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1341
Collapsible properties of Q2 loess and its collapsible prediction model
Published 2025-01-01“…The collapsible coefficients under different water contents were measured by using double-line method tests, and the collapsibility of Q2 loess of different water contents and pressures within high pressure range were investigated. …”
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1342
The efficacy of ferroptosis-inducing compounds IKE and RSL3 correlates with the expression of ferroptotic pathway regulators CD71 and SLC7A11 in biliary tract cancer cells.
Published 2024-01-01“…Potential biomarkers of ferroptosis sensitivity were then assessed via western blot analysis, a rtPCR panel and functional assay kits.<h4>Results</h4>The study found that different FINs reduced cell viability in a cell line-dependent manner. …”
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1343
ZFAS1/STAT3 axis modulates imatinib resistance of chronic myeloid leukemia cells through glucose metabolism reprogramming
Published 2025-07-01“…Imatinib mesylate (IM), a first-generation tyrosine kinase inhibitor (TKI) specifically targeting the BCR-ABL1 oncoprotein, represents the standard first-line therapy for patients with CML. However, imatinib resistance remains a major therapeutic challenge.ObjectiveThis study aims to elucidate the role of the ZFAS1/STAT3 signaling axis in mediating imatinib resistance in CML by promoting metabolic reprogramming, with a particular focus on alterations in glucose metabolism.MethodsImatinib-resistant (IM-R) K562 cells were used to investigate the functional role of ZFAS1gene. …”
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1344
Implementation of Autonomous Navigation for Solar-Panel-Cleaning Vehicle Based on YOLOv4-Tiny
Published 2025-04-01“…The system utilizes the YOLOv4-Tiny object detection model to detect white lines on the solar panels and combines the model with a proportional–integral–derivative (PID) controller to achieve autonomous navigation functionality. …”
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1345
Investigating broadband filtering power amplifier using multi-mode resonator-based bandpass filter
Published 2025-06-01“…This integration significantly reduces circuit size, minimizes signal loss, and enhances overall performance. The BPF design utilizes a multi-mode resonator featuring four transmission zeros and five poles, constructed with series-coupled lines and a shunt stepped-impedance open stub. …”
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1346
MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer
Published 2022-11-01“…Abstract The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to cancer progression. …”
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1347
Does Aspirin Increase Risk of Bleeding in Patients Undergoing Skin Lesion Excision: A Systematic Review and Meta-Analysis
Published 2025-05-01“…Cutaneous lesion excision is frequently performed for diagnosis and treatment of malignancies, as well as for aesthetic or functional benefits. …”
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1348
The Effect of Physiotherapy on Arthrogenic Muscle Inhibition After ACL Injury or Reconstruction: A Systematic Review
Published 2024-12-01“…Structured exercise should be the first-line intervention, but combining it with other therapies enhances rehabilitation. …”
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1349
ALKBH5 Promotes Breast Cancer Stemness Through Regulating Wnt/&beta;-Catenin Signaling
Published 2025-06-01“…The N6-methyladenylate methylation (m6A) demethylase alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 (ALKBH5) decreases modification of RNA, while its role in regulating breast cancer development remains unclear.Methods: ALKBH5-silenced breast cancer cell-line MCF-7 was constructed to investigate its functional impact. …”
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1350
Towards Parkinson’s Disease Detection Through Analysis of Everyday Handwriting
Published 2025-02-01“…Features extracted from time-dependent signals are represented following two strategies, one based on statistical functionals and the other one based on creating Gaussian Mixture Models (GMMs). …”
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1351
Study of phenotypic and cytotoxic properties of erythroid cells of the spleen under hematopoiesis-stimulating effects
Published 2023-06-01“…In recent years, research has revealed a wide variety of erythroid cell functions, including modulation of innate and adaptive immune responses. …”
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1352
Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat
Published 2025-03-01“…The objective of this study was to identify functional candidate genes for fatty acid profiles of the breast meat of the Korean native chicken-red-brown line (KNC-R) through genome-wide association studies. …”
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1353
Diagnostics of progression of liver fibrosis in patients with non-alcoholic steatohepatitis combined with obesity and chronic calculous cholecystitis.
Published 2020-04-01“…Evaluation of the stage of LF in patients with NASH combined with obesity and chronic calculous cholecystitis, which was determined using discriminant functions calculated from laboratory data (OPT, OPF, OPB, ALT, AST / ALT ratio and PTT), is very much in line with the corresponding results of histopathological studies of liver biopsy samples.…”
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1354
EVALUATION OF STUDENTS’ IMAGES OF CITY CENTER: AKSARAY-TURKEY
Published 2019-07-01“…Astronomical signs are abstract in shape (points, lines, circles), but are specific in content (as they perform the function of changing space-time). …”
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1355
EVALUATION OF STUDENTS’ IMAGES OF CITY CENTER: AKSARAY-TURKEY
Published 2019-07-01“…Astronomical signs are abstract in shape (points, lines, circles), but are specific in content (as they perform the function of changing space-time). …”
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1356
Botulinum toxin type A for amyotrophic lateral sclerosis lower limb spasm: two case reports
Published 2025-07-01“…Botulinum toxin type A (BTX-A) is a first-line drug for spastic management. However, there are limited reports on its effectiveness in reducing muscle tone among ALS patients, with scarcely any related research conducted in China. …”
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1357
Disk Kinematics at High Redshift: DysmalPy’s Extension to 3D Modeling and Comparison with Different Approaches
Published 2024-01-01“…Spatially resolved emission-line kinematics are invaluable for investigating fundamental galaxy properties and have become increasingly accessible for galaxies at z ≳0.5 through sensitive near-infrared imaging spectroscopy and millimeter interferometry. …”
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1358
Effects of Acidic Polysaccharide-Enriched Extracts from <i>Holothuria tubulosa</i> on Two- and Three-Dimensional Invasive Breast Cancer Cell Models
Published 2025-03-01“…In this study, we investigated the effects of two acidic polysaccharide-enriched (APs) fractions (Ht1 and Ht2) from the sea cucumber species <i>Holothuria tubulosa</i> on the highly invasive cell line MDA-MB-231. Functional assays were performed to assess cell viability, migratory potential, adhesion on collagen I, and cell morphology, alongside gene expression analysis. …”
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1359
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27‐Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss
Published 2025-06-01“…Osteogenic differentiation assays, Alizarin Red S and ALP staining, western blot analysis, and qRT‐PCR were performed using osteoblast cell lines (C3H10 and C2C12). …”
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1360
CSRP2 promotes the glioblastoma mesenchymal phenotype via p130Cas-mediated NF-κB and MAPK pathways
Published 2025-08-01“…Microscale thermophoresis assay was used to analyze whether mitoxantrone (MTO) and CSRP2 could bind. MTO function was determined by a series of functional tests in vitro, while the relation between MTO and PMT markers, NF-κB and MAPK signaling-related proteins, and apoptosis-related proteins was analyzed by WB in GBM cell lines stably overexpressing CSRP2. …”
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