Candidate gene identification and marker development for seed coat peeling rate in peanut (Arachis Hypogaea L.) by Hongfei Liu, Ziqi Sun, Feiyan Qi, Xiao Wang, Meng Zhang, Juan Wang, Xiaobo Wang, Ziqiang Mo, Mingbo Zhao, Chenyang Zhi, Mengmeng Wang, Zhiyuan Zhou, Linhong Xu, Wenzhao Dong, Zheng Zheng, Xinyou Zhang

“…A genome-wide association study (GWAS) was conducted on a natural population comprising 353 peanut accessions, while quantitative trait locus (QTL) mapping was performed using a recombinant inbred line (RIL) population of 521 lines derived from YZ9102 and WT09-0023. …”
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Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects by Dongqi You, Lining Lin, Minyi Dong, Yunhong Wu, Yijie Hu, Xinyue Hu, Yangjie Shao, Yuan Xie, Menghan Xu, Guancong Chen, Rong Lan, Haiying Ma, Yunting Zhou, Huiming Wang, Binjie Jin, Mengfei Yu

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Single-cell transcriptomics and machine learning unveil ferroptosis features in tumor-associated macrophages: Prognostic model and therapeutic strategies for lung adenocarcinoma by Ting Ji, Ting Ji, Juanli Jiang, Juanli Jiang, Xin Wang, Xin Wang, Kai Yang, Kai Yang, Shaojin Wang, Shaojin Wang, Bin Pan, Bin Pan

“…The risk model (Risk Score = HLF × (−0.153) + HPCAL1 × 0.261 + NUPR1 × (−0.21)) demonstrated robust predictive performance in both the TCGA and GSE13213 cohorts, with 1-, 3-, and 5-year AUC values of 0.756, 0.753, and 0.705. …”
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Characterization of novel anoikis-related genes as prognostic biomarkers and key determinants of the immune microenvironment in esophageal cancer by Yani Su, Ming Zhang, Peng Xu, Pengfei Wen, Ke Xu, Jiale Xie, Xianjie Wan, Lin Liu, Zhi Yang, Mingyi Yang

“…A total of 794 ARGs were curated from GeneCards database. Functional enrichment analyses of EC-related differentially expressed ARGs were performed using Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Design of Tri-frequency Combiner Based on Inverted T-stub Combiner Network by LIU Zirui, WANG Haoyu, HUANG Kama

“…Combined with the impedance transformation of λ/4 transmission lines, this design achieves an equivalent open-circuit state at the corresponding combiner ports. …”
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Upregulation of circGDI2 inhibits tumorigenesis by stabilizing the expression of RNA m6A demethylase FTO in oral squamous cell carcinoma by Yuwei Gu, Ling Sheng, Xiaoxiao Wei, Yuling Chen, Yuntao Lin, Zhangfu Li, Xiaolian Li, Huijun Yang, Yufan Wang, Hongyu Yang, Yuehong Shen

“…Animal experiments were performed to verify the results in vivo. Results: The expression of circGDI2 was markedly decreased in both OSCC cell lines and patient tissues. …”
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RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response by Teng-Feng Li, Paul Rothhaar, Arthur Lang, Oliver Grünvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Gonçalves Magalhães, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Viet Loan Dao Thi, Stephan Urban, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Ralf Bartenschlager, Ralf Bartenschlager, Andreas Pichlmair, Andreas Pichlmair, Volker Lohmann, Volker Lohmann

“…We aimed to identify the factors contributing to the TLR3 response in hepatocytes via CRISPR/Cas9 screening.MethodsA genome-wide CRISPR/Cas9 screen on the TLR3 pathway was performed in two liver-derived cell lines, followed by siRNA knockdown validation. …”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…The nomogram of combined ISS, age, and risk score showed good predictive performance. qRT-PCR of cell lines and clinical specimens provided further support for prognostic modeling.ConclusionOur research reveals the prognostic value of disulfidptosis in MM and provides new perspectives for identifying heterogeneity and therapeutic targets.…”
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Ganhar a vida" a partir do jornalismo e da cultura by Mariana Reis, Isaltina Gomes

“…We also observed that professional journalists have to keep up with changes to the world of work, and strike a balance between developing new skills and performing new functions, thus adapting to the demands and possibilities of present day work. …”
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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. Results were imported to Covidence. …”
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The Female Athlete Triad: A Metabolic Phenomenon by Anne B. Loucks

“…Energy availability is the amount of dietary energy remaining after exercise training for all other physiological functions each day.  The specific kind of reproductive dysfunctions caused by low energy availability are functional hypothalamic menstrual disorders.  …”
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Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway by Wenjing Zhou, Jiwei Wang, Qichao Qi, Zichao Feng, Bin Huang, Anjing Chen, Di Zhang, Wenjie Li, Qing Zhang, Rolf Bjerkvig, Xingang Li, Jian Wang

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Quantitative analysis of the effect of microtubule-targeting drugs on the microtubule cytoskeleton of breast cancer cells with different invasive properties by Michallet, Sophie, Bosc, Lauriane, Lafanechère, Laurence

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Enhancing the sustainability of rabbit production from the perspective of animal genetics by Juan Pablo Sánchez

“…The major challenge when considering social and environmental sustainability plans in breeding programmes is how to properly include these dimensions in the functions defining the relevance of the different traits to be considered during the development of specialised lines. …”
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Ring-finger protein RNF126 promotes prostate cancer progression via regulation of MBNL1 by Xin Jiang, Ji Li, Jiali Zhang, Yulei Zhao, Guoqin He, Xiaohui Yao

“…However, although some functions of RNF126 in prostate cancer (PCa) cell lines has been reported, more biological functions and in-depth mechanisms should be further clarified in PCa. …”
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[18F]PARPi Imaging Is Not Affected by HPV Status In Vitro by Navjot Guru, Paula Demétrio De Souza França, Giacomo Pirovano, Cien Huang, Snehal G. Patel, Thomas Reiner

“…Effects of external beam ionizing radiation were investigated in vitro, and survival was investigated via colony-formation assay. [18F]PARPi uptake experiments were performed on HPV-negative and HPV-positive cell lines to quantify PARP1 expression. …”
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Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting by Chang Liu

“…The expression validation, prognostic significance, and mutational analysis of CDCA genes were performed using various databases. Functional assays, including gene knockdown, colony formation, proliferation, and wound healing, were conducted in U87MG cells to assess the role of CDCA7 and CDCA8 in GBM. …”
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TOMM40L promotes proliferation and migration of triple negative breast cancer cells and correlates with poor prognosis by ZHANG Ke, LU Jiangning, SUN Lixin, YU Long, SUN Lichao, RAN Yuliang

“…TOMM40L levels were enhanced in TNBC cell lines as compared to other non-TNBC cell lines. CCK-8 and Transwell assay demonstrated that TOMM40L knockdown reduced the proliferation and migration of TNBCcell lines. …”
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Protein arginine N-methyltransferase 1 promotes the proliferation and metastasis of hepatocellular carcinoma cells by Qing Gou, ShuJiao He, ZeJian Zhou

“…We investigated the clinical and functional significance of protein arginine N-methyltransferase 1 in a series of clinical hepatocellular carcinoma samples and a panel of hepatocellular carcinoma cell lines. …”
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Interferon-induced factor 16 is essential in metastatic melanoma to maintain STING levels and the immune responses upon IFN-γ response pathway activation by Yoshinori Hayashi, Yuta Kobayashi, Qiang Yu, Dave Hoon, Matias A Bustos

“…Functional assays combined with cytokine arrays were performed using MM cell lines to validate in silico data. …”
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