Epidemiology and risk factors of Alzheimer’s disease and related dementias in South and Southeast Asia: a systematic review and meta-analysis protocol by Zhahirul Islam, Israt Jahan, Sharmin Sultana, Nowshin Papri, Mantaka Rahman, Imran Hasan, Tamal Saha, Shoma Hayat, Ashiqa Tabassum, Md Abu Jaher Nayeem

“…Forest plots will be used to visualise the findings, and heterogeneity across the included studies will be assessed using the I² and Cochrane’s Q statistics. …”
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A guide to sunflowers: floral resource nutrition for bee health and key pollination syndromes by Salena Husband, Salena Husband, Katarina Cankar, Olivier Catrice, Stan Chabert, Silvio Erler, Silvio Erler

“…This probes the question on defining the quality of floral resources, emphasizing the need for caution when categorizing sunflower as a low quality nutritional resource. This review also outlines the importance of sunflower nectar characteristics (sugar content and volume) and floral morphology (flower pigmentation and corolla length) on pollinator foraging preferences. …”
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Short-term Clinical and Radiographic Outcomes of Transforaminal Full-endoscopic Pars Crisscross Decompression of the Exiting Nerve Root under Local Anesthesia in Adult Isthmic Spon... by Yutaro KANDA, Fumiaki MAKIYAMA, Ryota MIO, Kozaburo MIZUTANI, Masashi KUMON, Saori SOEDA, Masatoshi MORIMOTO, Fumitake TEZUKA, Kazuta YAMASHITA, Koichi SAIRYO

“…The leg pain improved immediately after surgery in all patients and the mean visual analog scale score improved from 8.2 ± 1.3 preoperatively to 1.2 ± 1.1 at 2 weeks postoperatively. …”
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Biportal endoscopic lumbar discectomy surgery in patients with cauda equina syndrome caused by lumbar herniated intervertebral disc: a retrospective multi-center cohort study by Sang-Min Park, Ho-Jin Lee, Hyun-Jin Park, Ki-Han You, Jong-Hun Jung, Samuel K. Cho, Ho-Joong Kim, Jin S. Yeom

“…Conclusion Biportal endoscopic spine surgery is a feasible and effective option for CES, providing significant decompression with minimal tissue damage and a low complication rate.…”
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Pediatric medication management barriers faced by providers serving underserved populations and proposed solutions by Tiranun Rungvivatjarus, Tiranun Rungvivatjarus, Maria Z. Huang, Maria Z. Huang, Britanny Winckler, Britanny Winckler, Erin S. Fisher, Erin S. Fisher, Kyung E. Rhee, Kyung E. Rhee

“…BackgroundWhile families with limited English proficiency and/or low health literacy face increased risks of medication errors, poor medication management, and non-adherence, little is known about the barriers pediatric medical providers experience when educating families on medication use and compliance. …”
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‘It Just Makes Sense to Me’: A qualitative study exploring patient decision‐making and experiences with prostate MRI during active surveillance for prostate cancer by Ryan Sutherland, Cary P. Gross, Xiaomei Ma, Farah Jeong, Tyler M. Seibert, Matthew R. Cooperberg, William J. Catalona, Shellie D. Ellis, Stacy Loeb, Dena Schulman‐Green, Michael S. Leapman

“…Methods We performed a qualitative study consisting of in‐depth, semi‐structured interviews of patients with low‐ and intermediate‐risk prostate cancer managed with active surveillance. …”
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Strategies for Maintaining Balance in Patients with Parkinson’s Disease by A. E. Slotina, Ekaterina S. Ikonnikova, Georgii A. Kotsoev, Alena S. Egunova, Uliana V. Panina, Ekaterina Yu. Fedotova, Elena V. Gnedovskaya, Natalia A. Suponeva

“…Despite clinical assessments suggesting only mild balance impairments and low fall risk in PD patients, stabilometric parameters revealed more significant static balance disorders contributing to fall risk. …”
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A prognostic model integrating radiomics and deep learning based on CT for survival prediction in laryngeal squamous cell carcinoma by Huan Jiang, Kai Xie, Xinwei Chen, Youquan Ning, Qiang Yu, Fajin Lv, Rui Liu, Yuan Zhou, Shuang Xia, Juan Peng

“…Furthermore, the combined model was represented visually through a nomogram to provide personalized estimation of RFS, with its risk stratification capability evaluated using Kaplan-Meier analysis. …”
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Impact of filgotinib on pain control in the phase 3 FINCH studies by Bruno Fautrel, Peter Nash, Arthur Kavanaugh, Peter C Taylor, René Westhovens, Rieke Alten, Janet Pope, Dick de Vries, Chris Watson, Georg Pongratz, Pieter-Jan Stiers, Ken Hasegawa, Shangbang Rao

“…Objective This post hoc analysis of the FINCH 1–3 (NCT02889796, NCT02873936 and NCT02886728) studies assessed specific effects of filgotinib on pain control and their relationship with other aspects of efficacy in patients with rheumatoid arthritis (RA).Methods Assessments included: residual pain responses of ≤10 and ≤20 mm on a 100 mm visual analogue scale (VAS); the proportion of patients who achieved VAS pain responses in addition to remission or low disease activity by Disease Activity Score-28 with C-reactive protein (DAS28-CRP) or Clinical Disease Activity Index (CDAI) criteria.Results Across studies, filgotinib reduced pain from week 2, with responses sustained throughout the studies. …”
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Two-year follow-up of unilateral biportal endoscopy assisted extraforaminal lumbar interbody fusion: how to perform indirect decompression and fusion under endoscopy: a retrospecti... by Takaki Yoshimizu, Sanshiro Saito, Teruaki Miyake, Tetsutaro Mizuno, Ushio Nosaka, Keisuke Ishii, Mizuki Watanabe, Kanji Sasaki

