Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma by Lizhi Zhou, Hengcheng Lu, Bin Fu, Jianhan Fu

“…Using Cox regression and machine learning, our model achieved a 5-year area under curve (AUC) of 0.79, surpassing existing models in predictive performance. Enrichment analysis revealed distinct immune and metabolic landscapes between ARGs high- and low-risk groups. …”
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Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…In vitro cytotoxicity of hybrid peptides in human cervical cancer cells lines HeLa and Ca Ski was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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Animal welfare parameters. A quality indicator of sheep slaughter in a province of Ecuador by Rafael Alfonso Garzón-Jarrín, Jorge Enrique Arellano-Yasaca, Lucia Monserrath Silva-Déley, Luis Alonso Chicaiza-Sánchez, Nancy Margoth Cueva Salazar

“…With reference to the evaluation of the personnel, 44 % indicated that there are trained personnel for the performance of their functions. It is concluded that the stress caused by deficient AW employment negatively affects the quality of the meat of the sheep slaughtered due to poor pre-mortem handling in the municipal slaughterhouse of Guamote, so it would be a priority to establish lines of work for the welfare of sheep destined for human consumption in the stages before, during and after slaughter, this will avoid the consequences of a poor process from transportation, housing, health, behavior, equipment management and exsanguination.…”
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o8G-modified circKIAA1797 promotes lung cancer development by inhibiting cuproptosis by Haotian Xu, Qingyun Zhao, Dunyu Cai, Xingcai Chen, Xiaodong Zhou, Yihong Gao, Jiaxi Wu, Shengyi Yuan, Deqing Li, Ruirui Zhang, Wenyi Peng, Gang Li, Aruo Nan

“…Methods circRNA differential expression profiles in lung cancer were revealed via RNA high-throughput sequencing, and circKIAA1797 expression in lung cancer cell lines and tissues was detected using qPCR. Experiments such as o8G RNA immunoprecipitation (o8G RIP) and crosslinking immunoprecipitation (CLIP) were performed to explore the presence of o8G on circKIAA1797. …”
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Hydrothermal vents as observatories for future ocean acidification (OA) scenarios: an in-situ study to unravel the involvement of ATP binding cassette transporters in the adaptatio... by Silvia Simonetti, Silvia Simonetti, Kevin Nzumbi Mutemi, Patrizia Romano, Patrizia Romano, Till Luckenbach, Valerio Zupo, Maria Cristina Gambi, Ilaria Corsi

“…There is growing evidence for their involvement to mediate tolerance towards acid-stress in bacteria and tumor cell lines. Such a function may be relevant for the ability of marine species to cope with OA and may be important to consider when predicting future OA scenarios for marine fauna. …”
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Mechanism study of KCMF1 promoting proliferation and NF-κB signaling transduction in colorectal cancer cells by WU Zhibai, XU Guiqin, ZHANG Li, YANG Zhaojuan, LIU Yun, JIAO Kun, CHEN Zehong, XU Chen, ZUO You, ZHENG Ningqian, YE Zhiqian, LIU Yongzhong

“…Furthermore, immunohistochemical staining was performed to detect the protein level of KCMF1 in 90 paired human CRC tissues and adjacent non-tumor tissues. …”
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Analysis of the Influence of Comorbid States on COVID-19 Severity and In-Hospital Mortality for Further Application in an Outpatient Setting by A. Kurakh, I. Chopey, K. Hechko

“…Primary care physicians were on the front-lines, handling outpatient care, performing triage, consulting patients on potential risks, symptoms of concern and treatments options. …”
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Developing Heterogeneous Porous 3D-Printed SiO₂-Pd-K₂SiO₃ Monolithic Catalyst via Surface MOF Growth and Pyrolysis for the Synthesis of Antitumoral... by Alexandrina Druta, Rania Bouhmala, Teqwa Ragdi, Mariangel Luna, Manuel Bañobre-López, Christian F. Masaguer, Manuel Amorín, Silvia Barbosa, Pablo Taboada, Alberto Coelho

“…This multi and interdisciplinary work aimed to design and synthesize a novel 3D-printed silica-based porous catalyst functionalized with palladium, evaluate its catalytic performance in isatin drug synthesis, and assess the antiproliferative activity of the resulting compounds against tumor cell lines such as HeLa, MCF-7, and MDA-MB231. …”
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STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma by Dingheng Lu, Yuxiao Li, Xinyang Niu, Jiazhu Sun, Weitao Zhan, Yuchen Shi, Kai Yu, Suyuelin Huang, Xiaoyan Liu, Liping Xie, Xueyou Ma, Ben Liu

“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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Research on Quantitative Analysis Method of Infrared Spectroscopy for Coal Mine Gases by Feng Zhang, Yuchen Zhu, Lin Li, Suping Zhao, Xiaoyan Zhang, Chaobo Chen

“…For gases with distinct absorption peaks, three spectral lines, including the absorption peak and its adjacent troughs, were selected for quantitative analysis. …”
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EIF2S1 in Urinary Extracellular Vesicles as a Novel Diagnostic Marker for Bladder Cancer by Eisuke Tomiyama, Kazutoshi Fujita, Kyosuke Matsuzaki, Ryohei Narumi, Makoto Matsushita, Yujiro Hayashi, Mamoru Hashimoto, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takafumi Minami, Tetsuya Takao, Shingo Takada, Hirotsugu Uemura, Jun Adachi, Takeshi Tomonaga, Norio Nonomura

