Structural and functional studies of rabbit SAMD9 reveal a distinct tRNase module that underlies the antiviral activity. by Juhi Chaturvedi, Fushun Zhang, Chen Zhang, Sonal Badhe, Yan Xiang, Junpeng Deng

“…The crystal structure of rSAMD9158-389 closely resembles hSAMD9156-385, though with difference in loop conformations. These findings demonstrate that lagomorph SAMD9 preserves core tRNA-targeting and antiviral functions despite a key residue variation and the need for an extended tRNase module.…”
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Real Time MEMS-Based Joint Friction Identification for Enhanced Dynamic Performance in Robotic Applications by Paolo Righettini, Giovanni Legnani, Filippo Cortinovis, Federico Tabaldi, Jasmine Santinelli

“…The resulting model, inclusive of the frictionless dynamics, is applied in a closed loop to improve the control performance. An experimental comparison with decentralized and non-adaptive regulators highlights severalfold reductions in tracking errors; the ability to track temperature-dependent friction variations is also shown. …”
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Event-Triggered Adaptive Neural Control for Pure Feedback Stochastic Nonlinear Systems With Input Saturation and Output State Constraints by Daogen Jiang, Longyang Wang, Jiahao Li, Jiacheng Pan

“…Theoretical analysis proves that all closed-loop signals are semi-globally uniformly ultimately bounded (SGUUB) in probability (fourth-moment sense), while the tracking error converges asymptotically to zero. …”
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Distributed Output-Feedback Tracking Control for a Class of Nonlinear Multi-Agent Systems With Polynomial Growth by Jinxiu Liu, Meiqiao Wang, Hui Wang, Wuquan Li, Fang Liu

“…To ensure that the error between the follower’s output and the leader’s output is arbitrarily small while all the states of the closed-loop system are globally bounded, a nominal system is considered first. …”
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WGAN-GP-Based Conditional GAN (cGAN) With Extreme Critic for Precipitation Downscaling in a Key Agricultural Region of the Northeastern U.S. by Jangho Lee, Sun Young Park

“…By focusing on rare high-intensity rainfall within the adversarial training loop, cGAN_ext captures crucial tail behavior that can be overlooked by conventional approaches. …”
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A Framework for Constructing Large-Scale Dynamic Datasets for Water Conservancy Image Recognition Using Multi-Role Collaboration and Intelligent Annotation by Xueying Song, Xiaofeng Wang, Ganggang Zuo, Jiancang Xie

“…The framework introduces two new roles, data augmentation specialists and automatic annotation operators, to establish a closed-loop process that includes dynamic classification adjustment, data augmentation, and intelligent annotation. …”
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Adaptive integral sliding mode MPPT control for wind turbines with fixed‐time convergence by Qi Chen, Lin Wang, Yong Sun, Shuzong Xie, Ruiliang Wang

“…The objective is to optimize wind power generation by maximizing energy capture efficiency while addressing challenges associated with behind‐the‐meter renewables, load flexibility, and encouraging prosumers' participation. …”
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De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS by Wenfeng Zhao, Guofeng Chen, Jian He, Xiaofang Shen, Muya Xiong, Liwei Xiong, Zhihao Qi, Hang Xie, Wanchen Li, Jiameng Li, Huixia Dou, Hangchen Hu, Haixia Su, Qiang Shao, Minjun Li, Hongbin Sun, Yechun Xu

“…Here we report the structural, biochemical, cellular, and mechanistic characterization of the XL series of allosteric inhibitors, designed to engage an innovative allosteric site near the activation loop of cGAS. Among them, XL-3156 and XL-3158 emerge as potent, selective, cross-species cGAS inhibitors that simultaneously occupy allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation and thereby attenuating the cGAS-DNA interactions. …”
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Functional validation of somatic variability in TP53 and KRAS for prediction of platinum sensitivity and prognosis in epithelial ovarian carcinoma patients by Al Obeed Allah Mohammad, Ali Esraa, Krus Ivona, Holý Petr, Haničinec Vojtěch, Ambrozkiewicz Filip, Rob Lukáš, Hruda Martin, Mrhalová Marcela, Kopečková Kateřina, Bartáková Alena, Bouda Jiří, Spálenková Alžběta, Souček Pavel, Václavíková Radka

“…Carriers of TP53 variants disrupting the DNA binding loop had significantly longer platinum-free intervals than the rest (p = .037). …”
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Direct high-precision radon quantification for interpreting high-frequency greenhouse gas measurements by D. Kikaj, E. Chung, A. D. Griffiths, S. D. Chambers, G. Forster, G. Forster, A. Wenger, P. Pickers, P. Pickers, C. Rennick, S. O'Doherty, J. Pitt, K. Stanley, D. Young, L. S. Fleming, L. S. Fleming, K. Adcock, E. Safi, T. Arnold, T. Arnold