“…Although BE-ELIF was associated with some inferior clinical outcomes, it provided satisfactory results, effective realignment, and a low complication risk.…”
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Participatory action ultrasound imaging in increasing clinician confidence with new approaches to trigger point dry needling of the lateral pterygoid by Andrew Ball, Stephanie Levi, Sara Barrett, Dana Miller, Erin Ball, Jordan Spennato

“…Prior to PAUI, both the clinician-needler and clinician-observer describe low-to-moderate anxiety in the performance of TrPDN of the lateral pterygoid, using a lateral-to-medial approach. …”
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A radiomics-clinical predictive model for difficult laparoscopic cholecystectomy based on preoperative CT imaging: a retrospective single center study by Rui-Tao Sun, Chang-Lei Li, Yu-Min Jiang, Ao-Yun Hao, Kui Liu, Kun Li, Bin Tan, Xiao-Nan Yang, Jiu-Fa Cui, Wen-Ye Bai, Wei-Yu Hu, Jing-Yu Cao, Chao Qu

“…The SHAP analysis further visualized the importance of features, enhancing model interpretability. …”
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A SAM-adapted weakly-supervised semantic segmentation method constrained by uncertainty and transformation consistency by Yinxia Cao, Xin Huang, Qihao Weng

“…Existing weakly-supervised methods often leverage low-level visual or high-level semantic features from networks to generate supervision information for unlabeled pixels, which can easily lead to the issue of label noises. …”
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Multi‐Spatial Voxel‐Scale Modulation of Acupuncture on Abnormal Brain Activity in Migraine Patients Without Aura: A Randomized Study Neuroimaging Trial by Chaorong Xie, Zhiyang Zhang, Yutong Zhang, Xixiu Ni, Yang Yu, Xiaoyu Gao, Mingsheng Sun, Xiao Wang, Ling Zhao

“…TA modulates the neural activity of the default mode network (DMN), visual network (VN), and sensorimotor network (SMN) at the single voxel scale, local voxel scale and global voxel scale, and these changes are correlated with the improvement of the migraine and quality of life. …”
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A high‐resolution 3D atlas of the spectrum of tuberculous and COVID‐19 lung lesions by Gordon Wells, Joel N Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj, Leon Y Perumal, Malcolm Matthew, Robert L Hunter, Hayden Pacl, Jacelyn E Peabody Lever, Denise D Stanford, Satinder P Singh, Prachi Bajpai, Upender Manne, Paul V Benson, Steven M Rowe, Stephan le Roux, Alex Sigal, Muofhe Tshibalanganda, Carlyn Wells, Anton du Plessis, Mpumelelo Msimang, Threnesan Naidoo, Adrie J C Steyn

“…Abstract Our current understanding of the spectrum of TB and COVID‐19 lesions in the human lung is limited by a reliance on low‐resolution imaging platforms that cannot provide accurate 3D representations of lesion types within the context of the whole lung. …”
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Relationship Between the Nasopharyngeal Swab Sampling Method, Nasal Obstruction, and SARS-Cov-2 Positivity by Dogan Cakan, Zeliha Kubra Cakan, Semih Usaklioglu, Yetkin Zeki Yilmaz, Omer Uysal, Hasan Ahmet Ozdogan

“…The consistency of the first and second test results increased in patients without NSD and in patients with low VAS scores [odds ratio (OR)=3.779; p=0.001, OR=2.572; p=0.005, respectively].Conclusion:Nasopharyngeal swab sampling may be affected by nasal congestion and the sampling method. …”
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Symptom variability in outpatients with COPD and validation of the Colombian COPD Symptom Variability Instrument (EPOC-CoVaSy) by Eidelman Antonio González-Mejía, Olga Constanza Uñate-Suárez, Carlos José Bula- Gutiérrez, Yojana Patricia Patiño-Jiménez

“… Introduction: The variability of respiratory symptoms in chronic obstructive pulmonary disease (COPD) is considered to be low or nonexistent. However, some authors state that there may be fluctuations. …”
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Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007–2016 and Mendelian randomization analysis by Hui Wang, Sensen Wu, Dikang Pan, Yachan Ning, Yanhong Fu, Chunjing Feng, Jianming Guo, Zichuan Liu, Yongquan Gu

“…Then, we used restricted cubic splines (RCS) to flexibly model and visualize the relation of predicted ApoB levels with DN risk. …”
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Comparison of percutaneous endoscopic lumbar discectomy (PELD) and unilateral biportal endoscopic (UBE) discectomy in the treatment of far lateral lumbar disc herniation (FLLDH): a... by Liang Li, Jilong An, Lei Guo, Xiuqi Shan, Yapeng Sun, Jiaqi Li, Fei Zhang, Wei Zhang

“…Compared to the UBE group, the PELD group had lower VAS scores for low back pain on the first postoperative day (P < 0.05), but no significant differences were found in alleviating leg pain in patients postoperatively between these two surgical procedures (P > 0.05). …”
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Gut Microbial Signatures in Long COVID: Potential Biomarkers and Therapeutic Targets by Soyoung Oh, Sujin An, Kihyun Park, Soohyung Lee, Yoo Min Han, Seong-Joon Koh, Joowon Lee, Hyerin Gim, Donghyun Kim, Haesook Seo

“…Particular gut bacteria were significantly correlated with certain systemic, gastrointestinal, otolaryngologic, and visual symptoms. Parabacteroides, Eubacterium ventriosum group, and Rothia abundance was correlated with blood biomarkers that influence long COVID development, including total and low-density lipoprotein cholesterol and basophil levels. …”
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