Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana by Yi Yun Tan, Yin Yin Liew, Rachelle R. Q. Lee, Baptiste Castel, Nga Man Chan, Wei-Lin Wan, Yizhong Zhang, Donghui Hu, Persis Chan, Sang-Tae Kim, Eunyoung Chae

“…Using a phenotype-based screen in Arabidopsis thaliana targeting multiple PDS3 intron splice sites, we achieved up to 81% somatic A-to-G editing in primary transformants at a splice acceptor site with NGG PAM, while 35% was achieved for the same target adenine with NGA PAM. …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…Abstract Background Ovarian cancer (OC) progression is one of the commonest cause of female cancer death. While treatments in clinic includes primary surgery and targeted chemotherapy, curative and survival trends in OC have not significantly improved. …”
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Controlled Resistant Hypertension Following A Successful Renal Artery Stenting: A Rare Case Report in A Developing Country by Fatihatul Firdaus Munita, Badai Bhatara Tiksnadi, Januar Wibawa Martha, Margareta Ginanti Ratna

“…The angiography suggested a normal left renal artery, while the right artery had a 95% stenosis on the proximal part. …”
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Biodegradability of SCOBY-derived bacterial cellulose affected by purification methods by Diego Gomez-Maldonado, Diego González Rodríguez, Mireya Valdés Rivera, Mariana Zerón Pontones, Edgar Ulin, Gabriel Vigueras-Ramírez, Maribel Hernández-Guerrero

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Arsenic-induced circASXL1 regulates 16HBE cell proliferation through the P65 signaling axis by Xuefei Yang, Jingwen Tan, Ruihuan Zhao, Tingzhi Duan, Jingchao Yang, Bin Chen, Xinda Yang, Jinhua Wang, Chenglan Jiang, Guanghui Ni, Yanliang Zhang, Yuefeng He

“…Circular RNAs (circRNAs) are critical in various cellular processes and linked to disease due to their highly stable covalent closed-loop structure, making them potential therapeutic targets. …”
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Experimental Study on The Mechanical Properties of Novel Viscous Mass Damper by CAI Yijie, XU Weizhi, WANG Shuguang, DU Dongsheng, SUN Yue

“…The maximum friction force of the NVMD is 14.2 kN, while the minimum friction force is 15.2 kN. The average friction force is 14.6 kN. …”
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Dual-channel Potential Energy Recovery and Load Balancing Methods for Large Hydraulic Excavators by Weiping WANG, Shun LU

“…In addition, on the basis of load-force feedback, some precise closed-loop control methods can be used to achieve accurate load matching.…”
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Study on the Disturbed Mechanical Behavior and Energy Evolution Characteristics of Deep Roof Rock Considering Spatio-Temporal Effects by WANG man, ZHANG Yang, XIE Jing, NIU Zehua, DENG Huchao, YANG Bengao, ZHAO Lijuan, D ING Xiaogang, GAO Mingzhong

“…With the increase of the loading stress level, the elastic modulus decreases, and area of the hysteresis loop shows an obvious positive correlation with the loading stress level. …”
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Experimental Research on Chinese Traditional Style Architecture Dual-lintel–Column Joint Under Alternating Rapid Loads by JinShuang DONG, Yanru GONG, Bin HUANG, Yan SUI, Liang YANG, Longjian LI

“…In the first stage, the loading and unloading curves of the hysteresis loop almost coincided, and the elastic characteristics of the components were notable, with no substantial residual deformation when unloaded to zero. …”
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MRI Compatibility Research of Ultrasonic Motor and Material for DBS Surgical Robot by PENG Renyuan, ZHANG Juzhong, WANG Zhisen, CHU Yuyi, WU Yuwen, PENG Haoran, LIN Jun, YANG Hongbo

“…The motor speed curve in the experiment demonstrated that closed-loop control of both motors maintained consistent performance in MRI and non-magnetic environments. …”
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The noise analysis and multi-physical field coupling study of high-precision SERF atomic gyroscopes by Jiaxin Liu, Xusheng Lei, Yu Yuan, Yizhe Zhou, Haoying Pang, Zhihong Wu

“…By optimizing the detection loop structure, a distinction between the dual-axis signals' response to optical and magnetic fields was achieved—where the optical errors responded similarly, while the response to magnetic noise was opposite. …”
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In Vitro and In Silico Analysis of Entrainment Characterization in Injection Jet-Assisted Fontan Circulation by Arka Das, Ray O. Prather, Anthony Damon, Michael Farias, Alain Kassab, Eduardo Divo, William DeCampli