“…Additionally, EV‐EIF2S1 distinguished patients with BCa from those without BCa and hematuria in a suitable manner (ROCAUC: 0.92). Functional analysis of EIF2S1 in the BCa cell lines (T24 and 5637) showed that EIF2S1 knockdown markedly inhibited cell proliferation and induced cell cycle arrest and apoptosis, suggesting its essentiality for BCa cell growth and survival. …”
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Cloning and identification of human colipase-like 3 and its homologous cDNAs by LU Yan, XUE Yong-chang, YU Peng, WANG Ping-zhang

“…In the present study, we focused on the cloning and identification of a novel cDNA sequence represented by the EST AV 653338 with the encoding product containing two incomplete colipase-like domains, when the electronic prolongation by EST contig was performed.By using mixed cDNAs from human cell lines as templates, we successfully cloned the novel encoding gene sequence, and revealed a novel human colipase-like protein-encoding gene named hCLPSL3 (human colipase-like 3) for there have been two other genes with protein products also containing colipase-like domains registered in the international nucleotide databases, C6ORF126 (namely CLPSL1 here) and C6ORF127 (namely CLPSL2 here). …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…After univariate Cox analysis, prognostic genes were carried out for modeling mitochondria signature (MS) based on 101 combinations of 10 machine learning algorithms. Functional enrichment analysis was performed on this prognostic gene set. …”
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Magnolol Inhibits High Fructose-Induced Podocyte Inflammation via Downregulation of TKFC/Sp1/HDAC4/Notch1 Activation by Ziang Zhou, Yumeng Wang, Yu Xing, Shuman Pan, Wanru Wang, Jie Yang, Wenyuan Wu, Jie Zhou, Luyi Huang, Qiongdan Liang, Dongmei Zhang, Lingdong Kong

“…The chromatin immunoprecipitation (ChIP) assay was performed to evaluate the interaction between Sp1 and the promoter region of HDAC4. …”
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Association mapping of lignin response to Verticillium wilt through an eight-way MAGIC population in Upland cotton by Xiao-min TIAN, Peng HAN, Jing WANG, Pan-xia SHAO, Qiu-shuang AN, Nurimanguli AINI, Qing-yong YANG, Chun-yuan YOU, Hai-rong LIN, Long-fu ZHU, Zhen-yuan PAN, Xin-hui NIE

“…In addition, a genome-wide association study was performed using a Mixed Linear Model (MLM) for LRVW. …”
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Identification of salinity-related genes in ENO2 mutant (eno2−) of Arabidopsis thaliana by Yong-hua ZHANG, Chao CHEN, Zi-han SHI, Hui-mei CHENG, Jie BING, Xiao-feng MA, Chao-xing ZHENG, Hong-jie LI, Gen-fa ZHANG

“…The identified unigenes were subjected to GO analysis to determine biological, molecular, and cellular functions. The biological process was enriched in a total of 20 GO terms, the cellular component was enriched in 13 GO terms, and the molecular function was enriched in 11 GO terms. …”
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PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis by Ning Ma, Wei Chen, Yu Chen, Xiang Wang, Bing Zhu, Kai Ding, Lin Qiu, Jing-jing Li, Jing-Yi Huang, Xin Liang, Yan-Jun Xiang, Qian-Zhi Ni, Zhi-Chao Liu, Qian-Wen Zheng, Yi-Kang Wang, Hui-Jun Cao, Ji Xia, Sheng Xu, Xiao-Song Qiu, Xi-Ran Zhang, Lingyun Long, Zhi-Gang Li, Fan Yao

“…This study aims to identify novel targets for immunotherapy in ESCC.Experimental design ESCC cell lines and mouse models were used to identify the tumor-promoting function of pancreatic progenitor cell differentiation and proliferation factor (PPDPF) and evaluate the effect of blockade of CD24. …”
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Explaining the Comprehensive Human-To-Human Marketig System in the Health Tourism Industry by Ali Pourang, Meysam Shirkhodaie, Mahmood Yahyazadeh far, Mohsen Alizadeh San, Masoomeh Tavangar

“…The aim of this research is to explain a comprehensive human-to-human marketing system in the health tourism industry in line with Iran's cultural identity and legal and institutional conditions. …”
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Deciphering the interaction between the expression of LRP2 served as a mitochondrial metabolism-related gene and prognosis in colon cancer integrating multi-omics analysis by Jie Zhang, Ziyun Liu, Xiaoqing Ma, Zhenyu Shi, Jing Zhao, Yongjie Xie, Xiaobin Shang, Xia Zhang

“…LRP2 could extensively facilitate the proliferation ability of colon cell lines.…”
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The transcription factor PbeNAC83 positively regulates the Valsa canker resistance in apple and pear by DOU Zhiqi, CAI Minrui, DU Chenglong, HU Huanhuan, ZUO Cunwu

“…PbeNAC83 was transfected into the DuliG03 suspension cells, and three wellgrown overexpression cell lines were obtained. Functional analysis demonstrated that PbeNAC83-OE cells were more resistant to Vp and VpM compared to the control. …”
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