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1521
Software Implementation of the Epps-Pulley Criterion in Matlab Modeling Environment
Published 2025-01-01“…The matrix-vector method requires fewer lines of code by performing calculations using linear algebra operations on matrices and vectors. …”
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1522
A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response
Published 2025-01-01“…We investigated correlations between ZNF32 expression and various factors such as prognosis, immune infiltration, immunotherapy, DNA methylation, and biological functions. Furthermore, we performed in vitro research to validate the significance of ZNF32 in head and neck cancer (HNSC). …”
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1523
MRPL21-PARP1 axis promotes cisplatin resistance in head and neck squamous cell carcinoma by inhibiting autophagy through the PI3K/AKT/mTOR signaling pathway
Published 2025-07-01“…Human HNSCC tissues, cell lines, and xenograft models in nude mice were used to explore the expression and function of MRPL21. …”
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1524
Unraveling anoikis in glioblastoma: insights from single-cell sequencing and prognostic modeling
Published 2025-03-01“…Methods Utilizing single-cell sequencing and bulk-transcriptome sequencing data from TCGA, GEO, and CGGA databases, we performed comprehensive bioinformatics analyses. We identified anoikis-related genes, constructed a prognostic model using 101 machine learning algorithms, and validated its clinical utility across multiple cohorts.Finally, we also verified the expression of model genes and the function of key gene in clinical samples and cell lines. …”
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1525
Modulation of RASD2 by miRNA‐485‐5p Drives Thyroid Cancer Progression and Metastasis
Published 2025-06-01“…Immunohistochemical staining and quantitative reverse transcription PCR (qRT‐PCR) validated these findings in clinical specimens and cell lines. Functional characterization of RASD2 was performed through loss‐of‐function studies, examining cellular proliferation, invasion, and glycolytic parameters. …”
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1526
Silencing of STEAP3 suppresses cervical cancer cell proliferation and migration via JAK/STAT3 signaling pathway
Published 2024-12-01“…Despite the importance of the STEAP gene family in tumor progression, the function of STEAP3 in cervical cancer (CC) remains unclear. …”
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1527
LINC01094 promotes gastric cancer through dual targeting of CDKN1A by directly binding RBMS2 and HDAC1
Published 2024-12-01“…However, the biological functions and molecular mechanisms of lncRNAs in gastric cancer (GC) remain to be elucidated in depth. …”
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1528
Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway
Published 2025-07-01“…RNA sequencing was performed to investigate the potential molecular events regulated by PVT1. …”
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1529
Identification and validation of LDHA and SLC16A1 for predicting prognosis and diagnosis in lower-grade glioma
Published 2025-08-01“…Gene set enrichment analysis (GSEA) of single gene was utilized to explore the potential biological function of the two genes. The protein levels of LDHA and SLC16A1 were analyzed using the Human Protein Atlas database. …”
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1530
Overexpression and oncogenic role of RIPK3 in acute myeloid leukemia associated with specific subtypes and treatment outcome
Published 2025-02-01“…Subsequently, we further performed functional experiments in vitro confirmed the potential oncogenic role of RIPK3 in AML. …”
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1531
Chromosome X Open Reading Frame 38 (CXorf38) Is a Tumor Suppressor and Potential Prognostic Biomarker in Lung Adenocarcinoma: The First Characterization
Published 2025-06-01“…Cell proliferation and colony formation assays were used to examine the function of CXorf38 by overexpressing the gene in lung adenocarcinoma cell lines. …”
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1532
C1qtnf6 Expression as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma: Implications for Immune Infiltration and Tumor Progression
Published 2025-06-01“…This study aimed to explore the function of C1qtnf6 in lung adenocarcinoma (LUAD) progression. …”
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1533
Shared hub genes in membranous nephropathy and kidney renal clear cell carcinoma: investigating molecular overlap and tumor progression
Published 2025-06-01“…Higher FYN and LGALS8 expression were linked to poorer survival. miRNA downregulation was validated in KIRC cell lines. Functional analysis revealed that FYN and LGALS8 promote KIRC progression through the ErbB signaling pathway, and knockdown experiments reduced cell proliferation, migration, and colony formation. …”
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1534
Susceptibility to chronic mucus hypersecretion, a genome wide association study.
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1535
Screening and Analysis of Proteins Interacting with TaPDK from Physiological Male Sterility Induced by CHA in Wheat
Published 2013-06-01“…Finally, 24 colonies were obtained, including eight genes, namely non-specific lipid-transfer protein precursor (TanLTP), polyubiquitin (TaPUbi), glyceraldehyde-3-phosphate dehydrogenase, proliferating cell nuclear antigen (TaPCNA), CBS domain containing protein (TaCBS), actin, guanine nucleotide-binding protein beta subunit, chalcone synthase, and three new genes with unknown function. The results of quantitative RT-PCR showed that the expression levels of TanLTP, TaPUbi, and TaPCNA were obviously up-regulated in PHYMS anther, and TaCBS expression was only increased at the tricellular stage in PHYMS anther compared with in fertile lines. …”
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1536
USP15 Drives NSCLC Progression and Chemoresistance, Potentially via Regulation of the U2‐Type Spliceosomal Complex
Published 2025-08-01“…Western blotting was performed to evaluate USP15 protein levels in various NSCLC cell lines. …”
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1537
Hybridization of ADM-Type Rail Service Cars for Enhanced Efficiency and Environmental Sustainability
Published 2025-05-01“…Additionally, the hybrid technology enhances operational flexibility, allowing seamless functionality on both electrified and non-electrified railway lines. …”
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1538
PTK6 mediated immune signatures revealed by single cell transcriptomic and multi omics big data analysis in cervical cancer
Published 2025-08-01“…PTK6 expression was validated in H8 and HeLa cell lines via RT-qPCR and siRNA knockdown experiments. …”
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1539
Dynamic measurements to assess stress levels on buried hydraulic structures
Published 2024-12-01“…The problem becomes more sophisticated when dealing with vital buried hydraulic structures under continuous functional operation while bearing additional loads from running public services such as railways. …”
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1540
Improved MViTv2-T model for insulator defect detection
Published 2025-01-01“…Insulators play a crucial role in transmission lines. Insulators exposed to natural environments are prone to various malfunctions. …”
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