Differences in Surgical Management of Corneal Perforations, Measured over Six Years by Katarzyna Krysik, Dariusz Dobrowolski, Anita Lyssek-Boron, Judyta Jankowska-Szmul, Edward A. Wylegala

“…To report the surgical approach, anatomical and functional results, and complications in the group of patients with corneal perforation. …”
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Cuproptosis-related lncRNA predicts prognosis and immune pathways in osteosarcoma patients by LIAO Jun, FENG Yanbin, XI Deshuang, ZONG Shaohui

“…Single-sample gene set enrichment analysis (ssGSEA) was utilized to explore the relationship between CRLs model scores and signaling pathways in OS. Functional and pathway enrichment analyses were performed by Gene Ontology (GO) and Kyoto Encyclopedia of Genomes (KEGG) in OS patients of different risk groups. …”
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Impact of Poly(Lactic Acid) and Graphene Oxide Nanocomposite on Cellular Viability and Proliferation by Karina Torres Pomini, Júlia Carolina Ferreira, Laira Mireli Dias da Silva, Paulo Gabriel Friedrich Totti, Monique Gonçalves Alves, Eliana de Souza Bastos Mazuqueli Pereira, Marcelo Melo Soares, Durvanei Augusto Maria, Rose Eli Grassi Rici

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Transcriptome analysis of H2O2-treated wheat seedlings reveals a H2O2-responsive fatty acid desaturase gene participating in powdery mildew resistance. by Aili Li, Rongzhi Zhang, Lei Pan, Lichuan Tang, Guangyao Zhao, Mingzhu Zhu, Jinfang Chu, Xiaohong Sun, Bo Wei, Xiangqi Zhang, Jizeng Jia, Long Mao

“…To investigate the cellular and metabolic responses triggered by H(2)O(2), we performed an mRNA tag analysis of wheat seedlings under 10 mM H(2)O(2) treatment for 6 hour in one powdery mildew (PM) resistant (PmA) and two susceptible (Cha and Han) lines. …”
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Antioxidant Bio-Compounds from Chestnut Waste: A Value-Adding and Food Sustainability Strategy by Roberta Barletta, Alfonso Trezza, Andrea Bernini, Lia Millucci, Michela Geminiani, Annalisa Santucci

“…In vitro assays evaluated the phenolic and flavonoid content, as well as the antioxidant activity of the three extracts, confirming the cultivar <i>Cecio</i> as the richest in these bioactive compounds and the most performative in antioxidant assays. In vitro antioxidant and oxidative stress recovery assays on SaOS-2, fibroblast, and chondrocyte cell lines displayed a strong antioxidant activity. …”
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LINC01871 facilitates cervical cancer cell migration and immune escape by targeting miR‐873‐3p/MAP3K2 axis by Yan Li, Li Wei, Hui‐Hui Zhang, Hong‐Fei Ci, Duo‐Jie Li

“…In this study, we examined the expression levels and subcellular localization of LINC01871 in CC cell lines. Functional assays, including transwell migration and invasion assays as well as macrophage phagocytosis assays, were conducted to estimate CC cell invasiveness, migration, and immune response. …”
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Silencing of bach1 gene by small interfering RNA–mediation regulates invasive and expression level of miR-203, miR-145, matrix metalloproteinase-9, and CXCR4 receptor in MDA-MB-468... by Reza Mohammadzadeh, Mojgan Saeid Harouyan, Seyed Mansour Ale Taha

“…The aim of this study was to investigate the effect of specific bach1 small interfering RNAs, on the invasive and expression level of miR-203, miR-145, matrix metalloproteinase-9, and CXCR4 receptor which play a role in cancer metastasis, in MDA-MB-468 cell lines. Methods: Small interfering RNA transfection was performed with transfection regent. …”
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Long non-coding RNA SNHG16 promotes tumor progression and cisplatin resistance in esophageal squamous cell carcinoma via miR-497-5p/HK2 axis by Xiaofeng Zhu, Minghua Xie, Yayun Cui

“…Methods RT-qPCR and western blotting were utilized to detect SNHG16, miR-497-5p, and HK2 expression in DDP-resistant/sensitive ESCC tissues and cells. In vitro functional experiments were performed by transfecting DDP-resistant ESCC cells lines with sh-SNHG16, including CCK8, flow cytometry, EdU assay, and transwell assay. …”
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FAK inhibition disrupts tumor growth, apoptosis, and transcriptional regulation in GI-NETs by Lara Toffoli, Angeliki Ditsiou, Luca Triboli, Victorine Hamm, Eva Moschioni, Francesca D’Este, Teresa Gagliano

“…Methods: Human GI-NET cell lines (GOT1 and COLO320DM) were treated with Y15, a kinase inhibitor, and PROTAC-FAK (BI-0319), a degrader that abrogates both enzymatic and scaffold functions. siRNA-mediated knockdown of FAK was employed for functional validation. …”
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Response gene to complement 32 promotes tumorigenesis by mediating DNA damage repair and inhibits CD8+ T cells infiltration in diffuse large B-cell lymphoma by Xiyuan Zhang, Xiyuan Zhang, Tiange Lu, Chunlei Shi, Mengfei Ding, Ling Wang, Xinting Hu, Xin Wang, Xin Wang