“…Furthermore, we assign uncertainties for each reported 30 min radon estimate (assuming these steps have been followed) and validate the final result through comparison of diurnal and sub-diurnal radon characteristics with co-located GHG measurements. While derived for a network of UK observatories, the proposed standardized protocol could be equally applied to two-filter dual-flow-loop radon observations across larger networks, such as the Integrated Carbon Observation System (ICOS) or the Global Atmosphere Watch (GAW) baseline network.…”
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Extraction and Energy Management of Solar Photovoltaic, Fuel Cell, and Battery Systems Using a Novel Multi Port Power Converter for DC Microgrid Applications by Guguloth Nagesh, M. Venkatesh Naik, Dogga Raveendhra, Praveen Kumar Bonthagorla

“…To achieve this, a closed-loop control strategy, along with the EMS, is implemented. …”
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A New Two-Port MIMO Filtenna With Tunable Bandwidth and Center Frequency by Alper Turkeli, Ali Kursad Gorur, Yasemin Altuncu, Adnan Gorur

“…Thus, the bandwidth can be tuned by the singly biased varactor diode, while the center frequency is tuned by controlling all varactors. …”
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Tuberculosis and diabetes mellitus: a narrative review on the growing syndemic in low- and middle-income countries by Ibrahim Khalil, Md. Imran Hossain

“…It examines the bidirectional relationship where DM (hyperglycemia) impairs immunity (macrophages/neutrophils), while TB-induced inflammation (TNF-α, IL-6) leads to insulin resistance and worsened glycemic control, creating a feedback loop that complicates patient outcomes. …”
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Insights into phylogenetic positions and distribution patterns: Complete mitogenomes of two sympatric Asian horned toads in Boulenophrys (Anura: Megophryidae) by Hongmei Xiang, Qiang Zhou, Wei Li, Juan Shu, Zhirong Gu, Wansheng Jiang

“…The mitogenome of B. sangzhiensis was 16,950 bp, while that of B. tuberogranulata was 16,841 bp, each comprising 13 protein‐coding genes (PCGs), 22 transfer RNA genes (tRNAs), two ribosomal RNA genes (rRNAs), and a noncoding control region (D‐loop). …”
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Steering-Angle Prediction and Controller Design Based on Improved YOLOv5 for Steering-by-Wire System by Cunliang Ye, Yunlong Wang, Yongfu Wang, Yan Liu

“…The YOLOv5Ms model achieves a 30.34% reduction in weight storage space while simultaneously improving accuracy by 7.38% compared to the YOLOv5s model. …”
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Learning efficient haptic shape exploration with a rigid tactile sensor array. by Sascha Fleer, Alexandra Moringen, Roberta L Klatzky, Helge Ritter

“…The proposed algorithm simultaneously optimizes main perception-action loop components: feature extraction, integration of features over time, and the control strategy, while continuously acquiring data online. …”
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Navigating Vancomycin and Acute Kidney Injury: AUC- vs. Trough-Guided Monitoring in Initial and Steady-State Therapy by Astrid Marovič, Tomaž Vovk, Maja Petre

“…One cohort was managed using trough-guided monitoring (<i>n</i> = 85), while the other was monitored using the AUC-guided approach (<i>n</i> = 139). …”
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Efficient recycling of anhydride-cured epoxy resins for electrical insulation: Green economy and tunable performance by Hechen Liu, Ying Zou, Jinyang Xu, Songsong Zhou, Xiong Wu, Yunpeng Liu

“…Central to this work is a uniquely designed benzyl alcohol/K3PO4 recycling system, which enables the closed-loop utilization of not only the epoxy resin but also the system itself, owing to the facile separation of its components. …”
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A Transformerless Bidirectional Active Switched Inductor-Based SEPIC High-Gain DC&#x2013;DC Converter With Buck&#x2013;Boost Capability by Sunil Mandal, Prajof Prabhakaran, D. Arun Dominic, Arun P. Parameswaran

“…Furthermore, detailed small-signal modeling and closed-loop controller design are developed for both voltage-mode and current-mode control. …”
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Tuning the Resistance of a VO2 Junction by Focused Laser Beam and Atomic Force Microscopy by Zhuoqun Fang, Melissa Alzate‐Banguero, Amit R. Rajapurohita, Forrest Simmons, Erica W. Carlson, Zhuoying Chen, Lionel Aigouy, Alexandre Zimmers

“…These patterns persist while the base temperature is held constant within the hysteretic region while being easily removed totally by simply lowering the base temperature. …”
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