehle, Hanna Goerich, Laura Bindila, Beat Lutz, Georg Nickenig, Vedat Tiyerili

“…However, given their short half-life and their autocrine/paracrine mechanism of action, eCB levels in venous blood samples might not reflect arterial or coronary eCB concentrations. …”
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Effectiveness of Cognitive Behavioral Therapy in Managing Painful Temporomandibular Joint Disorders -A Systematic Review of Randomized Clinical Studies by Ravleen Nagi, Vikranth Ravipati, Radhika Thakkar, Maryam Altuhafy, Shehla F. Hashmi, Junad Khan

“…One study reported that CBT might enhance function recovery in myofascial pain patients with limited opening and posture correction.Conclusion The study analysis suggested CBT may reduce damaging thought patterns and cognitive difficulties and be used with the standard treatment of TMDs. …”
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Increased Neutrophil Extracellular Trap Formation in Uremia Is Associated with Chronic Inflammation and Prevalent Coronary Artery Disease by Jwa-Kyung Kim, Chang-won Hong, Mi Jin Park, Young Rim Song, Hyung Jik Kim, Sung Gyun Kim

“…We hypothesized that the NET formation of neutrophils might be changed in end-stage renal disease (ESRD) patients, explaining their higher incidence of coronary artery diseases (CAD). …”
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Cardio-protective effects of salvianolic acid B on oxygen and glucose deprivation (OGD)-treated H9c2 cells by Bin Yang, Chunyan Zheng, Haichu Yu, Rui Zhang, Cong Zhao, Shanglang Cai

“…These results indicated that cardio-protective function of Sal-B might be ascribed to its down-regulatory property on MEG3 expression which hence blocks p53 and triggers AMPK activation in OGD-treated cells.…”
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Thiram-induced ER stress promotes mitochondrial calcium signaling and NLRP3 inflammasome activation in a tissue specific manner by Shah Nawaz, Md. F. Kulyar, Quan Mo, Zhao Zhang, Chuxian Quan, Mudassar Iqbal, El Fatihi Imad, Jiakui Li

“…Thiram, a broadly used dithiocarbamate fungicide, exaggerates endoplasmic reticulum (ER) stress and interferes with mitochondrial function, thus disrupting cellular homeostasis. Here, we intend to identify the molecular actions of thiram at the mitochondrial-associated ER membranes (MAMs) that lead to the induction of ER stress and mitochondrial calcium overload in both liver and bone tissues. …”
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Hippocampal Dendritic Spines Modifications Induced by Perinatal Asphyxia by G. E. Saraceno, R. Castilla, G. E. Barreto, J. Gonzalez, R. A. Kölliker-Frers, F. Capani

“…Perinatal asphyxia (PA) affects the synaptic function and morphological organization. In previous works, we have shown neuronal and synaptic changes in rat neostriatum subjected to hypoxia leading to long-term ubi-protein accumulation. …”
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Feral Hues & Invasive Pigments: Examining nature-based solutions through ecosocial art engaging spontaneous urban vegetation and informal greenspace by Ellie Irons

“…Multisensorial, direct engagement with urban-dwelling plants can help practitioners and participants understand what kinds of maintenance and tending might help improve sentiment around spontaneous urban vegetation and improve its functional benefits for human communities. …”
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Intervertebral Disc-Derived Stem/Progenitor Cells as a Promising Cell Source for Intervertebral Disc Regeneration by Binwu Hu, Ruijun He, Kaige Ma, Zhe Wang, Min Cui, Hongzhi Hu, Saroj Rai, Baichuan Wang, Zengwu Shao

“…It is because of the fact that these therapies are mainly focused on alleviating the symptoms rather than treating the underlying cause or restoring the structure and biomechanical function of the IVD. Accumulating evidence has revealed that the endogenous stem/progenitor cells exist in the IVD, and these cells might be a promising cell source in the regeneration of degenerated IVD. …”
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A new link between insulinoma and congenital glucose-galactose malabsorption by Antonio Prinzi, Jelka Kuiper, Adorée M van der Wiel, Marie-Louise F van Velthuysen, Remco T P van Cruchten, Lodewijk A A Brosens, Wouter W de Herder, Johannes Hofland

“…We hypothesize that SGLT-1 might play a role in the plasticity of pancreatic β-cells and suggest mechanisms through which CGGM patients could potentially have a higher risk of developing insulinoma in adulthood.…”
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Humic acids modify root architecture in Arabidopsis through H+-ATPase-dependent target of rapamycin activation in concert with Ca2+ and ROS signaling by Mirella Pupo Santos, Milan Zupunski, Hiarhi Monda, Jason Gralian, Aletia James, Guido Grossmann, Richard T. Lamar, Daniel Basílio Zandonadi

“…Abstract Background Humic acids (HA) function as plant biostimulants, enhancing plant metabolism by activating the primary proton transport system, which promotes root growth. …”
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Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. by Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi

“…Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. …”
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