-
1381
-
1382
Energy saving in rail transport
Published 2021-07-01“…Energetic calculation in the simulation are performed using so called "exact method" developed at the Faculty of Transportation. …”
Get full text
Article -
1383
DART-HRMS for the Rapid Assessment of Bioactive Compounds in Ultrasound-Processed Rapeseed Meal By-Product
Published 2025-05-01“…In line with the recommended European policy for a zero-waste crop supply chain, a lab-pilot optimisation process to valorise the by-products of industrially produced rapeseed meal (RM) was performed. …”
Get full text
Article -
1384
PcG-mediated higher-order chromatin structures modulate replication programs at the Drosophila BX-C.
Published 2013-01-01“…Accordingly, replication timing analysis performed on two Drosophila cell lines differing for BX-C gene expression states, PcG distribution, and chromatin domain conformation revealed a cell-type-specific replication program that mirrors lineage-specific BX-C higher-order structures. …”
Get full text
Article -
1385
SNP haplotype mapping in a small ALS family.
Published 2009-05-01“…Panels of haploid-cell lines were generated and a 5 centimorgan (cM) short tandem repeat polymorphism (STRP) genome scan was performed. …”
Get full text
Article -
1386
Study on Antiviral Activity and Pharmacological Safety of Double-Stranded Ribonucleic Acid for Intranasal Administration
Published 2022-12-01“…Interferon inducers are of interest as the first line of defense against viral infections, including influenza. …”
Get full text
Article -
1387
Targeted Delivery of Bortezomib Using Retinoid-Based Nanoparticle: Modulating Liver Fibrosis through the TGF-β1/Smad3 Pathway
Published 2025-04-01“…Purpose: Hepatic stellate cells (HSCs) play a crucial role in fibrosis progression. we have developed a targeted delivery approach using A-functionalized nanoparticles for bortezomib (BTZ) specifically for activated HSCs in a mouse model of liver fibrosis. …”
Get full text
Article -
1388
A survey of reinforcement and deep reinforcement learning for coordination in intelligent traffic light control
Published 2025-04-01“…The analysis of each technique, the learning of its strengths and limitations, in order to evaluate at which levels, they satisfy the requirements of urban traffic. The paper also lines some of the simulators, which perform adaptive traffic. …”
Get full text
Article -
1389
Rapidly Progressing Radicular Cyst in an Endodontically Treated Tooth: Diagnostic Challenges, Advanced Imaging, and Surgical Management
Published 2025-04-01“…It emphasizes the effectiveness of surgical management in resolving such endodontic lesions while maintaining tooth function.…”
Get full text
Article -
1390
Epilepsy protein myoclonin1 interacts with inositol 1,4,5-trisphosphate receptor and reduces calcium ions stored in endoplasmic reticulum
Published 2025-07-01“…Because of the involvement of inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) in epileptic phenotypes and the involvement of myoclonin1 in calcium ions (Ca2+) signaling, we investigated possible functional interplay between myoclonin1 and IP3R1. Methods: We performed immunohistochemical staining of brain tissues and co-immunoprecipitation assay of myoclonin1 and IP3R1, and Ca2+ imaging analyses using human HeLa.S3, mouse embryonic fibroblasts, or glial cells derived from Efhc1 homozygous knockout (Efhc1–/–) and wild-type (WT) littermates. …”
Get full text
Article -
1391
Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A
Published 2025-04-01“…To test the efficacy of the ASOs, we performed lipofectamine transfections of MDA-MB-231 breast cancer, 22Rv1 prostate carcinoma, and Hs822.T Ewing sarcoma cell lines. …”
Get full text
Article -
1392
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway
Published 2025-04-01“…A stable PRDX2-knockdown triple-negative breast cancer cell line was established using lentiviral technology. …”
Get full text
Article -
1393
GPU Acceleration for FHEW/TFHE Bootstrapping
Published 2024-12-01“… Fully Homomorphic Encryption (FHE) allows computations to be performed directly on encrypted data without decryption. …”
Get full text
Article -
1394
Prognostic value of Osteopontin (SPP1) in colorectal carcinoma requires a personalized molecular approach
Published 2019-09-01“…SPP1 has several isoforms, tissue localizations and molecular functions, signaling pathways, and downstream molecular functions. …”
Get full text
Article -
1395
Mutation Scanning in Wheat by Exon Capture and Next-Generation Sequencing.
Published 2015-01-01“…Targeted Induced Local Lesions in Genomes (TILLING) is a reverse genetics approach to identify novel sequence variation in genomes, with the aims of investigating gene function and/or developing useful alleles for breeding. …”
Get full text
Article -
1396
E3 ubiquitin-protein ligase CBL inhibits non-small cell lung cancer progression via ubiquitination and degradation of KDR
Published 2025-06-01“…Results CBL expression was markedly reduced in NSCLC tissues and cell lines relative to normal equivalents. Gain- and loss-of-function tests demonstrated that CBL suppressed the NSCLC cell proliferation, migration, and invasion, highlighting its tumor-suppressive role. …”
Get full text
Article -
1397
Construction of an immunogenic cell death-related LncRNA signature to predict the prognosis of patients with lung adenocarcinoma
Published 2024-11-01“…CCK-8 and transwell assays were performed to study biological function of AC245014.3. …”
Get full text
Article -
1398
SPP1+ macrophages promote head and neck squamous cell carcinoma progression by secreting TNF-α and IL-1β
Published 2024-12-01“…Thus, we constructed SPP1-OE macrophages and SPP1-KD macrophages (both differentiated from THP-1 cells), performed a Luminex liquid suspension chip detection assay to detect differential cytokines, and further assessed their biological functions and mechanisms in several HNSCC cell lines and adjacent macrophages. …”
Get full text
Article -
1399
Alum-anchored IL-12 combined with cytotoxic chemotherapy and immune checkpoint blockade enhanced antitumor immune responses in head and neck cancer models
Published 2024-10-01“…For MOC1, flow cytometry and cytokine array were performed to assess the immune effector functions associated with the combinational treatment. …”
Get full text
Article -
1400
Identification of Genes Predicting Poor Response of Trastuzumab in Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer
Published 2022-01-01“…Differentially expressed genes (DEGs) between the pathological complete response (pCR) group and non-pCR group in a trastuzumab neoadjuvant therapy cohort and DEGs between Herceptin-resistant and wild-type cell lines were detected and evaluated. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analyses were performed to select the functional hub genes. …”
Get full text
Article