Advanced Doppler Ultrasound Insights: A Multicenter Prospective Study on Healthy Skin by Priscila Giavedoni, Jorge Romaní, Francisco de Cabo, Francisco Javier García-Martínez, Mónica Quintana-Codina, Esther Roè-Crespo, Irene Fuertes de Vega, Xavier Soria-Gili, Rafael Aguayo-Ortiz, Patricia Garbayo-Salmons, Gonzalo Castillo, David Vidal-Sarró, Jordi Mollet, Laura Serra, Carlos Gonzalez, Emilio López-Trujillo, Miquel Just, Marc Combalia, Sebastian Podlipnik, Josep Malvehy, Ximena Wortsman

“…<b>Conclusions:</b> With the used ultrasound equipment, it was uncommon to visualize vessels in healthy skin. When seen, they covered less than 5% of the image with low flow and small size.…”
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Pathway to care, treatment and disease burden of pulmonary arterial hypertension: a real-world survey of physicians and patients in Latin America by Mauricio Orozco-Levi, Rogerio Souza, Ignacio M Bluro, Julia Harley, Jose Luis Hernández Oropeza, Adrian Lescano, Gisela Meyer, Tatiana Pineda, Alicia Ramirez, Mark Small, Angelo Valencia, Tomás Pulido

“…Low usage of risk assessment strategies and PAH-specific combination therapy was seen in Brazil and Mexico. …”
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Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional... by Aditya Kumar Singh, Akshat Mittal, Manvendra Singh Rawat, Sanjay Dalakoti, Anil Kumar Joshi, Pavneesh Kumar Lohan, Chandra Shekhar, Indrajit Das Bhoumik

“…VAS scores indicated less pain in Group I at one month. Complications were low and similar; one reoperation occurred in Group II. …”
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The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021 by Yunhan Shen, Linyan Wang, Yuxin Cui, Bangxun Mao, Grace Loy Ming Hooi, Oluwatobi Idowu, Juan Ye, Tiansheng Zhu

“…Background: Refraction disorders are common eye conditions that cause blurred vision and, if left uncorrected, remain a leading cause of moderate to severe visual impairment worldwide. Despite this, a comprehensive assessment of the associated burden is lacking. …”
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Automated Foveal Avascular Zone Segmentation in Optical Coherence Tomography Angiography Across Multiple Eye Diseases Using Knowledge Distillation by Peter Racioppo, Aya Alhasany, Nhuan Vu Pham, Ziyuan Wang, Giulia Corradetti, Gary Mikaelian, Yannis M. Paulus, SriniVas R. Sadda, Zhihong Hu

“…Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique used to visualize retinal blood flow and identify changes in vascular density and enlargement or distortion of the foveal avascular zone (FAZ), which are indicators of various eye diseases. …”
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Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?– Implications from experimental measurements in young, healthy, and normal... by Nadja Knoll-Pientka, Dorina Schils, Katrin Pasternak, Sandra Czarnetzky, Christoph Jansen, Gertraud Gradl-Dietsch, Jochen Seitz, Eva-Maria Skoda, Lars Libuda, Adam Schweda, Martin Teufel

“…Abstract Anorexia nervosa (AN) is a severe mental disorder, and patients with AN are characterized by a low body weight and a fear of gaining weight. Restoration of body weight to the normal range is one major treatment aim, which can be a challenging process for the patients. …”
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Neocortical layer-5 tLTD relies on non-ionotropic presynaptic NMDA receptor signaling by Aurore Thomazeau, Sabine Rannio, Jennifer A Brock, Hovy Ho-Wai Wong, Per Jesper Sjöström

“…We, therefore, tested in juvenile mouse visual cortex if tLTD relies on non-ionotropic preNMDAR signaling. …”
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Effects of proprioceptive exercise for knee osteoarthritis: a systematic review and meta-analysis by Yaoyu Lin, Debiao Yu, Debiao Yu, Debiao Yu, Xiaoting Chen, Peng Chen, Nan Chen, Bin Shao, Bin Shao, Bin Shao, Bin Shao, Qiuxiang Lin, Qiuxiang Lin, Fuchun Wu, Fuchun Wu, Fuchun Wu, Fuchun Wu

“…For pain assessment, Numerical Rating Scale scores showed a significant improvement [MD = 0.85, 95% CI (0.56, 1.15), I2 = 46%, P &lt; 0.00001]. Notably, Visual Analog Scale scores exhibited a significant reduction, but only in the short-term intervention subgroup (≤8 weeks) [MD = 0.27, 95% CI (0.11, 0.42), I2 = 0%, P = 0.0008], whereas longer interventions (&gt;8 weeks) showed no significant benefit [MD = −0.49, 95% CI (−1.10, 0.11), I2 = 0%, P = 0.11].ConclusionBased on low-certainty evidence, proprioceptive exercise has been demonstrated to be efficacious in improving balance function and overall clinical status in patients with KOA. …”
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Outcomes of chronic pectoralis major rupture repair with implant-free Achilles allograft by Abdul-ilah Hachem, MD, Diego Gonzalez-Morgado, MD, Peio Beristain, MD, Gonzalo Barraza, MD, Fernando Alvarado, MD, Karla Bascones, MD, Amr Elmaraghy, MD, Xavi Rius, MD

