Performance of a six-methylation-marker assay in predicting LEEP specimen histology results of cervical HSIL patients: a retrospective study by Ruolan Wu, Yingting Wei, Anyue Wu, Jinhua Huang, Ruiju He, Liying Gu, Zubei Hong, Lihua Qiu

“…Abstract Background Discrepancies have been found between preoperative colposcopic biopsy results and histology results of loop electrical excision procedure (LEEP) specimens. …”
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Pharmacoepidemiological analysis of routine management of heart failure patients in the Russian Federation. Part I by Yu. M. Lopatin, S. V. Nedogoda, M. V. Arkhipov, A. S. Galyavich, N. A. Koziolova, N. G. Lozhkina, E. V. Reznik, A. S. Salasyuk, M. Yu. Frolov, A. I. Chesnikova, E. V. Chumachek, L. A. Shpagina

“…The prescription rate of β-blockers and loop diuretics (mainly torasemide) increased in comparison with previous studies, while thiazide diuretics — decreased. …”
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Study on Prosthetic Hand Proprioception Feedback Based on Hybrid Vibro-Electrotactile Stimulation by Guangfei Wu, Wenqing Gu, Yi Luo, Xin Zhang, Lei Li, Jingming Hou, Haoyue Deng, Wensheng Hou, Lin Chen, Xing Wang

“…However, limited studies have examined the role of hybrid tactile feedback in closed-loop prosthetic control, particularly in relation to varying visual conditions. …”
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Gip1 GPCR regulates two sexual-stage differentiation processes in the ascomycete Fusarium graminearum by Mingyu Ding, Wanshan Wang, Yuhua Wang, Panpan Huang, Aliang Xia, Daiying Xu, Huiquan Liu, Haitao Cui, Guanghui Wang, Jin-Rong Xu, Cong Jiang

“…The C-terminal tail of Gip1 is important for intracellular signaling, while its N-terminal region and extracellular loop 3 are key for ligand recognition. …”
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CO2 utilization and sequestration potential in deep coal seams: A case study on Carboniferous coals from the Karaganda Basin, Kazakhstan by Majid Safaei-Farouji, David Misch, Reinhard F. Sachsenhofer, Nikolaos Kostoglou, Garri Gaus, Thorsten Bauersachs, Medet Junussov, Milovan Fustic

“…This study highlights how CO2 can be effectively utilized as a feedstock to enhance methane recovery while achieving long-term CO2 sequestration.…”
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Emergence and detection of gastro‐enteric virulence genes in non‐pathogenic Vibrio cholerae: Implications for public health and water safety in African developmental regions by Bright Esegbuyota Igere

“…Such results show that 53.45% (31/58) of isolates harboured more than three virulence associated genes while nanH, mshA, chxA, T6SS, T3SS, rtxA, hlyA, mshA, chxA, ace and cep fingerprints were detected predominantly with corresponding ilea‐loop test positive strains. …”
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Recovery of End-of-Life Building Materials: Thermal Decomposition and Phase Transformation of Chrysotile in Asbestos-Containing Fiber Cement Boards by António Curado, Leonel J. R. Nunes, Arlete Carvalho, João Abrantes, Eduarda Lima, Mário Tomé

“…These findings, that are part of the FiberRec project, support a systematic approach to integrating asbestos-containing waste into a closed-loop material cycle, significantly reducing carbon emissions and landfill dependency.…”
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Ensemble-Based Binding Free Energy Profiling and Network Analysis of the KRAS Interactions with DARPin Proteins Targeting Distinct Binding Sites: Revealing Molecular Determinants a... by Mohammed Alshahrani, Vedant Parikh, Brandon Foley, Gennady Verkhivker

“…The allosteric binders K13 and K19, by contrast, stabilize a KRAS-specific pocket in the α3–loop–α4 motif, introducing new hinges and bottlenecks that rewire the communication architecture of KRAS without full immobilization. …”
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Developing Immunoniosomes (INs): Antibody and Fab conjugations of niosomal nanoparticles via UV-NBS and EDC/NHS chemistry for treating glioblastoma cells by Nilufer Cakir, Hatice Oncel, Aylin Ozkan, Dilan Bicak, Sibel Akgun Bas, Nur Mustafaoglu

“…Cellular toxicity assays, conducted at a 10× dilution from commonly reported concentrations, highlighted the role of the autocrine loop in U87 glioblastoma cells. Importantly, specific Nio-Fab conjugate formulations, created through both site-specific and randomized conjugation strategies, exhibited enhanced cytotoxicity toward U87 cells while sparing healthy endothelial HUVEC cells. …”
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Two Phases of Particle Acceleration of a Solar Flare Associated with In Situ Energetic Particles by Meiqi Wang, Bin Chen, Trevor Knuth, Christina Cohen, Jeongwoo Lee, Haimin Wang, Sijie Yu

“…The first period is characterized by a single peak with a rapid rise and decay, while the second period features a more gradual HXR light curve with a harder spectrum. …”
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Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma by Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai

