Vision-Ray-Calibration-Based Monocular Deflectometry by Poses Estimation from Reflections by Cheng Liu, Jianhua Liu, Yanming Xing, Xiaohui Ao, Wang Zhang, Chunguang Yang

“…The integrated calibration amalgamates the cost functions from the separate calibrations with the intersection of lines in Plücker space. …”
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Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia by Jacqueline E. Taudien, Diana Bracht, Heike Olbrich, Sebastian Swirski, Fulvio D’Abrusco, Bert Van der Zwaag, Maike Möller, Thomas Lücke, Norbert Teig, Ulrika Lindberg, Kai Wohlgemuth, Julia Wallmeier, Anja Blanque, Christos Gatsogiannis, Sebastian George, Christoph Jüschke, Marta Owczarek-Lipska, Dorothee Veer, Hester Y. Kroes, Enza Maria Valente, G. Christoph Korenke, Heymut Omran, John Neidhardt

“…In two unrelated families, a deep-intronic variant (KIAA0586/TALPID3:c.3990 + 3186G>A) activated a cryptic exon. We performed histological and functional analyses in native and air-liquid interface (ALI) cultured respiratory cells. …”
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Glypican 3 as target therapy to prevent cell migration and proliferation in rhabdomyosarcoma by Maira Bacchiega, Stefania D’Agostino, Antonella Grigoletto, Elena Poli, Paolo Bonvini, Gianni Bisogno, Gianfranco Pasut, Michela Pozzobon

“…Functional assays were performed with the antineoplastic drug doxurubicin and the WNT3a inhibitor, ipafricept. …”
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Methylation-induced suppression of BEX1 activates AKT/ERK/STAT3 signaling pathways regulating cell cycle and apoptosis in glioma by Li-Zhi Xiao, Shi Feng, Zhen He, Rui Mao, Kai Qian, Zhi-Ying Zhou, Huabao Cai, Mengyu Zhao, Cunzhi Wang, Tianhang Yu, Zi-Yu Zhao, Jie Li

“…We conducted bioinformatics analyses to assess BEX1 expression differences in glioma using tissue samples, followed by validation through Western blot and qRT-PCR. Functional assays in glioma cell lines were performed, employing gene transfection and small molecule inhibitors to further explore BEX1’s role in the AKT/ERK/STAT3 signaling pathways. …”
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Allelic Variation at the Rht8 Locus in a 19th Century Wheat Collection by Linnéa Asplund, Matti W. Leino, Jenny Hagenblad

“…The use of WMS261 and other functional markers for analyses of historical specimens and characterization of historic crop traits is discussed.…”
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Annexin A3 Knockdown Suppresses Lung Adenocarcinoma by Ying-Fu Liu, Qing-Qing Liu, Yue-Hua Zhang, Jing-Hua Qiu

“…However, the biological functions of Anxa3 in LADC are not fully clear. In this study, in vitro and in vivo assays were performed to investigate the effects of Anxa3 downregulation on the growth, migration, invasion, metastasis, and signaling pathway activation of LADC cells. …”
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TNF-α-Induced NF-κB Alter the Methylation Status of Some Stemness Genes in HT-29 Human Colon Cancer Cell by Hamid Zand, Seyed Ahmad Hosseini, Makan Cheraghpour, Meysam Alipour, Fatemeh Sedaghat

“…Materials and Methods: This experimental study was performed on HT-29 cells as human colorectal cancer cell lines. …”
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Indisulam synergizes with melphalan to inhibit Multiple Myeloma malignancy via targeting TOP2A. by Chengyu Wu, Chao Wu, Jia Liu, Mingyuan Jia, Xinyi Zeng, Ze Fu, Ziqi He, Wenbin Xu, Hua Yan

“…We predicted the synergistic effect of the combination treatment based on calculations performed on a website, and further explored the effect of indisulam in combination with melphalan on MM cell lines and xenografts. …”
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Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation. by Paola Rossolillo, Flore Winter, Etienne Simon-Loriere, Sarah Gallois-Montbrun, Matteo Negroni

“…In evolution strategies aimed at isolating molecules with new functions, screening for the desired phenotype is generally performed in vitro or in bacteria. …”
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Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells. by A Solís-López, U Kriebs, A Marx, S Mannebach, W B Liedtke, M J Caterina, M Freichel, V V Tsvilovskyy