“…To evaluate the role of RGC32 in DLBCL, lentivirus vectors either encoding shRGC32 or shControl were transfected into DLBCL cell lines. RNA-sequencing (RNA-seq) analysis was performed between shRGC32 and shControl stably transfected OCI-LY1 cells and functional enrichment analyses used gene ontology (GO) and kyoto encyclopedia of genes and genomes (KEGG). …”
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Adaptive system for visualization of the electromagnetic scattering field of aircraft by Z. M. Kurbanismailov, A. T. Tarlanov, E. D. Matyash, E. S. Karbova

“…Hence, the relevance of ensuring the EMC of integrated technical systems that perform the functions  of  measurement, data processing and the formation of control actions, both digital and analog, is obvious. …”
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Global miRNA Expression Profiling Identifies miR-1290 as Novel Potential oncomiR in Laryngeal Carcinoma. by Joanna Janiszewska, Marcin Szaumkessel, Magdalena Kostrzewska-Poczekaj, Kinga Bednarek, Julia Paczkowska, Joanna Jackowska, Reidar Grenman, Krzysztof Szyfter, Malgorzata Wierzbicka, Maciej Giefing, Malgorzata Jarmuz-Szymczak

“…With the aim of better understanding its genetic background we performed global miRNA expression profiling of LSCC cell lines and primary specimens. …”
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The Structure of Information Support System of the Enterprise Production Work by A. M. Bochkarev

“…In comparison with the academic approach describing information support as a totality of system elements it was shown that the interaction of elements' totality aims at performing key functions of information support (collection, processing, storage, revision, renewal of information, preparation for use) and attaining the principle goal of timely delivery of objective, trustworthy, complete information about the condition of enterprise production work and its external environment. …”
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Adult Neural Stem Cells: Basic Research and Production Strategies for Neurorestorative Therapy by E. M. Samoilova, V. A. Kalsin, N. M. Kushnir, D. A. Chistyakov, A. V. Troitskiy, V. P. Baklaushev

“…Over many decades, constructing genetically and phenotypically stable lines of neural stem cells (NSC) for clinical purposes with the aim of restoring irreversibly lost functions of nervous tissue has been one of the major goals for multiple research groups. …”
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Large-scale predictions of alternative protein conformations by AlphaFold2-based sequence association by Myeongsang Lee, Joseph W. Schafer, Jeshuwin Prabakaran, Devlina Chakravarty, Madeleine F. Clore, Lauren L. Porter

“…These methods often assume that AF2 relies on evolutionary couplings to predict alternative protein conformations, but they perform poorly on fold-switching proteins, which remodel their secondary structures and modulate their functions in response to cellular stimuli. …”
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MCTP2 is a novel biomarker promoting tumor progression and nodal metastasis in oral squamous cell carcinoma by Yudai Shimojukkoku, Ayami Tomishima, Takayuki Ishida, Yuka Kajiya, Yasunobu Oku, Koshiro Kawaguchi, Takahiro Tsuchiyama, Kaori Shima, Hideto Saijo, Tomonori Sasahira

“…MCTP1 has been reported to exhibit tumor-promoting activity in several cancer types; however, the role of MCTP2 in cancer remains largely unknown. In this study, we performed a comprehensive analysis using big data from over 500 head and neck cancer cases registered in The Cancer Genome Atlas (TCGA), expression profiling of 63 OSCC samples, and in vitro functional assessment using cell lines to elucidate MCTP2 involvement in OSCC. …”
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Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia by Tianping Chen, Nan Wei, Wenxiu Lv, Lijun Qu, Qian Qu, Chaohong Wu, Yuan Ling, Haipeng Liu, Hongjun Liu

“…AML cell lines (Kasumi-1, U937, etc.) were treated with Elesclomol-CuCl2 to induce cuproptosis. …”
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Synthesis of a novel mitochondrial fluorescent probe - killing cancer cells in vitro and in vivo by Xiaowen Yang, Yiting Zhan, Yifei Li, Yifei Li, Xinzhuang Shen, Xinzhuang Shen, Yuqiu Ma, Zongjun Liu, Zongjun Liu, Yipeng Liu, Chengjin Liang, Xiaoyuan Zhang, Yehao Yan, Wenzhi Shen

“…Specifically, MPM-1 significantly reduced the proliferation and migration of lung cancer cell lines A549 and H1299, as well as colon cancer cell lines SW480 and LOVO, with IC50 values of 4.900, 7.376, 8.677, and 7.720 µM, respectively, while also promoting apoptosis. …”
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Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p by Qi Liu, Qi Liu, Qi Liu, Yong-Kui Yu, Yong-Kui Yu, Hao-Miao Li, Hao-Miao Li, Wei Wang, Wei Wang, Jing Xu

“…Rescue experiments and Western blot analyses were performed to identify downstream targets and elucidate the underlying regulatory mechanisms.ResultsAmong the five upregulated circRNAs identified, only hsa_circ_0018909 consistently showed high expression in NSCLC tissues and cell lines and was associated with shorter overall and disease-free survival. …”
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SCIENTIFIC APPROACH TO A COMPLEX ASSESSMENT OF DETERMINANTS OF THE INSURANCE MARKET DEVELOPMENT OF UKRAINE by L. V. Popova, N. O. Kovalchuk, D. D. Polagnyn

“…An estimation of the influence of each of the selected factors is carried out and based on the conducted factor analysis, a significant impact on their volume of indicators of the number of insurance companies, GDP per capita and exchange rate, is performed. Alongside with this, trend lines are constructed and forecast values of gross insurance premiums and payments are determined. …”
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