“…Abstract While checkpoint immunotherapy effectively mobilizes T‐cell responses against tumors, its success in hepatocellular carcinoma (HCC) is frequently undermined by immunosuppressive myeloid cells within the tumor microenvironment. …”
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Comparison of IMU-Based Knee Kinematics with and without Harness Fixation against an Optical Marker-Based System by Jana G. Weber, Ariana Ortigas-Vásquez, Adrian Sauer, Ingrid Dupraz, Michael Utz, Allan Maas, Thomas M. Grupp

“…Prior to the implementation of REFRAME, in comparison to optical estimates, skin-mounted IMU-based angles displayed mean root-mean-square errors (RMSEs) up to 6.5°, while mean RMSEs for angles based on harness-mounted IMUs peaked at 5.1°. …”
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Genome-wide identification and stress-responsive expression profiling of the TCP gene family in Cenchrus fungigraminus under drought and cold stress by Shijie Ke, Xin He, Mengmeng Zhang, Lin Luo, Yuxin Chen, Yixue Cui, Yelin Huang

“…Sequence analysis revealed that all CfuTCPs contain basic Helix-Loop-Helix conserved regions, and the majority of the CfuTCP genes were intronless. …”
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Failure and energy evolution of CFRP-confined coal samples under cyclic loading and unloading by Honglin LIU, Xiaohan GONG, Hongchao ZHAO, Haishan HUANG, Guangfeng SHI, Jiajie TIAN

“…The area and reversal amplitude of the hysteresis loops formed by their stress-strain curves were positively correlated with the number of loading-unloading cycles, while the loop density was negatively correlated with the number of cycles. ③ Both the total accumulated energy and the elastic strain energy density of the coal specimens increased with rising axial stress, exhibiting an exponential functional relationship with axial stress in magnitude. ④ As the number of CFRP layers increased from 0 to 3, the dissipation energy density shifted from a U-shaped distribution to a J-shaped distribution, and the dissipation energy rate changed from an L-shaped distribution to a V-shaped distribution. …”
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Control Libre de Modelo basado en Modos Deslizantes Integrales para Robots Submarinos Subactuados1 by R. Raygosa-Barahona, E. Olguín-Díaz, V. Parra-Vega, L.A. Muñoz-Ubando

“…Abstract: A combination of a model-free control law at the dynamic level and a guidance law at the kinematic level is proposed for the tracking of an underactuated underwater robot vehicle. The closed-loop system gives rise to chattering-free integral sliding modes for local exponential tracking of actuated coordinates, while ensuring a global stable internal dynamics under certain conditions easy to meet in practice. …”
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Disrupted Circadian Rhythms as a Novel Driver of Sarcopenia: Mechanisms, Evidence, and Future Directions by Alina Deniza Ciubean, Theodor Popa, Viorela Mihaela Ciortea, Gabriela Dogaru, Laszlo Irsay

“…It contributes significantly to frailty, reduced mobility, falls, and mortality among older adults. While multifactorial in origin, emerging research suggests a compelling link between circadian rhythm disruption and the pathogenesis of sarcopenia. …”
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Omega-3 Fatty Acids Regulate Mammary Gland Lipogenesis and Development via Gαs-Mediated cAMP–EPAC Signaling Pathway by Baofeng Li, Senlin Su, Siyu Yuan, Dongpang Chen, Qianzi Zhang, Qihui Li, Xiaoai Lin, Xiaohuan Liang, Wutai Guan, Shihai Zhang

“…Through transcriptomic analyses, the EPAC–CCCTC-binding factor (CTCF)–peroxisome proliferator-activated receptor γ (PPARγ)/CCAAT enhancer-binding protein α (C/EBPα) pathway was identified to primarily govern lipogenesis, while the EPAC–C-X-C motif chemokine ligand 14 (CXCL14)/C-X-C chemokine receptor type 4 (CXCR4) autocrine loop regulates migration of mammary epithelial cells. …”
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Morpho-Molecular and Genomic Characterization of <i>Penicillium mexicanum</i> Isolates Retrieved from a Forsaken Gold Mine by João Trovão, Fabiana Soares, Diana Sofia Paiva, António Portugal

“…Overall, this study expands the current <i>Penicillia</i> knowledge from mining environments while also enhancing our understanding regarding fungal arsenic resistance.…”
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Clinicopathologic features of superficial esophageal squamous cell carcinoma in different infiltrative growth pattern by Xing Qi, Zhenxiang Zuo, Bin Yu, Huimin Zhang, Xiujie Cui, Guangchun Li, Honglei Wu

“…Significant variables from univariate analysis were included in multivariate logistic regression to identify independent predictors of INF types.ResultsUnivariate analysis revealed that the INF of tumor was associated with tumor size, gross morphology, intraepithelial papillary capillary loop (IPCL), infiltration depth, lymphovascular invasion, and vertical positive margins (All P &lt; 0.05). …”
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Performance optimization of symmetrical multi-level boost converter using hybrid MPPT-ANN for solar energy applications by Ikram El Haji, Meriem Megrini, Mustapha Kchikach, Sanaa Sahbani, Ahmed Gaga, Abdnnebi El Hasnaoui

“…The proposed methodology is also evaluated in real time using a cost-effective implementation technique called the processor-in-the-loop technique. The Arduino Mega is employed to implement this strategy. …”
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