-
1341
The coordinated regulatory impact of AcsS and TpdA on biofilm formation in Vibrio parahaemolyticus
Published 2025-08-01“…Intracellular c-di-GMP quantification showed that AcsS elevates c-di-GMP levels, while TpdA reduces them, establishing a feedback loop. …”
Get full text
Article -
1342
Prognostic significance of overexpressed p16INK4a in patients with cervical cancer: a meta-analysis.
Published 2014-01-01“…<h4>Background</h4>p16INK4a is a tumor suppressor protein which is induced in cells upon the interaction of high-risk HPV E7 with the retinoblastoma protein by a positive feedback loop, but cannot exert its suppressing effect. Previous reports suggested that p16INK4a immunostaining allows precise identification of even small CIN or cervical cancer lesions in biopsies. …”
Get full text
Article -
1343
Mapping HIV-1 RNA structure, homodimers, long-range interactions and persistent domains by HiCapR
Published 2025-06-01“…This approach confirmed canonical structural motifs, including stem-loop architectures in the 5’-untranslated region (5’-UTR) and Rev Response Element (RRE), as well as dimerization sites within the 5’-UTR critical for viral packaging. …”
Get full text
Article -
1344
Hospital pharmacy implementation of a unit dose dispensing system: A qualitative interview study to determine experiences, views and attitudes of nursing staff
Published 2025-03-01“…The Unit-Dose-Dispensing-System (UDDS) is an essential element of the “Closed Loop Medication Management System” that enables the tracking of single medication items across the entire medication workflow thereby improving transparency, patient safety and healthcare efficiency”. …”
Get full text
Article -
1345
A Detection and Cover Integrated Waveform Design Method with Good Correlation Characteristics and Doppler Tolerance
Published 2025-05-01“…Finally, the proposed integrated waveform undergoes hardware-in-the-loop experiments, experimentally validating its performance and the effectiveness of the proposed method.…”
Get full text
Article -
1346
Artificial neural networks applied to somatosensory evoked potentials for migraine classification
Published 2025-04-01“…Migraine patients exhibit dynamic and recurrent alterations in the brainstem-thalamo-cortical loop, including reduced thalamocortical activity and abnormal habituation during the interictal phase. …”
Get full text
Article -
1347
ASAP1 Promotes Epithelial to Mesenchymal Transition by Activating the TGFβ Pathway in Papillary Thyroid Cancer
Published 2025-08-01“…ABSTRACT Background Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. While the prognosis of PTC is generally favorable, some cases exhibit aggressive behavior, leading to metastasis and recurrence. …”
Get full text
Article -
1348
A human-machine collaborative approach for high-resolution monitoring of suspended sediment dynamics in data-scarce and optically complex waters
Published 2025-08-01“…The approach follows the Human-in-the-Loop paradigm and begins by integrating limited in situ samples with expert-labeled SSC regions from Sentinel-MODIS (2017–2024) imagery to construct an initial training set, where SMOTE is applied to address class imbalance. …”
Get full text
Article -
1349
Suppression of NOX2-Derived Reactive Oxygen Species (ROS) Reduces Epithelial-to-MesEnchymal Transition Through Blocking SiO<sub>2</sub>-Regulated JNK Activation
Published 2025-04-01“…Further mechanistic analyses demonstrated that JNK signaling amplifies NOX2 expression and ROS production induced by silica exposure, while treatment with the JNK inhibitor SP600125 mitigates these effects. …”
Get full text
Article -
1350
Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse’s hand
Published 2025-05-01“…Evoked activity in S1 was biased to middle layers, consistent with thalamocortical connectivity, while that in M1 was biased to upper layers, consistent with corticocortical connectivity. …”
Get full text
Article -
1351
Design and Performance Evaluation of a <i>μ</i>-Synthesis-Based Robust Impedance Controller for Robotic Joints
