Mechanisms, diagnosis, and treatment of olfactory dysfunction in rhinosinusitis by Hai Zhu, Siyuan Qu, Mengdan Gong, Yizhen Xiang, Shengqi Gan, Yaoshu Teng, Dong Ye

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Mitochondrial dysfunction in AMI: mechanisms and therapeutic perspectives by Jingle Shi, Yiding Yu, Huajing Yuan, Yan Li, Yitao Xue

“…The aim is to explore the complex mechanisms of mitochondrial dysfunction in AMI and its profound impact on immune dysregulation. …”
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Mechanisms of Perivascular Adipose Tissue Dysfunction in Obesity by Maria S. Fernández-Alfonso, Marta Gil-Ortega, Concha F. García-Prieto, Isabel Aranguez, Mariano Ruiz-Gayo, Beatriz Somoza

“…However, in established obesity, PVAT loses its anticontractile properties by an increase of contractile, oxidative, and inflammatory factors, leading to endothelial dysfunction and vascular disease. The aim of this review is to focus on PVAT dysfunction mechanisms in obesity.…”
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Diaphragmatic dysfunction by J. Ricoy, N. Rodríguez-Núñez, J.M. Álvarez-Dobaño, M.E. Toubes, V. Riveiro, L. Valdés

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Postoperative Pulmonary Dysfunction and Mechanical Ventilation in Cardiac Surgery by Rafael Badenes, Angels Lozano, F. Javier Belda

“…Postoperative pulmonary dysfunction (PPD) is a frequent and significant complication after cardiac surgery. …”
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Failed Weaning from Mechanical Ventilation and Cardiac Dysfunction by Jahan Porhomayon, Peter Papadakos, Nader D. Nader

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Peripheral dysfunctions in neurodegenerative diseases: Mechanisms and contribution to pathogenesis by M.A. Mukhamedyarov, E.O. Petukhova, E.A. Ushanova, D.F. Nurkhametova, A.V. Leushina, A. Palotás, A.L. Zefirov

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Pathogenetic Mechanisms of Organ Dysfunction in Severe Concomitant Trauma by G. V. Bulava

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Pyloric Dysfunction: A Review of the Mechanisms, Diagnosis, and Treatment by Hee Kyong Na, Andrew A. Li, Andres Gottfried-Blackmore, Alexander J. Podboy, Micaela M. Esquivel, Abel A. Joseph, Linda Nguyen, Joo Ha Hwang

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Mechanisms of glutamate metabolic function and dysfunction in vascular dementia by Jiawen Wang, Yingmei Zhang, Ning Tian, Dongshan Ya, Jiaxin Yang, Yanlin Jiang, Xiaoxia Li, Xiaohui Lin, Bin Yang, Qinghua Li, Rujia Liao

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Mechanisms of neuromuscular junction dysfunction in amyotrophic lateral sclerosis by Aydar N. Khabibrakhmanov, Liaisan A. Akhmadieva, Kerim K. Nagiev, Marat A. Mukhamedyarov

“…Furthermore, we report on the dysfunction of perisynaptic Schwann cells and impaired mechanisms of motor neuron and skeletal muscle interaction in ALS, with a focus on reviewed publications on targeting of molecular mechanisms underlying NMJ dysfunction and disruption in ALS. …”
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Mechanisms and therapeutic perspectives of mitochondrial dysfunction of macrophages in periodontitis by Yibing Jia, Zili Li, Pengjie Huang, Yan Wang, Bo Yang

Subjects: “…mitochondrial dysfunction…”
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Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster by Wei Zhang, Rong Zhou, Xinjuan Lei, Mofei Wang, Qinchun Duan, Yuanlin Miao, Tingting Zhang, Xinjie Li, Zhang Zutong, Liyang Wang, Odell D. Jones, Mengmeng Xu, Joseph Bryant, Jianjie Ma, Yingli Liu, Xuehong Xu

“…Autophagic defects in cardiovascular architecture and cellular dysfunction have been linked to both physiological and pathological conditions of the heart in mammals and Drosophila. …”
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Molecular Mechanisms of Cellular Senescence in Age-Related Endometrial Dysfunction by Hiroshi Kobayashi, Mai Umetani, Miki Nishio, Hiroshi Shigetomi, Shogo Imanaka, Hiratsugu Hashimoto

“…The endometrium is essential for reproductive function, supporting implantation and pregnancy through mechanisms such as hormonal responsiveness, immune regulation, and tissue regeneration. …”
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IL-6 and Olfactory Dysfunction: Focus on Changes, Effects, and Mechanisms by Xiao-Yu Song, Ya-Kui Mou, Han-Rui Wang, Yao Wang, Wan-Chen Liu, Ting Yang, Cai-Yu Sun, Chao Ren, Xi-Cheng Song

“…This article reviews the changes and possible mechanisms of IL-6 in various diseases associated with olfactory disorders, with the aim of providing a reference for the clinical application of IL-6 as a biomarker for olfactory disorders and promoting an in-depth exploration of its mechanism in the occurrence and development of olfactory disorders.…”
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Exploring the regulatory mechanisms of reproductive dysfunction in obese patients with PCOS by Jing Cui, Hui Chang, Yunxia Song, Haiyan Wang, Lin Sun

“…Abstract Polycystic ovary syndrome (PCOS) is a complex endocrine disorder often worsened by obesity, leading to chronic inflammation, metabolic dysregulation, and reproductive dysfunction. This study aims to uncover the molecular mechanisms underlying reproductive dysfunction in obese PCOS patients by identifying key regulatory genes, pathways, and immune interactions, with a focus on cross-tissue regulators and potential therapeutic targets. …”
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Molecular mechanisms for pathophysiology and therapy of cardiac dysfunction in heart failure by Dhalla Naranjan S., Elimban Vijayan, Adameova Adriana Duris, Goyal Ramesh K.

“…Extensive work over the past 6 decades in the field of cardiovascular medicine has revealed that haemodynamic, hormonal, metabolic, cellular and molecular mechanisms of heart failure are not only complex but are also dependent upon the type and stage of heart disease. …”
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Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries by Prashin Unadkat, Tania Rebeiz, Erum Ajmal, Vincent De Souza, Angela Xia, Julia Jinu, Keren Powell, Chunyan Li

“…Despite the presentation of similar psychological symptoms, psychological dysfunction secondary to brain injury exhibits markedly lower treatment efficacy compared to injury-independent psychological dysfunction. …”
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Mechanisms of Decidual Dysfunction and Infertility in Endometriosis: Roles of Prostaglandins and SASP by Kazuhiro Tamura, Mikihiro Yoshie, Kazuya Kusama, Atsuya Tsuru

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Myelin dysfunction in aging and brain disorders: mechanisms and therapeutic opportunities by Zhihai Huang, Yulan Zhang, Peibin Zou, Xuemei Zong, Quanguang Zhang

“…We also highlight myelin dysfunction and the underlying mechanisms in the aging brain, as well as in diverse brain disorders and neurological conditions, including neurodegenerative diseases, psychiatric conditions, brain injuries, chemotherapy-related cognitive impairment, and neurological symptoms associated with COVID-19. …”
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