“…This study describes a mock flow loop model (MFL) designed to quantitatively estimate pulmonary flow entrainment induced by continuous and pulsed flow injections. …”
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Research Progress on Wet Recovery of Zinc Metal from Blast Furnace Smelting Dust by Lijuan JIA, Shaoxiang YANG, Linjie YANG, Jiayu FENG, Shuo CUI, Fang WANG, Yanzhang LIU, Ping NING

“…These efforts aim to achieve high efficiency, low carbon emissions, and economic upgrading of hydrometallurgy, while promoting the resource utilization and sustainable development of metallurgical solid waste. …”
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TCF12 enhances angiogenesis and affects sorafenib response in liver cancer via HIF-1α interaction by Yuanbin Chen, Xiaolong Wang, Jin Chen, Min Dai, Xinyue Zhang, Jie Yin, Xiao He

“… Transcription factor 12 (TCF12), a member of the basic Helix-Loop-Helix (bHLH) protein family, plays a crucial role in regulating cell growth and differentiation. …”
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Using GPS and accelerometer data to precisely record egg laying, incubation and chick hatching of Cinereous Vultures (Aegypius monachus) in-situ by Cornel Cotorogea, Emilian Stoynov, Atanas Grozdanov, Simeon Marin, Hristo Valeriev Peshev, Ivelin Ivanov, Georgi P. Stoyanov

“…This method allows for continuous, remote monitoring, minimizing disturbance to the breeding pairs.The method was derived after a study on Cinereous Vultures in Bulgaria, using data from Ornitela GPS-GPRS transmitters (OT-30 and OT-50 models) deployed with leg-loop harnesses. Transmitters were configured to acquire data at intervals of 600 or 1200 seconds. …”
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Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation by Yu Cao, Minghui Chen, Xinyu Jiao, Shuijie Li, Dong Wang, Yongxuan Zhan, Jiaju Li, Zhongfei Hao, Qingbin Li, Yang Liu, Yan Feng, Ruiyan Li, Hongjun Wang, Mingli Liu, Qiang Fu, Yongli Li

“…Patients with carotid-unstable plaques exhibited elevated plasma concentrations of MD-1 (LY86), while patients with stable plaques demonstrated comparatively lower levels. …”
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Angiotensin Ⅱ type 1 receptor autoantibody-AT1R-Bmal1 axis promotes phenotypic transition of vascular smooth muscle cells and vascular fibrosis by XUE Lingxia, LONG Yaolin, FENG Jiayan

“…In the thoracic aorta of AT1-AA-positive rats and AT1-AA-treated VSMCs, the expression of contractile phenotype-related proteins (α-SMA, SM22) was decreased (P<0.05), while the expression of synthetic phenotype-related proteins (OPN, MMP2) was increased (P<0.05). …”
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Real-time augmented feedback for gait training: are gait responses affected by the choice of target parameter? by Mathilde Legrand, Mathilde Legrand, Mathilde Legrand, Florette Grenet, Olivia Hochstrasser, Olivia Hochstrasser, Andreas Luft, Andreas Luft, Roger Gassert, Roger Gassert, Roger Gassert, Olivier Lambercy, Olivier Lambercy, Chris Easthope Awai

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Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms by George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan

“…In eukaryotes, protein kinase signaling is regulated by a diverse array of post-translational modifications, including phosphorylation of Ser/Thr residues and oxidation of cysteine (Cys) residues. While regulation by activation segment phosphorylation of Ser/Thr residues is well understood, relatively little is known about how oxidation of cysteine residues modulate catalysis. …”
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Clinical Phenotypes and Age-Related Differences in Presentation, Treatment, and Outcome of Heart Failure with Preserved Ejection Fraction: A Vietnamese Multicenter Research by Ngoc-Thanh-Van Nguyen, Diep Tuan Tran, Pham Le An, Sy Van Hoang, Hoai-An Nguyen, Hoa Ngoc Chau

“…Prescription rate for renin-angiotensin-aldosterone system inhibitor, beta blocker, mineralocorticoid antagonist, and loop diuretic was 72.5%, 59.1%, 43.0%, and 60.6%, respectively. …”
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