“…These outcomes included the American Shoulder and Elbow Surgeons score, visual analog scale for pain, Constant score, and subjective shoulder value. …”
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Mapping the Epidemiologic Features of Endotracheal Tube ObstructionTake-Home Points by Vimal Bhardwaj, MD, FNB(Critical Care), EDIC, Abhishek Samprathi, MD, DrNB, EDIC, Manu M.K. Varma, MD, DM, Kingshuk Saha, MSc, Ross Prager, MD, John Basmaji, MD, Nicolas Orozco, MD, Srirang Ramamoorthy, MSc, Jose Chacko, MD, EDIC, Arjun Alva, MD

“…Results: Of the 369 ETTs assessed, ETBs were categorized as showing low (0%-9%), moderate (10%-49%), and severe (> 50%) occlusion. …”
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Status of Digital Health Technology Adoption in 5 Vietnamese Hospitals: Cross-Sectional Assessment by Duc Minh Tran, Nguyen Thanh Dung, Chau Minh Duc, Huynh Ngoc Hon, Le Minh Khoi, Nguyen Phuc Hau, Duong Thi Thu Huyen, Huynh Thi Le Thu, Tran Van Duc, Lam Minh Yen, C Louise Thwaites, Chris Paton

“… BackgroundDigital health technologies (DHTs) have been recognized as a key solution to help countries, especially those in the low- and middle-income group, to achieve the Sustainable Development Goals (SDGs) and the World Health Organization’s (WHO) Triple Billion Targets. …”
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Hydrogeology and hydrogeochemistry of the Zaeltsovsko-Mochishchensky zone of radon waters in the southern West Siberia by D. A. Novikov, A. F. Sukhorukova, T. V. Korneeva

“…Therefore, such waters are classified as low-radon and moderate-radon mineral waters (according to the classification proposed by N.I. …”
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Enhanced Dermal Delivery of Nanoparticulate Formulation of Cutibacterium acnes Using Sponge Spicules for Atopic Dermatitis Treatment by Jin Y, Zhang C, Jia M, Chen M

“…In vitro cytotoxicity tests showed that NFCA had low toxicity to HaCaT cells (IC50=63.8 mg/mL). The study confirmed that NFCA can activate immune signaling pathways, promoting the high expression of IL-6 and IL-8 in keratinocytes, enhancing TNF-α and IL-1β expression in macrophages, and inducing Th1 and Th17-type immune responses. …”
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Outcomes of Suprapatellar Intramedullary Nail Fixation of Tibial Shaft Fractures in Skeletally Immature Patients by Carlos D. Pargas-Colina, MD, Tori J. Coble, DO, Sara E. Davis, BS, David D. Spence, MD, Jonathan K. Rowland, BS, Derek M. Kelly, MD, Benjamin W. Sheffer, MD

“…Conclusions: Our findings demonstrated that suprapatellar IMN insertion leads to low pain scores and good function in short-term follow-up for adolescent patients treated for tibial shaft fractures. …”
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Development of a prediction model integrating PD-1 and ICOS for early differential diagnosis between autoimmune and viral encephalitis by Kaiyue Xu, Jinjing Jia, Yinghui Duan, Shuying Chen, Xinyi Xiao, Feng Zhu, Xin Wang, Yanzheng Gu, Jingluan Tian, Qun Xue, Qun Xue

“…BackgroundEarly diagnosis and treatment for encephalitis are crucial for improving patient outcomes and reducing the economic burden, especially given the overlapping symptoms and low specificity of auxiliary diagnostic tests between viral encephalitis (VE) and autoimmune encephalitis (AE). …”
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Effectiveness and safety of light therapy for treating primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials by Lin Ang, Eunhye Song, Sunmi Choi, Jihye Kim

“…Emerging evidence suggests that light-based therapies, including low-level light therapy (LLLT) and high-intensity light therapy (HILT), may offer a non-pharmacological approach to managing menstrual pain. …”
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Microbial profile and associated factors of external ocular bacterial and fungal infections in Arba Minch General Hospital: a cross-sectional study by Melat Woldemariam, Addis Aklilu, Aseer Manilal, Masresha Mengistu, Dagimawie Tadesse, Munira Siraj, Ashraf Atef Hatamleh, Bassam Khalid Alnafisi, Akbar Idhayadhulla

“…Abstract External ocular infections are of serious global concern, which cause significant visual morbidity and even blindness, particularly in low-income and resource-limited countries. …”
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Effects of varying longitudinal bending stiffness in running shoes on lower limb biomechanics of elite marathon runners by Hailiang Yang, Hailiang Yang, Yuhui Cai, Kuang Li, Xiangdong Wang, Tao Liu

“…They were tested wearing shoes with three LBS levels: low (LLBS, 0.31 Nm/deg), medium (MLBS, 0.40 Nm/deg), and high (HLBS, 0.48 Nm/deg). …”
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The Effects of a Smartphone App (Feelee) to Enhance Adolescents’ Emotion Regulation Skills in a Forensic Outpatient Setting: Protocol for a Multiple Single-Case Experimental Design... by Merel M L Leijse, Levi van Dam, Thimo M van der Pol, René Breuk, Arne Popma

“…Study strengths include the low-threshold addition, ecological validity, and the use of both quantitative and qualitative research methods. …”
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Berberine alleviates respiratory syncytial virus (RSV)-induced pediatric bronchiolitis and fibrosis via suppressing the HMGB1/TLR4/NF-κB pathway by Yang Jiao, Rui Yang

“…Flow cytometry analyzed apoptosis, while electron microscopy visualized RSV-induced pyroptotic and apoptotic changes. …”
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