Published 2025-05-01“…Furthermore, experimental results demonstrate that compared to classical impedance control, the proposed method reduces impedance rendering errors by an average of 85.71% across all tested configurations while maintaining superior passivity and interaction stability under diverse impedance conditions. …”
Get full text
Article -
1352
Cell condensation initiates organogenesis: the role of actin dynamics in supracellular self-organizing process
Published 2025-07-01“…Abstract The emergence of complex tissue architectures from homogeneous stem cell condensates persists as a central enigma in developmental biology. While biochemical signaling gradients have long dominated explanations of organ patterning, the mechanistic interplay between tissue-scale forces and thermodynamic constraints in driving symmetry breaking remains unresolved. …”
Get full text
Article -
1353
Effects of weight loss after sleeve gastrectomy on left ventricular myocardial work in obese patients
Published 2025-03-01“…This study aims to investigate the impact of weight loss after LSG on the left ventricular myocardial work (LVMW) in obese patients and explore the clinical value of the left ventricular pressure - strain loop (LV - PSL).MethodsThirty - eight obese patients (body mass index ≥ 30 kg/m2) were enrolled preoperatively, and 31 patients completed the study after six months of follow - up. …”
Get full text
Article -
1354
Case report: hyponatraemia in Wolfram syndrome
Published 2025-07-01“…She was taking regular desmopressin 100 mcg twice daily, hormone replacement therapy (HRT) and insulin degludec, and was using a closed-loop insulin pump. She had a history of recent ear infection, decreased oral intake and intermittent headache and was given antibiotic drops by her GP. …”
Get full text
Article -
1355
A novel adaptive FOCV algorithm with robust IMRAC control for sustainable and high-efficiency MPPT in standalone PV systems: experimental validation and performance assessment
Published 2024-12-01“…In the second stage, the IMRAC controller ensures accurate tracking of the MPP by adapting swiftly to changes in irradiance and temperature, while minimizing ripple and power loss. Validation of the proposed system was carried out using Processor-in-the-Loop (PIL) testing on an Arduino Due microcontroller, showcasing real-world applicability. …”
Get full text
Article -
1356
Genetic Diversity and Population Structure of Tufted Deer (<i>Elaphodus cephalophus</i>) in Chongqing, China
Published 2025-07-01“…Genetic variation was assessed using the cytochrome b (Cyt b) and D-loop regions, with analyses including F<i><sub>st</sub></i>, gene flow (<i>N</i><sub>m</sub>), neutrality tests, and Bayesian Skyline Plots (BSP). …”
Get full text
Article -
1357
Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley
Published 2023-10-01“…We confirmed host phylogeny using the D-loop sequencing method and analyzed the influence of host phylogeny and bioclimatic zone parameters on the rodent gut microbiome using high-throughput amplicon sequencing of 16S rRNA gene fragments. …”
Get full text
Article -
1358
Deep learning for sunflower (Helianthus annuus L.) mapping and stand counting: Trade-offs between closed vs. open-access methods
Published 2025-12-01“…In contrast to the models deployed within the GIS environment, while SSD produced full-field mapping, YOLOv3 exhibited scalability limitations when handling large orthomosaics. …”
Get full text
Article -
1359
Comparative Mitogenomic Analysis of Three <i>Chionea</i> Species (<i>Tipulomorpha</i>: <i>Limoniidae</i>): Insights into Phylogenetic Relationships and Selection Pressure
Published 2025-07-01“…Utilizing these 13 PCGs, we reconstructed the internal phylogenetic relationships within Tipuloidea, revealing that <i>Chionea tianhuashana</i> and <i>C. sphaerae</i> form sister branches, while (<i>C. tianhuashana</i> + <i>C. sphaerae</i>) constitutes a sister branch to <i>C. crassipes</i>. …”
Get full text
Article -
1360
High-voltage current sensing with nitrogen-vacancy centers in diamond
Published 2025-03-01“…Such a QCT can provide a robust and scalable platform for current quantum sensing technologies for high-voltage power transmission while reducing the complexity of operation and maintenance.…”
Get full text
Article