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    Improvement of glucose metabolism in middle-aged mice on a high-fat diet by whole-grain highland barley is related to low methionine levels by Chuanxing Feng, Yueting Ge, Bowen Li, Xiangrong Cheng, Xue Tang, Jianjin Zhu, Yuge Jiang, Yonghui Shi, Guowei Le

    Published 2024-09-01
    “…Therefore, this study evaluated the feasibility of HB as a source of methionine-restricted dietary protein and the potential mechanisms. Middle-aged C57BL/6J mice were fed a control diet (CON), a high-fat diet (HFD), a whole-grain HB high-fat diet (HBHF), or a HBHF + methionine diet (HBHFmet) for 25 weeks. …”
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    Body mass index change and estimated glomerular filtration rate decline in a middle-aged population: health check-based cohort in Japan by Rajiv Saran, Yukari Yamada, Tatsuyoshi Ikenoue, Shingo Fukuma, Jennifer Bragg-Gresham, Edward Norton, Daichi Kohmoto

    Published 2020-09-01
    “…The percentage of excess risk of BMI increase (>4%) mediated by three risk factors (blood pressure, haemoglobin A1c and total cholesterol), was 13.3%.Conclusion In the middle-aged Japanese population, both, increase and decrease in BMI were associated with subsequent eGFR decline. …”
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