“…For determination of the functional role of the expressed TRPV channels we performed measurements of intracellular free Ca2+ concentrations and beta-hexosaminidase release in PMCs obtained from wild type and mice deficient for corresponding TRPV1, TRPV2 and TRPV4 in response to various receptor-mediated and physical stimuli. …”
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Akt o wspieraniu produkcji amunicji (ASAP) a rozwój zdolności obronnych Unii Europejskiej w kontekście wojny w Ukrainie by Adriana Kalicka-Mikołajczyk

“…In such a scenario, defence companies often faced the need to reduce production rates in order to keep production lines afloat and maintain skilled personnel, while producing limited quantity of defence systems for national customers. …”
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Quantitative evaluation of DNA damage repair dynamics to elucidate predictors of autism vs. cancer in individuals with germline PTEN variants. by Ruipeng Wei, Masahiro Hitomi, Tammy Sadler, Lamis Yehia, Daniela Calvetti, Jacob Scott, Charis Eng

“…The pleiotropy of the syndrome may, in part, be due to the alterations of the key multi-functions of PTEN. Maintenance of genome integrity is one of the key biological functions of PTEN, but no integrative studies have been conducted to quantify the DNA damage response (DDR) in individuals with PHTS and to relate to phenotypes and genotypes. …”
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Integration of single-cell and bulk RNA sequencing to identify a distinct tumor stem cells and construct a novel prognostic signature for evaluating prognosis and immunotherapy in... by Fengyun Zhao, Mengting Chen, Tianjiao Wu, Mingfang Ji, Fugui Li

“…Immune infiltration was evaluated using the Cibersortx algorithm, and drug response prediction was performed using the pRRophetic package. TAF10 functional investigations in LUAD cells involved bioinformatics analysis, qRT-PCR, Western blot, immunohistochemistry, and assays for cell proliferation. …”
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SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilization by Feng Xu, Chen-Cheng Zhu, Chen Lu, Guang-Yao Ning, Ren-Quan Zhang

“…Immune-related and functional analyses were performed using TIMER, TISIDB, TISCH, Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA). …”
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circRNA circ_102049 Implicates in Pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p by Jie Zhu, Yong Zhou, Shanshan Zhu, Fei Li, Jiajia Xu, Liming Zhang, Hairong Shu

“…In vitro and in vivo experiments were performed to evaluate the functions of circRNA_102049. …”
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Femtolaser refractive autokeratoplastic: first results and prospects by H. V. Sitnik, A. Yu. Slonimsky, Yu. B. Slonimsky

“…Between 3 to 6 months after surgery, we observed the increasing of visual functions (like UCVA and BCVA). The improvement of BCVA was observed in 94.1 %, and in 76.5 % of cases the increase was more than 3 lines. …”
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CCT8 drives colorectal cancer progression via the RPL4-MDM2-p53 axis and immune modulation by Yangyang Teng, Hao Lin, Zijian Lin, Xichen Li, Yejiao Ruan, Binhui Pan, Jinlin Ge, Yuesheng Zhu, Daopo Lin, Qingji Ying, Zhenzhai Cai, Xuanping Xia

“…Functional assays, including CCK-8, transwell, wound-healing, and flow cytometry, were conducted using DLD-1 and HCT116 cell lines to assess the effects of CCT8 on cell proliferation, migration, invasion, and apoptosis. …”
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Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells by Zhenhua Jiang, Yongfeng Wang, Chi Zhang, Shuangyin Han

“…It was highly expressed in GCY tissues and GC cell lines. Further analysis using The Cancer Genome Atlas database confirmed its oncogenic effects. …”
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Integrated analysis and experimental validation reveal the prognostic and immunological features associated with coagulation in hepatocellular carcinoma by Guangzhen Qu, Kun Liu, Weiyu Xu, Dongming Li

“…The qPCR confirmed the upregulation of GPD2 expression in HCC tumor cell lines, compared to normal liver cell lines. Immunohistochemical staining confirmed the high expression of GPD2 in HCC tumor tissues compared to normal tissues. …”
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Scutellarin suppresses ovarian cancer progression by targeting METTL5 by Ling Ding, Cenxin Luo, Nathaniel Weygant, Wutao Chen, Dan Ru, Yi Lai, You Wang, He Li

“…The effects of Scutellarin on cell proliferation and migration were assessed in ovarian cancer cell lines including SKOV3, A2780, OVCAR3, and OVCAR8. …”
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